{"id":"https://openalex.org/W2018365645","doi":"https://doi.org/10.1159/000179912","title":"Fanconi Syndrome with Renal Tubular Acidosis and Light Chain Proteinuria","display_name":"Fanconi Syndrome with Renal Tubular Acidosis and Light Chain Proteinuria","publication_year":2008,"publication_date":"2008-11-26","ids":{"openalex":"https://openalex.org/W2018365645","doi":"https://doi.org/10.1159/000179912","mag":"2018365645","pmid":"https://pubmed.ncbi.nlm.nih.gov/5155597"},"language":"en","primary_location":{"id":"doi:10.1159/000179912","doi":"https://doi.org/10.1159/000179912","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000179912","pdf_url":null,"source":{"id":"https://openalex.org/S4393917655","display_name":"The Nephron journals/Nephron journals","issn_l":"1660-8151","issn":["1660-8151","2235-3186"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephron","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103413531","display_name":"Barry R. Walker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B.R. Walker","raw_affiliation_strings":["Presbyterian-University of Pennsylvania Medical Center, Philadelphia, Pa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Presbyterian-University of Pennsylvania Medical Center, Philadelphia, Pa","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111377116","display_name":"Fred Alexander","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"F. Alexander","raw_affiliation_strings":["Presbyterian-University of Pennsylvania Medical Center, Philadelphia, Pa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Presbyterian-University of Pennsylvania Medical Center, Philadelphia, Pa","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048897716","display_name":"Ph.J. Tannenbaum","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ph.J. Tannenbaum","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6753,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.6868974,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"8","issue":"1","first_page":"103","last_page":"107"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":0.4514000117778778,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":0.4514000117778778,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12840","display_name":"Renal function and acid-base balance","score":0.20090000331401825,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.062300000339746475,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fanconi-syndrome","display_name":"Fanconi syndrome","score":1.0},{"id":"https://openalex.org/keywords/renal-tubular-acidosis","display_name":"renal tubular acidosis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/sjogren-s-syndrome","display_name":"Sj\u00f6gren's syndrome","score":0.9679999947547913},{"id":"https://openalex.org/keywords/monoclonal-gammopathy","display_name":"monoclonal gammopathy","score":0.8059999942779541},{"id":"https://openalex.org/keywords/gamma-globulin","display_name":"gamma globulin","score":0.6830000281333923},{"id":"https://openalex.org/keywords/triamterene","display_name":"triamterene","score":0.718999981880188},{"id":"https://openalex.org/keywords/electrolyte-imbalance","display_name":"electrolyte imbalance","score":0.4560000002384186}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9081103205680847},{"id":"https://openalex.org/C2781079508","wikidata":"https://www.wikidata.org/wiki/Q1516211","display_name":"Renal tubular acidosis","level":3,"score":0.7864216566085815},{"id":"https://openalex.org/C2779561371","wikidata":"https://www.wikidata.org/wiki/Q570197","display_name":"Proteinuria","level":3,"score":0.7708396911621094},{"id":"https://openalex.org/C2779026464","wikidata":"https://www.wikidata.org/wiki/Q1179460","display_name":"Fanconi syndrome","level":3,"score":0.7432979345321655},{"id":"https://openalex.org/C2777622974","wikidata":"https://www.wikidata.org/wiki/Q221520","display_name":"Triamterene","level":4,"score":0.6502425670623779},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.582472026348114},{"id":"https://openalex.org/C2778553927","wikidata":"https://www.wikidata.org/wiki/Q185089","display_name":"Acidosis","level":2,"score":0.5345709919929504},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.5271615386009216},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.492076575756073},{"id":"https://openalex.org/C2781214132","wikidata":"https://www.wikidata.org/wiki/Q1136213","display_name":"Glycosuria","level":3,"score":0.4603199362754822},{"id":"https://openalex.org/C2776356786","wikidata":"https://www.wikidata.org/wiki/Q1048573","display_name":"Tubulopathy","level":3,"score":0.45463910698890686},{"id":"https://openalex.org/C2779246250","wikidata":"https://www.wikidata.org/wiki/Q1598200","display_name":"Metabolic acidosis","level":2,"score":0.4376479387283325},{"id":"https://openalex.org/C2776598079","wikidata":"https://www.wikidata.org/wiki/Q2896802","display_name":"Distal renal tubular acidosis","level":3,"score":0.41192519664764404},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3631436824798584},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.2977287173271179},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.19319525361061096},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.07090508937835693},{"id":"https://openalex.org/C2780361556","wikidata":"https://www.wikidata.org/wiki/Q423930","display_name":"Hydrochlorothiazide","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000141","descriptor_name":"Acidosis, Renal Tubular","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D000141","descriptor_name":"Acidosis, Renal Tubular","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001797","descriptor_name":"Blood Protein Electrophoresis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005198","descriptor_name":"Fanconi Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006942","descriptor_name":"Hypergammaglobulinemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D007122","descriptor_name":"Immunoelectrophoresis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007128","descriptor_name":"Immunoglobulin Fragments","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007128","descriptor_name":"Immunoglobulin Fragments","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D007136","descriptor_name":"Immunoglobulins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007136","descriptor_name":"Immunoglobulins","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D007677","descriptor_name":"Kidney Function Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007686","descriptor_name":"Kidney Tubules, Distal","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D007687","descriptor_name":"Kidney Tubules, Proximal","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D011507","descriptor_name":"Proteinuria","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D012859","descriptor_name":"Sjogren's Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1159/000179912","doi":"https://doi.org/10.1159/000179912","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000179912","pdf_url":null,"source":{"id":"https://openalex.org/S4393917655","display_name":"The Nephron journals/Nephron journals","issn_l":"1660-8151","issn":["1660-8151","2235-3186"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephron","raw_type":"journal-article"},{"id":"pmid:5155597","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5155597","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephron","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2032563659","https://openalex.org/W6991089185","https://openalex.org/W1974226086","https://openalex.org/W2300462894","https://openalex.org/W2414021283","https://openalex.org/W3167859462","https://openalex.org/W2411563650","https://openalex.org/W2048063421","https://openalex.org/W2419532686","https://openalex.org/W2427850506"],"abstract_inverted_index":{"A":[0],"patient":[1],"is":[2],"described":[3],"with":[4],"Sj\u00f6gren\u2019s":[5],"syndrome,":[6,9],"the":[7],"Fanconi":[8],"proximal":[10],"and":[11,16,21,25,34],"distal":[12],"renal":[13],"tubular":[14],"acidosis,":[15],"elevations":[17],"of":[18],"both":[19],"blood":[20,33],"urine":[22,35],"gamma":[23],"globulin":[24],"light":[26],"chains.":[27],"Triamterene":[28],"had":[29],"no":[30],"effect":[31],"on":[32],"electrolytes.":[36]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}