{"id":"https://openalex.org/W2018656142","doi":"https://doi.org/10.1128/aac.05381-11","title":"Micafungin Concentrations in the Plasma and Burn Eschar of Severely Burned Patients","display_name":"Micafungin Concentrations in the Plasma and Burn Eschar of Severely Burned Patients","publication_year":2011,"publication_date":"2011-11-15","ids":{"openalex":"https://openalex.org/W2018656142","doi":"https://doi.org/10.1128/aac.05381-11","mag":"2018656142","pmid":"https://pubmed.ncbi.nlm.nih.gov/22083486","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3264244"},"language":"en","primary_location":{"id":"doi:10.1128/aac.05381-11","doi":"https://doi.org/10.1128/aac.05381-11","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aac.05381-11","pdf_url":null,"source":{"id":"https://openalex.org/S47215897","display_name":"Antimicrobial Agents and Chemotherapy","issn_l":"0066-4804","issn":["0066-4804","1070-6283","1098-6596"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial Agents and Chemotherapy","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2018656142"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3264244/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089292835","display_name":"Junichi Sasaki","orcid":"https://orcid.org/0000-0002-5190-8524","observed_orcids":["https://orcid.org/0000-0002-5190-8524"]},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Junichi Sasaki","raw_affiliation_strings":["Department of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan","institution_ids":["https://openalex.org/I203951103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009386197","display_name":"Satoshi Yamanouchi","orcid":"https://orcid.org/0009-0003-7832-8196","observed_orcids":["https://orcid.org/0009-0003-7832-8196"]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Satoshi Yamanouchi","raw_affiliation_strings":["Division of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","bDivision of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","institution_ids":["https://openalex.org/I201537933"]},{"raw_affiliation_string":"bDivision of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013445506","display_name":"Daisuke Kudo","orcid":"https://orcid.org/0000-0001-8213-5176","observed_orcids":["https://orcid.org/0000-0001-8213-5176"]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Daisuke Kudo","raw_affiliation_strings":["Division of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","bDivision of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","institution_ids":["https://openalex.org/I201537933"]},{"raw_affiliation_string":"bDivision of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tomoyuki Endo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoyuki Endo","raw_affiliation_strings":["Division of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","bDivision of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","institution_ids":["https://openalex.org/I201537933"]},{"raw_affiliation_string":"bDivision of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013038111","display_name":"Ryosuke Nomura","orcid":"https://orcid.org/0009-0009-9282-3218","observed_orcids":["https://orcid.org/0009-0009-9282-3218"]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryosuke Nomura","raw_affiliation_strings":["Division of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","bDivision of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","institution_ids":["https://openalex.org/I201537933"]},{"raw_affiliation_string":"bDivision of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078623020","display_name":"Kiyotsugu Takuma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kiyotsugu Takuma","raw_affiliation_strings":["Department of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan","aDepartment of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan","institution_ids":["https://openalex.org/I203951103"]},{"raw_affiliation_string":"aDepartment of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan","institution_ids":["https://openalex.org/I203951103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084473249","display_name":"Shigeki Kushimoto","orcid":"https://orcid.org/0000-0001-9232-5782","observed_orcids":["https://orcid.org/0000-0001-9232-5782"]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeki Kushimoto","raw_affiliation_strings":["Division of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","bDivision of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","institution_ids":["https://openalex.org/I201537933"]},{"raw_affiliation_string":"bDivision of Emergency Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004124638","display_name":"Yotaro Shinozawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405282617","display_name":"International University of Health and Welfare Hospital","ror":"https://ror.org/0055rzm47","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405282617"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yotaro Shinozawa","raw_affiliation_strings":["Department of Emergency Medicine, International University of Health and Welfare Hospital, Tochigi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, International University of Health and Welfare Hospital, Tochigi, Japan","institution_ids":["https://openalex.org/I4405282617"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059320146","display_name":"Satoshi Kishino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I23172683","display_name":"Meiji Pharmaceutical University","ror":"https://ror.org/00wm7p047","country_code":"JP","type":"education","lineage":["https://openalex.org/I23172683"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Satoshi Kishino","raw_affiliation_strings":["Department of Medication Use Analysis and Clinical Research, Meiji Pharmaceutical University, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medication Use Analysis and Clinical Research, Meiji Pharmaceutical University, Tokyo, Japan","institution_ids":["https://openalex.org/I23172683"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101132926","display_name":"Shingo Hori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shingo Hori","raw_affiliation_strings":["Department of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan","aDepartment of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan","institution_ids":["https://openalex.org/I203951103"]},{"raw_affiliation_string":"aDepartment of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan","institution_ids":["https://openalex.org/I203951103"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045373277","display_name":"Naoki Aikawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoki Aikawa","raw_affiliation_strings":["Department of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan","aDepartment of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan","institution_ids":["https://openalex.org/I203951103"]},{"raw_affiliation_string":"aDepartment of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan","institution_ids":["https://openalex.org/I203951103"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.3023,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.7798663,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"56","issue":"2","first_page":"1113","last_page":"1115"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy","score":0.008299999870359898,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11422","display_name":"Burn Injury Management and Outcomes","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/micafungin","display_name":"micafungin","score":1.0},{"id":"https://openalex.org/keywords/severe-burns","display_name":"severe burns","score":0.7940000295639038},{"id":"https://openalex.org/keywords/burn-eschar","display_name":"burn eschar","score":0.925000011920929},{"id":"https://openalex.org/keywords/plasma-drug-concentration","display_name":"plasma drug concentration","score":0.8769999742507935},{"id":"https://openalex.org/keywords/intravenous-infusion","display_name":"intravenous infusion","score":0.6510000228881836},{"id":"https://openalex.org/keywords/peak-and-trough-levels","display_name":"peak and trough levels","score":0.7429999709129333},{"id":"https://openalex.org/keywords/antifungal-pharmacokinetics","display_name":"antifungal pharmacokinetics","score":0.8199999928474426},{"id":"https://openalex.org/keywords/candida","display_name":"Candida","score":0.9200000166893005},{"id":"https://openalex.org/keywords/aspergillus","display_name":"Aspergillus","score":0.9980000257492065},{"id":"https://openalex.org/keywords/antifungal-susceptibility","display_name":"antifungal susceptibility","score":0.5440000295639038},{"id":"https://openalex.org/keywords/treatment-initiation-delay","display_name":"delayed treatment initiation","score":0.42500001192092896}],"concepts":[{"id":"https://openalex.org/C2779020398","wikidata":"https://www.wikidata.org/wiki/Q6827850","display_name":"Micafungin","level":4,"score":0.9762859344482422},{"id":"https://openalex.org/C2780206043","wikidata":"https://www.wikidata.org/wiki/Q2478746","display_name":"Eschar","level":2,"score":0.9604934453964233},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6802273988723755},{"id":"https://openalex.org/C112705442","wikidata":"https://www.wikidata.org/wiki/Q323936","display_name":"Pharmacokinetics","level":2,"score":0.45705553889274597},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3746669292449951},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3659389615058899},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3370571434497833},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2715005874633789},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.20408958196640015},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.1903163194656372},{"id":"https://openalex.org/C2779629538","wikidata":"https://www.wikidata.org/wiki/Q412223","display_name":"Amphotericin B","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000077551","descriptor_name":"Micafungin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D002056","descriptor_name":"Burns","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D002056","descriptor_name":"Burns","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002056","descriptor_name":"Burns","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009181","descriptor_name":"Mycoses","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009181","descriptor_name":"Mycoses","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D054714","descriptor_name":"Echinocandins","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D054714","descriptor_name":"Echinocandins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D054714","descriptor_name":"Echinocandins","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D055666","descriptor_name":"Lipopeptides","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D055666","descriptor_name":"Lipopeptides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D055666","descriptor_name":"Lipopeptides","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/aac.05381-11","doi":"https://doi.org/10.1128/aac.05381-11","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aac.05381-11","pdf_url":null,"source":{"id":"https://openalex.org/S47215897","display_name":"Antimicrobial Agents and Chemotherapy","issn_l":"0066-4804","issn":["0066-4804","1070-6283","1098-6596"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial Agents and Chemotherapy","raw_type":"journal-article"},{"id":"pmid:22083486","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22083486","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial agents and chemotherapy","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3264244","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3264244/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrob Agents Chemother","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.923.3175","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.923.3175","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://aac.asm.org/content/56/2/1113.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3264244","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3264244/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrob Agents Chemother","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1984382621","https://openalex.org/W2002205662","https://openalex.org/W2023601006","https://openalex.org/W2024387621","https://openalex.org/W2024539469","https://openalex.org/W2027169933","https://openalex.org/W2051897629","https://openalex.org/W2070259416","https://openalex.org/W2072984719","https://openalex.org/W2077201350","https://openalex.org/W2086009689","https://openalex.org/W2113939460","https://openalex.org/W2160288749","https://openalex.org/W3188513541"],"related_works":["https://openalex.org/W2003634149","https://openalex.org/W1596754636","https://openalex.org/W2489218777","https://openalex.org/W2147524990","https://openalex.org/W4246572817","https://openalex.org/W1836515571","https://openalex.org/W2762086739","https://openalex.org/W2053600394","https://openalex.org/W2334661258"],"abstract_inverted_index":{"Micafungin":[0,27,72],"concentrations":[1,73],"in":[2,44,74],"plasma":[3,46,76],"and":[4,41,51,77,83,97],"burn":[5,37,78],"eschar":[6,79],"after":[7,35,47],"daily":[8],"intravenous":[9],"infusion":[10],"(1":[11],"h)":[12],"of":[13,91],"micafungin":[14,92],"(200":[15],"to":[16],"300":[17],"mg)":[18],"were":[19,59,80],"investigated":[20],"for":[21,54,69],"six":[22],"patients":[23],"with":[24,61],"severe":[25],"burns.":[26],"treatment":[28],"was":[29],"initiated":[30],"more":[31,55],"than":[32,56,65,87],"72":[33],"h":[34],"the":[36,45,48,66,75,88],"injuries.":[38],"The":[39],"peak":[40],"trough":[42],"levels":[43],"initial":[49],"administration":[50],"repeated":[52],"administrations":[53],"4":[57],"days":[58],"comparable":[60],"or":[62],"slightly":[63],"lower":[64],"reported":[67,89],"values":[68],"healthy":[70],"volunteers.":[71],"between":[81],"3.6":[82],">1,000":[84],"times":[85],"higher":[86],"MIC(90)s":[90],"against":[93],"clinically":[94],"important":[95],"Candida":[96],"Aspergillus":[98],"species.":[99]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}