{"id":"https://openalex.org/W2018269704","doi":"https://doi.org/10.1016/j.jchromb.2007.12.019","title":"Dissociation of neopterin and 7,8-dihydroneopterin from plasma components before HPLC analysis","display_name":"Dissociation of neopterin and 7,8-dihydroneopterin from plasma components before HPLC analysis","publication_year":2008,"publication_date":"2008-01-07","ids":{"openalex":"https://openalex.org/W2018269704","doi":"https://doi.org/10.1016/j.jchromb.2007.12.019","mag":"2018269704","pmid":"https://pubmed.ncbi.nlm.nih.gov/18234568"},"language":"en","primary_location":{"id":"doi:10.1016/j.jchromb.2007.12.019","doi":"https://doi.org/10.1016/j.jchromb.2007.12.019","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jchromb.2007.12.019","pdf_url":null,"source":{"id":"https://openalex.org/S103248676","display_name":"Journal of Chromatography B","issn_l":"1570-0232","issn":["1570-0232","1873-376X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chromatography B","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074519681","display_name":"Elizabeth A. Flavall","orcid":"https://orcid.org/0000-0002-7775-2214","observed_orcids":["https://orcid.org/0000-0002-7775-2214"]},"institutions":[{"id":"https://openalex.org/I185492890","display_name":"University of Canterbury","ror":"https://ror.org/03y7q9t39","country_code":"NZ","type":"education","lineage":["https://openalex.org/I185492890"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Elizabeth A. Flavall","raw_affiliation_strings":["Free Radical Biochemistry Laboratory, University of Canterbury, Christchurch, New Zealand","Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Christchurch, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Free Radical Biochemistry Laboratory, University of Canterbury, Christchurch, New Zealand","institution_ids":["https://openalex.org/I185492890"]},{"raw_affiliation_string":"Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Christchurch, New Zealand","institution_ids":["https://openalex.org/I185492890"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043113042","display_name":"Elizabeth M. Crone","orcid":"https://orcid.org/0000-0002-2705-7459","observed_orcids":["https://orcid.org/0000-0002-2705-7459"]},"institutions":[{"id":"https://openalex.org/I185492890","display_name":"University of Canterbury","ror":"https://ror.org/03y7q9t39","country_code":"NZ","type":"education","lineage":["https://openalex.org/I185492890"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Elizabeth M. Crone","raw_affiliation_strings":["Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Christchurch, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Christchurch, New Zealand","institution_ids":["https://openalex.org/I185492890"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112063899","display_name":"Grant A. Moore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802773633","display_name":"Christchurch Hospital","ror":"https://ror.org/003nvpm64","country_code":"NZ","type":"healthcare","lineage":["https://openalex.org/I2802773633","https://openalex.org/I4405259026"]},{"id":"https://openalex.org/I4210097713","display_name":"Canterbury Health Laboratories","ror":"https://ror.org/00wspbn44","country_code":"NZ","type":"facility","lineage":["https://openalex.org/I4210097713"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Grant A. Moore","raw_affiliation_strings":["Toxicology Laboratory, Canterbury Health Labs, Christchurch Hospital, Christchurch, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Toxicology Laboratory, Canterbury Health Labs, Christchurch Hospital, Christchurch, New Zealand","institution_ids":["https://openalex.org/I2802773633","https://openalex.org/I4210097713"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060625745","display_name":"Steven P. Gieseg","orcid":"https://orcid.org/0000-0002-3862-1385","observed_orcids":["https://orcid.org/0000-0002-3862-1385"]},"institutions":[{"id":"https://openalex.org/I185492890","display_name":"University of Canterbury","ror":"https://ror.org/03y7q9t39","country_code":"NZ","type":"education","lineage":["https://openalex.org/I185492890"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Steven P. Gieseg","raw_affiliation_strings":["Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Christchurch, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Christchurch, New Zealand","institution_ids":["https://openalex.org/I185492890"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5060625745"],"corresponding_institution_ids":["https://openalex.org/I185492890"],"apc_list":{"value":3640,"currency":"USD","value_usd":3640},"apc_paid":null,"fwci":10.5934,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.97581374,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"863","issue":"1","first_page":"167","last_page":"171"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.23600000143051147,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.23600000143051147,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.17900000512599945,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14245","display_name":"Biomarkers in Disease Mechanisms","score":0.14980000257492065,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neopterin","display_name":"neopterin","score":1.0},{"id":"https://openalex.org/keywords/7-8-dihydroneopterin","display_name":"7,8-dihydroneopterin","score":1.0},{"id":"https://openalex.org/keywords/pterins","display_name":"pterins","score":0.6990000009536743},{"id":"https://openalex.org/keywords/plasma-protein-precipitation","display_name":"plasma protein precipitation","score":0.6449999809265137},{"id":"https://openalex.org/keywords/sample-preparation","display_name":"sample preparation","score":0.6359999775886536},{"id":"https://openalex.org/keywords/acetonitrile-precipitation","display_name":"acetonitrile precipitation","score":0.7549999952316284},{"id":"https://openalex.org/keywords/trichloroacetic-acid-precipitation","display_name":"trichloroacetic acid precipitation","score":0.9359999895095825},{"id":"https://openalex.org/keywords/sample-oxidation","display_name":"sample oxidation","score":0.5260000228881836},{"id":"https://openalex.org/keywords/septicemia","display_name":"septicemia","score":0.7749999761581421},{"id":"https://openalex.org/keywords/hplc-with-fluorescence-detection","display_name":"HPLC-fluorescence detection","score":0.7170000076293945}],"concepts":[{"id":"https://openalex.org/C2776603314","wikidata":"https://www.wikidata.org/wiki/Q908292","display_name":"Neopterin","level":2,"score":0.9900927543640137},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8895318508148193},{"id":"https://openalex.org/C2776055822","wikidata":"https://www.wikidata.org/wiki/Q386702","display_name":"Pterin","level":4,"score":0.7873599529266357},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.70652174949646},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.6834516525268555},{"id":"https://openalex.org/C2777332483","wikidata":"https://www.wikidata.org/wiki/Q410116","display_name":"Trichloroacetic acid","level":2,"score":0.6475938558578491},{"id":"https://openalex.org/C102931765","wikidata":"https://www.wikidata.org/wiki/Q189673","display_name":"Dissociation (chemistry)","level":2,"score":0.5492116212844849},{"id":"https://openalex.org/C2777463227","wikidata":"https://www.wikidata.org/wiki/Q408047","display_name":"Acetonitrile","level":2,"score":0.5362329483032227},{"id":"https://openalex.org/C74774607","wikidata":"https://www.wikidata.org/wiki/Q7251495","display_name":"Protein precipitation","level":3,"score":0.4271330237388611},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2639479637145996},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14021632075309753},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.11232954263687134},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0832643210887909},{"id":"https://openalex.org/C197957613","wikidata":"https://www.wikidata.org/wiki/Q407280","display_name":"Cofactor","level":3,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001798","descriptor_name":"Blood Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007202","descriptor_name":"Indicators and Reagents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014466","descriptor_name":"Ultraviolet Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019798","descriptor_name":"Neopterin","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D019798","descriptor_name":"Neopterin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D019798","descriptor_name":"Neopterin","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jchromb.2007.12.019","doi":"https://doi.org/10.1016/j.jchromb.2007.12.019","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jchromb.2007.12.019","pdf_url":null,"source":{"id":"https://openalex.org/S103248676","display_name":"Journal of Chromatography B","issn_l":"1570-0232","issn":["1570-0232","1873-376X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chromatography B","raw_type":"journal-article"},{"id":"pmid:18234568","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18234568","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chromatography. B, Analytical technologies in the biomedical and life sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320780","display_name":"National Heart Foundation of New Zealand","ror":"https://ror.org/02xwkbq98"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W1500124620","https://openalex.org/W1880607371","https://openalex.org/W1914637123","https://openalex.org/W1936366238","https://openalex.org/W1965049464","https://openalex.org/W1975747683","https://openalex.org/W1976817556","https://openalex.org/W1978204556","https://openalex.org/W1980259022","https://openalex.org/W1982581996","https://openalex.org/W1985581754","https://openalex.org/W1991652411","https://openalex.org/W1994838137","https://openalex.org/W2028038490","https://openalex.org/W2029581635","https://openalex.org/W2030773219","https://openalex.org/W2046900391","https://openalex.org/W2076477264","https://openalex.org/W2090160235","https://openalex.org/W2091319309","https://openalex.org/W2129211817","https://openalex.org/W2133847008","https://openalex.org/W2165233139"],"related_works":["https://openalex.org/W7196968563","https://openalex.org/W7095574744","https://openalex.org/W2073408716","https://openalex.org/W2137919276","https://openalex.org/W1988186340","https://openalex.org/W2076090130","https://openalex.org/W7135499635","https://openalex.org/W7135693784","https://openalex.org/W2045164102","https://openalex.org/W2332337894"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}