{"id":"https://openalex.org/W2019229910","doi":"https://doi.org/10.1074/jbc.m308297200","title":"Biochemical Diversity among the 1-Amino-cyclopropane-1-Carboxylate Synthase Isozymes Encoded by the Arabidopsis Gene Family","display_name":"Biochemical Diversity among the 1-Amino-cyclopropane-1-Carboxylate Synthase Isozymes Encoded by the Arabidopsis Gene Family","publication_year":2003,"publication_date":"2003-11-26","ids":{"openalex":"https://openalex.org/W2019229910","doi":"https://doi.org/10.1074/jbc.m308297200","mag":"2019229910","pmid":"https://pubmed.ncbi.nlm.nih.gov/12968022"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.m308297200","doi":"https://doi.org/10.1074/jbc.m308297200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m308297200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1074/jbc.m308297200","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056791193","display_name":"Takeshi Yamagami","orcid":"https://orcid.org/0000-0003-0269-8062","observed_orcids":["https://orcid.org/0000-0003-0269-8062"]},"institutions":[{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210144282","display_name":"Plant Gene Expression Center","ror":"https://ror.org/03rafms67","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210094889","https://openalex.org/I4210144282","https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Takeshi Yamagami","raw_affiliation_strings":["Plant Gene Expression Center, United States Department of Agriculture, Albany, California 94710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plant Gene Expression Center, United States Department of Agriculture, Albany, California 94710, USA","institution_ids":["https://openalex.org/I1336096307","https://openalex.org/I4210144282"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050841942","display_name":"Atsunari Tsuchisaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144282","display_name":"Plant Gene Expression Center","ror":"https://ror.org/03rafms67","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210094889","https://openalex.org/I4210144282","https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Atsunari Tsuchisaka","raw_affiliation_strings":["Plant Gene Expression Center, Albany, California 94710"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plant Gene Expression Center, Albany, California 94710","institution_ids":["https://openalex.org/I4210144282"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000831132","display_name":"Kayoko Yamada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144282","display_name":"Plant Gene Expression Center","ror":"https://ror.org/03rafms67","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210094889","https://openalex.org/I4210144282","https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kayoko Yamada","raw_affiliation_strings":["Plant Gene Expression Center, Albany, California 94710"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plant Gene Expression Center, Albany, California 94710","institution_ids":["https://openalex.org/I4210144282"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028207580","display_name":"William F. Haddon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210140558","display_name":"Western Regional Research Center","ror":"https://ror.org/03x7fn667","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210094889","https://openalex.org/I4210140558"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William F. Haddon","raw_affiliation_strings":["Food Safety and Health Research Unit, Western Regional Research Center, United States Department of Agriculture, Albany, California 94710"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Food Safety and Health Research Unit, Western Regional Research Center, United States Department of Agriculture, Albany, California 94710","institution_ids":["https://openalex.org/I1336096307","https://openalex.org/I4210140558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110064048","display_name":"Leslie A. Harden","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210140558","display_name":"Western Regional Research Center","ror":"https://ror.org/03x7fn667","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210094889","https://openalex.org/I4210140558"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leslie A. Harden","raw_affiliation_strings":["Food Safety and Health Research Unit, Western Regional Research Center, United States Department of Agriculture, Albany, California 94710"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Food Safety and Health Research Unit, Western Regional Research Center, United States Department of Agriculture, Albany, California 94710","institution_ids":["https://openalex.org/I1336096307","https://openalex.org/I4210140558"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090711057","display_name":"Athanasios Theologis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144282","display_name":"Plant Gene Expression Center","ror":"https://ror.org/03rafms67","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210094889","https://openalex.org/I4210144282","https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Athanasios Theologis","raw_affiliation_strings":["Plant Gene Expression Center, Albany, California 94710"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plant Gene Expression Center, Albany, California 94710","institution_ids":["https://openalex.org/I4210144282"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5090711057"],"corresponding_institution_ids":["https://openalex.org/I4210144282"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":17.5038,"has_fulltext":false,"cited_by_count":358,"citation_normalized_percentile":{"value":0.99310132,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"278","issue":"49","first_page":"49102","last_page":"49112"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10473","display_name":"Postharvest Quality and Shelf Life Management","score":0.6338000297546387,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10473","display_name":"Postharvest Quality and Shelf Life Management","score":0.6338000297546387,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.14980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.07970000058412552,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/1-aminocyclopropane-1-carboxylic-acid-synthase","display_name":"1-aminocyclopropane-1-carboxylate synthase","score":0.9929999709129333},{"id":"https://openalex.org/keywords/isoenzymes","display_name":"isozymes","score":0.7250000238418579},{"id":"https://openalex.org/keywords/ethylene-production","display_name":"ethylene production","score":0.9269999861717224},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.984000027179718},{"id":"https://openalex.org/keywords/enzyme-kinetics","display_name":"enzyme kinetics","score":0.7210000157356262},{"id":"https://openalex.org/keywords/dimers","display_name":"dimers","score":0.597000002861023},{"id":"https://openalex.org/keywords/substrate-specificity","display_name":"substrate specificity","score":0.4659999907016754},{"id":"https://openalex.org/keywords/sinefungin","display_name":"sinefungin","score":0.5509999990463257},{"id":"https://openalex.org/keywords/avg","display_name":"AVG","score":0.3310000002384186},{"id":"https://openalex.org/keywords/aminotransferases","display_name":"transaminases","score":0.7110000252723694},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.5559999942779541},{"id":"https://openalex.org/keywords/tissue-specific-signaling","display_name":"tissue-specific signaling","score":0.5870000123977661}],"concepts":[{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.8664998412132263},{"id":"https://openalex.org/C119795356","wikidata":"https://www.wikidata.org/wiki/Q407801","display_name":"Isozyme","level":3,"score":0.7792375087738037},{"id":"https://openalex.org/C5911399","wikidata":"https://www.wikidata.org/wiki/Q2278983","display_name":"Gene family","level":4,"score":0.7159743309020996},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.710110068321228},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6872516870498657},{"id":"https://openalex.org/C188082640","wikidata":"https://www.wikidata.org/wiki/Q1780899","display_name":"Complementation","level":4,"score":0.6746322512626648},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.6545909643173218},{"id":"https://openalex.org/C34957205","wikidata":"https://www.wikidata.org/wiki/Q277338","display_name":"Pseudogene","level":4,"score":0.554031491279602},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.5071711540222168},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.4550796449184418},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.416156530380249},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3681594133377075},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.34658730030059814},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3061128556728363},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.26329776644706726}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008190","descriptor_name":"Lyases","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D008190","descriptor_name":"Lyases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008190","descriptor_name":"Lyases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1074/jbc.m308297200","doi":"https://doi.org/10.1074/jbc.m308297200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m308297200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:12968022","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12968022","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1074/jbc.m308297200","doi":"https://doi.org/10.1074/jbc.m308297200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m308297200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":83,"referenced_works":["https://openalex.org/W408719783","https://openalex.org/W997490432","https://openalex.org/W1263543344","https://openalex.org/W1494075612","https://openalex.org/W1501973340","https://openalex.org/W1534519444","https://openalex.org/W1553771250","https://openalex.org/W1564923665","https://openalex.org/W1596154245","https://openalex.org/W1771294903","https://openalex.org/W1773196754","https://openalex.org/W1844703505","https://openalex.org/W1847507753","https://openalex.org/W1883396752","https://openalex.org/W1911278511","https://openalex.org/W1938441128","https://openalex.org/W1945358749","https://openalex.org/W1964666615","https://openalex.org/W1974060942","https://openalex.org/W1976095793","https://openalex.org/W1976863477","https://openalex.org/W1978698561","https://openalex.org/W1989477986","https://openalex.org/W1991862319","https://openalex.org/W1993715180","https://openalex.org/W1995774065","https://openalex.org/W1995833610","https://openalex.org/W2000527439","https://openalex.org/W2002164796","https://openalex.org/W2004138355","https://openalex.org/W2005955710","https://openalex.org/W2012103484","https://openalex.org/W2014440450","https://openalex.org/W2014874749","https://openalex.org/W2016295310","https://openalex.org/W2019818430","https://openalex.org/W2020292676","https://openalex.org/W2024747355","https://openalex.org/W2025102743","https://openalex.org/W2031838618","https://openalex.org/W2035544315","https://openalex.org/W2036931862","https://openalex.org/W2038673786","https://openalex.org/W2040816227","https://openalex.org/W2041951055","https://openalex.org/W2053126950","https://openalex.org/W2057238216","https://openalex.org/W2059657252","https://openalex.org/W2059735255","https://openalex.org/W2063968553","https://openalex.org/W2066198289","https://openalex.org/W2069275373","https://openalex.org/W2071553204","https://openalex.org/W2076248833","https://openalex.org/W2079752350","https://openalex.org/W2081360933","https://openalex.org/W2084030119","https://openalex.org/W2085415453","https://openalex.org/W2085878350","https://openalex.org/W2086246918","https://openalex.org/W2088144279","https://openalex.org/W2100837269","https://openalex.org/W2102277656","https://openalex.org/W2106882534","https://openalex.org/W2107730615","https://openalex.org/W2108712457","https://openalex.org/W2109847775","https://openalex.org/W2113275510","https://openalex.org/W2138026076","https://openalex.org/W2142060432","https://openalex.org/W2143922328","https://openalex.org/W2148299987","https://openalex.org/W2150297520","https://openalex.org/W2160084442","https://openalex.org/W2162728101","https://openalex.org/W2166674758","https://openalex.org/W2174475512","https://openalex.org/W2314225431","https://openalex.org/W2418361432","https://openalex.org/W2490637711","https://openalex.org/W2775548375","https://openalex.org/W4232534952","https://openalex.org/W4255904355"],"related_works":["https://openalex.org/W2145239463","https://openalex.org/W2104743494","https://openalex.org/W2104978938","https://openalex.org/W4247656789","https://openalex.org/W1518130370","https://openalex.org/W2082806806","https://openalex.org/W2004026608","https://openalex.org/W2041951055","https://openalex.org/W2013847306","https://openalex.org/W1964666615"],"abstract_inverted_index":{"1-Amino-cyclopropane-1-carboxylate":[0],"synthase":[1],"(ACS,":[2],"EC":[3],"4.4.1.14)":[4],"is":[5,43,48,226],"the":[6,10,19,24,54,80,111,138,218,239,244],"key":[7],"enzyme":[8],"in":[9,14,123,234,252],"ethylene":[11],"biosynthetic":[12],"pathway":[13],"plants.":[15],"The":[16,67,118,135,152,214],"completion":[17],"of":[18,26,113,137,241],"Arabidopsis":[20,81,96,219],"genome":[21],"sequence":[22,147],"revealed":[23],"presence":[25],"twelve":[27],"putative":[28],"ACS":[29,73,82,103,116,119,157,220,231],"genes,":[30,86,104],"ACS1-12,":[31],"dispersed":[32],"among":[33],"five":[34],"chromosomes.":[35],"ACS1-5":[36],"have":[37,163],"been":[38],"previously":[39],"characterized.":[40,134],"However,":[41],"ACS1":[42,78],"enzymatically":[44],"inactive":[45],"whereas":[46,183],"ACS3":[47],"a":[49,253],"pseudogene.":[50],"Complementation":[51],"analysis":[52,153],"with":[53,77],"Escherichia":[55],"coli":[56],"aminotransferase":[57],"mutant":[58],"DL39":[59],"shows":[60,154],"that":[61,155,217,228],"ACS10":[62],"and":[63,75,92,98,107,132,148,162,170,200,208],"12":[64,211],"encode":[65],"aminotransferases.":[66],"remaining":[68],"eight":[69],"genes":[70,74,120],"are":[71,89,222],"authentic":[72],"together":[76],"constitute":[79],"gene":[83],"family.":[84],"All":[85],"except":[87,105],"ACS3,":[88],"transcriptionally":[90],"active":[91],"differentially":[93],"expressed":[94,122],"during":[95],"growth":[97],"development.":[99],"IAA":[100],"induces":[101],"all":[102,114,156],"ACS7":[106],"ACS9;":[108],"CHX":[109],"enhances":[110],"expression":[112],"functional":[115],"genes.":[117],"were":[121],"E.":[124],"coli,":[125],"purified":[126],"to":[127,180,190,205,210,247],"homogeneity":[128],"by":[129,143],"affinity":[130],"chromatography,":[131],"biochemically":[133,223,229],"quality":[136],"recombinant":[139],"proteins":[140],"was":[141],"verified":[142],"N-terminal":[144],"amino":[145],"acid":[146],"MALDI-TOF":[149],"mass":[150],"spectrometry.":[151],"isozymes":[158,221,232],"function":[159,233],"as":[160],"dimers":[161],"an":[164],"optimum":[165],"pH,":[166],"ranging":[167],"between":[168],"7.3":[169],"8.2.":[171],"Their":[172,195],"Km":[173],"values":[174,186,197],"for":[175,198,238],"AdoMet":[176],"range":[177],"from":[178,188,203],"8.3":[179],"45":[181],"microm,":[182,212],"their":[184],"kcat":[185],"vary":[187,202],"0.19":[189],"4.82":[191],"s-1":[192],"per":[193],"monomer.":[194],"Ki":[196],"AVG":[199],"sinefungin":[201],"0.019":[204],"0.80":[206],"microm":[207],"0.15":[209],"respectively.":[213],"results":[215],"indicate":[216],"distinct.":[224],"It":[225],"proposed":[227],"diverse":[230],"unique":[235,250],"cellular":[236],"environments":[237],"biosynthesis":[240],"C2H4,":[242],"permitting":[243],"signaling":[245],"molecule":[246],"exert":[248],"its":[249],"effects":[251],"tissue-":[254],"or":[255],"cell-specific":[256],"fashion.":[257]},"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":20},{"year":2020,"cited_by_count":18},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":17},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":12},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":21},{"year":2013,"cited_by_count":20},{"year":2012,"cited_by_count":17}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}