{"id":"https://openalex.org/W2019165625","doi":"https://doi.org/10.1016/0378-1119(94)90728-5","title":"The identification of a gene family in the Saccharomyces cerevisiae ergosterol biosynthesis pathway","display_name":"The identification of a gene family in the Saccharomyces cerevisiae ergosterol biosynthesis pathway","publication_year":1994,"publication_date":"1994-01-01","ids":{"openalex":"https://openalex.org/W2019165625","doi":"https://doi.org/10.1016/0378-1119(94)90728-5","mag":"2019165625","pmid":"https://pubmed.ncbi.nlm.nih.gov/8125337"},"language":"en","primary_location":{"id":"doi:10.1016/0378-1119(94)90728-5","doi":"https://doi.org/10.1016/0378-1119(94)90728-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0378-1119(94)90728-5","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103615864","display_name":"MARGARET H. LAI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Margaret H.Lai","raw_affiliation_strings":["Agricultural Research Division, and Medical Research Division, American Cyanamid, Princeton, NJ 08543-0400, USA","Agricultural Research Division, American Cyanamid, Princeton, NJ 08543-0400"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agricultural Research Division, and Medical Research Division, American Cyanamid, Princeton, NJ 08543-0400, USA","institution_ids":[]},{"raw_affiliation_string":"Agricultural Research Division, American Cyanamid, Princeton, NJ 08543-0400","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027241044","display_name":"Martin Bard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin Bard","raw_affiliation_strings":["Biology Department, Indiana University Purdue University at Indianapolis, 723 West Michigan Street, Indianapolis, IN 46202-5132. USA. Tel. (1-317) 274-0593, Fax (1-317) 274-2846"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, Indiana University Purdue University at Indianapolis, 723 West Michigan Street, Indianapolis, IN 46202-5132. USA. Tel. (1-317) 274-0593, Fax (1-317) 274-2846","institution_ids":["https://openalex.org/I55769427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074942907","display_name":"Charles A. Pierson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles A.Pierson","raw_affiliation_strings":["Biology Department, Indiana University Purdue University at Indianapolis, 723 West Michigan Street, Indianapolis, IN 46202-5132. USA. Tel. (1-317) 274-0593, Fax (1-317) 274-2846"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, Indiana University Purdue University at Indianapolis, 723 West Michigan Street, Indianapolis, IN 46202-5132. USA. Tel. (1-317) 274-0593, Fax (1-317) 274-2846","institution_ids":["https://openalex.org/I55769427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025967673","display_name":"John F.Alexander","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John F.Alexander","raw_affiliation_strings":["Biology Department, Indiana University Purdue University at Indianapolis, 723 West Michigan Street, Indianapolis, IN 46202-5132. USA. Tel. (1-317) 274-0593, Fax (1-317) 274-2846"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, Indiana University Purdue University at Indianapolis, 723 West Michigan Street, Indianapolis, IN 46202-5132. USA. Tel. (1-317) 274-0593, Fax (1-317) 274-2846","institution_ids":["https://openalex.org/I55769427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111761927","display_name":"Mark G. Goebl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Goebl","raw_affiliation_strings":["Department of Biochemisty and Molecular Biology, Indiana University Medical School, Van Nuys Medical Science Building, Indianapolis, IN 46202-5122, USA. Tel. (1-317) 274-2055, Fax (1-317) 274-4686"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemisty and Molecular Biology, Indiana University Medical School, Van Nuys Medical Science Building, Indianapolis, IN 46202-5122, USA. Tel. (1-317) 274-2055, Fax (1-317) 274-4686","institution_ids":["https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023059414","display_name":"Guy T. Carter","orcid":"https://orcid.org/0000-0002-9386-067X","observed_orcids":["https://orcid.org/0000-0002-9386-067X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guy T. Carter","raw_affiliation_strings":["Agricultural Research Division, and Medical Research Division, American Cyanamid, Princeton, NJ 08543-0400, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agricultural Research Division, and Medical Research Division, American Cyanamid, Princeton, NJ 08543-0400, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110386817","display_name":"Donald R. Kirsch","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Donald R. Kirsch","raw_affiliation_strings":["Agricultural Research Division, and Medical Research Division, American Cyanamid, Princeton, NJ 08543-0400, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agricultural Research Division, and Medical Research Division, American Cyanamid, Princeton, NJ 08543-0400, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5110386817"],"corresponding_institution_ids":[],"apc_list":{"value":3300,"currency":"USD","value_usd":3300},"apc_paid":null,"fwci":1.5925,"has_fulltext":false,"cited_by_count":67,"citation_normalized_percentile":{"value":0.83301373,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"140","issue":"1","first_page":"41","last_page":"49"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9409000277519226,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9409000277519226,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.022700000554323196,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13736","display_name":"Steroid Chemistry and Biochemistry","score":0.007300000172108412,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ergosterol-biosynthesis","display_name":"ergosterol biosynthesis","score":0.8600000143051147},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.8519999980926514},{"id":"https://openalex.org/keywords/insertional-mutagenesis","display_name":"insertional mutagenesis","score":0.7200000286102295},{"id":"https://openalex.org/keywords/erg2","display_name":"ERG2","score":0.6269999742507935},{"id":"https://openalex.org/keywords/gene-family-identification","display_name":"gene family identification","score":0.49300000071525574}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8954018354415894},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.7314740419387817},{"id":"https://openalex.org/C22744801","wikidata":"https://www.wikidata.org/wiki/Q172778","display_name":"Plasmid","level":3,"score":0.6925770044326782},{"id":"https://openalex.org/C2777910421","wikidata":"https://www.wikidata.org/wiki/Q143263","display_name":"Ergosterol","level":2,"score":0.6165410876274109},{"id":"https://openalex.org/C2779429346","wikidata":"https://www.wikidata.org/wiki/Q2236682","display_name":"Schizosaccharomyces pombe","level":4,"score":0.5331885814666748},{"id":"https://openalex.org/C2778718757","wikidata":"https://www.wikidata.org/wiki/Q143623","display_name":"Sterol","level":3,"score":0.5167219042778015},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4948713183403015},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.4442169964313507},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4395027756690979},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3700381815433502},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3211638331413269},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004271","descriptor_name":"DNA, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004351","descriptor_name":"Drug Resistance","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004875","descriptor_name":"Ergosterol","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D005800","descriptor_name":"Genes, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005810","descriptor_name":"Multigene Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009025","descriptor_name":"Morpholines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010088","descriptor_name":"Oxidoreductases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010088","descriptor_name":"Oxidoreductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012568","descriptor_name":"Schizosaccharomyces","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013251","descriptor_name":"Steroid Isomerases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013251","descriptor_name":"Steroid Isomerases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0378-1119(94)90728-5","doi":"https://doi.org/10.1016/0378-1119(94)90728-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0378-1119(94)90728-5","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},{"id":"pmid:8125337","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8125337","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W53557829","https://openalex.org/W1639259334","https://openalex.org/W1936218950","https://openalex.org/W1968916548","https://openalex.org/W1975304761","https://openalex.org/W1979991273","https://openalex.org/W2016445704","https://openalex.org/W2018168127","https://openalex.org/W2022014977","https://openalex.org/W2023078468","https://openalex.org/W2028015487","https://openalex.org/W2048422948","https://openalex.org/W2076570789","https://openalex.org/W2089949661","https://openalex.org/W2115073295","https://openalex.org/W2123264979","https://openalex.org/W2144029424","https://openalex.org/W2149308163","https://openalex.org/W2169333620","https://openalex.org/W6673078314"],"related_works":["https://openalex.org/W2022014977","https://openalex.org/W2016445704","https://openalex.org/W150564858","https://openalex.org/W1981820708","https://openalex.org/W2049281448","https://openalex.org/W2142289326","https://openalex.org/W1961393177","https://openalex.org/W4395464226","https://openalex.org/W181292515","https://openalex.org/W2028967650"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}