{"id":"https://openalex.org/W2018542264","doi":"https://doi.org/10.1097/00000542-198805000-00004","title":"Does Chronic Treatment with Calcium Entry Blocking Drugs Reduce Perioperative Myocardial Ischemia?","display_name":"Does Chronic Treatment with Calcium Entry Blocking Drugs Reduce Perioperative Myocardial Ischemia?","publication_year":1988,"publication_date":"1988-05-01","ids":{"openalex":"https://openalex.org/W2018542264","doi":"https://doi.org/10.1097/00000542-198805000-00004","mag":"2018542264","pmid":"https://pubmed.ncbi.nlm.nih.gov/2897173"},"language":"en","primary_location":{"id":"doi:10.1097/00000542-198805000-00004","doi":"https://doi.org/10.1097/00000542-198805000-00004","is_oa":true,"landing_page_url":"https://doi.org/10.1097/00000542-198805000-00004","pdf_url":"https://pubs.asahq.org/anesthesiology/article-pdf/68/5/676/316154/0000542-198805000-00004.pdf","source":{"id":"https://openalex.org/S124035732","display_name":"Anesthesiology","issn_l":"0003-3022","issn":["0003-3022","1528-1175"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anesthesiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://pubs.asahq.org/anesthesiology/article-pdf/68/5/676/316154/0000542-198805000-00004.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084391963","display_name":"Stephen Slogoff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen Slogoff","raw_affiliation_strings":["Clinical Professor of Anesthesiology, University of Texas Health Science Center at Houston"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Professor of Anesthesiology, University of Texas Health Science Center at Houston","institution_ids":["https://openalex.org/I919571938"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113623662","display_name":"Arthur S. Keats","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arthur\u00a0S. Keats","raw_affiliation_strings":["Clinical Professor of Anesthesiology, University of Texas Health Science Center at Houston"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Professor of Anesthesiology, University of Texas Health Science Center at Houston","institution_ids":["https://openalex.org/I919571938"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I919571938"],"apc_list":null,"apc_paid":null,"fwci":12.377,"has_fulltext":false,"cited_by_count":136,"citation_normalized_percentile":{"value":0.99091629,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"68","issue":"5","first_page":"676","last_page":"680"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11930","display_name":"Cardiac, Anesthesia and Surgical Outcomes","score":0.9520999789237976,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11930","display_name":"Cardiac, Anesthesia and Surgical Outcomes","score":0.9520999789237976,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.01860000006854534,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.01080000028014183,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/calcium-channel-blockers","display_name":"calcium channel blockers","score":0.8399999737739563},{"id":"https://openalex.org/keywords/perioperative-myocardial-ischemia","display_name":"perioperative myocardial ischemia","score":0.9340000152587891},{"id":"https://openalex.org/keywords/coronary-artery-bypass-grafting","display_name":"coronary artery bypass grafting","score":0.8889999985694885},{"id":"https://openalex.org/keywords/nifedipine","display_name":"nifedipine","score":0.9620000123977661},{"id":"https://openalex.org/keywords/diltiazem","display_name":"diltiazem","score":1.0},{"id":"https://openalex.org/keywords/beta-blockers","display_name":"beta-blockers","score":0.8949999809265137},{"id":"https://openalex.org/keywords/tachycardia","display_name":"tachycardia","score":0.8080000281333923},{"id":"https://openalex.org/keywords/heart-rate","display_name":"heart rate","score":0.8379999995231628},{"id":"https://openalex.org/keywords/antianginal-therapy","display_name":"antianginal therapy","score":0.8479999899864197},{"id":"https://openalex.org/keywords/premedication","display_name":"premedication","score":0.3449999988079071}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9401564598083496},{"id":"https://openalex.org/C2776741139","wikidata":"https://www.wikidata.org/wiki/Q422229","display_name":"Diltiazem","level":3,"score":0.8059603571891785},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.7736679315567017},{"id":"https://openalex.org/C31174226","wikidata":"https://www.wikidata.org/wiki/Q64855140","display_name":"Perioperative","level":2,"score":0.6982969045639038},{"id":"https://openalex.org/C2779066535","wikidata":"https://www.wikidata.org/wiki/Q39111","display_name":"Nifedipine","level":3,"score":0.6558867692947388},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5831882953643799},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.5397473573684692},{"id":"https://openalex.org/C2780283014","wikidata":"https://www.wikidata.org/wiki/Q209583","display_name":"Tachycardia","level":2,"score":0.475220263004303},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.47459647059440613},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4267890751361847},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.4262140989303589},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3643028140068054}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000319","descriptor_name":"Adrenergic beta-Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001026","descriptor_name":"Coronary Artery Bypass","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D004110","descriptor_name":"Diltiazem","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D004110","descriptor_name":"Diltiazem","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007432","descriptor_name":"Intraoperative Period","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009543","descriptor_name":"Nifedipine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D009543","descriptor_name":"Nifedipine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/00000542-198805000-00004","doi":"https://doi.org/10.1097/00000542-198805000-00004","is_oa":true,"landing_page_url":"https://doi.org/10.1097/00000542-198805000-00004","pdf_url":"https://pubs.asahq.org/anesthesiology/article-pdf/68/5/676/316154/0000542-198805000-00004.pdf","source":{"id":"https://openalex.org/S124035732","display_name":"Anesthesiology","issn_l":"0003-3022","issn":["0003-3022","1528-1175"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anesthesiology","raw_type":"journal-article"},{"id":"pmid:2897173","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2897173","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anesthesiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1097/00000542-198805000-00004","doi":"https://doi.org/10.1097/00000542-198805000-00004","is_oa":true,"landing_page_url":"https://doi.org/10.1097/00000542-198805000-00004","pdf_url":"https://pubs.asahq.org/anesthesiology/article-pdf/68/5/676/316154/0000542-198805000-00004.pdf","source":{"id":"https://openalex.org/S124035732","display_name":"Anesthesiology","issn_l":"0003-3022","issn":["0003-3022","1528-1175"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anesthesiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2018542264.pdf","grobid_xml":"https://content.openalex.org/works/W2018542264.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2044277186","https://openalex.org/W2168752714","https://openalex.org/W2324669379","https://openalex.org/W4256244264","https://openalex.org/W1971798228","https://openalex.org/W1988878044","https://openalex.org/W2133514624","https://openalex.org/W2991788444","https://openalex.org/W1965927730","https://openalex.org/W2087952663"],"abstract_inverted_index":{"To":[0],"examine":[1],"the":[2,17,23,85,132,212],"role":[3],"of":[4,19,35,99,107,146,168,175,189,214,226],"chronic":[5],"calcium":[6,42,57,122,230],"entry":[7,43,58,123,231],"blocking":[8,44,62,67,124,139,180,232],"drug":[9],"administration":[10],"on":[11,150],"perioperative":[12],"myocardial":[13],"ischemia":[14,75,101,183,215],"and,":[15],"specifically,":[16],"frequency":[18],"hemodynamically":[20],"unrelated":[21],"ischemia,":[22,227],"authors":[24],"studied":[25],"444":[26],"patients":[27,38,120,171,228],"undergoing":[28],"coronary":[29],"artery":[30],"bypass":[31],"operations.":[32],"Before":[33],"induction":[34],"anesthesia,":[36,157],"119":[37],"who":[39],"chronically":[40],"took":[41],"drugs":[45,68,140,233],"received":[46,56,65,72],"nifedipine":[47],"20":[48],"mg":[49,53],"or":[50,110,203],"diltiazem":[51],"60":[52],"orally,":[54],"74":[55],"and":[59,70,92,155],"beta":[60,66,137,179],"adrenergic":[61,138],"drugs,":[63],"71":[64],"only,":[69],"180":[71],"neither.":[73],"New":[74],"occurred":[76],"in":[77,119,131,165,187],"208":[78],"(46.8%)":[79],"patients;":[80],"55":[81],"at":[82],"arrival":[83,151],"to":[84,105,173,205,223],"operating":[86],"room,":[87],"86":[88],"only":[89,166,234],"after":[90],"induction,":[91],"67":[93],"separately":[94],"during":[95,156,185],"both":[96,149],"periods.":[97],"Two-thirds":[98],"all":[100,190,224],"was":[102,115,194,200],"not":[103,116,177,217],"related":[104],"extremes":[106],"heart":[108,160,198,210],"rate":[109,161,199],"blood":[111],"pressure;":[112],"this":[113],"type":[114],"less":[117,129,147],"frequent":[118],"receiving":[121,136,178,229,239],"drugs.":[125,181],"Ischemia":[126],"did":[127,216],"occur":[128],"frequently":[130],"two":[133],"patient":[134],"groups":[135],"(34%":[141],"vs.":[142,153],"53%),":[143],"a":[144],"result":[145],"tachycardia":[148],"(3.4%":[152],"15.4%)":[154],"when":[158,197],"peak":[159],"exceeded":[162],"109":[163],"bpm":[164],"one":[167],"145":[169],"beta-blocked":[170],"compared":[172],"29":[174],"299":[176],"While":[182],"appeared":[184],"anesthesia":[186],"34.5%":[188],"patients,":[191],"its":[192],"incidence":[193,213],"doubled":[195],"(63%)":[196],"greater":[201],"than":[202],"equal":[204],"110":[206],"bpm.":[207],"At":[208],"lower":[209],"rates,":[211],"differ":[218],"among":[219],"groups.":[220],"With":[221],"respect":[222],"types":[225],"were":[235],"indistinguishable":[236],"from":[237],"those":[238],"no":[240],"antianginal":[241],"therapy.(ABSTRACT":[242],"TRUNCATED":[243],"AT":[244],"250":[245],"WORDS)":[246]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}