{"id":"https://openalex.org/W2018756967","doi":"https://doi.org/10.1212/wnl.47.3.813","title":"Prospective evaluation of MRI lumbosacral nerve root enhancement in acute Guillain-Barre syndrome","display_name":"Prospective evaluation of MRI lumbosacral nerve root enhancement in acute Guillain-Barre syndrome","publication_year":1996,"publication_date":"1996-09-01","ids":{"openalex":"https://openalex.org/W2018756967","doi":"https://doi.org/10.1212/wnl.47.3.813","mag":"2018756967","pmid":"https://pubmed.ncbi.nlm.nih.gov/8797486"},"language":"en","primary_location":{"id":"doi:10.1212/wnl.47.3.813","doi":"https://doi.org/10.1212/wnl.47.3.813","is_oa":false,"landing_page_url":"https://doi.org/10.1212/wnl.47.3.813","pdf_url":null,"source":{"id":"https://openalex.org/S79704628","display_name":"Neurology","issn_l":"0028-3878","issn":["0028-3878","1526-632X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109264449","display_name":"Kenneth C. Gorson","orcid":"https://orcid.org/0000-0003-4955-1324","observed_orcids":["https://orcid.org/0000-0003-4955-1324"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I3018163063","display_name":"St. Elizabeth's Medical Center","ror":"https://ror.org/00cr15z55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3018163063"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth C. Gorson","raw_affiliation_strings":["Department of Medicine, St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA 02135, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA 02135, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I3018163063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109951126","display_name":"Allan H. Ropper","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Allan H. Ropper","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045309757","display_name":"Mary Anne Muriello","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mary Anne Muriello","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5034218936","display_name":"Richard Blair","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard Blair","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.287,"has_fulltext":false,"cited_by_count":166,"citation_normalized_percentile":{"value":0.8739152,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"47","issue":"3","first_page":"813","last_page":"817"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11735","display_name":"Peripheral Neuropathies and Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11735","display_name":"Peripheral Neuropathies and Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10954","display_name":"Peripheral Nerve Disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12331","display_name":"Hereditary Neurological Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/guillain-barre-syndrome","display_name":"Guillain-Barr\u00e9 syndrome","score":0.9380000233650208},{"id":"https://openalex.org/keywords/cauda-equina","display_name":"cauda equina","score":0.8080000281333923},{"id":"https://openalex.org/keywords/nerve-root-enhancement","display_name":"nerve root enhancement","score":0.9449999928474426},{"id":"https://openalex.org/keywords/gadolinium-enhanced-mri","display_name":"gadolinium-enhanced MRI","score":0.9269999861717224},{"id":"https://openalex.org/keywords/lumbosacral-spine","display_name":"lumbosacral spine","score":0.8960000276565552},{"id":"https://openalex.org/keywords/diagnostic-sensitivity","display_name":"diagnostic sensitivity","score":0.5950000286102295},{"id":"https://openalex.org/keywords/back-and-leg-pain","display_name":"back and leg pain","score":0.7160000205039978},{"id":"https://openalex.org/keywords/disability-grade","display_name":"disability grade","score":0.871999979019165},{"id":"https://openalex.org/keywords/recovery-time","display_name":"recovery time","score":0.5640000104904175},{"id":"https://openalex.org/keywords/cerebrospinal-fluid-protein","display_name":"cerebrospinal fluid protein","score":0.6050000190734863},{"id":"https://openalex.org/keywords/electromyography","display_name":"electromyography","score":0.7139999866485596}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8783994317054749},{"id":"https://openalex.org/C178409289","wikidata":"https://www.wikidata.org/wiki/Q674696","display_name":"Nerve root","level":2,"score":0.858111560344696},{"id":"https://openalex.org/C2781300204","wikidata":"https://www.wikidata.org/wiki/Q1051445","display_name":"Cauda equina","level":3,"score":0.8528966307640076},{"id":"https://openalex.org/C7146039","wikidata":"https://www.wikidata.org/wiki/Q3624375","display_name":"Lumbosacral joint","level":2,"score":0.809051513671875},{"id":"https://openalex.org/C2780536975","wikidata":"https://www.wikidata.org/wiki/Q1051436","display_name":"Cauda equina syndrome","level":2,"score":0.5940345525741577},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3362576365470886},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3195542097091675},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.2073996663093567},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008161","descriptor_name":"Lumbosacral Region","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011129","descriptor_name":"Polyradiculoneuropathy","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013126","descriptor_name":"Spinal Nerve Roots","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1212/wnl.47.3.813","doi":"https://doi.org/10.1212/wnl.47.3.813","is_oa":false,"landing_page_url":"https://doi.org/10.1212/wnl.47.3.813","pdf_url":null,"source":{"id":"https://openalex.org/S79704628","display_name":"Neurology","issn_l":"0028-3878","issn":["0028-3878","1526-632X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurology","raw_type":"journal-article"},{"id":"pmid:8797486","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8797486","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1970238430","https://openalex.org/W1977626530","https://openalex.org/W1986051663","https://openalex.org/W2011260009","https://openalex.org/W2017900694","https://openalex.org/W2045147557","https://openalex.org/W2057258055","https://openalex.org/W2064309062","https://openalex.org/W2148621330","https://openalex.org/W2153271725","https://openalex.org/W2163550872","https://openalex.org/W2414262416","https://openalex.org/W2418453589","https://openalex.org/W4230531881","https://openalex.org/W4321318941"],"related_works":["https://openalex.org/W2474360783","https://openalex.org/W272391837","https://openalex.org/W2890038086","https://openalex.org/W3121894484","https://openalex.org/W2045770051","https://openalex.org/W2050297933","https://openalex.org/W2018432213","https://openalex.org/W2069252660","https://openalex.org/W2092701542","https://openalex.org/W1978390253"],"abstract_inverted_index":{"Nerve":[0],"root":[1,42,73,147,161,222,269],"enhancement":[2,43,107,148,162,223,270],"of":[3,19,58,66,85,95,103,118,166,172,177,230,244,252,279],"the":[4,13,164,167,186,199,231],"cauda":[5,70,232],"equina":[6,71,233],"occurs":[7],"in":[8,31,78,82,114,135,250],"Guillain-Barr\u00e9":[9],"syndrome":[10],"(GBS),":[11],"but":[12,217],"frequency,":[14],"diagnostic":[15],"value,":[16],"and":[17,38,80,140,163,203,214,224,247,277],"meaning":[18],"this":[20],"finding":[21,256],"is":[22,241],"unknown.":[23],"We":[24],"prospectively":[25],"obtained":[26,52],"gadolinium-enhanced":[27],"lumbosacral":[28,239],"spine":[29],"MRIs":[30,50],"24":[32,67],"consecutive":[33],"patients":[34,68,104,119,136,143,190],"with":[35,87,93,97,105,120,137,144,236,272],"acute":[36,245],"GBS":[37,89,126,246,274],"blindly":[39],"rated":[40],"nerve":[41,72,146,160,221,234,268],"as":[44],"absent,":[45],"mild,":[46],"or":[47,111,122,185],"prominent.":[48],"The":[49,125],"were":[51,207,219],"13":[53],"days,":[54,205],"mean,":[55],"after":[56],"onset":[57],"symptoms":[59],"(range":[60],"2":[61,94,153,183],"to":[62,116,130,191,193],"42":[63],"days).":[64],"Twenty":[65],"had":[69,90,108],"enhancement,":[74,91,139],"which":[75],"was":[76,133,156,248],"mild":[77,121],"6":[79],"prominent":[81,106,138,145,220],"14.":[83],"Eighteen":[84],"19":[86],"\"typical\"":[88],"compared":[92],"5":[96,131],"a":[98],"variant":[99],"presentation.":[100],"Sixty":[101],"percent":[102],"severe":[109],"back":[110],"leg":[112],"pain":[113],"contrast":[115],"10%":[117],"no":[123,157],"enhancement.":[124],"disability":[127,180,275],"grade":[128,181,194],"(0":[129],"scale)":[132],"higher":[134],"significantly":[141],"fewer":[142],"could":[149],"walk":[150],"independently":[151],"by":[152],"months.":[154],"There":[155],"relationship":[158],"between":[159],"timing":[165],"MRI,":[168],"CSF":[169,227],"protein,":[170],"any":[171],"several":[173],"EMG":[174],"abnormalities,":[175],"duration":[176,278],"hospitalization,":[178],"mean":[179],"at":[182,201],"months,":[184],"time":[187],"required":[188],"for":[189,210],"improve":[192],"2.":[195],"In":[196,265],"two":[197],"patients,":[198],"EMGs":[200],"11":[202],"20":[204],"respectively,":[206],"normal":[208],"except":[209],"slightly":[211],"prolonged":[212],"F-responses":[213],"neurogenic":[215],"recruitment,":[216],"there":[218],"an":[225],"elevated":[226],"protein.":[228],"Enhancement":[229],"roots":[235],"gadolinium":[237],"on":[238],"MRI":[240],"83%":[242],"sensitive":[243],"present":[249],"95%":[251],"typical":[253],"cases.":[254],"This":[255],"may":[257],"be":[258],"useful":[259],"when":[260],"electrophysiologic":[261],"abnormalities":[262],"are":[263],"equivocal.":[264],"addition,":[266],"conspicuous":[267],"correlates":[271],"pain,":[273],"grade,":[276],"recovery.":[280]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}