{"id":"https://openalex.org/W2018279599","doi":"https://doi.org/10.1128/aac.46.2.371-377.2002","title":"Susceptibilities to Telithromycin and Six Other Agents and Prevalence of Macrolide Resistance Due to L4 Ribosomal Protein Mutation among 992 Pneumococci from 10 Central and Eastern European Countries","display_name":"Susceptibilities to Telithromycin and Six Other Agents and Prevalence of Macrolide Resistance Due to L4 Ribosomal Protein Mutation among 992 Pneumococci from 10 Central and Eastern European Countries","publication_year":2002,"publication_date":"2002-02-01","ids":{"openalex":"https://openalex.org/W2018279599","doi":"https://doi.org/10.1128/aac.46.2.371-377.2002","mag":"2018279599","pmid":"https://pubmed.ncbi.nlm.nih.gov/11796344","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/127073"},"language":"en","primary_location":{"id":"doi:10.1128/aac.46.2.371-377.2002","doi":"https://doi.org/10.1128/aac.46.2.371-377.2002","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aac.46.2.371-377.2002","pdf_url":null,"source":{"id":"https://openalex.org/S47215897","display_name":"Antimicrobial Agents and Chemotherapy","issn_l":"0066-4804","issn":["0066-4804","1070-6283","1098-6596"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial Agents and Chemotherapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC127073","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112129767","display_name":"Kensuke Nagai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kensuke Nagai","raw_affiliation_strings":["Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania","Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania 17033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania","institution_ids":["https://openalex.org/I82783531"]},{"raw_affiliation_string":"Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania 17033, USA","institution_ids":["https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007565957","display_name":"Peter C. Appelbaum","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Peter C. Appelbaum","raw_affiliation_strings":["Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania","institution_ids":["https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070030726","display_name":"Todd A. Davies","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Todd A. Davies","raw_affiliation_strings":["Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania","institution_ids":["https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020895943","display_name":"Linda M. Kelly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Linda M. Kelly","raw_affiliation_strings":["Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania","institution_ids":["https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047701314","display_name":"Dianne B. Hoellman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dianne B. Hoellman","raw_affiliation_strings":["Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania","institution_ids":["https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023343752","display_name":"Arjana Tambi\u0107 Andra\u0161evi\u0107","orcid":"https://orcid.org/0000-0001-6232-1465","observed_orcids":["https://orcid.org/0000-0001-6232-1465"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arjana Tambic Andrasevic","raw_affiliation_strings":["University Hospital of Infectious Diseases, Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital of Infectious Diseases, Zagreb, Croatia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012614961","display_name":"Liga Drukalska","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115958","display_name":"Children's Clinical University Hospital","ror":"https://ror.org/01js8h045","country_code":"LV","type":"healthcare","lineage":["https://openalex.org/I4210115958"]}],"countries":["LV"],"is_corresponding":false,"raw_author_name":"Liga Drukalska","raw_affiliation_strings":["Children's Hospital of Medical Academy of Latvia, Riga, Latvia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Hospital of Medical Academy of Latvia, Riga, Latvia","institution_ids":["https://openalex.org/I4210115958"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049516465","display_name":"Waleria Hryniewicz","orcid":"https://orcid.org/0000-0002-3651-9790","observed_orcids":["https://orcid.org/0000-0002-3651-9790"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Waleria Hryniewicz","raw_affiliation_strings":["SeraVaccine Laboratory, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SeraVaccine Laboratory, Warsaw, Poland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069770283","display_name":"Michael R. Jacobs","orcid":"https://orcid.org/0000-0002-4235-7855","observed_orcids":["https://orcid.org/0000-0002-4235-7855","https://orcid.org/0000-0002-2979-5551"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael R. Jacobs","raw_affiliation_strings":["Case Western Reserve University, Cleveland, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Case Western Reserve University, Cleveland, Ohio","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043068750","display_name":"Jana Kolman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I153976015","display_name":"University of Ljubljana","ror":"https://ror.org/05njb9z20","country_code":"SI","type":"education","lineage":["https://openalex.org/I153976015"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Jana Kolman","raw_affiliation_strings":["University of Ljubljana, Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Ljubljana, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I153976015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065398808","display_name":"Jolanta Miciulevi\u010dien\u0117","orcid":"https://orcid.org/0000-0002-5111-4775","observed_orcids":["https://orcid.org/0000-0002-5111-4775"]},"institutions":[{"id":"https://openalex.org/I2802445891","display_name":"Hospital of Lithuanian University of Health Sciences Kaunas Clinics","ror":"https://ror.org/058hsp657","country_code":"LT","type":"healthcare","lineage":["https://openalex.org/I131736796","https://openalex.org/I2802445891"]}],"countries":["LT"],"is_corresponding":false,"raw_author_name":"Jolanta Miciuleviciene","raw_affiliation_strings":["Kaunas Medical University Hospital, Kaunas, Lithuania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kaunas Medical University Hospital, Kaunas, Lithuania","institution_ids":["https://openalex.org/I2802445891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039230933","display_name":"Marina Pan\u0103","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110620","display_name":"Institutul Cantacuzino","ror":"https://ror.org/02qbhr955","country_code":"RO","type":"facility","lineage":["https://openalex.org/I4210110620"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Marina Pana","raw_affiliation_strings":["Institute Cantacuzino, Bucharest, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute Cantacuzino, Bucharest, Romania","institution_ids":["https://openalex.org/I4210110620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071084315","display_name":"Lena Setchanova","orcid":"https://orcid.org/0009-0001-5573-1236","observed_orcids":["https://orcid.org/0009-0001-5573-1236"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lena Setchanova","raw_affiliation_strings":["Hospital of Infectious Diseases, Medical Academy, Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital of Infectious Diseases, Medical Academy, Sofia, Bulgaria","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087455828","display_name":"Marianne Konkoly Thege","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151547","display_name":"National Center for Epidemiology","ror":"https://ror.org/05drnnd98","country_code":"HU","type":"facility","lineage":["https://openalex.org/I4210151547"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Marianne Konkoly Thege","raw_affiliation_strings":["National Center for Epidemiology, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Center for Epidemiology, Budapest, Hungary","institution_ids":["https://openalex.org/I4210151547"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082743584","display_name":"Helena Hupkov\u00e1","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Helena Hupkova","raw_affiliation_strings":["St. CyrilMethod Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St. CyrilMethod Hospital","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074519680","display_name":"Jan Trupl","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jan Trupl","raw_affiliation_strings":["National Cancer Institute, Bratislava Slovak Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Cancer Institute, Bratislava Slovak Republic","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043910528","display_name":"Pavla Urb\u00e1\u0161kov\u00e1","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pavla Urbaskova","raw_affiliation_strings":["National Antibiotic Reference Laboratory, Prague, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Antibiotic Reference Laboratory, Prague, Czech Republic","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":6,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5007565957"],"corresponding_institution_ids":["https://openalex.org/I82783531"],"apc_list":null,"apc_paid":null,"fwci":11.6741,"has_fulltext":false,"cited_by_count":83,"citation_normalized_percentile":{"value":0.99137388,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"46","issue":"2","first_page":"371","last_page":"377"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10654","display_name":"Pneumonia and Respiratory Infections","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10654","display_name":"Pneumonia and Respiratory Infections","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.0340999998152256,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/streptococcus-pneumoniae","display_name":"Streptococcus pneumoniae","score":0.984000027179718},{"id":"https://openalex.org/keywords/telithromycin","display_name":"telithromycin","score":0.9470000267028809},{"id":"https://openalex.org/keywords/levofloxacin-resistance","display_name":"levofloxacin resistance","score":0.8169999718666077},{"id":"https://openalex.org/keywords/erythromycin-resistance","display_name":"erythromycin resistance","score":0.847000002861023},{"id":"https://openalex.org/keywords/penicillin-resistance","display_name":"penicillin resistance","score":0.828000009059906},{"id":"https://openalex.org/keywords/ermb","display_name":"ermB","score":0.6449999809265137},{"id":"https://openalex.org/keywords/clonal-relatedness","display_name":"clonal relatedness","score":0.7710000276565552},{"id":"https://openalex.org/keywords/antimicrobial-susceptibility","display_name":"antimicrobial susceptibility","score":0.7929999828338623},{"id":"https://openalex.org/keywords/central-and-eastern-europe","display_name":"Central and Eastern Europe","score":0.7760000228881836},{"id":"https://openalex.org/keywords/respiratory-tract-infections","display_name":"respiratory infections","score":0.9430000185966492},{"id":"https://openalex.org/keywords/fluoroquinolone-resistance","display_name":"fluoroquinolone resistance","score":0.7319999933242798}],"concepts":[{"id":"https://openalex.org/C2780810561","wikidata":"https://www.wikidata.org/wiki/Q2736135","display_name":"Telithromycin","level":4,"score":0.9698276519775391},{"id":"https://openalex.org/C2780894585","wikidata":"https://www.wikidata.org/wiki/Q1445686","display_name":"Ketolide","level":4,"score":0.6808071136474609},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5665926337242126},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.532714307308197},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.4776562452316284},{"id":"https://openalex.org/C67905577","wikidata":"https://www.wikidata.org/wiki/Q215980","display_name":"Ribosomal RNA","level":3,"score":0.4528915286064148},{"id":"https://openalex.org/C38062823","wikidata":"https://www.wikidata.org/wiki/Q3408228","display_name":"Ribosomal protein","level":5,"score":0.4209115207195282},{"id":"https://openalex.org/C2781253189","wikidata":"https://www.wikidata.org/wiki/Q221179","display_name":"Streptococcus pneumoniae","level":3,"score":0.4131922423839569},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40058013796806335},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.355949342250824},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.2761659622192383},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.26649463176727295},{"id":"https://openalex.org/C88478588","wikidata":"https://www.wikidata.org/wiki/Q42244","display_name":"Ribosome","level":4,"score":0.12508949637413025},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10937058925628662},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000890","descriptor_name":"Anti-Infective Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D005060","descriptor_name":"Europe","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012269","descriptor_name":"Ribosomal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012269","descriptor_name":"Ribosomal Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012703","descriptor_name":"Serotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013296","descriptor_name":"Streptococcus pneumoniae","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013296","descriptor_name":"Streptococcus pneumoniae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013296","descriptor_name":"Streptococcus pneumoniae","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D015242","descriptor_name":"Ofloxacin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018942","descriptor_name":"Macrolides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D024881","descriptor_name":"Drug Resistance, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D048628","descriptor_name":"Ketolides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064704","descriptor_name":"Levofloxacin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1128/aac.46.2.371-377.2002","doi":"https://doi.org/10.1128/aac.46.2.371-377.2002","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aac.46.2.371-377.2002","pdf_url":null,"source":{"id":"https://openalex.org/S47215897","display_name":"Antimicrobial Agents and Chemotherapy","issn_l":"0066-4804","issn":["0066-4804","1070-6283","1098-6596"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial Agents and Chemotherapy","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:108063","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC127073","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:11796344","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11796344","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial agents and chemotherapy","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:127073","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC127073/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrob Agents Chemother","raw_type":"Text"},{"id":"pmh:oai:lsmu.lt:20.500.12512/70093","doi":null,"is_oa":false,"landing_page_url":"http://www.ncbi.nlm.nih.gov/pubmed/11796344","pdf_url":null,"source":{"id":"https://openalex.org/S7407055191","display_name":"Lithuanian University of Health Sciences","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:108063","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC127073","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W611976593","https://openalex.org/W1581962345","https://openalex.org/W1955612312","https://openalex.org/W1978701966","https://openalex.org/W1988907123","https://openalex.org/W1992130833","https://openalex.org/W2035816966","https://openalex.org/W2051039256","https://openalex.org/W2090128232","https://openalex.org/W2099610826","https://openalex.org/W2100797845","https://openalex.org/W2109170829","https://openalex.org/W2119252133","https://openalex.org/W2120736676","https://openalex.org/W2127686385","https://openalex.org/W2135493947","https://openalex.org/W2136359775","https://openalex.org/W2137596770","https://openalex.org/W2141697188","https://openalex.org/W2143919088","https://openalex.org/W2144857212","https://openalex.org/W2154967711","https://openalex.org/W2155021683","https://openalex.org/W2155152002","https://openalex.org/W2156363940","https://openalex.org/W2159101163","https://openalex.org/W2161309291","https://openalex.org/W2163423447","https://openalex.org/W2163771433","https://openalex.org/W2165928362","https://openalex.org/W2171728511","https://openalex.org/W2336287850","https://openalex.org/W2900095673","https://openalex.org/W3027545634"],"related_works":["https://openalex.org/W2112840124","https://openalex.org/W2134777170","https://openalex.org/W2157523168","https://openalex.org/W1972911755","https://openalex.org/W1995336729","https://openalex.org/W2066012137","https://openalex.org/W2093733084","https://openalex.org/W7096074776","https://openalex.org/W2165904641","https://openalex.org/W2014546133"],"abstract_inverted_index":{"The":[0,30,55],"macrolide":[1],"and":[2,17,26,40,52,65,72,81,90,99,103,109,166,189,225],"levofloxacin":[3,200],"susceptibilities":[4],"of":[5,8,32,60,68,77,86,95,105,126,220,232],"992":[6],"isolates":[7,49,61,121,223],"Streptococcus":[9,47],"pneumoniae":[10,48,120,129,138,222,240],"from":[11,184,207],"clinical":[12],"specimens":[13],"collected":[14],"in":[15,21,24,117,132],"1999":[16],"2000":[18],"were":[19,50,70,79,88,97,107,147,191,205],"determined":[20],"10":[22],"centers":[23],"Central":[25],"Eastern":[27],"European":[28],"countries.":[29],"prevalences":[31],"penicillin":[33],"G-intermediate":[34],"(MICs,":[35,42,201],"0.125":[36,89],"to":[37,149,199],"1":[38],"microg/ml)":[39,46,203],"penicillin-resistant":[41],"<":[43,212],"or":[44,213],"=2":[45],"14.3":[51],"16.6%,":[53],"respectively.":[54,112],"MICs":[56],"at":[57,211],"which":[58],"50%":[59],"are":[62],"inhibited":[63],"(MIC(50)s)":[64],"the":[66,123,185,230],"MIC(90)s":[67],"telithromycin":[69],"0.016":[71],"0.06":[73,80,108],"microg/ml,":[74,83,92,101,111],"respectively;":[75,84,93,102],"those":[76,85,94,104],"erythromycin":[78],">64":[82,91,100,110],"azithromycin":[87],"clarithromycin":[96],"0.03":[98],"clindamycin":[106],"Erythromycin":[113],"resistance":[114],"was":[115,130,216],"found":[116,148],"180":[118],"S.":[119,128,137,221,239],"(18.1%);":[122],"highest":[124],"prevalence":[125],"erythromycin-resistant":[127,136],"observed":[131],"Hungary":[133],"(35.5%).":[134],"Among":[135],"isolates,":[139],"strains":[140,145,153,158,164,170,180,196],"harboring":[141],"erm(B)":[142],"genes":[143,156,168],"(125":[144],"[69.4%])":[146],"be":[150,227],"predominant":[151],"over":[152],"with":[154],"mef(E)":[155],"(25":[157],"[13.4%]),":[159],"L4":[160,182],"protein":[161],"mutations":[162,183],"(28":[163],"[15.6%]),":[165],"erm(A)":[167],"(2":[169],"[1.1%]).":[171],"Similar":[172],"pulsed-field":[173],"gel":[174],"electrophoresis":[175],"patterns":[176],"suggested":[177],"that":[178],"some":[179],"containing":[181],"Slovak":[186],"Republic,":[187],"Bulgaria,":[188],"Latvia":[190],"clonally":[192],"related.":[193],"Of":[194],"nine":[195],"highly":[197],"resistant":[198],">8":[202],"six":[204],"isolated":[206],"Zagreb,":[208],"Croatia.":[209],"Telithromycin":[210],"=0.5":[214],"microg/ml":[215],"active":[217],"against":[218],"99.8%":[219],"tested":[224],"may":[226],"useful":[228],"for":[229],"treatment":[231],"respiratory":[233],"tract":[234],"infections":[235],"caused":[236],"by":[237],"macrolide-resistant":[238],"isolates.":[241]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
