{"id":"https://openalex.org/W2019493515","doi":"https://doi.org/10.1039/p29930000451","title":"Study of hydrogen bonding in 1-ethyl-2-methyl-4-oxo-1,4-dihydro-pyridin-3-yloxyethanoic acid and 3-(1,2-diethyl-4-oxo-1,4-dihydropyridin-3-yloxy)propanoic acid by 1H NMR spectroscopy and X-ray crystallography","display_name":"Study of hydrogen bonding in 1-ethyl-2-methyl-4-oxo-1,4-dihydro-pyridin-3-yloxyethanoic acid and 3-(1,2-diethyl-4-oxo-1,4-dihydropyridin-3-yloxy)propanoic acid by 1H NMR spectroscopy and X-ray crystallography","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W2019493515","doi":"https://doi.org/10.1039/p29930000451","mag":"2019493515"},"language":"en","primary_location":{"id":"doi:10.1039/p29930000451","doi":"https://doi.org/10.1039/p29930000451","is_oa":false,"landing_page_url":"https://doi.org/10.1039/p29930000451","pdf_url":null,"source":{"id":"https://openalex.org/S4210187049","display_name":"Journal of the Chemical Society Perkin Transactions 2","issn_l":"0300-9580","issn":["0300-9580","1364-5471","1472-779X","2050-8239"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Chemical Society, Perkin Transactions 2","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001782654","display_name":"Paul S. Dobbin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul S. Dobbin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020843793","display_name":"Robert C. Hider","orcid":"https://orcid.org/0000-0003-1330-5797","observed_orcids":["https://orcid.org/0000-0003-1330-5797"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert C. Hider","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111752204","display_name":"S. K. RIZVI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Safia K. Rizvi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036394619","display_name":"Kim L. Maki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kim L. Maki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111546579","display_name":"Dick Van der Helm","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dick van der Helm","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2745,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.43403463,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":"3","first_page":"451","last_page":"451"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10798","display_name":"Crystallography and molecular interactions","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10798","display_name":"Crystallography and molecular interactions","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10464","display_name":"Crystal structures of chemical compounds","score":0.006300000008195639,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12410","display_name":"Structural and Chemical Analysis of Organic and Inorganic Compounds","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hydrogen-bonding","display_name":"hydrogen bonding","score":0.9589999914169312},{"id":"https://openalex.org/keywords/intramolecular-hydrogen-bonding","display_name":"intramolecular hydrogen bonding","score":0.8399999737739563},{"id":"https://openalex.org/keywords/intermolecular-hydrogen-bonding","display_name":"intermolecular hydrogen bonding","score":0.9700000286102295},{"id":"https://openalex.org/keywords/crystal-structure","display_name":"crystal structure","score":0.5830000042915344},{"id":"https://openalex.org/keywords/dmso-solution","display_name":"DMSO solution","score":0.6359999775886536}],"concepts":[{"id":"https://openalex.org/C2779761105","wikidata":"https://www.wikidata.org/wiki/Q422956","display_name":"Propanoic acid","level":2,"score":0.9831290245056152},{"id":"https://openalex.org/C112887158","wikidata":"https://www.wikidata.org/wiki/Q169324","display_name":"Hydrogen bond","level":3,"score":0.8536810874938965},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8398579359054565},{"id":"https://openalex.org/C2780378348","wikidata":"https://www.wikidata.org/wiki/Q25351438","display_name":"Ring (chemistry)","level":2,"score":0.7808908224105835},{"id":"https://openalex.org/C75079739","wikidata":"https://www.wikidata.org/wiki/Q1571801","display_name":"Intramolecular force","level":2,"score":0.7571666240692139},{"id":"https://openalex.org/C54516573","wikidata":"https://www.wikidata.org/wiki/Q2294","display_name":"Proton","level":2,"score":0.470266193151474},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.46206387877464294},{"id":"https://openalex.org/C2994242795","wikidata":"https://www.wikidata.org/wiki/Q101487","display_name":"Ethyl ester","level":2,"score":0.45521730184555054},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.45345115661621094},{"id":"https://openalex.org/C512968161","wikidata":"https://www.wikidata.org/wiki/Q556","display_name":"Hydrogen","level":2,"score":0.45267558097839355},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.3715474009513855},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.23890188336372375},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1039/p29930000451","doi":"https://doi.org/10.1039/p29930000451","is_oa":false,"landing_page_url":"https://doi.org/10.1039/p29930000451","pdf_url":null,"source":{"id":"https://openalex.org/S4210187049","display_name":"Journal of the Chemical Society Perkin Transactions 2","issn_l":"0300-9580","issn":["0300-9580","1364-5471","1472-779X","2050-8239"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Chemical Society, Perkin Transactions 2","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W30168135","https://openalex.org/W1969120793","https://openalex.org/W2018090435","https://openalex.org/W2039534318","https://openalex.org/W2054145401","https://openalex.org/W2064789173","https://openalex.org/W2065322100","https://openalex.org/W2066575358","https://openalex.org/W2095490030","https://openalex.org/W2269760103","https://openalex.org/W2395577675","https://openalex.org/W2411088972"],"related_works":["https://openalex.org/W2009584799","https://openalex.org/W1507622146","https://openalex.org/W2023408181","https://openalex.org/W1981039820","https://openalex.org/W2950107513","https://openalex.org/W2078676469","https://openalex.org/W1995200552","https://openalex.org/W2109183545","https://openalex.org/W1770062539","https://openalex.org/W2043522105"],"abstract_inverted_index":{"A":[0],"series":[1],"of":[2,32],"1,2-dialkyl-4-oxo-1,4-dihydropyridin-3-yloxyethanoic":[3],"acids":[4,7],"and":[5,28,64,86],"3-(1,2-dialkyl-4-oxo-1,4-dihydropyridin-3-yloxy)propanoic":[6],"have":[8],"been":[9],"synthesized":[10],"via":[11],"the":[12,23,29,33,40,49],"corresponding":[13],"pyran-4-ones.":[14],"Ring":[15],"proton":[16,27],"chemical":[17],"shifts":[18],"indicate":[19],"hydrogen":[20,50,74],"bonding":[21,51,75],"between":[22],"side-chain":[24],"carboxylic":[25],"acid":[26,55,78],"4-oxo":[30],"group":[31],"heterocycle":[34],"to":[35,56],"be":[36,57],"present":[37],"only":[38],"for":[39],"pyridinone":[41],"species":[42],"in":[43,52,76],"DMSO":[44],"solution.":[45],"X-Ray":[46],"crystallography":[47],"demonstrates":[48],"1":[53],"-ethyl-2-methyl-4-oxo-1,4-dihydropyridin-3-yloxyethanoic":[54],"very":[58],"strong":[59,81],"(O\u2014O":[60,82],"=":[61,83],"2.441":[62],"\u00c5)":[63,85],"intramolecular,":[65],"giving":[66,88],"a":[67],"unique":[68],"8-membered":[69],"chelate":[70],"ring.":[71],"The":[72],"analogous":[73],"3-(1,2-diethyl-4-oxo-1,4-dihydropyridin-3-yloxy)propanoic":[77],"is":[79],"however":[80],"2.541":[84],"inter-molecular,":[87],"an":[89],"infinite":[90],"structure.":[91]},"counts_by_year":[],"updated_date":"2026-07-28T07:46:37.118299","created_date":"2016-06-24T00:00:00"}