{"id":"https://openalex.org/W2017872978","doi":"https://doi.org/10.7326/0003-4819-159-10-201311190-00007","title":"Statins and Cognitive Function","display_name":"Statins and Cognitive Function","publication_year":2013,"publication_date":"2013-11-19","ids":{"openalex":"https://openalex.org/W2017872978","doi":"https://doi.org/10.7326/0003-4819-159-10-201311190-00007","mag":"2017872978","pmid":"https://pubmed.ncbi.nlm.nih.gov/24247674"},"language":"en","primary_location":{"id":"doi:10.7326/0003-4819-159-10-201311190-00007","doi":"https://doi.org/10.7326/0003-4819-159-10-201311190-00007","is_oa":false,"landing_page_url":"https://doi.org/10.7326/0003-4819-159-10-201311190-00007","pdf_url":null,"source":{"id":"https://openalex.org/S119722071","display_name":"Annals of Internal Medicine","issn_l":"0003-4819","issn":["0003-4819","1539-3704"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316812","host_organization_name":"American College of Physicians","host_organization_lineage":["https://openalex.org/P4310316812"],"host_organization_lineage_names":["American College of Physicians"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Internal Medicine","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032056956","display_name":"Karl M. Richardson","orcid":"https://orcid.org/0000-0003-0665-4294","observed_orcids":["https://orcid.org/0000-0003-0665-4294"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4210143392","display_name":"University of Pennsylvania Health System","ror":"https://ror.org/04h81rw26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210143392"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karl Richardson","raw_affiliation_strings":["From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4210143392","https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021257656","display_name":"Marisa A. Schoen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4210143392","display_name":"University of Pennsylvania Health System","ror":"https://ror.org/04h81rw26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210143392"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marisa Schoen","raw_affiliation_strings":["From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4210143392","https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053189023","display_name":"Benjamin C. French","orcid":"https://orcid.org/0000-0001-9265-5378","observed_orcids":["https://orcid.org/0000-0001-9265-5378"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4210143392","display_name":"University of Pennsylvania Health System","ror":"https://ror.org/04h81rw26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210143392"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin French","raw_affiliation_strings":["From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4210143392","https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069300680","display_name":"Craig A. Umscheid","orcid":"https://orcid.org/0000-0003-1853-1013","observed_orcids":["https://orcid.org/0000-0003-1853-1013"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4210143392","display_name":"University of Pennsylvania Health System","ror":"https://ror.org/04h81rw26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210143392"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Craig A. Umscheid","raw_affiliation_strings":["From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4210143392","https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055999863","display_name":"Matthew D. Mitchell","orcid":"https://orcid.org/0000-0003-3065-1608","observed_orcids":["https://orcid.org/0000-0003-3065-1608"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4210143392","display_name":"University of Pennsylvania Health System","ror":"https://ror.org/04h81rw26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210143392"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew D. Mitchell","raw_affiliation_strings":["From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4210143392","https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088881304","display_name":"Steven Edward Arnold","orcid":"https://orcid.org/0000-0002-9487-415X","observed_orcids":["https://orcid.org/0000-0002-9487-415X"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4210143392","display_name":"University of Pennsylvania Health System","ror":"https://ror.org/04h81rw26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210143392"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven E. Arnold","raw_affiliation_strings":["From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4210143392","https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029257839","display_name":"Paul A. Heidenreich","orcid":"https://orcid.org/0000-0001-7730-8490","observed_orcids":["https://orcid.org/0000-0001-7730-8490"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4210143392","display_name":"University of Pennsylvania Health System","ror":"https://ror.org/04h81rw26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210143392"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul A. Heidenreich","raw_affiliation_strings":["From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4210143392","https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067149045","display_name":"Daniel James Rader","orcid":"https://orcid.org/0000-0002-9245-9876","observed_orcids":["https://orcid.org/0000-0002-9245-9876"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4210143392","display_name":"University of Pennsylvania Health System","ror":"https://ror.org/04h81rw26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210143392"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel J. Rader","raw_affiliation_strings":["From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4210143392","https://openalex.org/I79576946"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090234654","display_name":"Emil M. deGoma","orcid":"https://orcid.org/0000-0001-9439-6912","observed_orcids":["https://orcid.org/0000-0001-9439-6912"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4210143392","display_name":"University of Pennsylvania Health System","ror":"https://ror.org/04h81rw26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210143392"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emil M. deGoma","raw_affiliation_strings":["From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Perelman School of Medicine, University of Pennsylvania, and University of Pennsylvania Health System, Philadelphia, Pennsylvania, and Stanford University Medical Center, Stanford, California","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4210143392","https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.6289,"has_fulltext":false,"cited_by_count":258,"citation_normalized_percentile":{"value":0.98059701,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"159","issue":"10","first_page":"688","last_page":"697"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.5673999786376953,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.5673999786376953,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.39579999446868896,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13077","display_name":"Cancer-related cognitive impairment studies","score":0.013299999758601189,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":1.0},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.9869999885559082},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.8109999895095825},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9399999976158142},{"id":"https://openalex.org/keywords/dementia","display_name":"dementia","score":0.9950000047683716},{"id":"https://openalex.org/keywords/mild-cognitive-impairment","display_name":"mild cognitive impairment","score":1.0},{"id":"https://openalex.org/keywords/executive-function","display_name":"executive function","score":0.6899999976158142},{"id":"https://openalex.org/keywords/memory","display_name":"memory","score":0.8050000071525574},{"id":"https://openalex.org/keywords/processing-speed","display_name":"processing speed","score":0.8090000152587891},{"id":"https://openalex.org/keywords/post-marketing-surveillance","display_name":"post-marketing surveillance","score":0.7160000205039978},{"id":"https://openalex.org/keywords/adverse-drug-reactions","display_name":"adverse drug reactions","score":0.8009999990463257},{"id":"https://openalex.org/keywords/high-intensity-statin-therapy","display_name":"high-intensity statin therapy","score":0.8629999756813049}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8592040538787842},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.7560080289840698},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.6693086624145508},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5304780602455139},{"id":"https://openalex.org/C2984863031","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Cognitive decline","level":4,"score":0.5197250843048096},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.5146547555923462},{"id":"https://openalex.org/C2776478404","wikidata":"https://www.wikidata.org/wiki/Q1105187","display_name":"Cochrane Library","level":3,"score":0.5099760293960571},{"id":"https://openalex.org/C2777466982","wikidata":"https://www.wikidata.org/wiki/Q5227287","display_name":"Data extraction","level":3,"score":0.4909105896949768},{"id":"https://openalex.org/C6057870","wikidata":"https://www.wikidata.org/wiki/Q5141248","display_name":"Cognitive test","level":3,"score":0.4456242620944977},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.4237115979194641},{"id":"https://openalex.org/C185711340","wikidata":"https://www.wikidata.org/wiki/Q5347381","display_name":"Effects of sleep deprivation on cognitive performance","level":3,"score":0.4174352288246155},{"id":"https://openalex.org/C105641010","wikidata":"https://www.wikidata.org/wiki/Q7920941","display_name":"Verbal memory","level":3,"score":0.41609278321266174},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.32327139377593994},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.28855109214782715},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.2282361388206482},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22294029593467712},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D003704","descriptor_name":"Dementia","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008569","descriptor_name":"Memory Disorders","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014486","descriptor_name":"United States Food and Drug Administration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016907","descriptor_name":"Adverse Drug Reaction Reporting Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019161","descriptor_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D019161","descriptor_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.7326/0003-4819-159-10-201311190-00007","doi":"https://doi.org/10.7326/0003-4819-159-10-201311190-00007","is_oa":false,"landing_page_url":"https://doi.org/10.7326/0003-4819-159-10-201311190-00007","pdf_url":null,"source":{"id":"https://openalex.org/S119722071","display_name":"Annals of Internal Medicine","issn_l":"0003-4819","issn":["0003-4819","1539-3704"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316812","host_organization_name":"American College of Physicians","host_organization_lineage":["https://openalex.org/P4310316812"],"host_organization_lineage_names":["American College of Physicians"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Internal Medicine","raw_type":"journal-article"},{"id":"pmid:24247674","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24247674","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of internal medicine","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.688.3045","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.688.3045","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://annals.org/data/Journals/AIM/928838/0000605-201311190-00007.pdf","raw_type":"text"},{"id":"mag:3026031128","doi":null,"is_oa":false,"landing_page_url":"https://www.acpjournals.org/doi/full/10.7326/0003-4819-159-10-201311190-00007","pdf_url":null,"source":{"id":"https://openalex.org/S119722071","display_name":"Annals of Internal Medicine","issn_l":"0003-4819","issn":["0003-4819","1539-3704"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316812","host_organization_name":"American College of Physicians","host_organization_lineage":["https://openalex.org/P4310316812"],"host_organization_lineage_names":["American College of Physicians"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Annals of Internal Medicine","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":84,"referenced_works":["https://openalex.org/W764148","https://openalex.org/W204490223","https://openalex.org/W424467158","https://openalex.org/W1061550300","https://openalex.org/W1497505709","https://openalex.org/W1502120889","https://openalex.org/W1513881453","https://openalex.org/W1589121689","https://openalex.org/W1972868237","https://openalex.org/W1976326436","https://openalex.org/W1981680557","https://openalex.org/W1982349077","https://openalex.org/W1982793603","https://openalex.org/W1986968958","https://openalex.org/W1987646963","https://openalex.org/W1989454237","https://openalex.org/W1995583689","https://openalex.org/W1996607203","https://openalex.org/W1998664054","https://openalex.org/W2006166262","https://openalex.org/W2010033213","https://openalex.org/W2014263073","https://openalex.org/W2017230805","https://openalex.org/W2024536861","https://openalex.org/W2025916746","https://openalex.org/W2028360010","https://openalex.org/W2030025114","https://openalex.org/W2030223490","https://openalex.org/W2031459011","https://openalex.org/W2040365078","https://openalex.org/W2041304593","https://openalex.org/W2041559439","https://openalex.org/W2043582228","https://openalex.org/W2045905042","https://openalex.org/W2046718416","https://openalex.org/W2047026973","https://openalex.org/W2047553180","https://openalex.org/W2047613132","https://openalex.org/W2049462104","https://openalex.org/W2062987239","https://openalex.org/W2068358701","https://openalex.org/W2068448803","https://openalex.org/W2068959237","https://openalex.org/W2070126411","https://openalex.org/W2076965707","https://openalex.org/W2082506593","https://openalex.org/W2090132603","https://openalex.org/W2093043874","https://openalex.org/W2094766256","https://openalex.org/W2098034696","https://openalex.org/W2098878950","https://openalex.org/W2098923148","https://openalex.org/W2099556509","https://openalex.org/W2104197073","https://openalex.org/W2104352791","https://openalex.org/W2104675861","https://openalex.org/W2104999604","https://openalex.org/W2105390649","https://openalex.org/W2105632027","https://openalex.org/W2107328434","https://openalex.org/W2107341600","https://openalex.org/W2108326377","https://openalex.org/W2123457140","https://openalex.org/W2134236426","https://openalex.org/W2135234221","https://openalex.org/W2135631433","https://openalex.org/W2135812251","https://openalex.org/W2138733401","https://openalex.org/W2139168999","https://openalex.org/W2141362400","https://openalex.org/W2142847995","https://openalex.org/W2143813789","https://openalex.org/W2144063780","https://openalex.org/W2145123193","https://openalex.org/W2147048440","https://openalex.org/W2147782235","https://openalex.org/W2157724767","https://openalex.org/W2160093157","https://openalex.org/W2161990655","https://openalex.org/W2165010366","https://openalex.org/W2167082719","https://openalex.org/W2247997571","https://openalex.org/W2320375755","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2506784016","https://openalex.org/W7096780344","https://openalex.org/W2021222203","https://openalex.org/W2066832227","https://openalex.org/W2071869403","https://openalex.org/W4375817381","https://openalex.org/W7097602842","https://openalex.org/W2137309530","https://openalex.org/W3095913137","https://openalex.org/W2317536016"],"abstract_inverted_index":{"BACKGROUND:":[0],"Despite":[1],"the":[2,13,24,149,169,207,223,242],"U.S.":[3],"Food":[4],"and":[5,17,34,56,59,81,101,201,213],"Drug":[6],"Administration":[7],"(FDA)":[8],"warning":[9],"regarding":[10],"cognitive":[11,105,125,131,136],"impairment,":[12],"relationship":[14],"between":[15],"statins":[16,27,164,226,238],"cognition":[18,63],"remains":[19],"unknown.":[20],"PURPOSE:":[21],"To":[22],"examine":[23],"effect":[25,224,236],"of":[26,79,98,121,148,181,192,203,209,225,237,244],"on":[28,227,239],"cognition.":[29,228],"DATA":[30,68,87],"SOURCES:":[31],"PubMed,":[32],"Embase,":[33],"Cochrane":[35],"Library":[36],"from":[37,44],"inception":[38],"through":[39,47],"October":[40],"2012;":[41],"FDA":[42,150],"databases":[43,153],"January":[45],"1986":[46],"March":[48],"2012.":[49],"STUDY":[50],"SELECTION:":[51],"Randomized,":[52],"controlled":[53],"trials":[54],"(RCTs)":[55],"cohort,":[57],"case-control,":[58],"cross-sectional":[60],"studies":[61,215],"evaluating":[62],"in":[64,104,130,189],"patients":[65],"receiving":[66],"statins.":[67,254],"EXTRACTION:":[69],"Two":[70],"reviewers":[71],"extracted":[72],"data,":[73],"1":[74,82],"reviewer":[75,83],"assessed":[76],"study":[77],"risk":[78,202],"bias,":[80],"checked":[84],"all":[85],"assessments.":[86],"SYNTHESIS:":[88],"Among":[89],"statin":[90],"users,":[91],"low-quality":[92],"evidence":[93,116,193,246],"suggested":[94,117],"no":[95,102,118],"increased":[96,119],"incidence":[97,120],"Alzheimer":[99],"disease":[100],"difference":[103],"performance":[106,132,137],"related":[107,133],"to":[108,134,168,218,252],"procedural":[109],"memory,":[110,142],"attention,":[111],"or":[112,123,127,145,197],"motor":[113],"speed.":[114],"Moderate-quality":[115],"dementia":[122],"mild":[124],"impairment":[126],"any":[128],"change":[129],"global":[135],"scores,":[138],"executive":[139],"function,":[140],"declarative":[141],"processing":[143],"speed,":[144],"visuoperception.":[146],"Examination":[147],"postmarketing":[151],"surveillance":[152],"revealed":[154],"a":[155],"low":[156,196],"reporting":[157],"rate":[158],"for":[159,185],"cognitive-related":[160],"adverse":[161,235],"events":[162],"with":[163,172,250],"that":[165,194],"was":[166],"similar":[167],"rates":[170],"seen":[171],"other":[173],"commonly":[174],"prescribed":[175],"cardiovascular":[176],"medications.":[177],"LIMITATIONS:":[178],"The":[179],"absence":[180],"many":[182],"well-powered":[183],"RCTs":[184],"most":[186],"outcomes":[187],"resulted":[188],"final":[190],"strengths":[191],"were":[195],"moderate.":[198],"Imprecision,":[199],"inconsistency,":[200],"bias":[204],"also":[205],"limited":[206],"strength":[208,243],"findings.":[210],"CONCLUSION:":[211],"Larger":[212],"better-designed":[214],"are":[216],"needed":[217],"draw":[219],"unequivocal":[220],"conclusions":[221],"about":[222],"Published":[229],"data":[230],"do":[231],"not":[232],"suggest":[233],"an":[234],"cognition;":[240],"however,":[241],"available":[245],"is":[247],"limited,":[248],"particularly":[249],"regard":[251],"high-dose":[253]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":18},{"year":2019,"cited_by_count":24},{"year":2018,"cited_by_count":25},{"year":2017,"cited_by_count":20},{"year":2016,"cited_by_count":41},{"year":2015,"cited_by_count":34},{"year":2014,"cited_by_count":29},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}