{"id":"https://openalex.org/W2018595771","doi":"https://doi.org/10.1089/ten.1999.5.35","title":"Engineering Bone Regeneration with Bioabsorbable Scaffolds with Novel Microarchitecture","display_name":"Engineering Bone Regeneration with Bioabsorbable Scaffolds with Novel Microarchitecture","publication_year":1999,"publication_date":"1999-02-01","ids":{"openalex":"https://openalex.org/W2018595771","doi":"https://doi.org/10.1089/ten.1999.5.35","mag":"2018595771","pmid":"https://pubmed.ncbi.nlm.nih.gov/10207188"},"language":"en","primary_location":{"id":"doi:10.1089/ten.1999.5.35","doi":"https://doi.org/10.1089/ten.1999.5.35","is_oa":false,"landing_page_url":"https://doi.org/10.1089/ten.1999.5.35","pdf_url":null,"source":{"id":"https://openalex.org/S164177214","display_name":"Tissue Engineering","issn_l":"1076-3279","issn":["1076-3279","1557-8690"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Engineering","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004825459","display_name":"Kyumin Whang","orcid":"https://orcid.org/0000-0002-4921-3707","observed_orcids":["https://orcid.org/0000-0002-4921-3707"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K. Whang","raw_affiliation_strings":["Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Illinois","Division of Biological Materials, Northwestern University Medical School, Chicago, Illinois","Division of Biological Materials, Northwestern University Medical School, Chicago, IL 60611-3008, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Illinois","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Division of Biological Materials, Northwestern University Medical School, Chicago, Illinois","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Division of Biological Materials, Northwestern University Medical School, Chicago, IL 60611-3008, USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073133450","display_name":"Kevin E. Healy","orcid":"https://orcid.org/0000-0002-8524-3671","observed_orcids":["https://orcid.org/0000-0002-8524-3671"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K.E. Healy","raw_affiliation_strings":["Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Illinois","Division of Biological Materials, Northwestern University Medical School, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Illinois","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Division of Biological Materials, Northwestern University Medical School, Chicago, Illinois","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044005242","display_name":"D. R. Elenz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D.R. Elenz","raw_affiliation_strings":["Department of Orthopaedic Surgery, Northwestern University Medical School, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Northwestern University Medical School, Chicago, Illinois","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111962741","display_name":"Ellis Kevin Nam","orcid":"https://orcid.org/0009-0000-7954-1704","observed_orcids":["https://orcid.org/0009-0000-7954-1704"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E.K. Nam","raw_affiliation_strings":["Department of Orthopaedic Surgery, Northwestern University Medical School, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Northwestern University Medical School, Chicago, Illinois","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090030042","display_name":"D. C. Tsai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D.C. Tsai","raw_affiliation_strings":["Department of Orthopaedic Surgery, Northwestern University Medical School, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Northwestern University Medical School, Chicago, Illinois","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010400112","display_name":"Carson H. Thomas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C.H. Thomas","raw_affiliation_strings":["Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Illinois","Division of Biological Materials, Northwestern University Medical School, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Illinois","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Division of Biological Materials, Northwestern University Medical School, Chicago, Illinois","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110311658","display_name":"Gordon W. Nuber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G.W. Nuber","raw_affiliation_strings":["Department of Orthopaedic Surgery, Northwestern University Medical School, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Northwestern University Medical School, Chicago, Illinois","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004489635","display_name":"Francis H. Glorieux","orcid":"https://orcid.org/0000-0001-6616-3484","observed_orcids":["https://orcid.org/0000-0001-6616-3484"]},"institutions":[{"id":"https://openalex.org/I2802125861","display_name":"Shriners Hospitals for Children - Canada","ror":"https://ror.org/01z1dtf94","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2802125861","https://openalex.org/I4210144267"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"F.H. Glorieux","raw_affiliation_strings":["Genetics Unit, Shriners Hospital for Children, Montreal, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Unit, Shriners Hospital for Children, Montreal, Quebec, Canada","institution_ids":["https://openalex.org/I2802125861"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025957125","display_name":"Rose Travers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802125861","display_name":"Shriners Hospitals for Children - Canada","ror":"https://ror.org/01z1dtf94","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2802125861","https://openalex.org/I4210144267"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"R. Travers","raw_affiliation_strings":["Genetics Unit, Shriners Hospital for Children, Montreal, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Unit, Shriners Hospital for Children, Montreal, Quebec, Canada","institution_ids":["https://openalex.org/I2802125861"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030580194","display_name":"Stuart Michael Sprague","orcid":"https://orcid.org/0000-0002-3330-0179","observed_orcids":["https://orcid.org/0000-0002-3330-0179"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I4210119687","display_name":"Evanston Hospital","ror":"https://ror.org/02nh10f55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1339509835","https://openalex.org/I40347166","https://openalex.org/I4210119687"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S.M. Sprague","raw_affiliation_strings":["Division of Nephrology, Evanston Hospital, Northwestern University Medical School, Evanston, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology, Evanston Hospital, Northwestern University Medical School, Evanston, Illinois","institution_ids":["https://openalex.org/I111979921","https://openalex.org/I4210119687"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":12.6415,"has_fulltext":false,"cited_by_count":401,"citation_normalized_percentile":{"value":0.99456922,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"5","issue":"1","first_page":"35","last_page":"51"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10359","display_name":"Dental Implant Techniques and Outcomes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bone-regeneration","display_name":"bone regeneration","score":0.9819999933242798},{"id":"https://openalex.org/keywords/bioresorbable-scaffolds","display_name":"bioresorbable scaffolds","score":0.9800000190734863},{"id":"https://openalex.org/keywords/scaffold-microarchitecture","display_name":"scaffold microarchitecture","score":0.8270000219345093},{"id":"https://openalex.org/keywords/critical-sized-calvarial-defect","display_name":"critical-size calvarial defect","score":0.8019999861717224},{"id":"https://openalex.org/keywords/poly-lactic-co-glycolic-acid","display_name":"poly(lactic-co-glycolic acid)","score":0.9240000247955322},{"id":"https://openalex.org/keywords/new-bone-formation","display_name":"new bone formation","score":0.8629999756813049},{"id":"https://openalex.org/keywords/osteoid","display_name":"osteoid","score":0.44699999690055847},{"id":"https://openalex.org/keywords/porosity","display_name":"porosity","score":0.5220000147819519},{"id":"https://openalex.org/keywords/pore-size","display_name":"pore size","score":0.7570000290870667},{"id":"https://openalex.org/keywords/rat-calvaria","display_name":"rat calvaria","score":0.7549999952316284}],"concepts":[{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.7822192907333374},{"id":"https://openalex.org/C107598950","wikidata":"https://www.wikidata.org/wiki/Q259864","display_name":"Microarchitecture","level":2,"score":0.6729096174240112},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.4717225432395935},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.42546117305755615},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.40775248408317566},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.3217872977256775},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1701185703277588},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.14776137471199036},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.14170345664024353}],"mesh":[{"descriptor_ui":"D000077182","descriptor_name":"Polylactic Acid-Polyglycolic Acid Copolymer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001698","descriptor_name":"Biomedical Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":true},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D001861","descriptor_name":"Bone Regeneration","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006406","descriptor_name":"Hematoma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008855","descriptor_name":"Microscopy, Electron, Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010012","descriptor_name":"Osteogenesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011100","descriptor_name":"Polyglycolic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012886","descriptor_name":"Skull","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018786","descriptor_name":"Bone Substitutes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019344","descriptor_name":"Lactic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020341","descriptor_name":"Absorbable Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1089/ten.1999.5.35","doi":"https://doi.org/10.1089/ten.1999.5.35","is_oa":false,"landing_page_url":"https://doi.org/10.1089/ten.1999.5.35","pdf_url":null,"source":{"id":"https://openalex.org/S164177214","display_name":"Tissue Engineering","issn_l":"1076-3279","issn":["1076-3279","1557-8690"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Engineering","raw_type":"journal-article"},{"id":"pmid:10207188","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10207188","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue engineering","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W54668368","https://openalex.org/W144827178","https://openalex.org/W576798506","https://openalex.org/W627897929","https://openalex.org/W1551519015","https://openalex.org/W1966606820","https://openalex.org/W1967264939","https://openalex.org/W1970036613","https://openalex.org/W1979869884","https://openalex.org/W1985656444","https://openalex.org/W1988264024","https://openalex.org/W1991144105","https://openalex.org/W1995037331","https://openalex.org/W2003337783","https://openalex.org/W2015917668","https://openalex.org/W2026360725","https://openalex.org/W2028637712","https://openalex.org/W2030157814","https://openalex.org/W2031982361","https://openalex.org/W2039583786","https://openalex.org/W2052766715","https://openalex.org/W2053115218","https://openalex.org/W2057454789","https://openalex.org/W2057724290","https://openalex.org/W2060904645","https://openalex.org/W2064565800","https://openalex.org/W2066520052","https://openalex.org/W2076869717","https://openalex.org/W2089273654","https://openalex.org/W2093313376","https://openalex.org/W2097111483","https://openalex.org/W2132905138","https://openalex.org/W2148714283","https://openalex.org/W2150858584","https://openalex.org/W2287360211","https://openalex.org/W2321752317","https://openalex.org/W2328747663"],"related_works":["https://openalex.org/W2120472195","https://openalex.org/W3100232185","https://openalex.org/W2558518533","https://openalex.org/W2030922043","https://openalex.org/W7164574353","https://openalex.org/W2080054593","https://openalex.org/W1596838913","https://openalex.org/W4291019878","https://openalex.org/W4413845433","https://openalex.org/W3196800693"],"abstract_inverted_index":{"Critical-sized":[0],"defects":[1,77],"(CSDs)":[2],"were":[3,60,80],"introduced":[4],"into":[5,24],"rat":[6],"calvaria":[7],"to":[8,82,165],"test":[9],"the":[10,21,72,75,120,141,152,156],"hypothesis":[11],"that":[12],"absorption":[13],"of":[14,46,54,74,131,158],"surrounding":[15],"blood,":[16],"marrow,":[17],"and":[18,50,56,69,87,98,122,128],"fluid":[19],"from":[20],"osseous":[22],"wound":[23],"a":[25,149],"bioabsorbable":[26],"polymer":[27],"matrix":[28],"with":[29,40,95,103],"unique":[30],"microarchitecture":[31,157],"can":[32],"induce":[33],"bone":[34,108,163],"formation":[35],"via":[36],"hematoma":[37,170],"stabilization.":[38,171],"Scaffolds":[39],"90%":[41],"porosity,":[42],"specific":[43],"surface":[44],"areas":[45],"approximately":[47],"10":[48],"m2/g,":[49],"median":[51],"pore":[52],"sizes":[53],"16":[55],"32":[57],"microm,":[58],"respectively,":[59],"fabricated":[61],"using":[62],"an":[63],"emulsion":[64],"freeze-drying":[65],"process.":[66],"Contact":[67],"radiography":[68],"radiomorphometry":[70],"revealed":[71,100],"size":[73],"initial":[76],"(50":[78],"mm2)":[79],"reduced":[81],"27":[83],"+/-":[84,89],"11":[85],"mm2":[86,91],"34":[88],"17":[90],"for":[92,160],"CSDs":[93],"treated":[94],"poly(D,L-lactide-co-glycolide).":[96],"Histology":[97],"histomorphometry":[99],"scaffolds":[101,159],"filled":[102],"significantly":[104],"more":[105,116],"de":[106],"novo":[107],"than":[109,118],"negative":[110,121],"controls":[111,124],"(p":[112,125],"<":[113,126],"0.":[114],"007),":[115],"osteoid":[117],"both":[119],"autograft":[123],"0.002),":[127],"small":[129],"masses":[130],"mineralized":[132],"tissue":[133],"(<":[134],"15":[135],"mm":[136],"in":[137,151,161],"diameter)":[138],"observed":[139],"within":[140],"scaffolds.":[142],"Based":[143],"on":[144,169],"these":[145],"findings,":[146],"we":[147],"propose":[148],"change":[150],"current":[153],"paradigm":[154],"regarding":[155],"vivo":[162],"regeneration":[164],"include":[166],"mechanisms":[167],"based":[168]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":19},{"year":2020,"cited_by_count":22},{"year":2019,"cited_by_count":16},{"year":2018,"cited_by_count":15},{"year":2017,"cited_by_count":21},{"year":2016,"cited_by_count":23},{"year":2015,"cited_by_count":14},{"year":2014,"cited_by_count":22},{"year":2013,"cited_by_count":24},{"year":2012,"cited_by_count":28}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}