{"id":"https://openalex.org/W2019312609","doi":"https://doi.org/10.1097/00007890-199802150-00013","title":"UTILITY OF STANDARDIZED HISTOLOGICAL CLASSIFICATION IN THE MANAGEMENT OF ACUTE REJECTION1","display_name":"UTILITY OF STANDARDIZED HISTOLOGICAL CLASSIFICATION IN THE MANAGEMENT OF ACUTE REJECTION1","publication_year":1998,"publication_date":"1998-02-01","ids":{"openalex":"https://openalex.org/W2019312609","doi":"https://doi.org/10.1097/00007890-199802150-00013","mag":"2019312609","pmid":"https://pubmed.ncbi.nlm.nih.gov/9484754"},"language":"en","primary_location":{"id":"doi:10.1097/00007890-199802150-00013","doi":"https://doi.org/10.1097/00007890-199802150-00013","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00007890-199802150-00013","pdf_url":null,"source":{"id":"https://openalex.org/S11564597","display_name":"Transplantation","issn_l":"0041-1337","issn":["0041-1337","1534-6080"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110768036","display_name":"Lillian W. Gaber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lillian W. Gaber","raw_affiliation_strings":["Department of Pathology, The University of Tennessee-Memphis, 38103, USA","Department of Pathology, The University of Tennessee-Memphis","Lillian W. Gaber, MD, Department of Pathology, The University of Tennessee-Memphis, 800 Madison Avenue, Memphis, TN 38103"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The University of Tennessee-Memphis, 38103, USA","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"Department of Pathology, The University of Tennessee-Memphis","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"Lillian W. Gaber, MD, Department of Pathology, The University of Tennessee-Memphis, 800 Madison Avenue, Memphis, TN 38103","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006737510","display_name":"Linda W. Moore","orcid":"https://orcid.org/0000-0003-2519-5150","observed_orcids":["https://orcid.org/0000-0003-2519-5150"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Linda W. Moore","raw_affiliation_strings":["Department of Surgery, The University of Tennessee-Memphis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, The University of Tennessee-Memphis","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001506348","display_name":"Ahmed Osama Gaber","orcid":"https://orcid.org/0000-0002-0743-4974","observed_orcids":["https://orcid.org/0000-0002-0743-4974","https://orcid.org/0000-0002-9444-3202"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"A. Osama Gaber","raw_affiliation_strings":["Department of Surgery, The University of Tennessee-Memphis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, The University of Tennessee-Memphis","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026208455","display_name":"Martin Roy First","orcid":"https://orcid.org/0000-0003-2290-4142","observed_orcids":["https://orcid.org/0000-0003-2290-4142"]},"institutions":[{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Roy First","raw_affiliation_strings":["Division of Nephrology, University of Cincinnati"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology, University of Cincinnati","institution_ids":["https://openalex.org/I63135867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002335294","display_name":"Ronald D. Guttmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ronald D. Guttmann","raw_affiliation_strings":["McGill Centre for Clinical Immunobiology and Transplantation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"McGill Centre for Clinical Immunobiology and Transplantation","institution_ids":["https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017471259","display_name":"Philippe Pouletty","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166433","display_name":"SangStat Medical Corporation","ror":"https://ror.org/05cqhmv85","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3018075036","https://openalex.org/I4210111804","https://openalex.org/I4210166433"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philippe Pouletty","raw_affiliation_strings":["SangStat Medical Corporation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SangStat Medical Corporation","institution_ids":["https://openalex.org/I4210166433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110406270","display_name":"T J Schroeder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy J. Schroeder","raw_affiliation_strings":["University of Cincinnati, Transplant Division"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Cincinnati, Transplant Division","institution_ids":["https://openalex.org/I63135867"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065766935","display_name":"Jean\u2010Paul Soulillou","orcid":"https://orcid.org/0000-0001-7468-5135","observed_orcids":["https://orcid.org/0000-0001-7468-5135"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jean-Paul Soulillou","raw_affiliation_strings":["SangStat Atlantique"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SangStat Atlantique","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5001506348","https://openalex.org/A5110768036"],"corresponding_institution_ids":["https://openalex.org/I160606119"],"apc_list":null,"apc_paid":null,"fwci":4.9081,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":{"value":0.95313247,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"65","issue":"3","first_page":"376","last_page":"380"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11163","display_name":"Organ Donation and Transplantation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-kidney-transplant-rejection","display_name":"acute kidney transplant rejection","score":0.7490000128746033},{"id":"https://openalex.org/keywords/banff-classification","display_name":"Banff classification","score":0.8489999771118164},{"id":"https://openalex.org/keywords/histological-grading","display_name":"histological grading","score":0.6970000267028809},{"id":"https://openalex.org/keywords/kidney-biopsy","display_name":"renal biopsy","score":0.5410000085830688},{"id":"https://openalex.org/keywords/corticosteroid-response","display_name":"corticosteroid response","score":0.7940000295639038},{"id":"https://openalex.org/keywords/graft-survival","display_name":"graft survival","score":0.781000018119812},{"id":"https://openalex.org/keywords/rejection-severity","display_name":"rejection severity","score":0.7639999985694885},{"id":"https://openalex.org/keywords/serum-creatinine","display_name":"serum creatinine","score":0.718999981880188}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8023812174797058},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.6787151098251343},{"id":"https://openalex.org/C2780252810","wikidata":"https://www.wikidata.org/wiki/Q1455316","display_name":"Immunosuppression","level":2,"score":0.6218768954277039},{"id":"https://openalex.org/C2777286243","wikidata":"https://www.wikidata.org/wiki/Q5591926","display_name":"Grading (engineering)","level":2,"score":0.5851108431816101},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.571629524230957},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.543952465057373},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5073868632316589},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.44723278284072876},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3616727292537689},{"id":"https://openalex.org/C147176958","wikidata":"https://www.wikidata.org/wiki/Q77590","display_name":"Civil engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006652","descriptor_name":"Histological Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/00007890-199802150-00013","doi":"https://doi.org/10.1097/00007890-199802150-00013","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00007890-199802150-00013","pdf_url":null,"source":{"id":"https://openalex.org/S11564597","display_name":"Transplantation","issn_l":"0041-1337","issn":["0041-1337","1534-6080"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"journal-article"},{"id":"pmid:9484754","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9484754","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.6499999761581421,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1983268003","https://openalex.org/W2076201260","https://openalex.org/W2089988463","https://openalex.org/W2092577658","https://openalex.org/W2121454052","https://openalex.org/W2395024757","https://openalex.org/W2405902037","https://openalex.org/W2408532267","https://openalex.org/W2410779616","https://openalex.org/W2415844485","https://openalex.org/W2433772465"],"related_works":["https://openalex.org/W2257873131","https://openalex.org/W6910612118","https://openalex.org/W2001635665","https://openalex.org/W2112841187","https://openalex.org/W2121454052","https://openalex.org/W1984188777","https://openalex.org/W4245598207","https://openalex.org/W3011635649","https://openalex.org/W2079336836","https://openalex.org/W4390698590"],"abstract_inverted_index":{"BACKGROUND:":[0],"Standardized":[1],"histological":[2],"grading":[3,59,94,151],"of":[4,15,24,53,55,65,73,79,125,140,219,240,250],"transplant":[5,26,40],"kidney":[6,39],"biopsies":[7],"has":[8],"become":[9],"a":[10,233],"primary":[11],"criterion":[12],"for":[13,51,236],"diagnosis":[14],"rejection":[16,66,74,99,220],"in":[17,35,77,87,253],"immunosuppression":[18],"clinical":[19,63,98,254],"trials.":[20],"METHODS:":[21],"A":[22],"consortium":[23],"19":[25],"centers":[27],"from":[28,43],"North":[29],"America,":[30],"Europe,":[31],"and":[32,67,91,129,174],"Australia":[33],"convened":[34],"1995":[36,45],"to":[37,131,145],"examine":[38],"rejection.":[41],"Data":[42],"the":[44,229,248],"Efficacy":[46],"Endpoints":[47],"Conference":[48],"were":[49,121,134],"examined":[50],"frequency":[52,88],"adoption":[54,85],"Banff":[56,83,93,126,150,192,230,251],"schema.":[57],"Biopsy":[58],"was":[60],"correlated":[61,96,153,195],"with":[62,82,97,154,196],"parameters":[64],"therapy":[68,133],"response.":[69],"RESULTS:":[70],"Histological":[71],"confirmation":[72],"episodes":[75],"occurred":[76],"73%":[78],"953":[80],"cases,":[81],"criteria":[84,252],"increasing":[86],"between":[89],"1992":[90],"1995.":[92],"significantly":[95],"severity":[100,221],"(rejection":[101],"creatinine:":[102],"grade":[103,107,111,141,159,163,167,177,181,185,193,203,206,209],"I,":[104,160,178,204],"2.8+/-0.2":[105],"mg/dl;":[106,110,114,162,166,180,184],"II,":[108,164,182,207],"3.5+/-0.2":[109],"III,":[112,168,186,210],"4.1+/-0.3":[113],"P":[115],"<":[116,148,172,190,213],"0.001),":[117,173],"although":[118],"nadir":[119],"creatinines":[120],"similar.":[122],"Response":[123],"rates":[124],"grades":[127],"I":[128],"II":[130],"steroid":[132],"not":[135],"different,":[136],"but":[137],"only":[138],"42%":[139],"III":[142,194],"rejections":[143],"responded":[144],"steroids":[146],"(P":[147,171,189,212],"0.003.":[149],"also":[152],"postrejection":[155],"creatinine,":[156],"day":[157,175],"15:":[158],"2.2+/-0.2":[161,183],"3.0+/-0.2":[165],"3.8+/-0.4":[169],"mg/dl":[170,188],"30:":[176],"2.1+/-0.1":[179],"2.7+/-0.2":[187],"0.06).":[191],"reduced":[197],"graft":[198],"survival":[199],"at":[200],"1":[201],"year:":[202],"86%;":[205],"88%;":[208],"70%":[211],"0.01).":[214],"CONCLUSIONS:":[215],"This":[216],"multicenter":[217],"review":[218],"confirms":[222],"that":[223],"standardized":[224],"histologic":[225],"classifications":[226],"such":[227],"as":[228],"schema":[231],"provide":[232],"reliable":[234],"means":[235],"stratifying":[237],"patient":[238],"risk":[239],"treatment":[241],"success":[242],"or":[243],"failure.":[244],"These":[245],"data":[246],"support":[247],"use":[249],"trial":[255],"design.":[256]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}