{"id":"https://openalex.org/W2018708785","doi":"https://doi.org/10.1529/biophysj.104.048074","title":"Nanoscale Features of Fibronectin Fibrillogenesis Depend on Protein-Substrate Interaction and Cytoskeleton Structure","display_name":"Nanoscale Features of Fibronectin Fibrillogenesis Depend on Protein-Substrate Interaction and Cytoskeleton Structure","publication_year":2004,"publication_date":"2004-11-08","ids":{"openalex":"https://openalex.org/W2018708785","doi":"https://doi.org/10.1529/biophysj.104.048074","mag":"2018708785","pmid":"https://pubmed.ncbi.nlm.nih.gov/15533920","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1305030"},"language":"en","primary_location":{"id":"doi:10.1529/biophysj.104.048074","doi":"https://doi.org/10.1529/biophysj.104.048074","is_oa":true,"landing_page_url":"https://doi.org/10.1529/biophysj.104.048074","pdf_url":null,"source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1529/biophysj.104.048074","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002901309","display_name":"W. Pompe","orcid":"https://orcid.org/0000-0003-1508-4959","observed_orcids":["https://orcid.org/0000-0003-1508-4959"]},"institutions":[{"id":"https://openalex.org/I4210107560","display_name":"Max Bergmann Center of Biomaterials","ror":"https://ror.org/01t4pzq33","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I4210107560","https://openalex.org/I4210111834","https://openalex.org/I78650965"]},{"id":"https://openalex.org/I4210111834","display_name":"Leibniz Institute of Polymer Research","ror":"https://ror.org/01tspta37","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I4210111834"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Tilo Pompe","raw_affiliation_strings":["Institute of Polymer Research Dresden and Max Bergmann Center of Biomaterials Dresden, 01069 Dresden, Germany. pompe-tilo@ipfdd.de","Institute of Polymer Research Dresden and Max Bergmann Center of Biomaterials Dresden, 01069 Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Polymer Research Dresden and Max Bergmann Center of Biomaterials Dresden, 01069 Dresden, Germany. pompe-tilo@ipfdd.de","institution_ids":["https://openalex.org/I4210107560","https://openalex.org/I4210111834"]},{"raw_affiliation_string":"Institute of Polymer Research Dresden and Max Bergmann Center of Biomaterials Dresden, 01069 Dresden, Germany","institution_ids":["https://openalex.org/I4210107560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033695150","display_name":"Lars David Renner","orcid":"https://orcid.org/0000-0003-0178-1788","observed_orcids":["https://orcid.org/0000-0003-0178-1788"]},"institutions":[{"id":"https://openalex.org/I4210107560","display_name":"Max Bergmann Center of Biomaterials","ror":"https://ror.org/01t4pzq33","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I4210107560","https://openalex.org/I4210111834","https://openalex.org/I78650965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Lars Renner","raw_affiliation_strings":["Institute of Polymer Research Dresden and Max Bergmann Center of Biomaterials Dresden, 01069 Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Polymer Research Dresden and Max Bergmann Center of Biomaterials Dresden, 01069 Dresden, Germany","institution_ids":["https://openalex.org/I4210107560"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015920322","display_name":"Carsten Werner","orcid":"https://orcid.org/0000-0003-0189-3448","observed_orcids":["https://orcid.org/0000-0003-0189-3448"]},"institutions":[{"id":"https://openalex.org/I4210107560","display_name":"Max Bergmann Center of Biomaterials","ror":"https://ror.org/01t4pzq33","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I4210107560","https://openalex.org/I4210111834","https://openalex.org/I78650965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Carsten Werner","raw_affiliation_strings":["Institute of Polymer Research Dresden and Max Bergmann Center of Biomaterials Dresden, 01069 Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Polymer Research Dresden and Max Bergmann Center of Biomaterials Dresden, 01069 Dresden, Germany","institution_ids":["https://openalex.org/I4210107560"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5002901309"],"corresponding_institution_ids":["https://openalex.org/I4210107560","https://openalex.org/I4210111834"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":1.2537,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.73967329,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"88","issue":"1","first_page":"527","last_page":"534"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10923","display_name":"Force Microscopy Techniques and Applications","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fibronectin-fibrillogenesis","display_name":"fibronectin fibrillogenesis","score":0.9800000190734863},{"id":"https://openalex.org/keywords/stress-fibers","display_name":"stress fibers","score":0.7950000166893005},{"id":"https://openalex.org/keywords/alpha-actinin","display_name":"alpha-actinin","score":0.9660000205039978},{"id":"https://openalex.org/keywords/focal-adhesions","display_name":"focal adhesions","score":0.9810000061988831},{"id":"https://openalex.org/keywords/actin-filaments","display_name":"F-actin","score":0.7110000252723694},{"id":"https://openalex.org/keywords/polymer-substrates","display_name":"polymer substrates","score":0.4819999933242798},{"id":"https://openalex.org/keywords/cell-substrate-interaction","display_name":"cell-substrate interaction","score":0.4779999852180481}],"concepts":[{"id":"https://openalex.org/C86492073","wikidata":"https://www.wikidata.org/wiki/Q413766","display_name":"Fibronectin","level":3,"score":0.8974269032478333},{"id":"https://openalex.org/C147259501","wikidata":"https://www.wikidata.org/wiki/Q14864949","display_name":"Fibrillogenesis","level":3,"score":0.6989200115203857},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.6768929958343506},{"id":"https://openalex.org/C40209533","wikidata":"https://www.wikidata.org/wiki/Q5147828","display_name":"Colocalization","level":2,"score":0.6362639665603638},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.5303770899772644},{"id":"https://openalex.org/C2777289219","wikidata":"https://www.wikidata.org/wiki/Q7632154","display_name":"Substrate (aquarium)","level":2,"score":0.5203937292098999},{"id":"https://openalex.org/C45206210","wikidata":"https://www.wikidata.org/wiki/Q2415817","display_name":"Nanoscopic scale","level":2,"score":0.5103044509887695},{"id":"https://openalex.org/C2993400109","wikidata":"https://www.wikidata.org/wiki/Q329638","display_name":"Actin cytoskeleton","level":4,"score":0.4950837194919586},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4875645041465759},{"id":"https://openalex.org/C27523624","wikidata":"https://www.wikidata.org/wiki/Q14860849","display_name":"Fibril","level":2,"score":0.4767528474330902},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.4573478400707245},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.4414187967777252},{"id":"https://openalex.org/C2908543132","wikidata":"https://www.wikidata.org/wiki/Q413766","display_name":"Fibronectins","level":4,"score":0.43598687648773193},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.36914050579071045},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.3606742024421692},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.29038330912590027},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2730758488178253},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.26737064123153687},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2568194270133972},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2316950261592865},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1480121910572052},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.14353039860725403},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000185","descriptor_name":"Actinin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000327","descriptor_name":"Adsorption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003432","descriptor_name":"Cross-Linking Reagents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D003599","descriptor_name":"Cytoskeleton","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005353","descriptor_name":"Fibronectins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008856","descriptor_name":"Microscopy, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018613","descriptor_name":"Microscopy, Confocal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018625","descriptor_name":"Microscopy, Atomic Force","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022001","descriptor_name":"Focal Adhesions","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1529/biophysj.104.048074","doi":"https://doi.org/10.1529/biophysj.104.048074","is_oa":true,"landing_page_url":"https://doi.org/10.1529/biophysj.104.048074","pdf_url":null,"source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},{"id":"pmid:15533920","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15533920","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical journal","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1305030","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1305030/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophys J","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1529/biophysj.104.048074","doi":"https://doi.org/10.1529/biophysj.104.048074","is_oa":true,"landing_page_url":"https://doi.org/10.1529/biophysj.104.048074","pdf_url":null,"source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W297918892","https://openalex.org/W1967816819","https://openalex.org/W1967922151","https://openalex.org/W1981252803","https://openalex.org/W1993607801","https://openalex.org/W1997283863","https://openalex.org/W2012297345","https://openalex.org/W2017900646","https://openalex.org/W2023982988","https://openalex.org/W2029621530","https://openalex.org/W2030795397","https://openalex.org/W2032275376","https://openalex.org/W2041578482","https://openalex.org/W2045032642","https://openalex.org/W2064203989","https://openalex.org/W2066274406","https://openalex.org/W2068092779","https://openalex.org/W2078393006","https://openalex.org/W2079586645","https://openalex.org/W2083509842","https://openalex.org/W2083638734","https://openalex.org/W2093657979","https://openalex.org/W2094121810","https://openalex.org/W2100202577","https://openalex.org/W2101712645","https://openalex.org/W2105402224","https://openalex.org/W2122840995","https://openalex.org/W2125644189","https://openalex.org/W2132755702","https://openalex.org/W2146376600","https://openalex.org/W2152002380","https://openalex.org/W2157024197","https://openalex.org/W2162857895","https://openalex.org/W2165697065","https://openalex.org/W2168783089"],"related_works":["https://openalex.org/W2014817128","https://openalex.org/W1975300275","https://openalex.org/W2026738531","https://openalex.org/W2963192242","https://openalex.org/W2583702311","https://openalex.org/W70748844","https://openalex.org/W2016272412","https://openalex.org/W2143918607","https://openalex.org/W1964585209","https://openalex.org/W2138393601"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}