{"id":"https://openalex.org/W2018997599","doi":"https://doi.org/10.1007/s12640-009-9083-4","title":"Anthocyanins: Are They Beneficial in Treating Ethanol Neurotoxicity?","display_name":"Anthocyanins: Are They Beneficial in Treating Ethanol Neurotoxicity?","publication_year":2009,"publication_date":"2009-07-10","ids":{"openalex":"https://openalex.org/W2018997599","doi":"https://doi.org/10.1007/s12640-009-9083-4","mag":"2018997599","pmid":"https://pubmed.ncbi.nlm.nih.gov/19590929","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4992359"},"language":"en","primary_location":{"id":"doi:10.1007/s12640-009-9083-4","doi":"https://doi.org/10.1007/s12640-009-9083-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12640-009-9083-4","pdf_url":null,"source":{"id":"https://openalex.org/S95346388","display_name":"Neurotoxicity Research","issn_l":"1029-8428","issn":["1029-8428","1476-3524"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurotoxicity Research","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4992359","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100389245","display_name":"Gang Chen","orcid":"https://orcid.org/0000-0002-0839-8477","observed_orcids":["https://orcid.org/0000-0002-0839-8477"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gang Chen","raw_affiliation_strings":["Department of Internal Medicine, College of Medicine, University of Kentucky, 124C Combs Research Building, 800 Rose Street, Lexington, KY, 40536, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, College of Medicine, University of Kentucky, 124C Combs Research Building, 800 Rose Street, Lexington, KY, 40536, USA","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041424398","display_name":"Jia Luo","orcid":"https://orcid.org/0000-0002-6968-3618","observed_orcids":["https://orcid.org/0000-0002-6968-3618"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jia Luo","raw_affiliation_strings":["Department of Internal Medicine, College of Medicine, University of Kentucky, 124C Combs Research Building, 800 Rose Street, Lexington, KY, 40536, USA","Department of Internal Medicine, College of Medicine, University of Kentucky, Lexington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, College of Medicine, University of Kentucky, 124C Combs Research Building, 800 Rose Street, Lexington, KY, 40536, USA","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"Department of Internal Medicine, College of Medicine, University of Kentucky, Lexington, USA","institution_ids":["https://openalex.org/I143302722"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5041424398"],"corresponding_institution_ids":["https://openalex.org/I143302722"],"apc_list":{"value":4590,"currency":"USD","value_usd":4590},"apc_paid":null,"fwci":0.3566,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.3368984,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"17","issue":"1","first_page":"91","last_page":"101"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.4975999891757965,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.4975999891757965,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.35179999470710754,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.04960000142455101,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anthocyanins","display_name":"anthocyanins","score":1.0},{"id":"https://openalex.org/keywords/ethanol-neurotoxicity","display_name":"ethanol neurotoxicity","score":0.9950000047683716},{"id":"https://openalex.org/keywords/fetal-alcohol-spectrum-disorders","display_name":"fetal alcohol spectrum disorders","score":0.8460000157356262},{"id":"https://openalex.org/keywords/wernicke-korsakoff-syndrome","display_name":"Wernicke-Korsakoff syndrome","score":0.953000009059906},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9470000267028809},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.968999981880188},{"id":"https://openalex.org/keywords/antioxidants","display_name":"antioxidants","score":0.7149999737739563},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.9660000205039978},{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":0.949999988079071},{"id":"https://openalex.org/keywords/central-nervous-system-injury","display_name":"central nervous system injury","score":0.7979999780654907},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.7329999804496765}],"concepts":[{"id":"https://openalex.org/C2779491297","wikidata":"https://www.wikidata.org/wiki/Q3338704","display_name":"Neurotoxicity","level":3,"score":0.8955767154693604},{"id":"https://openalex.org/C25498285","wikidata":"https://www.wikidata.org/wiki/Q1981368","display_name":"Neuroprotection","level":2,"score":0.8871593475341797},{"id":"https://openalex.org/C2776925932","wikidata":"https://www.wikidata.org/wiki/Q1755122","display_name":"Neurodegeneration","level":3,"score":0.6800612211227417},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.6281282901763916},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4942927360534668},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.49040842056274414},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.35994529724121094},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.16512402892112732},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15816974639892578},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08026313781738281},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000872","descriptor_name":"Anthocyanins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000872","descriptor_name":"Anthocyanins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018696","descriptor_name":"Neuroprotective Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D018696","descriptor_name":"Neuroprotective Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020268","descriptor_name":"Alcohol-Induced Disorders, Nervous System","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D020268","descriptor_name":"Alcohol-Induced Disorders, Nervous System","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s12640-009-9083-4","doi":"https://doi.org/10.1007/s12640-009-9083-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12640-009-9083-4","pdf_url":null,"source":{"id":"https://openalex.org/S95346388","display_name":"Neurotoxicity Research","issn_l":"1029-8428","issn":["1029-8428","1476-3524"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurotoxicity Research","raw_type":"journal-article"},{"id":"pmid:19590929","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19590929","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurotoxicity research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4992359","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4992359","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Neurotox Res","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4992359","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4992359","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Neurotox Res","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.75,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1624698646","display_name":"ALCOHOL AND BREAST CANCER","funder_award_id":"R01AA017226","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G2572184644","display_name":"Endoplasmic Reticulum Stress and Alcohol Neurotoxicity","funder_award_id":"2r01aa015407-18a1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2978868897","display_name":null,"funder_award_id":"R01\u00a0AA015407","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G4687033681","display_name":null,"funder_award_id":"AA017226","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G7633784009","display_name":null,"funder_award_id":"AA015407","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337330","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":138,"referenced_works":["https://openalex.org/W15555732","https://openalex.org/W161495139","https://openalex.org/W1559948142","https://openalex.org/W1571882050","https://openalex.org/W1593073476","https://openalex.org/W1761641134","https://openalex.org/W1824652155","https://openalex.org/W1913359277","https://openalex.org/W1943403340","https://openalex.org/W1964184380","https://openalex.org/W1964209473","https://openalex.org/W1964900343","https://openalex.org/W1965109985","https://openalex.org/W1965279522","https://openalex.org/W1966069793","https://openalex.org/W1966259921","https://openalex.org/W1968203886","https://openalex.org/W1969080189","https://openalex.org/W1969570348","https://openalex.org/W1971125122","https://openalex.org/W1972254930","https://openalex.org/W1973545940","https://openalex.org/W1975024858","https://openalex.org/W1975482838","https://openalex.org/W1978168284","https://openalex.org/W1978794982","https://openalex.org/W1978870143","https://openalex.org/W1981145469","https://openalex.org/W1983254586","https://openalex.org/W1986366688","https://openalex.org/W1986527680","https://openalex.org/W1986823644","https://openalex.org/W1990413063","https://openalex.org/W1992551825","https://openalex.org/W1997558636","https://openalex.org/W1998668705","https://openalex.org/W2000446726","https://openalex.org/W2001491797","https://openalex.org/W2001898490","https://openalex.org/W2003243446","https://openalex.org/W2003573918","https://openalex.org/W2007253341","https://openalex.org/W2008266059","https://openalex.org/W2008718748","https://openalex.org/W2008857963","https://openalex.org/W2011500919","https://openalex.org/W2012543776","https://openalex.org/W2013310688","https://openalex.org/W2013424862","https://openalex.org/W2014721575","https://openalex.org/W2015048300","https://openalex.org/W2015371978","https://openalex.org/W2016737310","https://openalex.org/W2020785892","https://openalex.org/W2021635663","https://openalex.org/W2025447502","https://openalex.org/W2025770918","https://openalex.org/W2027605059","https://openalex.org/W2031650968","https://openalex.org/W2033138548","https://openalex.org/W2033815837","https://openalex.org/W2034003832","https://openalex.org/W2037342598","https://openalex.org/W2037939062","https://openalex.org/W2038430170","https://openalex.org/W2038916833","https://openalex.org/W2039252406","https://openalex.org/W2039847447","https://openalex.org/W2044873096","https://openalex.org/W2046505051","https://openalex.org/W2047291208","https://openalex.org/W2049365848","https://openalex.org/W2050781125","https://openalex.org/W2055339187","https://openalex.org/W2056401376","https://openalex.org/W2058130980","https://openalex.org/W2058714774","https://openalex.org/W2059426523","https://openalex.org/W2060210126","https://openalex.org/W2060734495","https://openalex.org/W2062904391","https://openalex.org/W2064714515","https://openalex.org/W2066637529","https://openalex.org/W2068954221","https://openalex.org/W2073003808","https://openalex.org/W2078576748","https://openalex.org/W2080603926","https://openalex.org/W2084396890","https://openalex.org/W2084632170","https://openalex.org/W2085926435","https://openalex.org/W2086233383","https://openalex.org/W2086562792","https://openalex.org/W2088134976","https://openalex.org/W2091851381","https://openalex.org/W2093417625","https://openalex.org/W2095320612","https://openalex.org/W2095370074","https://openalex.org/W2097912983","https://openalex.org/W2098349554","https://openalex.org/W2098798885","https://openalex.org/W2099129745","https://openalex.org/W2099295724","https://openalex.org/W2100998391","https://openalex.org/W2101072227","https://openalex.org/W2105234557","https://openalex.org/W2111335747","https://openalex.org/W2112862665","https://openalex.org/W2113174175","https://openalex.org/W2115992472","https://openalex.org/W2117169929","https://openalex.org/W2118447955","https://openalex.org/W2120730389","https://openalex.org/W2123985223","https://openalex.org/W2126804189","https://openalex.org/W2129971112","https://openalex.org/W2134565629","https://openalex.org/W2135287265","https://openalex.org/W2138076366","https://openalex.org/W2138954300","https://openalex.org/W2141225790","https://openalex.org/W2142017368","https://openalex.org/W2144821195","https://openalex.org/W2148274266","https://openalex.org/W2149044585","https://openalex.org/W2149045062","https://openalex.org/W2150647068","https://openalex.org/W2153408289","https://openalex.org/W2153906602","https://openalex.org/W2154801407","https://openalex.org/W2159874325","https://openalex.org/W2161055036","https://openalex.org/W2161090119","https://openalex.org/W2166346862","https://openalex.org/W2168712965","https://openalex.org/W2275293999","https://openalex.org/W2331426073","https://openalex.org/W2402268584","https://openalex.org/W2443867772"],"related_works":["https://openalex.org/W2084439088","https://openalex.org/W2171921348","https://openalex.org/W2111816207","https://openalex.org/W2013146071","https://openalex.org/W1971125122","https://openalex.org/W1524969584","https://openalex.org/W1969048004","https://openalex.org/W2050781125","https://openalex.org/W2131153615","https://openalex.org/W2996335119"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":6}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}