{"id":"https://openalex.org/W2017757245","doi":"https://doi.org/10.1007/s00296-008-0750-1","title":"Assessment of adenosine deaminase levels in rheumatoid arthritis patients receiving anti-TNF-\u03b1 therapy","display_name":"Assessment of adenosine deaminase levels in rheumatoid arthritis patients receiving anti-TNF-\u03b1 therapy","publication_year":2008,"publication_date":"2008-10-24","ids":{"openalex":"https://openalex.org/W2017757245","doi":"https://doi.org/10.1007/s00296-008-0750-1","mag":"2017757245","pmid":"https://pubmed.ncbi.nlm.nih.gov/18953538"},"language":"en","primary_location":{"id":"doi:10.1007/s00296-008-0750-1","doi":"https://doi.org/10.1007/s00296-008-0750-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00296-008-0750-1","pdf_url":null,"source":{"id":"https://openalex.org/S50823678","display_name":"Rheumatology International","issn_l":"0172-8172","issn":["0172-8172","1437-160X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatology International","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083583908","display_name":"Burak Erer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110321","display_name":"\u00dcmraniye E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/023wdy559","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4210110321"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Burak Erer","raw_affiliation_strings":["Department of Rheumatology, Umraniye Education and Research Hospital, Istanbul, Turkey. burakerer@yahoo.com","Department of Rheumatology, Umraniye Education and Research Hospital, Istanbul, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, Umraniye Education and Research Hospital, Istanbul, Turkey. burakerer@yahoo.com","institution_ids":["https://openalex.org/I4210110321"]},{"raw_affiliation_string":"Department of Rheumatology, Umraniye Education and Research Hospital, Istanbul, Turkey","institution_ids":["https://openalex.org/I4210110321"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029492275","display_name":"G\u00fcl\u015fen Y\u0131lmaz","orcid":"https://orcid.org/0000-0002-9630-3852","observed_orcids":["https://orcid.org/0000-0002-9630-3852"]},"institutions":[{"id":"https://openalex.org/I4405277310","display_name":"Ankara E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/027wtj018","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I1303077703","https://openalex.org/I4405277310"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Gulsen Yilmaz","raw_affiliation_strings":["Department of Biochemistry, Ankara Education and Research Hospital, Ankara, Turkey","Ankara Education and Research Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Ankara Education and Research Hospital, Ankara, Turkey","institution_ids":["https://openalex.org/I4405277310"]},{"raw_affiliation_string":"Ankara Education and Research Hospital","institution_ids":["https://openalex.org/I4405277310"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101778422","display_name":"Fatma Meri\u00e7 Y\u0131lmaz","orcid":"https://orcid.org/0000-0002-8252-6975","observed_orcids":["https://orcid.org/0000-0002-8252-6975"]},"institutions":[{"id":"https://openalex.org/I4405277310","display_name":"Ankara E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/027wtj018","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I1303077703","https://openalex.org/I4405277310"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Fatma Meric Yilmaz","raw_affiliation_strings":["Department of Biochemistry, Ankara Education and Research Hospital, Ankara, Turkey","Ankara Education and Research Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Ankara Education and Research Hospital, Ankara, Turkey","institution_ids":["https://openalex.org/I4405277310"]},{"raw_affiliation_string":"Ankara Education and Research Hospital","institution_ids":["https://openalex.org/I4405277310"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113462748","display_name":"Seyfettin K\u00f6kl\u00fc","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405277310","display_name":"Ankara E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/027wtj018","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I1303077703","https://openalex.org/I4405277310"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Seyfettin Koklu","raw_affiliation_strings":["Department of Gastroenterohepatology, Ankara Education and Research Hospital, Ankara, Turkey","Ankara Education and Research Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterohepatology, Ankara Education and Research Hospital, Ankara, Turkey","institution_ids":["https://openalex.org/I4405277310"]},{"raw_affiliation_string":"Ankara Education and Research Hospital","institution_ids":["https://openalex.org/I4405277310"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5083583908"],"corresponding_institution_ids":["https://openalex.org/I4210110321"],"apc_list":{"value":4990,"currency":"USD","value_usd":4990},"apc_paid":null,"fwci":2.3011,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.86984505,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"29","issue":"6","first_page":"651","last_page":"654"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adenosine-deaminase","display_name":"adenosine deaminase","score":0.9330000281333923},{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.9940000176429749},{"id":"https://openalex.org/keywords/anti-tnf-therapy","display_name":"anti-TNF therapy","score":0.9890000224113464},{"id":"https://openalex.org/keywords/tuberculosis-reactivation","display_name":"tuberculosis reactivation","score":0.9670000076293945},{"id":"https://openalex.org/keywords/dmard-therapy","display_name":"DMARD therapy","score":0.6729999780654907},{"id":"https://openalex.org/keywords/tuberculin-skin-test","display_name":"tuberculin skin test","score":0.8140000104904175},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.7360000014305115},{"id":"https://openalex.org/keywords/tuberculosis-diagnosis","display_name":"tuberculosis diagnosis","score":0.5659999847412109},{"id":"https://openalex.org/keywords/remission","display_name":"remission","score":0.6430000066757202}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9478505849838257},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.8500462770462036},{"id":"https://openalex.org/C34628245","wikidata":"https://www.wikidata.org/wiki/Q356093","display_name":"Adenosine deaminase","level":3,"score":0.8443377017974854},{"id":"https://openalex.org/C198451711","wikidata":"https://www.wikidata.org/wiki/Q327657","display_name":"Rheumatology","level":2,"score":0.8312630653381348},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6726721525192261},{"id":"https://openalex.org/C2779722408","wikidata":"https://www.wikidata.org/wiki/Q1536078","display_name":"TNF inhibitor","level":4,"score":0.44836729764938354},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.44734877347946167},{"id":"https://openalex.org/C2776991684","wikidata":"https://www.wikidata.org/wiki/Q190012","display_name":"Adenosine","level":2,"score":0.4144808053970337},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.35986602306365967},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.33828485012054443},{"id":"https://openalex.org/C2777226972","wikidata":"https://www.wikidata.org/wiki/Q415343","display_name":"Etanercept","level":3,"score":0.23024162650108337}],"mesh":[{"descriptor_ui":"D000243","descriptor_name":"Adenosine Deaminase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D004334","descriptor_name":"Drug Administration Schedule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018501","descriptor_name":"Antirheumatic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s00296-008-0750-1","doi":"https://doi.org/10.1007/s00296-008-0750-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00296-008-0750-1","pdf_url":null,"source":{"id":"https://openalex.org/S50823678","display_name":"Rheumatology International","issn_l":"0172-8172","issn":["0172-8172","1437-160X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatology International","raw_type":"journal-article"},{"id":"pmid:18953538","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18953538","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatology international","raw_type":"Journal Article"},{"id":"pmh:162a6d24-8ffd-4acc-88c1-aa3573f9db35","doi":null,"is_oa":false,"landing_page_url":"https://avesis.aybu.edu.tr/publication/details/162a6d24-8ffd-4acc-88c1-aa3573f9db35/oai","pdf_url":null,"source":{"id":"https://openalex.org/S7407055213","display_name":"AYBU AVESIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W120808953","https://openalex.org/W303167040","https://openalex.org/W1513969749","https://openalex.org/W1566830427","https://openalex.org/W1896548939","https://openalex.org/W1963932443","https://openalex.org/W1969317441","https://openalex.org/W1971139360","https://openalex.org/W1972638223","https://openalex.org/W1975207663","https://openalex.org/W2038535814","https://openalex.org/W2058050795","https://openalex.org/W2072563380","https://openalex.org/W2073972803","https://openalex.org/W2089456249","https://openalex.org/W2102303460","https://openalex.org/W2107174064","https://openalex.org/W2116393448","https://openalex.org/W2137544420","https://openalex.org/W2152348310","https://openalex.org/W2282742191","https://openalex.org/W2397828273","https://openalex.org/W2415676255","https://openalex.org/W3203490972","https://openalex.org/W4236928373"],"related_works":["https://openalex.org/W7100327130","https://openalex.org/W2909020482","https://openalex.org/W2115407313","https://openalex.org/W2091540174","https://openalex.org/W2002758276","https://openalex.org/W2516202125","https://openalex.org/W2333297943","https://openalex.org/W2122316162","https://openalex.org/W2324023956","https://openalex.org/W2362391410"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}