{"id":"https://openalex.org/W2019175367","doi":"https://doi.org/10.1097/01.alc.0000163509.27577.da","title":"Corticosterone Increases Damage and Cytosolic Calcium Accumulation Associated With Ethanol Withdrawal in Rat Hippocampal Slice Cultures","display_name":"Corticosterone Increases Damage and Cytosolic Calcium Accumulation Associated With Ethanol Withdrawal in Rat Hippocampal Slice Cultures","publication_year":2005,"publication_date":"2005-05-01","ids":{"openalex":"https://openalex.org/W2019175367","doi":"https://doi.org/10.1097/01.alc.0000163509.27577.da","mag":"2019175367","pmid":"https://pubmed.ncbi.nlm.nih.gov/15897733"},"language":"en","primary_location":{"id":"doi:10.1097/01.alc.0000163509.27577.da","doi":"https://doi.org/10.1097/01.alc.0000163509.27577.da","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.alc.0000163509.27577.da","pdf_url":null,"source":{"id":"https://openalex.org/S115510430","display_name":"Alcoholism Clinical and Experimental Research","issn_l":"0145-6008","issn":["0145-6008","1530-0277","2993-7175"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcoholism: Clinical & Experimental Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021502761","display_name":"Patrick J. Mulholland","orcid":"https://orcid.org/0000-0003-0780-5971","observed_orcids":["https://orcid.org/0000-0003-0780-5971"]},"institutions":[{"id":"https://openalex.org/I1310053265","display_name":"St George's Hospital","ror":"https://ror.org/0001ke483","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1310053265","https://openalex.org/I2801196673"]},{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]},{"id":"https://openalex.org/I165862685","display_name":"St George's, University of London","ror":"https://ror.org/040f08y74","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I165862685","https://openalex.org/I4401726869"]},{"id":"https://openalex.org/I2801012209","display_name":"Albert B. Chandler Hospital","ror":"https://ror.org/03r8nx235","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285210727","https://openalex.org/I143302722","https://openalex.org/I2801012209"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Patrick J. Mulholland","raw_affiliation_strings":["Department of Psychology, University of Kentucky, Lexington, Kentucky 40506-0044, USA","Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky","the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH)","the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, University of Kentucky, Lexington, Kentucky 40506-0044, USA","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH)","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I2801012209"]},{"raw_affiliation_string":"the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","institution_ids":["https://openalex.org/I1310053265","https://openalex.org/I165862685"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021222735","display_name":"Rachel L. Self","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1310053265","display_name":"St George's Hospital","ror":"https://ror.org/0001ke483","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1310053265","https://openalex.org/I2801196673"]},{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]},{"id":"https://openalex.org/I165862685","display_name":"St George's, University of London","ror":"https://ror.org/040f08y74","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I165862685","https://openalex.org/I4401726869"]},{"id":"https://openalex.org/I2801012209","display_name":"Albert B. Chandler Hospital","ror":"https://ror.org/03r8nx235","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285210727","https://openalex.org/I143302722","https://openalex.org/I2801012209"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Rachel L. Self","raw_affiliation_strings":["Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky; the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH); and the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky","the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH)","the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky; the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH); and the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I165862685","https://openalex.org/I2801012209"]},{"raw_affiliation_string":"Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH)","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I2801012209"]},{"raw_affiliation_string":"the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","institution_ids":["https://openalex.org/I1310053265","https://openalex.org/I165862685"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110865854","display_name":"Barton R. Harris","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1310053265","display_name":"St George's Hospital","ror":"https://ror.org/0001ke483","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1310053265","https://openalex.org/I2801196673"]},{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]},{"id":"https://openalex.org/I165862685","display_name":"St George's, University of London","ror":"https://ror.org/040f08y74","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I165862685","https://openalex.org/I4401726869"]},{"id":"https://openalex.org/I2801012209","display_name":"Albert B. Chandler Hospital","ror":"https://ror.org/03r8nx235","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285210727","https://openalex.org/I143302722","https://openalex.org/I2801012209"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Barton R. Harris","raw_affiliation_strings":["Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky; the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH); and the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky","the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH)","the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky; the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH); and the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I165862685","https://openalex.org/I2801012209"]},{"raw_affiliation_string":"Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH)","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I2801012209"]},{"raw_affiliation_string":"the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","institution_ids":["https://openalex.org/I1310053265","https://openalex.org/I165862685"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112195037","display_name":"Hilary J. Little","orcid":"https://orcid.org/0009-0005-7678-0845","observed_orcids":["https://orcid.org/0009-0005-7678-0845"]},"institutions":[{"id":"https://openalex.org/I1310053265","display_name":"St George's Hospital","ror":"https://ror.org/0001ke483","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1310053265","https://openalex.org/I2801196673"]},{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]},{"id":"https://openalex.org/I165862685","display_name":"St George's, University of London","ror":"https://ror.org/040f08y74","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I165862685","https://openalex.org/I4401726869"]},{"id":"https://openalex.org/I2801012209","display_name":"Albert B. Chandler Hospital","ror":"https://ror.org/03r8nx235","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285210727","https://openalex.org/I143302722","https://openalex.org/I2801012209"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Hilary J. Little","raw_affiliation_strings":["Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky; the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH); and the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky","the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH)","the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky; the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH); and the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I165862685","https://openalex.org/I2801012209"]},{"raw_affiliation_string":"Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH)","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I2801012209"]},{"raw_affiliation_string":"the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","institution_ids":["https://openalex.org/I1310053265","https://openalex.org/I165862685"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105783220","display_name":"John Martin Littleton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1310053265","display_name":"St George's Hospital","ror":"https://ror.org/0001ke483","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1310053265","https://openalex.org/I2801196673"]},{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]},{"id":"https://openalex.org/I165862685","display_name":"St George's, University of London","ror":"https://ror.org/040f08y74","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I165862685","https://openalex.org/I4401726869"]},{"id":"https://openalex.org/I2801012209","display_name":"Albert B. Chandler Hospital","ror":"https://ror.org/03r8nx235","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285210727","https://openalex.org/I143302722","https://openalex.org/I2801012209"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"John M. Littleton","raw_affiliation_strings":["Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky; the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH); and the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky","the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH)","the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky; the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH); and the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I165862685","https://openalex.org/I2801012209"]},{"raw_affiliation_string":"Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH)","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I2801012209"]},{"raw_affiliation_string":"the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","institution_ids":["https://openalex.org/I1310053265","https://openalex.org/I165862685"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052509069","display_name":"Mark Prendergast","orcid":"https://orcid.org/0000-0002-1766-7421","observed_orcids":["https://orcid.org/0000-0002-1766-7421"]},"institutions":[{"id":"https://openalex.org/I1310053265","display_name":"St George's Hospital","ror":"https://ror.org/0001ke483","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1310053265","https://openalex.org/I2801196673"]},{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]},{"id":"https://openalex.org/I165862685","display_name":"St George's, University of London","ror":"https://ror.org/040f08y74","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I165862685","https://openalex.org/I4401726869"]},{"id":"https://openalex.org/I2801012209","display_name":"Albert B. Chandler Hospital","ror":"https://ror.org/03r8nx235","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285210727","https://openalex.org/I143302722","https://openalex.org/I2801012209"]}],"countries":["GB","US"],"is_corresponding":true,"raw_author_name":"Mark A. Prendergast","raw_affiliation_strings":["Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky; the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH); and the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky","the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH)","the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky; the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH); and the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I165862685","https://openalex.org/I2801012209"]},{"raw_affiliation_string":"Department of Psychology (PJM, RLS, MAP) and the Department of Pharmaceutical Sciences, College of Pharmacy (JML), University of Kentucky, Lexington, Kentucky","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"the Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, A.B. Chandler Medical Center, Lexington, Kentucky (BRH)","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I2801012209"]},{"raw_affiliation_string":"the Departments of Addictive Behavior and Pharmacology, St. George's Hospital Medical School, London, United Kingdom (HJL)","institution_ids":["https://openalex.org/I1310053265","https://openalex.org/I165862685"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5052509069"],"corresponding_institution_ids":["https://openalex.org/I1310053265","https://openalex.org/I143302722","https://openalex.org/I165862685","https://openalex.org/I2801012209"],"apc_list":{"value":4110,"currency":"USD","value_usd":4110},"apc_paid":null,"fwci":1.4007,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.73402062,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"29","issue":"5","first_page":"871","last_page":"881"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.42899999022483826,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.42899999022483826,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.25369998812675476,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.0608999989926815,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/corticosterone","display_name":"corticosterone","score":0.9929999709129333},{"id":"https://openalex.org/keywords/ethanol-withdrawal","display_name":"ethanol withdrawal","score":0.9769999980926514},{"id":"https://openalex.org/keywords/hippocampal-lesions","display_name":"hippocampal lesions","score":0.9409999847412109},{"id":"https://openalex.org/keywords/glucocorticoids","display_name":"glucocorticoids","score":0.9409999847412109},{"id":"https://openalex.org/keywords/alcoholism","display_name":"alcoholism","score":0.6830000281333923},{"id":"https://openalex.org/keywords/hippocampal-slice-cultures","display_name":"hippocampal slice cultures","score":0.8640000224113464},{"id":"https://openalex.org/keywords/ru486","display_name":"RU486","score":0.8289999961853027},{"id":"https://openalex.org/keywords/mk-801","display_name":"MK-801","score":0.9359999895095825},{"id":"https://openalex.org/keywords/spironolactone","display_name":"spironolactone","score":0.9950000047683716},{"id":"https://openalex.org/keywords/glucocorticoid-receptor","display_name":"glucocorticoid receptor","score":0.6869999766349792},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.4970000088214874}],"concepts":[{"id":"https://openalex.org/C2780352252","wikidata":"https://www.wikidata.org/wiki/Q422543","display_name":"Corticosterone","level":3,"score":0.8550023436546326},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.7212244272232056},{"id":"https://openalex.org/C98539663","wikidata":"https://www.wikidata.org/wiki/Q220599","display_name":"Cytosol","level":3,"score":0.6999883651733398},{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.6042933464050293},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.572611927986145},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5028178095817566},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4926477074623108},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4573068916797638},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3317807912826538},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2777392268180847},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.22372618317604065},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21131682395935059},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.05964386463165283},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000431","descriptor_name":"Ethanol","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000451","descriptor_name":"Mineralocorticoid Receptor Antagonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002492","descriptor_name":"Central Nervous System Depressants","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D003345","descriptor_name":"Corticosterone","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D003345","descriptor_name":"Corticosterone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003600","descriptor_name":"Cytosol","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003600","descriptor_name":"Cytosol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006727","descriptor_name":"Hormone Antagonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009924","descriptor_name":"Organ Culture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009930","descriptor_name":"Organic Chemicals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011419","descriptor_name":"Propidium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011965","descriptor_name":"Receptors, Glucocorticoid","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D013148","descriptor_name":"Spironolactone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013375","descriptor_name":"Substance Withdrawal Syndrome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013375","descriptor_name":"Substance Withdrawal Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D015735","descriptor_name":"Mifepristone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D016194","descriptor_name":"Receptors, N-Methyl-D-Aspartate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/01.alc.0000163509.27577.da","doi":"https://doi.org/10.1097/01.alc.0000163509.27577.da","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.alc.0000163509.27577.da","pdf_url":null,"source":{"id":"https://openalex.org/S115510430","display_name":"Alcoholism Clinical and Experimental Research","issn_l":"0145-6008","issn":["0145-6008","1530-0277","2993-7175"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcoholism: Clinical & Experimental Research","raw_type":"journal-article"},{"id":"pmid:15897733","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15897733","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcoholism, clinical and experimental research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8999999761581421}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7099999785423279}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4312703923","display_name":null,"funder_award_id":"AA014771","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G845976588","display_name":"Ethanol Withdrawal, Stress and Polyamine Neuroprotection","funder_award_id":"F31AA014771","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G977758278","display_name":null,"funder_award_id":"AA00274","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"}],"funders":[{"id":"https://openalex.org/F4320337330","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":91,"referenced_works":["https://openalex.org/W1502335233","https://openalex.org/W1550462067","https://openalex.org/W1560532813","https://openalex.org/W1902016348","https://openalex.org/W1967265097","https://openalex.org/W1967413223","https://openalex.org/W1973308205","https://openalex.org/W1974934586","https://openalex.org/W1975416249","https://openalex.org/W1978084060","https://openalex.org/W1979422799","https://openalex.org/W1979763846","https://openalex.org/W1980484933","https://openalex.org/W1984649085","https://openalex.org/W1984956928","https://openalex.org/W1988957190","https://openalex.org/W1989801390","https://openalex.org/W1993534198","https://openalex.org/W1994534741","https://openalex.org/W1994752541","https://openalex.org/W1994884839","https://openalex.org/W1994963087","https://openalex.org/W1995684466","https://openalex.org/W1996039145","https://openalex.org/W1999425979","https://openalex.org/W2003377853","https://openalex.org/W2004763425","https://openalex.org/W2007386764","https://openalex.org/W2010074472","https://openalex.org/W2014687481","https://openalex.org/W2019464314","https://openalex.org/W2020897240","https://openalex.org/W2021369749","https://openalex.org/W2022070327","https://openalex.org/W2025863425","https://openalex.org/W2025889980","https://openalex.org/W2026624785","https://openalex.org/W2026812475","https://openalex.org/W2027066838","https://openalex.org/W2027670108","https://openalex.org/W2029559183","https://openalex.org/W2036728836","https://openalex.org/W2037337146","https://openalex.org/W2039409343","https://openalex.org/W2040468089","https://openalex.org/W2041696588","https://openalex.org/W2048724759","https://openalex.org/W2048990637","https://openalex.org/W2053884303","https://openalex.org/W2053980736","https://openalex.org/W2056408203","https://openalex.org/W2057290193","https://openalex.org/W2060941369","https://openalex.org/W2061551125","https://openalex.org/W2062783907","https://openalex.org/W2066222900","https://openalex.org/W2073249470","https://openalex.org/W2073836271","https://openalex.org/W2076731330","https://openalex.org/W2078878556","https://openalex.org/W2079054696","https://openalex.org/W2087338522","https://openalex.org/W2090699562","https://openalex.org/W2097041318","https://openalex.org/W2097293665","https://openalex.org/W2099691833","https://openalex.org/W2101440381","https://openalex.org/W2116635659","https://openalex.org/W2122003111","https://openalex.org/W2125171586","https://openalex.org/W2127817146","https://openalex.org/W2128309917","https://openalex.org/W2134529460","https://openalex.org/W2136742966","https://openalex.org/W2142401762","https://openalex.org/W2150790263","https://openalex.org/W2159223986","https://openalex.org/W2165025521","https://openalex.org/W2165278596","https://openalex.org/W2171137970","https://openalex.org/W2171152000","https://openalex.org/W2297037381","https://openalex.org/W2334787351","https://openalex.org/W2402077285","https://openalex.org/W2416174547","https://openalex.org/W2460602301","https://openalex.org/W4246362673","https://openalex.org/W4256477906","https://openalex.org/W4301349939","https://openalex.org/W4302219957","https://openalex.org/W4322697794"],"related_works":["https://openalex.org/W2013236953","https://openalex.org/W1583092351","https://openalex.org/W2525757508","https://openalex.org/W1764488096","https://openalex.org/W1975416249","https://openalex.org/W1956210563","https://openalex.org/W1973308205","https://openalex.org/W2081647098","https://openalex.org/W7096466605","https://openalex.org/W2157040086"],"abstract_inverted_index":{"BACKGROUND:":[0],"Evidence":[1],"suggests":[2],"that":[3,25,45,207,238],"stress":[4],"hormones":[5],"(i.e.,":[6],"glucocorticoids)":[7],"may":[8,26,56],"be":[9],"increased":[10,46],"during":[11,19,111,118,137,180,210],"acute":[12],"or":[13,116,133,174],"chronic":[14],"consumption":[15],"of":[16,31,36,107,187,223,228,245],"ethanol":[17,22,52,70,112,138,181,190,211],"and":[18,54,74,82,95,114,126,151,162,196,226],"withdrawal":[20,55,115,144,191,214],"from":[21,234],"consumption,":[23],"effects":[24,186],"contribute":[27,240],"to":[28,41,67,124,241],"the":[29,37,43,89,229,242],"development":[30],"cognitive":[32],"impairment.":[33],"The":[34,232],"goal":[35],"current":[38],"studies":[39,236],"was":[40,178],"examine":[42],"hypothesis":[44],"glucocorticoid":[47,224],"levels":[48],"in":[49,158,163,169,216,248],"conjunction":[50],"with":[51,104],"exposure":[53,113,139,209],"cause":[57],"hippocampal":[58,62,218],"damage.":[59],"METHODS:":[60],"Organotypic":[61],"slice":[63],"cultures":[64,121,170],"were":[65,86,101,122,167,192],"exposed":[66,179],"50":[68],"mM":[69],"for":[71,76],"10":[72],"days":[73],"withdrawn":[75],"1":[77],"day.":[78],"After":[79],"withdrawal,":[80],"cytotoxicity":[81],"cytosolic":[83,152,164],"Ca2+":[84,153,165],"accumulation":[85,166],"measured":[87],"using":[88],"nucleic":[90],"acid":[91],"stain":[92],"propidium":[93,148,159],"iodide":[94,149,160],"Calcium":[96],"Orange,":[97],"AM,":[98],"respectively.":[99],"Cultures":[100],"also":[102],"treated":[103],"nontoxic":[105],"concentrations":[106],"corticosterone":[108,125,172,188,208],"(0.001-1":[109],"microM)":[110,136],"only":[117],"withdrawal.":[119,141,184],"Additional":[120],"coexposed":[123],"RU486":[127,195],"(0.1-10.0":[128,131],"microM),":[129,132],"spironolactone":[130,201],"MK-801":[134,197],"(20":[135],"and/or":[140,183,213],"RESULTS:":[142],"Ethanol":[143],"did":[145],"not":[146,199],"increase":[147],"fluorescence":[150,161],"levels.":[154],"However,":[155],"significant":[156,217],"increases":[157],"observed":[168],"when":[171],"(>":[173],"=":[175],"100":[176],"nM)":[177],"treatment":[182,212],"These":[185],"on":[189],"attenuated":[193],"by":[194,200],"but":[198],"coexposure.":[202],"CONCLUSIONS:":[203],"This":[204],"report":[205],"demonstrated":[206],"resulted":[215],"damage,":[219],"possibly":[220],"via":[221],"activation":[222],"receptors":[225],"enhancement":[227],"glutamatergic":[230],"cascade.":[231],"findings":[233],"these":[235],"suggest":[237],"glucocorticoids":[239],"neuropathological":[243],"consequences":[244],"alcohol":[246],"dependence":[247],"humans.":[249]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}