{"id":"https://openalex.org/W2018988752","doi":"https://doi.org/10.1016/j.jconrel.2015.01.039","title":"Macrophage mediated biomimetic delivery system for the treatment of lung metastasis of breast cancer","display_name":"Macrophage mediated biomimetic delivery system for the treatment of lung metastasis of breast cancer","publication_year":2015,"publication_date":"2015-01-31","ids":{"openalex":"https://openalex.org/W2018988752","doi":"https://doi.org/10.1016/j.jconrel.2015.01.039","mag":"2018988752","pmid":"https://pubmed.ncbi.nlm.nih.gov/25646783"},"language":"en","primary_location":{"id":"doi:10.1016/j.jconrel.2015.01.039","doi":"https://doi.org/10.1016/j.jconrel.2015.01.039","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jconrel.2015.01.039","pdf_url":null,"source":{"id":"https://openalex.org/S161954266","display_name":"Journal of Controlled Release","issn_l":"0168-3659","issn":["0168-3659","1873-4995"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Controlled Release","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030345640","display_name":"Jijun Fu","orcid":"https://orcid.org/0000-0001-7702-5140","observed_orcids":["https://orcid.org/0000-0001-7702-5140"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4391768132","display_name":"State Key Laboratory of Natural and Biomimetic Drugs","ror":"https://ror.org/049mqh532","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jijun Fu","raw_affiliation_strings":["State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100709844","display_name":"Dan Wang","orcid":"https://orcid.org/0000-0001-9079-2360","observed_orcids":["https://orcid.org/0000-0001-9079-2360"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4391768132","display_name":"State Key Laboratory of Natural and Biomimetic Drugs","ror":"https://ror.org/049mqh532","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dan Wang","raw_affiliation_strings":["State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112316719","display_name":"Dong Mei","orcid":"https://orcid.org/0000-0002-0801-8702","observed_orcids":["https://orcid.org/0000-0002-0801-8702"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4391768132","display_name":"State Key Laboratory of Natural and Biomimetic Drugs","ror":"https://ror.org/049mqh532","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dong Mei","raw_affiliation_strings":["State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101413103","display_name":"Haoran Zhang","orcid":"https://orcid.org/0009-0009-9260-6838","observed_orcids":["https://orcid.org/0009-0009-9260-6838","https://orcid.org/0000-0002-9731-8909"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4391768132","display_name":"State Key Laboratory of Natural and Biomimetic Drugs","ror":"https://ror.org/049mqh532","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haoran Zhang","raw_affiliation_strings":["State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100356529","display_name":"Zhao\u2010Yang Wang","orcid":"https://orcid.org/0000-0002-2391-5938","observed_orcids":["https://orcid.org/0000-0002-2391-5938"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4391768132","display_name":"State Key Laboratory of Natural and Biomimetic Drugs","ror":"https://ror.org/049mqh532","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhaoyang Wang","raw_affiliation_strings":["State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100654849","display_name":"Bing He","orcid":"https://orcid.org/0000-0001-5304-5251","observed_orcids":["https://orcid.org/0000-0001-5304-5251"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4391768132","display_name":"State Key Laboratory of Natural and Biomimetic Drugs","ror":"https://ror.org/049mqh532","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bing He","raw_affiliation_strings":["State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043866674","display_name":"Wenbing Dai","orcid":"https://orcid.org/0000-0002-4114-4022","observed_orcids":["https://orcid.org/0000-0002-4114-4022"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4391768132","display_name":"State Key Laboratory of Natural and Biomimetic Drugs","ror":"https://ror.org/049mqh532","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenbing Dai","raw_affiliation_strings":["State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100408669","display_name":"Hua Zhang","orcid":"https://orcid.org/0000-0001-9518-740X","observed_orcids":["https://orcid.org/0000-0001-9518-740X","https://orcid.org/0000-0001-5349-505X","https://orcid.org/0009-0006-0636-4499","https://orcid.org/0000-0001-5853-8928","https://orcid.org/0000-0001-9112-7397"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4391768132","display_name":"State Key Laboratory of Natural and Biomimetic Drugs","ror":"https://ror.org/049mqh532","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hua Zhang","raw_affiliation_strings":["State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100761084","display_name":"Xueqing Wang","orcid":"https://orcid.org/0000-0003-4732-630X","observed_orcids":["https://orcid.org/0000-0003-4732-630X"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4391768132","display_name":"State Key Laboratory of Natural and Biomimetic Drugs","ror":"https://ror.org/049mqh532","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xueqing Wang","raw_affiliation_strings":["State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100381953","display_name":"Qiang Zhang","orcid":"https://orcid.org/0000-0002-8862-3098","observed_orcids":["https://orcid.org/0000-0002-8862-3098"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4391768132","display_name":"State Key Laboratory of Natural and Biomimetic Drugs","ror":"https://ror.org/049mqh532","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qiang Zhang","raw_affiliation_strings":["State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. Electronic address: zqdodo@bjmu.edu.cn","\u2021State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. Electronic address: zqdodo@bjmu.edu.cn","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]},{"raw_affiliation_string":"\u2021State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100381953"],"corresponding_institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768132"],"apc_list":{"value":4440,"currency":"USD","value_usd":4440},"apc_paid":null,"fwci":3.2545,"has_fulltext":false,"cited_by_count":139,"citation_normalized_percentile":{"value":0.93164386,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"204","issue":null,"first_page":"11","last_page":"19"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.8657000064849854,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.8657000064849854,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12996","display_name":"Bacterial Cancer Therapy","score":0.0706000030040741,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.03970000147819519,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/doxorubicin","display_name":"doxorubicin","score":0.7540000081062317},{"id":"https://openalex.org/keywords/breast-cancer-lung-metastasis","display_name":"breast cancer lung metastasis","score":0.8939999938011169},{"id":"https://openalex.org/keywords/tumor-homing","display_name":"tumor homing","score":0.8360000252723694},{"id":"https://openalex.org/keywords/4t1-cells","display_name":"4T1 cells","score":0.8130000233650208},{"id":"https://openalex.org/keywords/targeted-cancer-therapy","display_name":"targeted cancer therapy","score":0.7960000038146973},{"id":"https://openalex.org/keywords/drug-loading-and-release","display_name":"drug loading and release","score":0.5740000009536743}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6287233233451843},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.6056122779846191},{"id":"https://openalex.org/C2781303535","wikidata":"https://www.wikidata.org/wiki/Q18936","display_name":"Doxorubicin","level":3,"score":0.6034855246543884},{"id":"https://openalex.org/C151872237","wikidata":"https://www.wikidata.org/wiki/Q1410759","display_name":"Homing (biology)","level":2,"score":0.5947077870368958},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.5676862001419067},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.559075653553009},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.557726263999939},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.5448009371757507},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.44899505376815796},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.4421151876449585},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.43920278549194336},{"id":"https://openalex.org/C2775930923","wikidata":"https://www.wikidata.org/wiki/Q12859063","display_name":"Metastatic breast cancer","level":4,"score":0.4217206537723541},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3932334780693054},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3903249204158783},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37185361981391907},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33765724301338196},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2682100534439087},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.23469430208206177},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1655406653881073},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.12982973456382751},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.05594140291213989},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000903","descriptor_name":"Antibiotics, Antineoplastic","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000903","descriptor_name":"Antibiotics, Antineoplastic","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002453","descriptor_name":"Cell Cycle","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004317","descriptor_name":"Doxorubicin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D004317","descriptor_name":"Doxorubicin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008325","descriptor_name":"Mammary Neoplasms, Experimental","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008325","descriptor_name":"Mammary Neoplasms, Experimental","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016503","descriptor_name":"Drug Delivery Systems","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D018929","descriptor_name":"Cell Culture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032701","descriptor_name":"Biomimetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065546","descriptor_name":"Drug Liberation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jconrel.2015.01.039","doi":"https://doi.org/10.1016/j.jconrel.2015.01.039","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jconrel.2015.01.039","pdf_url":null,"source":{"id":"https://openalex.org/S161954266","display_name":"Journal of Controlled Release","issn_l":"0168-3659","issn":["0168-3659","1873-4995"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Controlled Release","raw_type":"journal-article"},{"id":"pmid:25646783","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25646783","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of controlled release : official journal of the Controlled Release Society","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4815166686","display_name":null,"funder_award_id":"BMU20110263","funder_id":"https://openalex.org/F4320321106","funder_display_name":"Ministry of Education of the People's Republic of China"},{"id":"https://openalex.org/G6333215799","display_name":"\u57fa\u4e8e\u5206\u5b50\u9776\u5411\u7ed9\u836f\u7684\u80bf\u7624\u8054\u5408\u6cbb\u7597","funder_award_id":"81130059","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321106","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1927732700","https://openalex.org/W1968820334","https://openalex.org/W2000534793","https://openalex.org/W2004424104","https://openalex.org/W2005159406","https://openalex.org/W2015591824","https://openalex.org/W2026344055","https://openalex.org/W2026571103","https://openalex.org/W2027925515","https://openalex.org/W2035433060","https://openalex.org/W2040294604","https://openalex.org/W2041454553","https://openalex.org/W2042018154","https://openalex.org/W2046634775","https://openalex.org/W2056175833","https://openalex.org/W2059488077","https://openalex.org/W2065710500","https://openalex.org/W2077737321","https://openalex.org/W2078147660","https://openalex.org/W2078696346","https://openalex.org/W2083261882","https://openalex.org/W2089945820","https://openalex.org/W2115583652","https://openalex.org/W2121634364","https://openalex.org/W2122071242","https://openalex.org/W2122516856","https://openalex.org/W2125793635","https://openalex.org/W2125865280","https://openalex.org/W2131430454","https://openalex.org/W2159066312","https://openalex.org/W2601119316"],"related_works":["https://openalex.org/W2041401460","https://openalex.org/W4309437990","https://openalex.org/W4388633638","https://openalex.org/W4384819175","https://openalex.org/W4397002211","https://openalex.org/W4416023769","https://openalex.org/W2903378987","https://openalex.org/W2478711226","https://openalex.org/W3110885349","https://openalex.org/W2990134991"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":17},{"year":2020,"cited_by_count":17},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}