{"id":"https://openalex.org/W2018097922","doi":"https://doi.org/10.1016/j.jbiotec.2008.07.1052","title":"Discovery of compound 18 as a novel melanogenesis inhibitor using protein chip-based HTS assay","display_name":"Discovery of compound 18 as a novel melanogenesis inhibitor using protein chip-based HTS assay","publication_year":2008,"publication_date":"2008-10-01","ids":{"openalex":"https://openalex.org/W2018097922","doi":"https://doi.org/10.1016/j.jbiotec.2008.07.1052","mag":"2018097922"},"language":"en","primary_location":{"id":"doi:10.1016/j.jbiotec.2008.07.1052","doi":"https://doi.org/10.1016/j.jbiotec.2008.07.1052","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jbiotec.2008.07.1052","pdf_url":null,"source":{"id":"https://openalex.org/S182099265","display_name":"Journal of Biotechnology","issn_l":"0168-1656","issn":["0168-1656","1873-4863"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biotechnology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089160663","display_name":"Hae Jong Kim","orcid":"https://orcid.org/0000-0002-2735-4154","observed_orcids":["https://orcid.org/0000-0002-2735-4154"]},"institutions":[{"id":"https://openalex.org/I191879574","display_name":"Inha University","ror":"https://ror.org/01easw929","country_code":"KR","type":"education","lineage":["https://openalex.org/I191879574"]},{"id":"https://openalex.org/I4210153373","display_name":"Inha University Hospital","ror":"https://ror.org/04gj5px28","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I191879574","https://openalex.org/I4210153373"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Hae Jong Kim","raw_affiliation_strings":["Department of Biological Engineering, Inha University, Incheon, Republic of Korea","Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","Department of Biological Engineering Inha University  Incheon Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Engineering, Inha University, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I4210153373"]},{"raw_affiliation_string":"Department of Biological Engineering Inha University  Incheon Republic of Korea","institution_ids":["https://openalex.org/I191879574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103404504","display_name":"Chi-Ho Choi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I191879574","display_name":"Inha University","ror":"https://ror.org/01easw929","country_code":"KR","type":"education","lineage":["https://openalex.org/I191879574"]},{"id":"https://openalex.org/I4210153373","display_name":"Inha University Hospital","ror":"https://ror.org/04gj5px28","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I191879574","https://openalex.org/I4210153373"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Chi-Ho Choi","raw_affiliation_strings":["Department of Biological Engineering, Inha University, Incheon, Republic of Korea","Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","Department of Biological Engineering Inha University  Incheon Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Engineering, Inha University, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I4210153373"]},{"raw_affiliation_string":"Department of Biological Engineering Inha University  Incheon Republic of Korea","institution_ids":["https://openalex.org/I191879574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059651113","display_name":"Sung Won Choi","orcid":"https://orcid.org/0000-0002-6321-3834","observed_orcids":["https://orcid.org/0000-0002-6321-3834"]},"institutions":[{"id":"https://openalex.org/I191879574","display_name":"Inha University","ror":"https://ror.org/01easw929","country_code":"KR","type":"education","lineage":["https://openalex.org/I191879574"]},{"id":"https://openalex.org/I4210153373","display_name":"Inha University Hospital","ror":"https://ror.org/04gj5px28","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I191879574","https://openalex.org/I4210153373"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sung Won Choi","raw_affiliation_strings":["Department of Biological Engineering, Inha University, Incheon, Republic of Korea","Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","Department of Biological Engineering Inha University  Incheon Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Engineering, Inha University, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I4210153373"]},{"raw_affiliation_string":"Department of Biological Engineering Inha University  Incheon Republic of Korea","institution_ids":["https://openalex.org/I191879574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100349764","display_name":"Jung-Hyun Kim","orcid":"https://orcid.org/0000-0002-0866-398X","observed_orcids":["https://orcid.org/0000-0002-0866-398X"]},"institutions":[{"id":"https://openalex.org/I191879574","display_name":"Inha University","ror":"https://ror.org/01easw929","country_code":"KR","type":"education","lineage":["https://openalex.org/I191879574"]},{"id":"https://openalex.org/I4210153373","display_name":"Inha University Hospital","ror":"https://ror.org/04gj5px28","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I191879574","https://openalex.org/I4210153373"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jung-Hyun Kim","raw_affiliation_strings":["Department of Biological Engineering, Inha University, Incheon, Republic of Korea","Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","Department of Biological Engineering Inha University  Incheon Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Engineering, Inha University, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I4210153373"]},{"raw_affiliation_string":"Department of Biological Engineering Inha University  Incheon Republic of Korea","institution_ids":["https://openalex.org/I191879574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046343114","display_name":"Jae-Dong Shin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I191879574","display_name":"Inha University","ror":"https://ror.org/01easw929","country_code":"KR","type":"education","lineage":["https://openalex.org/I191879574"]},{"id":"https://openalex.org/I4210153373","display_name":"Inha University Hospital","ror":"https://ror.org/04gj5px28","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I191879574","https://openalex.org/I4210153373"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jae-Dong Shin","raw_affiliation_strings":["Department of Biological Engineering, Inha University, Incheon, Republic of Korea","Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","Department of Biological Engineering Inha University  Incheon Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Engineering, Inha University, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I4210153373"]},{"raw_affiliation_string":"Department of Biological Engineering Inha University  Incheon Republic of Korea","institution_ids":["https://openalex.org/I191879574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110400143","display_name":"Hyang-Bok Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I191879574","display_name":"Inha University","ror":"https://ror.org/01easw929","country_code":"KR","type":"education","lineage":["https://openalex.org/I191879574"]},{"id":"https://openalex.org/I4210153373","display_name":"Inha University Hospital","ror":"https://ror.org/04gj5px28","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I191879574","https://openalex.org/I4210153373"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hyang-Bok Lee","raw_affiliation_strings":["Department of Biological Engineering, Inha University, Incheon, Republic of Korea","Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","Department of Biological Engineering Inha University  Incheon Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Engineering, Inha University, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I4210153373"]},{"raw_affiliation_string":"Department of Biological Engineering Inha University  Incheon Republic of Korea","institution_ids":["https://openalex.org/I191879574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054225543","display_name":"Jeonghyun Shin","orcid":"https://orcid.org/0000-0002-4995-9533","observed_orcids":["https://orcid.org/0000-0002-4995-9533"]},"institutions":[{"id":"https://openalex.org/I191879574","display_name":"Inha University","ror":"https://ror.org/01easw929","country_code":"KR","type":"education","lineage":["https://openalex.org/I191879574"]},{"id":"https://openalex.org/I4210153373","display_name":"Inha University Hospital","ror":"https://ror.org/04gj5px28","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I191879574","https://openalex.org/I4210153373"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jeong-Hyun Shin","raw_affiliation_strings":["Department of Biological Engineering, Inha University, Incheon, Republic of Korea","Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","Department of Biological Engineering Inha University  Incheon Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Engineering, Inha University, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I4210153373"]},{"raw_affiliation_string":"Department of Biological Engineering Inha University  Incheon Republic of Korea","institution_ids":["https://openalex.org/I191879574"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059379025","display_name":"Eun-Ki Kim","orcid":"https://orcid.org/0000-0001-9100-9905","observed_orcids":["https://orcid.org/0000-0001-9100-9905"]},"institutions":[{"id":"https://openalex.org/I191879574","display_name":"Inha University","ror":"https://ror.org/01easw929","country_code":"KR","type":"education","lineage":["https://openalex.org/I191879574"]},{"id":"https://openalex.org/I4210153373","display_name":"Inha University Hospital","ror":"https://ror.org/04gj5px28","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I191879574","https://openalex.org/I4210153373"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Eun-Ki Kim","raw_affiliation_strings":["Department of Biological Engineering, Inha University, Incheon, Republic of Korea","Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","Department of Biological Engineering Inha University  Incheon Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Engineering, Inha University, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I191879574"]},{"raw_affiliation_string":"Department of Dermatology, Inha Hospital, Incheon, Republic of Korea","institution_ids":["https://openalex.org/I4210153373"]},{"raw_affiliation_string":"Department of Biological Engineering Inha University  Incheon Republic of Korea","institution_ids":["https://openalex.org/I191879574"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5089160663"],"corresponding_institution_ids":["https://openalex.org/I191879574","https://openalex.org/I4210153373"],"apc_list":{"value":4360,"currency":"USD","value_usd":4360},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.12781073,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"136","issue":null,"first_page":"S453","last_page":"S453"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11144","display_name":"melanin and skin pigmentation","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11144","display_name":"melanin and skin pigmentation","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11533","display_name":"Melanoma and MAPK Pathways","score":0.0071000000461936,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12257","display_name":"Bioactive natural compounds","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/melanogenesis-inhibitors","display_name":"melanogenesis inhibitors","score":0.9190000295639038},{"id":"https://openalex.org/keywords/melanin-synthesis","display_name":"melanogenesis","score":0.703000009059906},{"id":"https://openalex.org/keywords/high-throughput-screening","display_name":"high-throughput screening","score":0.734000027179718}],"concepts":[{"id":"https://openalex.org/C2994587664","wikidata":"https://www.wikidata.org/wiki/Q494918","display_name":"Protein chip","level":2,"score":0.559637188911438},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5392758846282959},{"id":"https://openalex.org/C165005293","wikidata":"https://www.wikidata.org/wiki/Q1074500","display_name":"Chip","level":2,"score":0.5152633190155029},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.36891600489616394},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1709039807319641},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1620042324066162},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.08463993668556213},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jbiotec.2008.07.1052","doi":"https://doi.org/10.1016/j.jbiotec.2008.07.1052","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jbiotec.2008.07.1052","pdf_url":null,"source":{"id":"https://openalex.org/S182099265","display_name":"Journal of Biotechnology","issn_l":"0168-1656","issn":["0168-1656","1873-4863"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biotechnology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.46810001134872437}],"sustainable_development_goals_aurora":[{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.4399999976158142}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W2020410981","https://openalex.org/W2024103019","https://openalex.org/W2048947200","https://openalex.org/W2124214914"],"related_works":["https://openalex.org/W2948807893","https://openalex.org/W2899084033","https://openalex.org/W2778153218","https://openalex.org/W2748952813","https://openalex.org/W1531601525","https://openalex.org/W4233212111","https://openalex.org/W2478196496","https://openalex.org/W4300922226","https://openalex.org/W2763493846","https://openalex.org/W2324843897"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-21T07:43:02.447757","created_date":"2025-10-10T00:00:00"}
