{"id":"https://openalex.org/W2018379650","doi":"https://doi.org/10.1016/s0161-6420(92)32025-1","title":"Effect of Topical Mitomycin C on Glaucoma Filtration Surgery in Monkeys","display_name":"Effect of Topical Mitomycin C on Glaucoma Filtration Surgery in Monkeys","publication_year":1992,"publication_date":"1992-01-01","ids":{"openalex":"https://openalex.org/W2018379650","doi":"https://doi.org/10.1016/s0161-6420(92)32025-1","mag":"2018379650","pmid":"https://pubmed.ncbi.nlm.nih.gov/1741126"},"language":"en","primary_location":{"id":"doi:10.1016/s0161-6420(92)32025-1","doi":"https://doi.org/10.1016/s0161-6420(92)32025-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0161-6420(92)32025-1","pdf_url":null,"source":{"id":"https://openalex.org/S207341048","display_name":"Ophthalmology","issn_l":"0161-6420","issn":["0161-6420","1549-4713"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ophthalmology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/s0161-6420(92)32025-1","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010480125","display_name":"Louis Robert Pasquale","orcid":"https://orcid.org/0000-0002-5835-3496","observed_orcids":["https://orcid.org/0000-0002-5835-3496"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Louis R. Pasquale","raw_affiliation_strings":["Glaucoma Service, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD 21205","From the Glaucoma Service, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glaucoma Service, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD 21205","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"From the Glaucoma Service, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073938565","display_name":"Diane Thibault","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diane Thibault","raw_affiliation_strings":["From the Glaucoma Service, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Glaucoma Service, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019211966","display_name":"Mary Ellen Pease","orcid":"https://orcid.org/0000-0002-1368-1234","observed_orcids":["https://orcid.org/0000-0002-1368-1234"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Ellen Dorman-Pease","raw_affiliation_strings":["From the Glaucoma Service, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Glaucoma Service, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042154323","display_name":"Harry A. Quigley","orcid":"https://orcid.org/0000-0003-0095-8756","observed_orcids":["https://orcid.org/0000-0003-0095-8756"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harry A. Quigley","raw_affiliation_strings":["From the Glaucoma Service, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Glaucoma Service, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019049183","display_name":"HENRY D. JAMPEL","orcid":"https://orcid.org/0000-0003-0403-9423","observed_orcids":["https://orcid.org/0000-0003-0403-9423"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Henry D. Jampel","raw_affiliation_strings":["From the Glaucoma Service, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Glaucoma Service, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5019049183"],"corresponding_institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"],"apc_list":{"value":4990,"currency":"USD","value_usd":4990},"apc_paid":{"value":4990,"currency":"USD","value_usd":4990},"fwci":17.4977,"has_fulltext":false,"cited_by_count":90,"citation_normalized_percentile":{"value":0.99724167,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"99","issue":"1","first_page":"14","last_page":"18"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11291","display_name":"Intraocular Surgery and Lenses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitomycin-c","display_name":"mitomycin C","score":0.9860000014305115},{"id":"https://openalex.org/keywords/glaucoma-filtering-surgery","display_name":"glaucoma filtration surgery","score":0.9800000190734863},{"id":"https://openalex.org/keywords/trabeculectomy","display_name":"trabeculectomy","score":0.8820000290870667},{"id":"https://openalex.org/keywords/sclerostomy","display_name":"sclerostomy","score":0.8119999766349792},{"id":"https://openalex.org/keywords/argon-laser-trabeculoplasty","display_name":"argon laser trabeculoplasty","score":0.8679999709129333},{"id":"https://openalex.org/keywords/elevated-intraocular-pressure","display_name":"intraocular pressure elevation","score":0.824999988079071},{"id":"https://openalex.org/keywords/surgical-wound-healing","display_name":"surgical wound healing","score":0.8610000014305115},{"id":"https://openalex.org/keywords/ocular-toxicity","display_name":"ocular toxicity","score":0.6990000009536743},{"id":"https://openalex.org/keywords/monkey-model","display_name":"monkey model","score":0.46799999475479126}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9300065040588379},{"id":"https://openalex.org/C2779338040","wikidata":"https://www.wikidata.org/wiki/Q19856779","display_name":"Mitomycin C","level":2,"score":0.9041551351547241},{"id":"https://openalex.org/C2777824320","wikidata":"https://www.wikidata.org/wiki/Q3177088","display_name":"Trabeculectomy","level":3,"score":0.7065773010253906},{"id":"https://openalex.org/C2778527774","wikidata":"https://www.wikidata.org/wiki/Q159701","display_name":"Glaucoma","level":2,"score":0.6926435828208923},{"id":"https://openalex.org/C2781092963","wikidata":"https://www.wikidata.org/wiki/Q650050","display_name":"Intraocular pressure","level":2,"score":0.6520830392837524},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5983027815818787},{"id":"https://openalex.org/C2776766258","wikidata":"https://www.wikidata.org/wiki/Q5567291","display_name":"Glaucoma surgery","level":3,"score":0.5225379467010498},{"id":"https://openalex.org/C2778996431","wikidata":"https://www.wikidata.org/wiki/Q4849997","display_name":"Balanced salt solution","level":2,"score":0.48400112986564636},{"id":"https://openalex.org/C2776228307","wikidata":"https://www.wikidata.org/wiki/Q4925763","display_name":"Bleb (medicine)","level":4,"score":0.45585688948631287},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.45507776737213135},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000287","descriptor_name":"Administration, Topical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000287","descriptor_name":"Administration, Topical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000287","descriptor_name":"Administration, Topical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000869","descriptor_name":"Anterior Eye Segment","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000869","descriptor_name":"Anterior Eye Segment","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000869","descriptor_name":"Anterior Eye Segment","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005901","descriptor_name":"Glaucoma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D005901","descriptor_name":"Glaucoma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D005901","descriptor_name":"Glaucoma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D005901","descriptor_name":"Glaucoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005901","descriptor_name":"Glaucoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005901","descriptor_name":"Glaucoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005901","descriptor_name":"Glaucoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D005901","descriptor_name":"Glaucoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D005901","descriptor_name":"Glaucoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D007429","descriptor_name":"Intraocular Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007429","descriptor_name":"Intraocular Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007429","descriptor_name":"Intraocular Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007430","descriptor_name":"Intraoperative Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007430","descriptor_name":"Intraoperative Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007430","descriptor_name":"Intraoperative Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008252","descriptor_name":"Macaca fascicularis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008252","descriptor_name":"Macaca fascicularis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008252","descriptor_name":"Macaca fascicularis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013524","descriptor_name":"Surgical Flaps","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013524","descriptor_name":"Surgical Flaps","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013524","descriptor_name":"Surgical Flaps","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014130","descriptor_name":"Trabeculectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014130","descriptor_name":"Trabeculectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014130","descriptor_name":"Trabeculectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016685","descriptor_name":"Mitomycin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016685","descriptor_name":"Mitomycin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016685","descriptor_name":"Mitomycin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053685","descriptor_name":"Laser Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053685","descriptor_name":"Laser Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053685","descriptor_name":"Laser Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0161-6420(92)32025-1","doi":"https://doi.org/10.1016/s0161-6420(92)32025-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0161-6420(92)32025-1","pdf_url":null,"source":{"id":"https://openalex.org/S207341048","display_name":"Ophthalmology","issn_l":"0161-6420","issn":["0161-6420","1549-4713"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ophthalmology","raw_type":"journal-article"},{"id":"pmid:1741126","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1741126","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ophthalmology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s0161-6420(92)32025-1","doi":"https://doi.org/10.1016/s0161-6420(92)32025-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0161-6420(92)32025-1","pdf_url":null,"source":{"id":"https://openalex.org/S207341048","display_name":"Ophthalmology","issn_l":"0161-6420","issn":["0161-6420","1549-4713"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ophthalmology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.7200000286102295,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3033057233","display_name":null,"funder_award_id":"#EY01765","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G309658470","display_name":null,"funder_award_id":"EY 02120","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G5241073741","display_name":null,"funder_award_id":"EY 07047","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G5831246869","display_name":"P30 Wilmer Core Grant for Vision Research","funder_award_id":"P30EY001765","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W11830441","https://openalex.org/W15357752","https://openalex.org/W23721054","https://openalex.org/W121069851","https://openalex.org/W1977149291","https://openalex.org/W1989215939","https://openalex.org/W1997487881","https://openalex.org/W1998094324","https://openalex.org/W2008306097","https://openalex.org/W2034827398","https://openalex.org/W2039840402","https://openalex.org/W2040100388","https://openalex.org/W2051126611","https://openalex.org/W2091728997","https://openalex.org/W2111205036","https://openalex.org/W2157627620","https://openalex.org/W2407502585","https://openalex.org/W2424563390","https://openalex.org/W3042793008","https://openalex.org/W4251855411"],"related_works":["https://openalex.org/W2235605628","https://openalex.org/W2037537056","https://openalex.org/W1973773821","https://openalex.org/W1998094324","https://openalex.org/W1974861617","https://openalex.org/W2137261565","https://openalex.org/W2020906015","https://openalex.org/W2417242011","https://openalex.org/W2040563120","https://openalex.org/W2413795969"],"abstract_inverted_index":{"In":[0],"this":[1],"study,":[2],"an":[3],"experimental":[4],"model":[5],"of":[6,19,25,38,45,63,73,124,140],"glaucoma":[7],"filtration":[8,152],"surgery":[9,107,153],"was":[10,68,93,114],"used":[11],"to":[12,31,51],"evaluate":[13],"the":[14,32,61],"clinical":[15],"and":[16,108,131],"histologic":[17],"effects":[18],"a":[20,144],"single":[21,137],"intraoperative":[22,138],"topical":[23,53,87],"application":[24,139],"mitomycin":[26,54,78,120,125,141],"C.":[27,121],"Argon":[28],"laser":[29],"treatment":[30],"trabecular":[33],"meshwork":[34],"produced":[35],"sustained":[36],"elevation":[37],"intraocular":[39],"pressure":[40],"in":[41,71,96,100,116,154],"monkeys.":[42,155],"Eight":[43],"eyes":[44,75,84,102,117,127],"four":[46,72],"animals":[47],"were":[48],"randomly":[49],"assigned":[50],"receive":[52],"C":[55,79,92,142],"or":[56],"balanced":[57,88],"salt":[58,89],"solution":[59],"at":[60],"time":[62],"full-thickness":[64],"sclerostomy.":[65],"Surgical":[66],"success":[67,99],"substantially":[69],"increased":[70],"five":[74],"that":[76,85,103],"received":[77,86],"when":[80],"compared":[81],"with":[82,119],"three":[83],"solution.":[90],"Mitomycin":[91],"also":[94],"effective":[95],"prolonging":[97],"surgical":[98],"two":[101],"had":[104],"previously":[105],"undergone":[106],"failed.":[109],"No":[110],"significant":[111],"ocular":[112],"toxicity":[113],"observed":[115],"treated":[118],"Histologic":[122],"examination":[123],"C-treated":[126],"showed":[128],"patent":[129],"sclerostomies":[130],"hypocellular,":[132],"well-formed":[133],"bleb":[134],"cavities.":[135],"A":[136],"has":[143],"marked":[145],"effect":[146],"on":[147],"postoperative":[148],"wound":[149],"healing":[150],"after":[151]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2016-06-24T00:00:00"}