{"id":"https://openalex.org/W2018307646","doi":"https://doi.org/10.1083/jcb.120.5.1187","title":"Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).","display_name":"Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).","publication_year":1993,"publication_date":"1993-03-01","ids":{"openalex":"https://openalex.org/W2018307646","doi":"https://doi.org/10.1083/jcb.120.5.1187","mag":"2018307646","pmid":"https://pubmed.ncbi.nlm.nih.gov/8436590","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2119720"},"language":"en","primary_location":{"id":"doi:10.1083/jcb.120.5.1187","doi":"https://doi.org/10.1083/jcb.120.5.1187","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.120.5.1187","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2018307646"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2119720/pdf/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006019437","display_name":"Kiyohiko Kishi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I65837984","display_name":"Kobe University","ror":"https://ror.org/03tgsfw79","country_code":"JP","type":"education","lineage":["https://openalex.org/I65837984"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K Kishi","raw_affiliation_strings":["Department of Biochemistry, Kobe University School of Medicine, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Kobe University School of Medicine, Japan","institution_ids":["https://openalex.org/I65837984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101587669","display_name":"Takuya Sasaki","orcid":"https://orcid.org/0000-0002-0576-7142","observed_orcids":["https://orcid.org/0000-0002-0576-7142"]},"institutions":[{"id":"https://openalex.org/I65837984","display_name":"Kobe University","ror":"https://ror.org/03tgsfw79","country_code":"JP","type":"education","lineage":["https://openalex.org/I65837984"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T Sasaki","raw_affiliation_strings":["Department of Biochemistry, Kobe University School of Medicine, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Kobe University School of Medicine, Japan","institution_ids":["https://openalex.org/I65837984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035549362","display_name":"Shinya Kuroda","orcid":"https://orcid.org/0000-0001-5059-8299","observed_orcids":["https://orcid.org/0000-0001-5059-8299"]},"institutions":[{"id":"https://openalex.org/I65837984","display_name":"Kobe University","ror":"https://ror.org/03tgsfw79","country_code":"JP","type":"education","lineage":["https://openalex.org/I65837984"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"S Kuroda","raw_affiliation_strings":["Department of Biochemistry, Kobe University School of Medicine, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Kobe University School of Medicine, Japan","institution_ids":["https://openalex.org/I65837984"]}]},{"author_position":"middle","author":{"id":null,"display_name":"T Itoh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I65837984","display_name":"Kobe University","ror":"https://ror.org/03tgsfw79","country_code":"JP","type":"education","lineage":["https://openalex.org/I65837984"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T Itoh","raw_affiliation_strings":["Department of Biochemistry, Kobe University School of Medicine, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Kobe University School of Medicine, Japan","institution_ids":["https://openalex.org/I65837984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042331400","display_name":"Yoshimi Takai","orcid":"https://orcid.org/0000-0003-1338-1327","observed_orcids":["https://orcid.org/0000-0003-1338-1327"]},"institutions":[{"id":"https://openalex.org/I65837984","display_name":"Kobe University","ror":"https://ror.org/03tgsfw79","country_code":"JP","type":"education","lineage":["https://openalex.org/I65837984"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y Takai","raw_affiliation_strings":["Department of Biochemistry, Kobe University School of Medicine, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Kobe University School of Medicine, Japan","institution_ids":["https://openalex.org/I65837984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I65837984"],"apc_list":null,"apc_paid":null,"fwci":7.19,"has_fulltext":true,"cited_by_count":368,"citation_normalized_percentile":{"value":0.98118649,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"120","issue":"5","first_page":"1187","last_page":"1195"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.6151999831199646,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.6151999831199646,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.34279999136924744,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.00860000029206276,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rhogdi","display_name":"RhoGDI","score":0.9810000061988831},{"id":"https://openalex.org/keywords/rhoa","display_name":"RhoA","score":0.6110000014305115},{"id":"https://openalex.org/keywords/cytokinesis","display_name":"cytokinesis","score":0.8080000281333923},{"id":"https://openalex.org/keywords/actomyosin","display_name":"actomyosin","score":0.7170000076293945},{"id":"https://openalex.org/keywords/xenopus-embryo","display_name":"Xenopus embryo","score":0.7620000243186951},{"id":"https://openalex.org/keywords/adp-ribosylation","display_name":"ADP-ribosylation","score":0.9559999704360962},{"id":"https://openalex.org/keywords/furrow-formation","display_name":"furrow formation","score":0.7129999995231628},{"id":"https://openalex.org/keywords/contractile-ring","display_name":"contractile ring","score":0.9380000233650208},{"id":"https://openalex.org/keywords/small-gtpases","display_name":"small GTPases","score":0.8399999737739563}],"concepts":[{"id":"https://openalex.org/C2777093181","wikidata":"https://www.wikidata.org/wiki/Q15331450","display_name":"RHOA","level":3,"score":0.7835231423377991},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7676398754119873},{"id":"https://openalex.org/C2779535977","wikidata":"https://www.wikidata.org/wiki/Q1342298","display_name":"Xenopus","level":3,"score":0.6792391538619995},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.609300971031189},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.5639317035675049},{"id":"https://openalex.org/C45472230","wikidata":"https://www.wikidata.org/wiki/Q1447198","display_name":"Cytokinesis","level":4,"score":0.5626388788223267},{"id":"https://openalex.org/C85813293","wikidata":"https://www.wikidata.org/wiki/Q188909","display_name":"Cell division","level":3,"score":0.5575076937675476},{"id":"https://openalex.org/C62525196","wikidata":"https://www.wikidata.org/wiki/Q3311945","display_name":"Microinjection","level":2,"score":0.5318892598152161},{"id":"https://openalex.org/C85771745","wikidata":"https://www.wikidata.org/wiki/Q5514732","display_name":"GTP-binding protein regulators","level":4,"score":0.5067210793495178},{"id":"https://openalex.org/C118716","wikidata":"https://www.wikidata.org/wiki/Q5514725","display_name":"GTP'","level":3,"score":0.49819469451904297},{"id":"https://openalex.org/C2779817904","wikidata":"https://www.wikidata.org/wiki/Q422582","display_name":"Guanosine diphosphate","level":5,"score":0.49452635645866394},{"id":"https://openalex.org/C80631254","wikidata":"https://www.wikidata.org/wiki/Q407438","display_name":"G protein","level":3,"score":0.42715099453926086},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2650800943374634},{"id":"https://openalex.org/C2776638253","wikidata":"https://www.wikidata.org/wiki/Q392227","display_name":"Guanosine triphosphate","level":4,"score":0.23608046770095825},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.21175932884216309},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.1640494167804718},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001905","descriptor_name":"Botulinum Toxins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002970","descriptor_name":"Cleavage Stage, Ovum","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002970","descriptor_name":"Cleavage Stage, Ovum","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D008841","descriptor_name":"Actin Cytoskeleton","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D008845","descriptor_name":"Microinjections","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011499","descriptor_name":"Protein Processing, Post-Translational","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014982","descriptor_name":"Xenopus laevis","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D019204","descriptor_name":"GTP-Binding Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D019204","descriptor_name":"GTP-Binding Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020692","descriptor_name":"rab3 GTP-Binding Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020730","descriptor_name":"Guanine Nucleotide Dissociation Inhibitors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020742","descriptor_name":"rhoA GTP-Binding Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036002","descriptor_name":"ADP Ribose Transferases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D062947","descriptor_name":"rho-Specific Guanine Nucleotide Dissociation Inhibitors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1083/jcb.120.5.1187","doi":"https://doi.org/10.1083/jcb.120.5.1187","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.120.5.1187","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2119720","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2119720/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2119720/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cell Biol","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:915903","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2119720","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:8436590","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8436590","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.274.1408","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.274.1408","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/52/1d/J_Cell_Biol_1993_Mar_1_120(5)_1187-1195.tar.gz","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.321.7406","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.321.7406","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jcb.rupress.org/content/120/5/1187.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2119720","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2119720/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2119720/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cell Biol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"},{"id":"https://openalex.org/F4320338089","display_name":"National Institute for Physiological Sciences","ror":"https://ror.org/048v13307"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2018307646.pdf","grobid_xml":"https://content.openalex.org/works/W2018307646.grobid-xml"},"referenced_works_count":68,"referenced_works":["https://openalex.org/W19904141","https://openalex.org/W69400297","https://openalex.org/W129191972","https://openalex.org/W154051135","https://openalex.org/W967874190","https://openalex.org/W1507228972","https://openalex.org/W1513592846","https://openalex.org/W1513979636","https://openalex.org/W1514066364","https://openalex.org/W1533587302","https://openalex.org/W1543554885","https://openalex.org/W1544627945","https://openalex.org/W1556438409","https://openalex.org/W1558257735","https://openalex.org/W1558802435","https://openalex.org/W1568345151","https://openalex.org/W1575806712","https://openalex.org/W1577261854","https://openalex.org/W1584977435","https://openalex.org/W1602846778","https://openalex.org/W1607046039","https://openalex.org/W1624592313","https://openalex.org/W1656440259","https://openalex.org/W1671027038","https://openalex.org/W1766782882","https://openalex.org/W1805425496","https://openalex.org/W1876989035","https://openalex.org/W1948317796","https://openalex.org/W1954540662","https://openalex.org/W1964912103","https://openalex.org/W1980865411","https://openalex.org/W1989173844","https://openalex.org/W1994139415","https://openalex.org/W1999929858","https://openalex.org/W2001330472","https://openalex.org/W2007660746","https://openalex.org/W2010238435","https://openalex.org/W2014987538","https://openalex.org/W2016507624","https://openalex.org/W2023294596","https://openalex.org/W2028020136","https://openalex.org/W2029872541","https://openalex.org/W2038314921","https://openalex.org/W2039117682","https://openalex.org/W2042004604","https://openalex.org/W2047177788","https://openalex.org/W2047705047","https://openalex.org/W2048784760","https://openalex.org/W2066139399","https://openalex.org/W2068446924","https://openalex.org/W2069873229","https://openalex.org/W2074155719","https://openalex.org/W2084699108","https://openalex.org/W2089887078","https://openalex.org/W2093226717","https://openalex.org/W2093454379","https://openalex.org/W2095581687","https://openalex.org/W2097751889","https://openalex.org/W2107332774","https://openalex.org/W2111188818","https://openalex.org/W2120425861","https://openalex.org/W2122413961","https://openalex.org/W2135977869","https://openalex.org/W2144634347","https://openalex.org/W2167151786","https://openalex.org/W2302025612","https://openalex.org/W2804275696","https://openalex.org/W4297820747"],"related_works":["https://openalex.org/W1602846778","https://openalex.org/W1805425496","https://openalex.org/W1998682793","https://openalex.org/W1656440259","https://openalex.org/W219103137","https://openalex.org/W2323332533","https://openalex.org/W1989173844","https://openalex.org/W2072887494","https://openalex.org/W2045193600","https://openalex.org/W2313642356"],"abstract_inverted_index":{"Evidence":[0],"is":[1,33],"accumulating":[2],"that":[3,221],"the":[4,10,27,50,87,106,113,125,146,153,161,171,180,185,197,200,230,234],"rho":[5,53,61,79,126,134,168,181,216,222],"family,":[6,127],"a":[7,210],"member":[8,123],"of":[9,42,52,97,108,119,124,133,157,167,176,189,199,214],"ras":[11],"p21-related":[12],"small":[13],"GTP-binding":[14],"protein":[15],"superfamily,":[16],"regulates":[17,229],"cell":[18,20],"morphology,":[19],"motility,":[21],"and":[22,71,81],"smooth":[23],"muscle":[24],"contraction":[25],"through":[26,233],"actomyosin":[28,31,158,235],"system.":[29,236],"The":[30,93],"system":[32],"also":[34],"known":[35,75],"to":[36,76,82],"be":[37],"essential":[38],"for":[39],"cytoplasmic":[40,88,95,187,231],"division":[41,89,96,142,188,232],"cells":[43],"(cytokinesis).":[44],"In":[45],"this":[46],"study,":[47],"we":[48],"examined":[49],"action":[51],"p21,":[54,121],"its":[55,63,84,226],"inhibitory":[56],"GDP/GTP":[57,65],"exchange":[58,66],"protein,":[59,67],"named":[60,68],"GDI,":[62],"stimulatory":[64],"smg":[69,110],"GDS,":[70],"botulinum":[72],"ADP-ribosyltransferase":[73],"C3,":[74],"selectively":[77],"ADP-ribosylate":[78],"p21":[80,178,202,223],"impair":[83],"function,":[85],"in":[86],"using":[90],"Xenopus":[91,98,190],"embryos.":[92],"sperm-induced":[94,186],"embryos":[99,107,191,198],"was":[100,150,164,192],"not":[101],"affected":[102],"by":[103,131,152,194,204],"microinjection":[104,132,195],"into":[105,196],"either":[109],"GDS":[111],"or":[112,136],"guanosine-5'-(3-O-thio)triphosphate":[114],"(GTP":[115],"gamma":[116,173],"S)-bound":[117],"form":[118,175],"rhoA":[120,177,201],"one":[122],"but":[128,145],"completely":[129],"inhibited":[130,193],"GDI":[135,169,182],"C3.":[137],"Under":[138],"these":[139],"conditions,":[140],"nuclear":[141],"occurred":[143],"normally":[144],"furrow":[147],"formation,":[148],"which":[149,206],"induced":[151],"contractile":[154],"ring":[155],"consisting":[156],"just":[159],"beneath":[160],"plasma":[162],"membrane,":[163],"impaired.":[165],"Comicroinjection":[166],"with":[170,225],"GTP":[172],"S-bound":[174],"prevented":[179],"action.":[183],"Moreover,":[184],"pre-ADP-ribosylated":[203],"C3":[205],"might":[207],"serve":[208],"as":[209],"dominant":[211],"negative":[212],"inhibitor":[213],"endogenous":[215],"p21.":[217],"These":[218],"results":[219],"indicate":[220],"together":[224],"regulatory":[227],"proteins":[228]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}