{"id":"https://openalex.org/W2017767113","doi":"https://doi.org/10.1016/j.bpj.2011.05.029","title":"Quantification of Collagen Organization in the Peripheral Human Cornea at Micron-Scale Resolution","display_name":"Quantification of Collagen Organization in the Peripheral Human Cornea at Micron-Scale Resolution","publication_year":2011,"publication_date":"2011-07-01","ids":{"openalex":"https://openalex.org/W2017767113","doi":"https://doi.org/10.1016/j.bpj.2011.05.029","mag":"2017767113","pmid":"https://pubmed.ncbi.nlm.nih.gov/21723812","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3127175"},"language":"en","primary_location":{"id":"doi:10.1016/j.bpj.2011.05.029","doi":"https://doi.org/10.1016/j.bpj.2011.05.029","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2011.05.029","pdf_url":"http://www.cell.com/article/S0006349511005996/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0006349511005996/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018662655","display_name":"Craig Boote","orcid":"https://orcid.org/0000-0003-0348-6547","observed_orcids":["https://orcid.org/0000-0003-0348-6547"]},"institutions":[{"id":"https://openalex.org/I79510175","display_name":"Cardiff University","ror":"https://ror.org/03kk7td41","country_code":"GB","type":"education","lineage":["https://openalex.org/I79510175"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Craig Boote","raw_affiliation_strings":["Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom","institution_ids":["https://openalex.org/I79510175"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070554583","display_name":"Christina S. Kamma\u2010Lorger","orcid":"https://orcid.org/0000-0001-6686-9161","observed_orcids":["https://orcid.org/0000-0001-6686-9161"]},"institutions":[{"id":"https://openalex.org/I79510175","display_name":"Cardiff University","ror":"https://ror.org/03kk7td41","country_code":"GB","type":"education","lineage":["https://openalex.org/I79510175"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christina\u00a0S. Kamma-Lorger","raw_affiliation_strings":["Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom","institution_ids":["https://openalex.org/I79510175"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068820925","display_name":"Sally Hayes","orcid":"https://orcid.org/0000-0001-8550-0108","observed_orcids":["https://orcid.org/0000-0001-8550-0108"]},"institutions":[{"id":"https://openalex.org/I79510175","display_name":"Cardiff University","ror":"https://ror.org/03kk7td41","country_code":"GB","type":"education","lineage":["https://openalex.org/I79510175"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sally Hayes","raw_affiliation_strings":["Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom","institution_ids":["https://openalex.org/I79510175"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059275624","display_name":"Jonathan L. Harris","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79510175","display_name":"Cardiff University","ror":"https://ror.org/03kk7td41","country_code":"GB","type":"education","lineage":["https://openalex.org/I79510175"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jonathan Harris","raw_affiliation_strings":["Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom","institution_ids":["https://openalex.org/I79510175"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044552579","display_name":"Manfred C. Burghammer","orcid":"https://orcid.org/0000-0002-2262-3431","observed_orcids":["https://orcid.org/0000-0002-2262-3431"]},"institutions":[{"id":"https://openalex.org/I2801997478","display_name":"European Synchrotron Radiation Facility","ror":"https://ror.org/02550n020","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801997478"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Manfred Burghammer","raw_affiliation_strings":["European Synchrotron Radiation Facility, Grenoble, France","European Synchrotron Radiation Facility,#N#Grenoble, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Synchrotron Radiation Facility, Grenoble, France","institution_ids":["https://openalex.org/I2801997478"]},{"raw_affiliation_string":"European Synchrotron Radiation Facility,#N#Grenoble, France","institution_ids":["https://openalex.org/I2801997478"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113578148","display_name":"Jennifer C. Hiller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802711169","display_name":"Diamond Light Source","ror":"https://ror.org/05etxs293","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2802711169"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jennifer Hiller","raw_affiliation_strings":["Diamond Light Source, Didcot, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diamond Light Source, Didcot, United Kingdom","institution_ids":["https://openalex.org/I2802711169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087855376","display_name":"Nicholas J. Terrill","orcid":"https://orcid.org/0000-0002-8783-1282","observed_orcids":["https://orcid.org/0000-0002-8783-1282"]},"institutions":[{"id":"https://openalex.org/I2802711169","display_name":"Diamond Light Source","ror":"https://ror.org/05etxs293","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2802711169"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nicholas\u00a0J. Terrill","raw_affiliation_strings":["Diamond Light Source, Didcot, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diamond Light Source, Didcot, United Kingdom","institution_ids":["https://openalex.org/I2802711169"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046052577","display_name":"Keith M. Meek","orcid":"https://orcid.org/0000-0002-9948-7538","observed_orcids":["https://orcid.org/0000-0002-9948-7538"]},"institutions":[{"id":"https://openalex.org/I79510175","display_name":"Cardiff University","ror":"https://ror.org/03kk7td41","country_code":"GB","type":"education","lineage":["https://openalex.org/I79510175"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Keith\u00a0M. Meek","raw_affiliation_strings":["Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom","institution_ids":["https://openalex.org/I79510175"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5046052577"],"corresponding_institution_ids":["https://openalex.org/I79510175"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":3.7946,"has_fulltext":true,"cited_by_count":78,"citation_normalized_percentile":{"value":0.92222716,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":92,"max":99},"biblio":{"volume":"101","issue":"1","first_page":"33","last_page":"42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11828","display_name":"Corneal Surgery and Treatments","score":0.012500000186264515,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12085","display_name":"Collagen: Extraction and Characterization","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/limbus","display_name":"limbus","score":0.8579999804496765},{"id":"https://openalex.org/keywords/collagen-fibril-orientation","display_name":"collagen fibril orientation","score":0.949999988079071},{"id":"https://openalex.org/keywords/collagen-fibril-diameter","display_name":"collagen fibril diameter","score":0.9520000219345093},{"id":"https://openalex.org/keywords/scleral-collagen","display_name":"scleral collagen","score":0.8519999980926514},{"id":"https://openalex.org/keywords/corneal-biomechanics","display_name":"corneal biomechanics","score":0.9269999861717224},{"id":"https://openalex.org/keywords/corneal-curvature","display_name":"corneal curvature","score":0.7570000290870667},{"id":"https://openalex.org/keywords/peripheral-cornea","display_name":"peripheral cornea","score":0.6480000019073486}],"concepts":[{"id":"https://openalex.org/C2776882836","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Cornea","level":2,"score":0.9218542575836182},{"id":"https://openalex.org/C3019161014","wikidata":"https://www.wikidata.org/wiki/Q26868","display_name":"Collagen fibril","level":2,"score":0.8549314737319946},{"id":"https://openalex.org/C27523624","wikidata":"https://www.wikidata.org/wiki/Q14860849","display_name":"Fibril","level":2,"score":0.8226419687271118},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5628336071968079},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.4580795168876648},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.39397940039634705},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.345367431640625},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.33709079027175903},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32294726371765137},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1168457567691803},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11268147826194763},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09912773966789246}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D003315","descriptor_name":"Cornea","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014961","descriptor_name":"X-Ray Diffraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016850","descriptor_name":"Limbus Corneae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D024022","descriptor_name":"Fibrillar Collagens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.bpj.2011.05.029","doi":"https://doi.org/10.1016/j.bpj.2011.05.029","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2011.05.029","pdf_url":"http://www.cell.com/article/S0006349511005996/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2395756","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3127175","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3127175","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3127175","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophys J","raw_type":"Text"},{"id":"pmid:21723812","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21723812","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical journal","raw_type":"Journal Article"},{"id":"pmh:oai:https://orca.cardiff.ac.uk:22427","doi":null,"is_oa":true,"landing_page_url":"https://orca.cardiff.ac.uk/id/eprint/22427/1/Quantification_of_Collagen_Organization.pdf","pdf_url":"https://orca.cardiff.ac.uk/id/eprint/22427/1/Quantification_of_Collagen_Organization.pdf","source":{"id":"https://openalex.org/S4306401195","display_name":"ORCA Online Research @Cardiff (Cardiff University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79510175","host_organization_name":"Cardiff University","host_organization_lineage":["https://openalex.org/I79510175"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1016/j.bpj.2011.05.029","doi":"https://doi.org/10.1016/j.bpj.2011.05.029","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2011.05.029","pdf_url":"http://www.cell.com/article/S0006349511005996/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2017767113.pdf","grobid_xml":"https://content.openalex.org/works/W2017767113.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W62362543","https://openalex.org/W102722070","https://openalex.org/W175929622","https://openalex.org/W196823532","https://openalex.org/W1521002311","https://openalex.org/W1581587561","https://openalex.org/W1968640085","https://openalex.org/W1969336599","https://openalex.org/W1981848125","https://openalex.org/W1992257884","https://openalex.org/W2010368260","https://openalex.org/W2011392956","https://openalex.org/W2016061051","https://openalex.org/W2017785209","https://openalex.org/W2026110135","https://openalex.org/W2026419440","https://openalex.org/W2029299561","https://openalex.org/W2035794738","https://openalex.org/W2039016753","https://openalex.org/W2048270975","https://openalex.org/W2049222380","https://openalex.org/W2050061802","https://openalex.org/W2069326128","https://openalex.org/W2070582711","https://openalex.org/W2074781029","https://openalex.org/W2081339779","https://openalex.org/W2083803155","https://openalex.org/W2093593517","https://openalex.org/W2095516478","https://openalex.org/W2104515875","https://openalex.org/W2138587025","https://openalex.org/W2140246441","https://openalex.org/W2142742598","https://openalex.org/W2148130034","https://openalex.org/W2148209835","https://openalex.org/W2155177190","https://openalex.org/W2159259628","https://openalex.org/W2407695040","https://openalex.org/W2842556333","https://openalex.org/W2971629176","https://openalex.org/W6607164528"],"related_works":["https://openalex.org/W1981848125","https://openalex.org/W2081339779","https://openalex.org/W102722070","https://openalex.org/W2016061051","https://openalex.org/W2095516478","https://openalex.org/W2061365012","https://openalex.org/W2047053579","https://openalex.org/W2007287018","https://openalex.org/W2048270975","https://openalex.org/W2148209835"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}