{"id":"https://openalex.org/W2018357540","doi":"https://doi.org/10.1203/00006450-197406000-00001","title":"The Renin-Angiotensin System in the Fetal Lamb","display_name":"The Renin-Angiotensin System in the Fetal Lamb","publication_year":1974,"publication_date":"1974-06-01","ids":{"openalex":"https://openalex.org/W2018357540","doi":"https://doi.org/10.1203/00006450-197406000-00001","mag":"2018357540","pmid":"https://pubmed.ncbi.nlm.nih.gov/4365212"},"language":"en","primary_location":{"id":"doi:10.1203/00006450-197406000-00001","doi":"https://doi.org/10.1203/00006450-197406000-00001","is_oa":false,"landing_page_url":"https://doi.org/10.1203/00006450-197406000-00001","pdf_url":null,"source":{"id":"https://openalex.org/S167664057","display_name":"Pediatric Research","issn_l":"0031-3998","issn":["0031-3998","1530-0447"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109983911","display_name":"F. Smith","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fred G Smith","raw_affiliation_strings":["Department of Pediatrics, Department of Surgery/Urology, Department of Biology, Department of Anesthesiology and Department of Obstetrics and Gynecology, Gwynne Hazen Cherry Renal Research Laboratory, University of California at Los Angeles, School of Medicine, Los Angeles, California, USA","University of California, Los Angeles, Los Angeles, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Department of Surgery/Urology, Department of Biology, Department of Anesthesiology and Department of Obstetrics and Gynecology, Gwynne Hazen Cherry Renal Research Laboratory, University of California at Los Angeles, School of Medicine, Los Angeles, California, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"University of California, Los Angeles, Los Angeles, United States","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086769710","display_name":"Andrei N. Lupu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrei N Lupu","raw_affiliation_strings":["Department of Pediatrics, Department of Surgery/Urology, Department of Biology, Department of Anesthesiology and Department of Obstetrics and Gynecology, Gwynne Hazen Cherry Renal Research Laboratory, University of California at Los Angeles, School of Medicine, Los Angeles, California, USA","University of California, Los Angeles, Los Angeles, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Department of Surgery/Urology, Department of Biology, Department of Anesthesiology and Department of Obstetrics and Gynecology, Gwynne Hazen Cherry Renal Research Laboratory, University of California at Los Angeles, School of Medicine, Los Angeles, California, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"University of California, Los Angeles, Los Angeles, United States","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109561048","display_name":"Luciano Barajas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luciano Barajas","raw_affiliation_strings":["Department of Pediatrics, Department of Surgery/Urology, Department of Biology, Department of Anesthesiology and Department of Obstetrics and Gynecology, Gwynne Hazen Cherry Renal Research Laboratory, University of California at Los Angeles, School of Medicine, Los Angeles, California, USA","University of California, Los Angeles, Los Angeles, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Department of Surgery/Urology, Department of Biology, Department of Anesthesiology and Department of Obstetrics and Gynecology, Gwynne Hazen Cherry Renal Research Laboratory, University of California at Los Angeles, School of Medicine, Los Angeles, California, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"University of California, Los Angeles, Los Angeles, United States","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113477594","display_name":"Robert Otto Bauer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Bauer","raw_affiliation_strings":["Department of Pediatrics, Department of Surgery/Urology, Department of Biology, Department of Anesthesiology and Department of Obstetrics and Gynecology, Gwynne Hazen Cherry Renal Research Laboratory, University of California at Los Angeles, School of Medicine, Los Angeles, California, USA","University of California, Los Angeles, Los Angeles, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Department of Surgery/Urology, Department of Biology, Department of Anesthesiology and Department of Obstetrics and Gynecology, Gwynne Hazen Cherry Renal Research Laboratory, University of California at Los Angeles, School of Medicine, Los Angeles, California, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"University of California, Los Angeles, Los Angeles, United States","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064521833","display_name":"RICHARD A. BASHORE","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard A Bashore","raw_affiliation_strings":["Department of Pediatrics, Department of Surgery/Urology, Department of Biology, Department of Anesthesiology and Department of Obstetrics and Gynecology, Gwynne Hazen Cherry Renal Research Laboratory, University of California at Los Angeles, School of Medicine, Los Angeles, California, USA","University of California, Los Angeles, Los Angeles, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Department of Surgery/Urology, Department of Biology, Department of Anesthesiology and Department of Obstetrics and Gynecology, Gwynne Hazen Cherry Renal Research Laboratory, University of California at Los Angeles, School of Medicine, Los Angeles, California, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"University of California, Los Angeles, Los Angeles, United States","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I161318765"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":3.8704,"has_fulltext":true,"cited_by_count":73,"citation_normalized_percentile":{"value":0.92297365,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"8","issue":"6","first_page":"611","last_page":"620"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.00930000003427267,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/renin-angiotensin-system","display_name":"renin-angiotensin system","score":0.996999979019165},{"id":"https://openalex.org/keywords/fetal-sheep","display_name":"fetal sheep","score":0.7110000252723694},{"id":"https://openalex.org/keywords/plasma-renin-activity","display_name":"plasma renin activity","score":0.8830000162124634},{"id":"https://openalex.org/keywords/fetal-kidney","display_name":"fetal kidney","score":0.6549999713897705},{"id":"https://openalex.org/keywords/juxtaglomerular-apparatus","display_name":"juxtaglomerular apparatus","score":0.968999981880188},{"id":"https://openalex.org/keywords/aortic-constriction","display_name":"aortic constriction","score":0.8610000014305115},{"id":"https://openalex.org/keywords/gestational-age","display_name":"gestational age","score":0.7900000214576721},{"id":"https://openalex.org/keywords/fetal-development","display_name":"fetal development","score":0.5839999914169312},{"id":"https://openalex.org/keywords/renal-autoregulation","display_name":"renal autoregulation","score":0.5879999995231628}],"concepts":[{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.8093738555908203},{"id":"https://openalex.org/C138976137","wikidata":"https://www.wikidata.org/wiki/Q7201790","display_name":"Plasma renin activity","level":4,"score":0.7975245714187622},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6215949654579163},{"id":"https://openalex.org/C201614185","wikidata":"https://www.wikidata.org/wiki/Q396833","display_name":"In utero","level":4,"score":0.5910623073577881},{"id":"https://openalex.org/C198710026","wikidata":"https://www.wikidata.org/wiki/Q898218","display_name":"Renin\u2013angiotensin system","level":3,"score":0.5795201063156128},{"id":"https://openalex.org/C174940676","wikidata":"https://www.wikidata.org/wiki/Q495626","display_name":"Constriction","level":2,"score":0.5595163702964783},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.5403938293457031},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46029743552207947},{"id":"https://openalex.org/C37557685","wikidata":"https://www.wikidata.org/wiki/Q1896673","display_name":"Blood volume","level":2,"score":0.45958414673805237},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.42404115200042725},{"id":"https://openalex.org/C2991747820","wikidata":"https://www.wikidata.org/wiki/Q1896673","display_name":"Plasma volume","level":2,"score":0.4184548258781433},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.2743532657623291},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.17674994468688965},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11727067828178406},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000136","descriptor_name":"Acid-Base Equilibrium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000804","descriptor_name":"Angiotensin II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001769","descriptor_name":"Blood","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001810","descriptor_name":"Blood Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001831","descriptor_name":"Body Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005333","descriptor_name":"Fetus","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D005333","descriptor_name":"Fetus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007606","descriptor_name":"Juxtaglomerular Apparatus","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D007606","descriptor_name":"Juxtaglomerular Apparatus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008026","descriptor_name":"Ligation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010313","descriptor_name":"Partial Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011674","descriptor_name":"Pulse","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012083","descriptor_name":"Renin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012083","descriptor_name":"Renin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1203/00006450-197406000-00001","doi":"https://doi.org/10.1203/00006450-197406000-00001","is_oa":false,"landing_page_url":"https://doi.org/10.1203/00006450-197406000-00001","pdf_url":null,"source":{"id":"https://openalex.org/S167664057","display_name":"Pediatric Research","issn_l":"0031-3998","issn":["0031-3998","1530-0447"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Research","raw_type":"journal-article"},{"id":"pmid:4365212","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4365212","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.46810001134872437,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W199424746","https://openalex.org/W1586912476","https://openalex.org/W2002266862","https://openalex.org/W2009088193","https://openalex.org/W2052832924","https://openalex.org/W2064598870","https://openalex.org/W2066200838","https://openalex.org/W2069986440","https://openalex.org/W2128055353","https://openalex.org/W2150348610","https://openalex.org/W2327514967","https://openalex.org/W2398033304","https://openalex.org/W2405902554","https://openalex.org/W2410605068","https://openalex.org/W2411881329","https://openalex.org/W2463357427","https://openalex.org/W2464358058","https://openalex.org/W4242506331"],"related_works":["https://openalex.org/W2072730012","https://openalex.org/W1992720174","https://openalex.org/W1967034403","https://openalex.org/W2003701057","https://openalex.org/W1968289470","https://openalex.org/W2137119168","https://openalex.org/W152026614","https://openalex.org/W2186802941","https://openalex.org/W2118581224","https://openalex.org/W2420897666"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}