{"id":"https://openalex.org/W2018691822","doi":"https://doi.org/10.1016/s0196-9781(01)00651-9","title":"cis-peptide bond mimetic tetrazole analogs of the insect kinins identify the active conformation","display_name":"cis-peptide bond mimetic tetrazole analogs of the insect kinins identify the active conformation","publication_year":2002,"publication_date":"2002-04-01","ids":{"openalex":"https://openalex.org/W2018691822","doi":"https://doi.org/10.1016/s0196-9781(01)00651-9","mag":"2018691822","pmid":"https://pubmed.ncbi.nlm.nih.gov/11897390"},"language":"en","primary_location":{"id":"doi:10.1016/s0196-9781(01)00651-9","doi":"https://doi.org/10.1016/s0196-9781(01)00651-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0196-9781(01)00651-9","pdf_url":null,"source":{"id":"https://openalex.org/S120382301","display_name":"Peptides","issn_l":"0196-9781","issn":["0196-9781","1873-5169"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Peptides","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042422062","display_name":"Ronald J. Nachman","orcid":"https://orcid.org/0000-0001-8940-5984","observed_orcids":["https://orcid.org/0000-0001-8940-5984"]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ronald J Nachman","raw_affiliation_strings":["Veterinary Entomology Research Laboratory, ARS, U.S. Department of Agriculture, 2881 F/B Road, College Station, TX 77845, USA. nachman@tamu.edu","Veterinary Entomology Research Laboratory, ARS, U.S. Department of Agriculture, 2881 F/B Road, College Station, TX 77845, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterinary Entomology Research Laboratory, ARS, U.S. Department of Agriculture, 2881 F/B Road, College Station, TX 77845, USA. nachman@tamu.edu","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"raw_affiliation_string":"Veterinary Entomology Research Laboratory, ARS, U.S. Department of Agriculture, 2881 F/B Road, College Station, TX 77845, USA","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105420724","display_name":"Janusz Zabrocki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I188884621","display_name":"Lodz University of Technology","ror":"https://ror.org/00s8fpf52","country_code":"PL","type":"education","lineage":["https://openalex.org/I188884621"]}],"countries":["PL","US"],"is_corresponding":false,"raw_author_name":"Janusz Zabrocki","raw_affiliation_strings":["Technical University of Lodz, 90-924 Lodz, Poland","Veterinary Entomology Research Laboratory, ARS, U.S. Department of Agriculture, 2881 F/B Road, College Station, TX 77845, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Lodz, 90-924 Lodz, Poland","institution_ids":["https://openalex.org/I188884621"]},{"raw_affiliation_string":"Veterinary Entomology Research Laboratory, ARS, U.S. Department of Agriculture, 2881 F/B Road, College Station, TX 77845, USA","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081028300","display_name":"Jacek Olczak","orcid":"https://orcid.org/0000-0001-9932-2373","observed_orcids":["https://orcid.org/0000-0001-9932-2373"]},"institutions":[{"id":"https://openalex.org/I188884621","display_name":"Lodz University of Technology","ror":"https://ror.org/00s8fpf52","country_code":"PL","type":"education","lineage":["https://openalex.org/I188884621"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Jacek Olczak","raw_affiliation_strings":["Technical University of Lodz, 90-924 Lodz, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Lodz, 90-924 Lodz, Poland","institution_ids":["https://openalex.org/I188884621"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113872751","display_name":"Howard J. Williams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Howard J Williams","raw_affiliation_strings":["Department of Chemistry, Texas A&M University, College Station, TX 77840, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Texas A&M University, College Station, TX 77840, USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042590673","display_name":"Guillermo Moyna","orcid":"https://orcid.org/0000-0002-0727-1079","observed_orcids":["https://orcid.org/0000-0002-0727-1079"]},"institutions":[{"id":"https://openalex.org/I110357561","display_name":"University of the Sciences","ror":"https://ror.org/048gmay44","country_code":"US","type":"education","lineage":["https://openalex.org/I110357561"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guillermo Moyna","raw_affiliation_strings":["Department of Chemistry & Biochemistry, University of the Sciences in Philadelphia, Philadelphia, PA 19104, USA","Department of Chemistry, Texas A&M University, College Station, TX 77840, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry & Biochemistry, University of the Sciences in Philadelphia, Philadelphia, PA 19104, USA","institution_ids":["https://openalex.org/I110357561"]},{"raw_affiliation_string":"Department of Chemistry, Texas A&M University, College Station, TX 77840, USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010126262","display_name":"A. Ian Scott","orcid":"https://orcid.org/0000-0003-0001-7024","observed_orcids":["https://orcid.org/0000-0003-0001-7024"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A Ian Scott","raw_affiliation_strings":["Department of Chemistry, Texas A&M University, College Station, TX 77840, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Texas A&M University, College Station, TX 77840, USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109035464","display_name":"Geoffrey M. Coast","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98259816","display_name":"Birkbeck, University of London","ror":"https://ror.org/02mb95055","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I98259816"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Geoffrey M Coast","raw_affiliation_strings":["School of Biological Sciences, Birkbeck College, London WC1E 7HX, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Sciences, Birkbeck College, London WC1E 7HX, UK","institution_ids":["https://openalex.org/I98259816"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5042422062"],"corresponding_institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"],"apc_list":{"value":3710,"currency":"USD","value_usd":3710},"apc_paid":null,"fwci":3.0472,"has_fulltext":false,"cited_by_count":62,"citation_normalized_percentile":{"value":0.90937808,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"23","issue":"4","first_page":"709","last_page":"716"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.9160000085830688,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.9160000085830688,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.04670000076293945,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13265","display_name":"Synthesis of Tetrazole Derivatives","score":0.016499999910593033,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuropeptides","display_name":"neuropeptides","score":0.7879999876022339},{"id":"https://openalex.org/keywords/beta-turn-conformation","display_name":"beta-turn conformation","score":0.8169999718666077},{"id":"https://openalex.org/keywords/active-conformation","display_name":"active conformation","score":0.6779999732971191},{"id":"https://openalex.org/keywords/diuretic-activity","display_name":"diuretic activity","score":0.9190000295639038},{"id":"https://openalex.org/keywords/receptor-antagonists","display_name":"receptor antagonists","score":0.7289999723434448},{"id":"https://openalex.org/keywords/receptor-agonists","display_name":"receptor agonists","score":0.6779999732971191},{"id":"https://openalex.org/keywords/insect-water-balance","display_name":"insect water balance","score":0.609000027179718},{"id":"https://openalex.org/keywords/insect-pest-control","display_name":"insect pest control","score":0.5730000138282776}],"concepts":[{"id":"https://openalex.org/C45197812","wikidata":"https://www.wikidata.org/wiki/Q24787539","display_name":"Pentapeptide repeat","level":3,"score":0.6978647708892822},{"id":"https://openalex.org/C2777612826","wikidata":"https://www.wikidata.org/wiki/Q1390","display_name":"Insect","level":2,"score":0.6264163255691528},{"id":"https://openalex.org/C2776246183","wikidata":"https://www.wikidata.org/wiki/Q421924","display_name":"Kinin","level":4,"score":0.6238223314285278},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6045968532562256},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.5621306896209717},{"id":"https://openalex.org/C60984968","wikidata":"https://www.wikidata.org/wiki/Q389172","display_name":"Cyclic peptide","level":3,"score":0.5332973003387451},{"id":"https://openalex.org/C31684184","wikidata":"https://www.wikidata.org/wiki/Q33293","display_name":"Peptide bond","level":3,"score":0.4742140769958496},{"id":"https://openalex.org/C116073593","wikidata":"https://www.wikidata.org/wiki/Q864491","display_name":"Biological activity","level":3,"score":0.4705139696598053},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.4136418402194977},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.404867947101593},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.35175174474716187},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2999834418296814},{"id":"https://openalex.org/C2779591629","wikidata":"https://www.wikidata.org/wiki/Q24745328","display_name":"Bradykinin","level":3,"score":0.21568450331687927},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.08892354369163513},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007313","descriptor_name":"Insecta","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007313","descriptor_name":"Insecta","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009479","descriptor_name":"Neuropeptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009479","descriptor_name":"Neuropeptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013777","descriptor_name":"Tetrazoles","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D013777","descriptor_name":"Tetrazoles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019476","descriptor_name":"Insect Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019476","descriptor_name":"Insect Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/s0196-9781(01)00651-9","doi":"https://doi.org/10.1016/s0196-9781(01)00651-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0196-9781(01)00651-9","pdf_url":null,"source":{"id":"https://openalex.org/S120382301","display_name":"Peptides","issn_l":"0196-9781","issn":["0196-9781","1873-5169"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Peptides","raw_type":"journal-article"},{"id":"pmid:11897390","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11897390","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Peptides","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.bbk.ac.uk.oai2:27577","doi":null,"is_oa":false,"landing_page_url":"https://eprints.bbk.ac.uk/id/eprint/27577/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400465","display_name":"BIROn (Birkbeck, University of London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I98259816","host_organization_name":"Birkbeck, University of London","host_organization_lineage":["https://openalex.org/I98259816"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W317663966","https://openalex.org/W568915783","https://openalex.org/W619948701","https://openalex.org/W1970793109","https://openalex.org/W1975117170","https://openalex.org/W1981074293","https://openalex.org/W1986315535","https://openalex.org/W1988487235","https://openalex.org/W2000864903","https://openalex.org/W2008156250","https://openalex.org/W2022947499","https://openalex.org/W2049064910","https://openalex.org/W2051319674","https://openalex.org/W2059289447","https://openalex.org/W2059523269","https://openalex.org/W2061618979","https://openalex.org/W2085526989","https://openalex.org/W2091244054","https://openalex.org/W2100654672","https://openalex.org/W2128498024","https://openalex.org/W2135519314","https://openalex.org/W2137266759","https://openalex.org/W2404869996","https://openalex.org/W2413939211"],"related_works":["https://openalex.org/W1981216293","https://openalex.org/W2096526026","https://openalex.org/W2027980195","https://openalex.org/W2156993035","https://openalex.org/W2041404786","https://openalex.org/W1849443200","https://openalex.org/W1996328330","https://openalex.org/W7095122343","https://openalex.org/W2059289447","https://openalex.org/W2051319674"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}