{"id":"https://openalex.org/W2018692335","doi":"https://doi.org/10.1038/sj.mp.4001854","title":"Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease","display_name":"Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease","publication_year":2006,"publication_date":"2006-06-20","ids":{"openalex":"https://openalex.org/W2018692335","doi":"https://doi.org/10.1038/sj.mp.4001854","mag":"2018692335","pmid":"https://pubmed.ncbi.nlm.nih.gov/16786033"},"language":"en","primary_location":{"id":"doi:10.1038/sj.mp.4001854","doi":"https://doi.org/10.1038/sj.mp.4001854","is_oa":false,"landing_page_url":"https://doi.org/10.1038/sj.mp.4001854","pdf_url":null,"source":{"id":"https://openalex.org/S71149355","display_name":"Molecular Psychiatry","issn_l":"1359-4184","issn":["1359-4184","1476-5578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Psychiatry","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040281675","display_name":"Ian James Martins","orcid":"https://orcid.org/0000-0002-2390-1501","observed_orcids":["https://orcid.org/0000-0002-2390-1501"]},"institutions":[{"id":"https://openalex.org/I12079687","display_name":"Edith Cowan University","ror":"https://ror.org/05jhnwe22","country_code":"AU","type":"education","lineage":["https://openalex.org/I12079687"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"I J Martins","raw_affiliation_strings":["Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia","institution_ids":["https://openalex.org/I12079687"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034316552","display_name":"Eugene Hone","orcid":"https://orcid.org/0000-0001-6708-3718","observed_orcids":["https://orcid.org/0000-0001-6708-3718"]},"institutions":[{"id":"https://openalex.org/I12079687","display_name":"Edith Cowan University","ror":"https://ror.org/05jhnwe22","country_code":"AU","type":"education","lineage":["https://openalex.org/I12079687"]},{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2800639565","display_name":"Hollywood Private Hospital","ror":"https://ror.org/0101aa973","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800639565"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"E Hone","raw_affiliation_strings":["Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia","Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, WA, Australia","Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, Australia","Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia","institution_ids":["https://openalex.org/I12079687"]},{"raw_affiliation_string":"Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, WA, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800639565"]},{"raw_affiliation_string":"Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, Australia","institution_ids":["https://openalex.org/I12079687"]},{"raw_affiliation_string":"Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800639565"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101864641","display_name":"Jonathan K. Foster","orcid":"https://orcid.org/0000-0002-9439-0884","observed_orcids":["https://orcid.org/0000-0002-9439-0884","https://orcid.org/0000-0003-4819-6375","https://orcid.org/0000-0002-7842-6277"]},"institutions":[{"id":"https://openalex.org/I12079687","display_name":"Edith Cowan University","ror":"https://ror.org/05jhnwe22","country_code":"AU","type":"education","lineage":["https://openalex.org/I12079687"]},{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2800639565","display_name":"Hollywood Private Hospital","ror":"https://ror.org/0101aa973","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800639565"]},{"id":"https://openalex.org/I2800882159","display_name":"Government of Western Australia Department of Health","ror":"https://ror.org/01epcny94","country_code":"AU","type":"government","lineage":["https://openalex.org/I2799506148","https://openalex.org/I2800882159"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"J K Foster","raw_affiliation_strings":["Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia","Health Department of Western Australia, Neurosciences Unit, Mt Claremont, WA, Australia","Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, WA, Australia","Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, Australia","Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia","institution_ids":["https://openalex.org/I12079687"]},{"raw_affiliation_string":"Health Department of Western Australia, Neurosciences Unit, Mt Claremont, WA, Australia","institution_ids":["https://openalex.org/I2800882159"]},{"raw_affiliation_string":"Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, WA, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800639565"]},{"raw_affiliation_string":"Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, Australia","institution_ids":["https://openalex.org/I12079687"]},{"raw_affiliation_string":"Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800639565"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060786860","display_name":"Sandra I. S\u00fcnram\u2010Lea","orcid":"https://orcid.org/0000-0001-9889-9867","observed_orcids":["https://orcid.org/0000-0001-9889-9867"]},"institutions":[{"id":"https://openalex.org/I67415387","display_name":"Lancaster University","ror":"https://ror.org/04f2nsd36","country_code":"GB","type":"education","lineage":["https://openalex.org/I67415387"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S I S\u00fcnram-Lea","raw_affiliation_strings":["Department of Psychology, University of Lancaster, Lancaster, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, University of Lancaster, Lancaster, UK","institution_ids":["https://openalex.org/I67415387"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074669466","display_name":"Anastazija Gnjec","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12079687","display_name":"Edith Cowan University","ror":"https://ror.org/05jhnwe22","country_code":"AU","type":"education","lineage":["https://openalex.org/I12079687"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"A Gnjec","raw_affiliation_strings":["Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia","Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia","institution_ids":["https://openalex.org/I12079687"]},{"raw_affiliation_string":"Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, Australia","institution_ids":["https://openalex.org/I12079687"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110031282","display_name":"S J Fuller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12079687","display_name":"Edith Cowan University","ror":"https://ror.org/05jhnwe22","country_code":"AU","type":"education","lineage":["https://openalex.org/I12079687"]},{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2800639565","display_name":"Hollywood Private Hospital","ror":"https://ror.org/0101aa973","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800639565"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"S J Fuller","raw_affiliation_strings":["Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia","Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, WA, Australia","Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, Australia","Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia","institution_ids":["https://openalex.org/I12079687"]},{"raw_affiliation_string":"Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, WA, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800639565"]},{"raw_affiliation_string":"Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, Australia","institution_ids":["https://openalex.org/I12079687"]},{"raw_affiliation_string":"Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800639565"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039351765","display_name":"David A Nolan","orcid":"https://orcid.org/0000-0002-0743-8801","observed_orcids":["https://orcid.org/0000-0002-0743-8801"]},"institutions":[{"id":"https://openalex.org/I176790772","display_name":"Murdoch University","ror":"https://ror.org/00r4sry34","country_code":"AU","type":"education","lineage":["https://openalex.org/I176790772"]},{"id":"https://openalex.org/I2799740997","display_name":"Royal Perth Hospital","ror":"https://ror.org/00zc2xc51","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799506148","https://openalex.org/I2799740997","https://openalex.org/I2800882159","https://openalex.org/I4388446364","https://openalex.org/I4405257575"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"D Nolan","raw_affiliation_strings":["Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital Wellington St, and Murdoch University, Perth, WA, Australia","Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital Wellington St, and Murdoch University, Perth, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital Wellington St, and Murdoch University, Perth, WA, Australia","institution_ids":["https://openalex.org/I176790772","https://openalex.org/I2799740997"]},{"raw_affiliation_string":"Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital Wellington St, and Murdoch University, Perth, Australia","institution_ids":["https://openalex.org/I176790772","https://openalex.org/I2799740997"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103144641","display_name":"Sam Gandy","orcid":"https://orcid.org/0000-0001-6455-4721","observed_orcids":["https://orcid.org/0000-0001-6455-4721"]},"institutions":[{"id":"https://openalex.org/I12079687","display_name":"Edith Cowan University","ror":"https://ror.org/05jhnwe22","country_code":"AU","type":"education","lineage":["https://openalex.org/I12079687"]},{"id":"https://openalex.org/I149251103","display_name":"Thomas Jefferson University","ror":"https://ror.org/00ysqcn41","country_code":"US","type":"education","lineage":["https://openalex.org/I149251103"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"S E Gandy","raw_affiliation_strings":["Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia","Farber Institute for Neurosciences, Thomas Jefferson University, Philadelphia, PA, USA","Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, Australia","Farber Institute for Neurosciences, Thomas Jefferson University, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia","institution_ids":["https://openalex.org/I12079687"]},{"raw_affiliation_string":"Farber Institute for Neurosciences, Thomas Jefferson University, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I149251103"]},{"raw_affiliation_string":"Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, Australia","institution_ids":["https://openalex.org/I12079687"]},{"raw_affiliation_string":"Farber Institute for Neurosciences, Thomas Jefferson University, Philadelphia, USA","institution_ids":["https://openalex.org/I149251103"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065618928","display_name":"Ralph Nigel Martins","orcid":"https://orcid.org/0000-0002-4828-9363","observed_orcids":["https://orcid.org/0000-0002-4828-9363"]},"institutions":[{"id":"https://openalex.org/I12079687","display_name":"Edith Cowan University","ror":"https://ror.org/05jhnwe22","country_code":"AU","type":"education","lineage":["https://openalex.org/I12079687"]},{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2800639565","display_name":"Hollywood Private Hospital","ror":"https://ror.org/0101aa973","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800639565"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"R N Martins","raw_affiliation_strings":["Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia","Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, WA, Australia","Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, Australia","Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, WA, Australia","institution_ids":["https://openalex.org/I12079687"]},{"raw_affiliation_string":"Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, WA, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800639565"]},{"raw_affiliation_string":"Alzheimer's and Ageing, School of Biomedical and Sports Science, Edith Cowan University, Perth, Australia","institution_ids":["https://openalex.org/I12079687"]},{"raw_affiliation_string":"Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry & Clinical Neurosciences, and University of Western Australia, Hollywood Private Hospital, Nedlands, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800639565"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5065618928"],"corresponding_institution_ids":["https://openalex.org/I12079687","https://openalex.org/I177877127","https://openalex.org/I2800639565"],"apc_list":{"value":5490,"currency":"USD","value_usd":5490},"apc_paid":null,"fwci":2.5616,"has_fulltext":false,"cited_by_count":392,"citation_normalized_percentile":{"value":0.93248945,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"11","issue":"8","first_page":"721","last_page":"736"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.030700000002980232,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/apolipoprotein-e","display_name":"apolipoprotein E","score":0.8629999756813049},{"id":"https://openalex.org/keywords/apoe-epsilon4","display_name":"APOE \u03b54","score":0.9700000286102295},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9319999814033508},{"id":"https://openalex.org/keywords/cholesterol-metabolism","display_name":"cholesterol metabolism","score":0.9509999752044678},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.8820000290870667},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.8450000286102295},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.5640000104904175},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.6790000200271606},{"id":"https://openalex.org/keywords/amyloid-beta-clearance","display_name":"amyloid-beta clearance","score":0.7680000066757202},{"id":"https://openalex.org/keywords/app-processing","display_name":"APP processing","score":0.8889999985694885},{"id":"https://openalex.org/keywords/glucose-regulation","display_name":"glucose regulation","score":0.6880000233650208},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.7720000147819519},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8450000286102295},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.7739999890327454},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.6269999742507935},{"id":"https://openalex.org/keywords/lifestyle-modification","display_name":"lifestyle modification","score":0.3529999852180481}],"concepts":[{"id":"https://openalex.org/C57089818","wikidata":"https://www.wikidata.org/wiki/Q424728","display_name":"Apolipoprotein E","level":3,"score":0.6860036849975586},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.6705868244171143},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6591846942901611},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5989455580711365},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5973358750343323},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.5672622919082642},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.5639298558235168},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5103492140769958},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.4977617561817169},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4792602062225342},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.4635889232158661},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.4633629024028778},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.4207088351249695},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.41977500915527344}],"mesh":[{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D001057","descriptor_name":"Apolipoproteins E","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1038/sj.mp.4001854","doi":"https://doi.org/10.1038/sj.mp.4001854","is_oa":false,"landing_page_url":"https://doi.org/10.1038/sj.mp.4001854","pdf_url":null,"source":{"id":"https://openalex.org/S71149355","display_name":"Molecular Psychiatry","issn_l":"1359-4184","issn":["1359-4184","1476-5578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Psychiatry","raw_type":"journal-article"},{"id":"pmid:16786033","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16786033","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular psychiatry","raw_type":"Journal Article"},{"id":"pmh:oai:alma.61MUN_INST:11135751330007891","doi":null,"is_oa":false,"landing_page_url":"https://researchportal.murdoch.edu.au/esploro/outputs/journalArticle/Apolipoprotein-E-cholesterol-metabolism-diabetes-and/991005542281807891","pdf_url":null,"source":{"id":"https://openalex.org/S4306400274","display_name":"Murdoch University Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I176790772","host_organization_name":"Murdoch University","host_organization_lineage":["https://openalex.org/I176790772"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"pmh:oai:pure.atira.dk:publications/1490dc7e-4a18-400b-aa7d-557579551e3f","doi":null,"is_oa":false,"landing_page_url":"https://research-repository.uwa.edu.au/en/publications/1490dc7e-4a18-400b-aa7d-557579551e3f","pdf_url":null,"source":{"id":"https://openalex.org/S4306402492","display_name":"UWA Profiles and Research Repository (UWA)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Martins, I, Hone, E, Foster, J, Sunram-Lea, S I, Gnjec, A, Fuller, S J, Nolan, D, Gandy, S E & Martins, R 2006, 'Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease', Molecular Psychiatry, vol. 11, no. 8, pp. 721-736. https://doi.org/10.1038/sj.mp.4001854","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:researchrepository.murdoch.edu.au:11931","doi":null,"is_oa":false,"landing_page_url":"http://researchrepository.murdoch.edu.au/id/eprint/11931/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400274","display_name":"Murdoch University Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I176790772","host_organization_name":"Murdoch University","host_organization_lineage":["https://openalex.org/I176790772"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Martins, I.J., Hone, E., Foster, J.K., S, S.I., Gnjec, A., Fuller, S.J., Nolan, D. <http://researchrepository.murdoch.edu.au/view/author/Nolan, David.html>, Gandy, S.E. and Martins, R.N. (2006) Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease. Molecular Psychiatry, 11 (8). pp. 721-736.","raw_type":"Journal Article"},{"id":"pmh:oai:ro.ecu.edu.au:ecuworks-2935","doi":null,"is_oa":false,"landing_page_url":"https://ro.ecu.edu.au/ecuworks/1936","pdf_url":null,"source":{"id":"https://openalex.org/S2765015692","display_name":"Australasian Journal of Paramedicine","issn_l":"2202-7270","issn":["2202-7270"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20"],"host_organization":"https://openalex.org/I4405272673","host_organization_name":"Australasian College of Paramedicine","host_organization_lineage":["https://openalex.org/I4405272673"],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research outputs pre 2011","raw_type":"journalarticle"},{"id":"pmh:oai:eprints.lancs.ac.uk:34838","doi":null,"is_oa":false,"landing_page_url":"https://eprints.lancs.ac.uk/id/eprint/34838/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401916","display_name":"Lancaster EPrints (Lancaster University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67415387","host_organization_name":"Lancaster University","host_organization_lineage":["https://openalex.org/I67415387"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1149445338","display_name":"Interdisciplinary Approach to Alzheimer Drug Discovery","funder_award_id":"P01AG010491","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":241,"referenced_works":["https://openalex.org/W1590756","https://openalex.org/W4166267","https://openalex.org/W8493967","https://openalex.org/W12222387","https://openalex.org/W39289750","https://openalex.org/W63174853","https://openalex.org/W134078131","https://openalex.org/W246056046","https://openalex.org/W300649860","https://openalex.org/W1443942943","https://openalex.org/W1487168219","https://openalex.org/W1491093025","https://openalex.org/W1540244875","https://openalex.org/W1543788907","https://openalex.org/W1545187077","https://openalex.org/W1549308915","https://openalex.org/W1551306548","https://openalex.org/W1557744319","https://openalex.org/W1584374592","https://openalex.org/W1594033512","https://openalex.org/W1622703765","https://openalex.org/W1629602451","https://openalex.org/W1731823889","https://openalex.org/W1736154854","https://openalex.org/W1770880387","https://openalex.org/W1816050387","https://openalex.org/W1858469465","https://openalex.org/W1874453010","https://openalex.org/W1906845271","https://openalex.org/W1908587496","https://openalex.org/W1942956086","https://openalex.org/W1953255974","https://openalex.org/W1963021413","https://openalex.org/W1963627192","https://openalex.org/W1963671893","https://openalex.org/W1964050087","https://openalex.org/W1965050626","https://openalex.org/W1965496447","https://openalex.org/W1967757559","https://openalex.org/W1968546707","https://openalex.org/W1969976310","https://openalex.org/W1970018958","https://openalex.org/W1971729688","https://openalex.org/W1971781735","https://openalex.org/W1972781517","https://openalex.org/W1973630137","https://openalex.org/W1975212930","https://openalex.org/W1975806945","https://openalex.org/W1979959143","https://openalex.org/W1980859319","https://openalex.org/W1981101710","https://openalex.org/W1981362787","https://openalex.org/W1982154094","https://openalex.org/W1984088065","https://openalex.org/W1984964878","https://openalex.org/W1988496865","https://openalex.org/W1990061193","https://openalex.org/W1992442610","https://openalex.org/W1993629125","https://openalex.org/W1993867495","https://openalex.org/W1994281506","https://openalex.org/W1994497989","https://openalex.org/W1996214804","https://openalex.org/W1996521902","https://openalex.org/W1997913988","https://openalex.org/W2001688761","https://openalex.org/W2003527151","https://openalex.org/W2003845745","https://openalex.org/W2003890494","https://openalex.org/W2004131059","https://openalex.org/W2005343296","https://openalex.org/W2005650787","https://openalex.org/W2006217609","https://openalex.org/W2006409771","https://openalex.org/W2007202486","https://openalex.org/W2008496629","https://openalex.org/W2009111659","https://openalex.org/W2011424449","https://openalex.org/W2011563044","https://openalex.org/W2012268537","https://openalex.org/W2013111251","https://openalex.org/W2013367070","https://openalex.org/W2014223577","https://openalex.org/W2015882290","https://openalex.org/W2017007470","https://openalex.org/W2017355002","https://openalex.org/W2018001209","https://openalex.org/W2019256890","https://openalex.org/W2020291960","https://openalex.org/W2020460543","https://openalex.org/W2021084523","https://openalex.org/W2021181758","https://openalex.org/W2022158649","https://openalex.org/W2025003635","https://openalex.org/W2026985134","https://openalex.org/W2028195118","https://openalex.org/W2031715075","https://openalex.org/W2032920422","https://openalex.org/W2033069335","https://openalex.org/W2033382511","https://openalex.org/W2034968148","https://openalex.org/W2035247878","https://openalex.org/W2035703501","https://openalex.org/W2036680386","https://openalex.org/W2037500564","https://openalex.org/W2039210191","https://openalex.org/W2039974215","https://openalex.org/W2040522662","https://openalex.org/W2044416233","https://openalex.org/W2044494092","https://openalex.org/W2044640674","https://openalex.org/W2045471895","https://openalex.org/W2046123800","https://openalex.org/W2046209489","https://openalex.org/W2046847750","https://openalex.org/W2047202269","https://openalex.org/W2047478253","https://openalex.org/W2047613132","https://openalex.org/W2047989388","https://openalex.org/W2048509804","https://openalex.org/W2049430814","https://openalex.org/W2050640530","https://openalex.org/W2050920707","https://openalex.org/W2051993731","https://openalex.org/W2052828385","https://openalex.org/W2054543840","https://openalex.org/W2055325336","https://openalex.org/W2057766834","https://openalex.org/W2058046914","https://openalex.org/W2058473463","https://openalex.org/W2058513135","https://openalex.org/W2059559668","https://openalex.org/W2059806453","https://openalex.org/W2059824458","https://openalex.org/W2060595700","https://openalex.org/W2060644484","https://openalex.org/W2060946539","https://openalex.org/W2063251245","https://openalex.org/W2063951693","https://openalex.org/W2064668117","https://openalex.org/W2064707735","https://openalex.org/W2065663907","https://openalex.org/W2066630911","https://openalex.org/W2067064610","https://openalex.org/W2068166353","https://openalex.org/W2068631553","https://openalex.org/W2069638209","https://openalex.org/W2070490664","https://openalex.org/W2072682191","https://openalex.org/W2074249519","https://openalex.org/W2076131392","https://openalex.org/W2076517751","https://openalex.org/W2077207045","https://openalex.org/W2078868323","https://openalex.org/W2080305329","https://openalex.org/W2081826643","https://openalex.org/W2081881251","https://openalex.org/W2082336678","https://openalex.org/W2083454265","https://openalex.org/W2084113115","https://openalex.org/W2085410081","https://openalex.org/W2086793697","https://openalex.org/W2087139157","https://openalex.org/W2087641892","https://openalex.org/W2088642279","https://openalex.org/W2089189677","https://openalex.org/W2090150925","https://openalex.org/W2090221075","https://openalex.org/W2090253176","https://openalex.org/W2092157460","https://openalex.org/W2094936415","https://openalex.org/W2095853881","https://openalex.org/W2096012124","https://openalex.org/W2096693266","https://openalex.org/W2097157695","https://openalex.org/W2098460507","https://openalex.org/W2098536076","https://openalex.org/W2099556509","https://openalex.org/W2099765629","https://openalex.org/W2100610042","https://openalex.org/W2100875841","https://openalex.org/W2103609019","https://openalex.org/W2104409730","https://openalex.org/W2107610460","https://openalex.org/W2109464535","https://openalex.org/W2109958697","https://openalex.org/W2110961285","https://openalex.org/W2111001050","https://openalex.org/W2111119128","https://openalex.org/W2112735281","https://openalex.org/W2113934386","https://openalex.org/W2114063969","https://openalex.org/W2114597265","https://openalex.org/W2119556701","https://openalex.org/W2122832642","https://openalex.org/W2124097986","https://openalex.org/W2124214624","https://openalex.org/W2128565374","https://openalex.org/W2129678592","https://openalex.org/W2131068139","https://openalex.org/W2133019124","https://openalex.org/W2134417042","https://openalex.org/W2135475959","https://openalex.org/W2137023074","https://openalex.org/W2139277690","https://openalex.org/W2139877281","https://openalex.org/W2141545294","https://openalex.org/W2145757273","https://openalex.org/W2148918646","https://openalex.org/W2152448842","https://openalex.org/W2152753574","https://openalex.org/W2154267987","https://openalex.org/W2156000283","https://openalex.org/W2156220037","https://openalex.org/W2157665412","https://openalex.org/W2157685156","https://openalex.org/W2158894504","https://openalex.org/W2158965128","https://openalex.org/W2160250384","https://openalex.org/W2162294352","https://openalex.org/W2163209521","https://openalex.org/W2163417125","https://openalex.org/W2165951708","https://openalex.org/W2169555689","https://openalex.org/W2170343067","https://openalex.org/W2170460248","https://openalex.org/W2330535515","https://openalex.org/W2331038954","https://openalex.org/W2406041196","https://openalex.org/W2409807723","https://openalex.org/W2412770350","https://openalex.org/W3026115269","https://openalex.org/W4210422950","https://openalex.org/W4212956217","https://openalex.org/W4231712045","https://openalex.org/W4232841197","https://openalex.org/W4285719527","https://openalex.org/W4293875546","https://openalex.org/W4294250618","https://openalex.org/W4300007302","https://openalex.org/W6759766127"],"related_works":["https://openalex.org/W1997210148","https://openalex.org/W1509846655","https://openalex.org/W1990027951","https://openalex.org/W7009819760","https://openalex.org/W2032605307","https://openalex.org/W4206062763","https://openalex.org/W1993668532","https://openalex.org/W2944515500","https://openalex.org/W2165995341","https://openalex.org/W2083719092"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":16},{"year":2024,"cited_by_count":20},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":27},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":22},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":14},{"year":2014,"cited_by_count":33},{"year":2013,"cited_by_count":26},{"year":2012,"cited_by_count":21}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}