{"id":"https://openalex.org/W2019034729","doi":"https://doi.org/10.1002/ar.1092210312","title":"Electron microscopic cytochemical localization of Ca\u2010ATPase in the rod outer segments of the toadBufo marinus","display_name":"Electron microscopic cytochemical localization of Ca\u2010ATPase in the rod outer segments of the toadBufo marinus","publication_year":1988,"publication_date":"1988-07-01","ids":{"openalex":"https://openalex.org/W2019034729","doi":"https://doi.org/10.1002/ar.1092210312","mag":"2019034729","pmid":"https://pubmed.ncbi.nlm.nih.gov/2973264"},"language":"en","primary_location":{"id":"doi:10.1002/ar.1092210312","doi":"https://doi.org/10.1002/ar.1092210312","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ar.1092210312","pdf_url":null,"source":{"id":"https://openalex.org/S4210187571","display_name":"The Anatomical Record","issn_l":"0003-276X","issn":["0003-276X","1097-0185"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Anatomical Record","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5105467603","display_name":"Walter L. Davis","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Walter L. Davis","raw_affiliation_strings":["Department of Anatomy, Baylor College of Dentistry, Dallas, TX 75246","Department of Anatomy, Baylor College of Dentistry, Dallas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Baylor College of Dentistry, Dallas, TX 75246","institution_ids":[]},{"raw_affiliation_string":"Department of Anatomy, Baylor College of Dentistry, Dallas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110693670","display_name":"Herbert K. Hagler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094379","display_name":"University of Texas Health Science Center at Dallas","ror":"https://ror.org/00q16t150","country_code":"US","type":"education","lineage":["https://openalex.org/I4210094379"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. K. Hagler","raw_affiliation_strings":["Department of Pathology, The University of Texas Health Science Center, Dallas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The University of Texas Health Science Center, Dallas","institution_ids":["https://openalex.org/I4210094379"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056271398","display_name":"Gene R. Farmer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gene R. Farmer","raw_affiliation_strings":["Department of Anatomy, Baylor College of Dentistry, Dallas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Baylor College of Dentistry, Dallas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010984350","display_name":"James Martin","orcid":"https://orcid.org/0000-0002-9654-3864","observed_orcids":["https://orcid.org/0000-0002-9654-3864"]},"institutions":[{"id":"https://openalex.org/I2802366037","display_name":"Baylor University Medical Center","ror":"https://ror.org/03nxfhe13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802366037","https://openalex.org/I4210160418"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James H. Martin","raw_affiliation_strings":["Department of Pathology, Division of Electron Microscopy, Baylor University Medical Center, Dallas, Texas 75246"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Division of Electron Microscopy, Baylor University Medical Center, Dallas, Texas 75246","institution_ids":["https://openalex.org/I2802366037"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109572802","display_name":"George E. Bridges","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802366037","display_name":"Baylor University Medical Center","ror":"https://ror.org/03nxfhe13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802366037","https://openalex.org/I4210160418"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George Bridges","raw_affiliation_strings":["Department of Pathology, Division of Electron Microscopy, Baylor University Medical Center, Dallas, Texas 75246"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Division of Electron Microscopy, Baylor University Medical Center, Dallas, Texas 75246","institution_ids":["https://openalex.org/I2802366037"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5105467603"],"corresponding_institution_ids":[],"apc_list":{"value":4020,"currency":"USD","value_usd":4020},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.08470335,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"221","issue":"3","first_page":"761","last_page":"768"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.5282999873161316,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.5282999873161316,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12763","display_name":"ATP Synthase and ATPases Research","score":0.23240000009536743,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.06589999794960022,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ca2-atpase","display_name":"Ca2+-ATPase","score":0.796999990940094},{"id":"https://openalex.org/keywords/rod-outer-segments","display_name":"rod outer segments","score":0.9440000057220459},{"id":"https://openalex.org/keywords/rhinella-marina","display_name":"Rhinella marina","score":0.8230000138282776},{"id":"https://openalex.org/keywords/toad-retina","display_name":"toad retina","score":0.781000018119812},{"id":"https://openalex.org/keywords/ultrastructural-cytochemistry","display_name":"ultrastructural cytochemistry","score":0.765999972820282},{"id":"https://openalex.org/keywords/vanadate-inhibition","display_name":"vanadate inhibition","score":0.6899999976158142},{"id":"https://openalex.org/keywords/calcium-flux","display_name":"calcium flux","score":0.41499999165534973},{"id":"https://openalex.org/keywords/phototransduction","display_name":"phototransduction","score":0.9480000138282776},{"id":"https://openalex.org/keywords/cgmp","display_name":"cyclic GMP","score":0.7609999775886536}],"concepts":[{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.7389241456985474},{"id":"https://openalex.org/C2781116636","wikidata":"https://www.wikidata.org/wiki/Q426228","display_name":"Vanadate","level":2,"score":0.6723854541778564},{"id":"https://openalex.org/C23265538","wikidata":"https://www.wikidata.org/wiki/Q300033","display_name":"ATPase","level":3,"score":0.6585444211959839},{"id":"https://openalex.org/C2778166480","wikidata":"https://www.wikidata.org/wiki/Q6453151","display_name":"Toad","level":2,"score":0.6539304256439209},{"id":"https://openalex.org/C131667965","wikidata":"https://www.wikidata.org/wiki/Q445081","display_name":"Visual phototransduction","level":3,"score":0.6434664726257324},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.640633225440979},{"id":"https://openalex.org/C101571972","wikidata":"https://www.wikidata.org/wiki/Q3396061","display_name":"Calcium ATPase","level":4,"score":0.5306714177131653},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.49563515186309814},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.467663437128067},{"id":"https://openalex.org/C2777658833","wikidata":"https://www.wikidata.org/wiki/Q408437","display_name":"EGTA","level":3,"score":0.4576933979988098},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.45633620023727417},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.4541068971157074},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3590596914291382},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.32123661041259766},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.1684030294418335},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000252","descriptor_name":"Calcium-Transporting ATPases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002024","descriptor_name":"Bufo marinus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006651","descriptor_name":"Histocytochemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010786","descriptor_name":"Photoreceptor Cells","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D012374","descriptor_name":"Rod Cell Outer Segment","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/ar.1092210312","doi":"https://doi.org/10.1002/ar.1092210312","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ar.1092210312","pdf_url":null,"source":{"id":"https://openalex.org/S4210187571","display_name":"The Anatomical Record","issn_l":"0003-276X","issn":["0003-276X","1097-0185"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Anatomical Record","raw_type":"journal-article"},{"id":"pmid:2973264","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2973264","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Anatomical record","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"display_name":"Life below water","score":0.8199999928474426,"id":"https://metadata.un.org/sdg/14"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1135790426","https://openalex.org/W1219808221","https://openalex.org/W1966327186","https://openalex.org/W1971057798","https://openalex.org/W1974064985","https://openalex.org/W1985624709","https://openalex.org/W1997520290","https://openalex.org/W2005719745","https://openalex.org/W2022559498","https://openalex.org/W2022881355","https://openalex.org/W2024596007","https://openalex.org/W2025364863","https://openalex.org/W2029232890","https://openalex.org/W2032741875","https://openalex.org/W2037969105","https://openalex.org/W2045098775","https://openalex.org/W2051743902","https://openalex.org/W2054657337","https://openalex.org/W2059468094","https://openalex.org/W2066453053","https://openalex.org/W2075855004","https://openalex.org/W2077330062","https://openalex.org/W2080454286","https://openalex.org/W2080981029","https://openalex.org/W2081132774","https://openalex.org/W2091378485","https://openalex.org/W2097567710","https://openalex.org/W2102014024","https://openalex.org/W2105056427","https://openalex.org/W2105563311","https://openalex.org/W2109401564","https://openalex.org/W2113506485","https://openalex.org/W2129494930","https://openalex.org/W2146927479","https://openalex.org/W2153224229","https://openalex.org/W2158177029","https://openalex.org/W2321794570"],"related_works":["https://openalex.org/W1981040357","https://openalex.org/W2412770065","https://openalex.org/W1981151574","https://openalex.org/W2022324732","https://openalex.org/W2078180347","https://openalex.org/W1460413398","https://openalex.org/W2013513462","https://openalex.org/W2016505138","https://openalex.org/W2077497537","https://openalex.org/W2115951348"],"abstract_inverted_index":{"Transmission":[0],"electron":[1],"microscopy":[2,53],"and":[3,76,158],"ultracytochemistry":[4],"were":[5],"employed":[6],"in":[7,18,40,114,155,169],"an":[8,37,145],"attempt":[9],"to":[10,100,107,133],"localize":[11],"the":[12,19,25,41,45,50,55,64,70,91,109,117,135,142,156,161],"enzyme":[13],"calcium":[14,77,80,128,171],"adenosine":[15],"triphosphatase":[16],"(Ca-ATPase)":[17],"rod":[20,46,118],"outer":[21],"segments":[22],"(ROS)":[23],"of":[24,44,49,63,72,111,144,160],"toad":[26],"retina.":[27],"Utilizing":[28],"a":[29,112,167],"one-step":[30],"incubation":[31],"procedure,":[32],"Ca-ATPase":[33,102,147,164],"was":[34,67,93],"identified":[35,54],"as":[36,58],"electron-dense":[38],"precipitate":[39],"intradiskal":[42],"spaces":[43],"disks":[47],"(vesicles)":[48],"ROS.":[51],"Analytical":[52],"reaction":[56,65,92],"product":[57,66],"lead":[59],"phosphate.":[60],"The":[61,96],"formation":[62],"dependent":[68],"on":[69],"presence":[71,110,143],"ATP":[73],"(the":[74],"substrate)":[75],"ions.":[78,88],"However,":[79],"ions":[81],"could":[82],"be":[83,134],"substituted":[84],"for":[85,152],"by":[86],"magnesium":[87],"In":[89],"addition,":[90],"vanadate":[94],"sensitive.":[95],"latter":[97],"is":[98,130],"known":[99],"inhibit":[101],"activity.":[103],"Such":[104],"data":[105],"appear":[106],"indicate":[108,149],"Ca-Mg-ATPase":[113],"association":[115],"with":[116,140],"disks.":[119],"Since":[120],"cyclic":[121],"guanosine":[122],"monophosphate":[123],"(cyclic":[124],"GMP),":[125],"rather":[126],"than":[127],"ions,":[129],"currently":[131],"believed":[132],"primary":[136],"intracellular":[137,174],"messenger":[138],"associated":[139],"phototransduction,":[141],"ROS":[146],"may":[148],"other":[150],"functions":[151],"this":[153],"cation":[154],"physiology":[157],"biochemistry":[159],"visual":[162],"process.":[163],"might":[165],"play":[166],"role":[168],"directional":[170],"fluxes":[172],"between":[173],"compartments.":[175]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}