{"id":"https://openalex.org/W2019040943","doi":"https://doi.org/10.1016/0027-5107(95)00018-e","title":"Biological effect monitoring in industrial workers following incidental exposure to high concentrations of ethylene oxide","display_name":"Biological effect monitoring in industrial workers following incidental exposure to high concentrations of ethylene oxide","publication_year":1995,"publication_date":"1995-06-01","ids":{"openalex":"https://openalex.org/W2019040943","doi":"https://doi.org/10.1016/0027-5107(95)00018-e","mag":"2019040943","pmid":"https://pubmed.ncbi.nlm.nih.gov/7770077"},"language":"en","primary_location":{"id":"doi:10.1016/0027-5107(95)00018-e","doi":"https://doi.org/10.1016/0027-5107(95)00018-e","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0027-5107(95)00018-e","pdf_url":null,"source":{"id":"https://openalex.org/S4394735698","display_name":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","issn_l":"0027-5107","issn":["0027-5107","1386-1964","1873-135X","1879-2871"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038245959","display_name":"A.D. Tates","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"A.D. Tates","raw_affiliation_strings":["MGC Department of Radiation Genetics and Chemical Mutagenesis, Sylvius Laboratory, State University of Leiden, The Netherlands","MGC Department of Radiation Genetics and Chemical Mutagenesis, Sylvius Laboratory, State University of Leiden, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MGC Department of Radiation Genetics and Chemical Mutagenesis, Sylvius Laboratory, State University of Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]},{"raw_affiliation_string":"MGC Department of Radiation Genetics and Chemical Mutagenesis, Sylvius Laboratory, State University of Leiden, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011735913","display_name":"Peter J. Boogaard","orcid":"https://orcid.org/0000-0002-6964-6681","observed_orcids":["https://orcid.org/0000-0002-6964-6681"]},"institutions":[{"id":"https://openalex.org/I7923278","display_name":"Shell (Netherlands)","ror":"https://ror.org/00b5m4j81","country_code":"NL","type":"company","lineage":["https://openalex.org/I7923278"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"P.J. Boogaard","raw_affiliation_strings":["Shell Internationale Petroleum Maatschappij B.V., Health, Safety & Environment Division, P.O. Box 162, 2501 AN The Hague, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shell Internationale Petroleum Maatschappij B.V., Health, Safety & Environment Division, P.O. Box 162, 2501 AN The Hague, The Netherlands","institution_ids":["https://openalex.org/I7923278"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028330497","display_name":"F. Darroudi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"F. Darroudi","raw_affiliation_strings":["J.A. Cohen Institute, Interuniversity Research Institute for Radiopathology and Radiation Protection, Leiden, The Netherlands","MGC Department of Radiation Genetics and Chemical Mutagenesis, Sylvius Laboratory, State University of Leiden, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"J.A. Cohen Institute, Interuniversity Research Institute for Radiopathology and Radiation Protection, Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]},{"raw_affiliation_string":"MGC Department of Radiation Genetics and Chemical Mutagenesis, Sylvius Laboratory, State University of Leiden, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111862889","display_name":"Adyapalam T. Natarajan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"A.T. Natarajan","raw_affiliation_strings":["J.A. Cohen Institute, Interuniversity Research Institute for Radiopathology and Radiation Protection, Leiden, The Netherlands","MGC Department of Radiation Genetics and Chemical Mutagenesis, Sylvius Laboratory, State University of Leiden, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"J.A. Cohen Institute, Interuniversity Research Institute for Radiopathology and Radiation Protection, Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]},{"raw_affiliation_string":"MGC Department of Radiation Genetics and Chemical Mutagenesis, Sylvius Laboratory, State University of Leiden, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042378748","display_name":"M.E. Caubo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I7923278","display_name":"Shell (Netherlands)","ror":"https://ror.org/00b5m4j81","country_code":"NL","type":"company","lineage":["https://openalex.org/I7923278"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"M.E. Caubo","raw_affiliation_strings":["Shell Nederland Chemie B.V., Safety and Health Department, P.O. Box 3000, 3190 GA Hoogvliet-Rt, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shell Nederland Chemie B.V., Safety and Health Department, P.O. Box 3000, 3190 GA Hoogvliet-Rt, The Netherlands","institution_ids":["https://openalex.org/I7923278"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108519775","display_name":"N J van Sittert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210164678","display_name":"Shell (United Kingdom)","ror":"https://ror.org/05p330p21","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210164678","https://openalex.org/I7923278"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"N.J. van Sittert","raw_affiliation_strings":["Shell Research Ltd, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AG, UK","Shell Res. Ltd., Sittingbourne Res. Centre, Sittingbourne, Kent ME9 8AG, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shell Research Ltd, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AG, UK","institution_ids":["https://openalex.org/I4210164678"]},{"raw_affiliation_string":"Shell Res. Ltd., Sittingbourne Res. Centre, Sittingbourne, Kent ME9 8AG, UK","institution_ids":["https://openalex.org/I4210164678"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5038245959"],"corresponding_institution_ids":["https://openalex.org/I121797337"],"apc_list":{"value":3380,"currency":"USD","value_usd":3380},"apc_paid":null,"fwci":1.9088,"has_fulltext":false,"cited_by_count":56,"citation_normalized_percentile":{"value":0.86202071,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"329","issue":"1","first_page":"63","last_page":"77"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ethylene-oxide","display_name":"ethylene oxide","score":0.9990000128746033},{"id":"https://openalex.org/keywords/occupational-exposure","display_name":"occupational exposure","score":0.8920000195503235},{"id":"https://openalex.org/keywords/hemoglobin-adducts","display_name":"hemoglobin adducts","score":0.8690000176429749},{"id":"https://openalex.org/keywords/hprt-mutations","display_name":"HPRT mutations","score":0.7979999780654907},{"id":"https://openalex.org/keywords/micronuclei","display_name":"micronuclei","score":0.9779999852180481},{"id":"https://openalex.org/keywords/sister-chromatid-exchange","display_name":"sister chromatid exchange","score":0.9190000295639038},{"id":"https://openalex.org/keywords/lymphocytes","display_name":"lymphocytes","score":0.6439999938011169},{"id":"https://openalex.org/keywords/erythrocytes","display_name":"erythrocytes","score":0.968999981880188},{"id":"https://openalex.org/keywords/genotoxicity","display_name":"genotoxicity","score":0.7129999995231628},{"id":"https://openalex.org/keywords/chemical-industry-workers","display_name":"chemical industry workers","score":0.503000020980835},{"id":"https://openalex.org/keywords/biomonitoring","display_name":"biomonitoring","score":0.4790000021457672}],"concepts":[{"id":"https://openalex.org/C45080847","wikidata":"https://www.wikidata.org/wiki/Q1658004","display_name":"Micronucleus test","level":3,"score":0.8646035194396973},{"id":"https://openalex.org/C2777801237","wikidata":"https://www.wikidata.org/wiki/Q407473","display_name":"Ethylene oxide","level":4,"score":0.7287443280220032},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.6513336300849915},{"id":"https://openalex.org/C141710004","wikidata":"https://www.wikidata.org/wiki/Q744364","display_name":"Clastogen","level":4,"score":0.5656326413154602},{"id":"https://openalex.org/C2778959862","wikidata":"https://www.wikidata.org/wiki/Q1009245","display_name":"Genotoxicity","level":3,"score":0.5415722131729126},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.48724547028541565},{"id":"https://openalex.org/C36681516","wikidata":"https://www.wikidata.org/wiki/Q1700733","display_name":"Micronucleus","level":4,"score":0.4570986032485962},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.440425306558609},{"id":"https://openalex.org/C2987845665","wikidata":"https://www.wikidata.org/wiki/Q17072363","display_name":"Occupational exposure","level":2,"score":0.4177263081073761},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.3622233271598816},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3426707983016968},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3375425338745117},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31721389293670654},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3072296977043152},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.1102125346660614},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0},{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000062","descriptor_name":"Accidents, Occupational","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002617","descriptor_name":"Chemical Industry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004784","descriptor_name":"Environmental Monitoring","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005027","descriptor_name":"Ethylene Oxide","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D005027","descriptor_name":"Ethylene Oxide","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007041","descriptor_name":"Hypoxanthine Phosphoribosyltransferase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012854","descriptor_name":"Sister Chromatid Exchange","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014633","descriptor_name":"Valine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D014633","descriptor_name":"Valine","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016273","descriptor_name":"Occupational Exposure","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D018736","descriptor_name":"DNA Adducts","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D048629","descriptor_name":"Micronuclei, Chromosome-Defective","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0027-5107(95)00018-e","doi":"https://doi.org/10.1016/0027-5107(95)00018-e","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0027-5107(95)00018-e","pdf_url":null,"source":{"id":"https://openalex.org/S4394735698","display_name":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","issn_l":"0027-5107","issn":["0027-5107","1386-1964","1873-135X","1879-2871"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis","raw_type":"journal-article"},{"id":"pmid:7770077","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7770077","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1963634283","https://openalex.org/W1965711331","https://openalex.org/W1973296185","https://openalex.org/W1982256719","https://openalex.org/W1987346351","https://openalex.org/W1995195210","https://openalex.org/W2002976054","https://openalex.org/W2002994696","https://openalex.org/W2003278978","https://openalex.org/W2005529866","https://openalex.org/W2006984368","https://openalex.org/W2014977920","https://openalex.org/W2018841144","https://openalex.org/W2031665752","https://openalex.org/W2040859088","https://openalex.org/W2041045166","https://openalex.org/W2049289985","https://openalex.org/W2051121968","https://openalex.org/W2051796733","https://openalex.org/W2052748587","https://openalex.org/W2054256867","https://openalex.org/W2057354333","https://openalex.org/W2065414232","https://openalex.org/W2071546921","https://openalex.org/W2075180089","https://openalex.org/W2075891750","https://openalex.org/W2077203317","https://openalex.org/W2078766596","https://openalex.org/W2092251998","https://openalex.org/W2108277573","https://openalex.org/W2314433525","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W1982256719","https://openalex.org/W2086368351","https://openalex.org/W4237252191","https://openalex.org/W2314433525","https://openalex.org/W1968396343","https://openalex.org/W2005383794","https://openalex.org/W2125920089","https://openalex.org/W2077203317","https://openalex.org/W2075180089","https://openalex.org/W1967365304"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}