{"id":"https://openalex.org/W2017754173","doi":"https://doi.org/10.1152/physrev.00035.2013","title":"Regulation of Increased Blood Flow (Hyperemia) to Muscles During Exercise: A Hierarchy of Competing Physiological Needs","display_name":"Regulation of Increased Blood Flow (Hyperemia) to Muscles During Exercise: A Hierarchy of Competing Physiological Needs","publication_year":2015,"publication_date":"2015-04-01","ids":{"openalex":"https://openalex.org/W2017754173","doi":"https://doi.org/10.1152/physrev.00035.2013","mag":"2017754173","pmid":"https://pubmed.ncbi.nlm.nih.gov/25834232","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4551211"},"language":"en","primary_location":{"id":"doi:10.1152/physrev.00035.2013","doi":"https://doi.org/10.1152/physrev.00035.2013","is_oa":false,"landing_page_url":"https://doi.org/10.1152/physrev.00035.2013","pdf_url":null,"source":{"id":"https://openalex.org/S203035050","display_name":"Physiological Reviews","issn_l":"0031-9333","issn":["0031-9333","1522-1210"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiological Reviews","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4551211","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082946065","display_name":"Michael J. Joyner","orcid":"https://orcid.org/0000-0002-7135-7643","observed_orcids":["https://orcid.org/0000-0002-7135-7643"]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]},{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael J. Joyner","raw_affiliation_strings":["Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota; and Department of Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, Iowa","Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota; and Department of Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, Iowa","institution_ids":["https://openalex.org/I126307644","https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054111868","display_name":"Darren P. Casey","orcid":"https://orcid.org/0000-0003-4564-8604","observed_orcids":["https://orcid.org/0000-0003-4564-8604"]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]},{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Darren P. Casey","raw_affiliation_strings":["Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota; and Department of Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, Iowa","Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota; and Department of Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, Iowa","institution_ids":["https://openalex.org/I126307644","https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":10.4841,"has_fulltext":false,"cited_by_count":833,"citation_normalized_percentile":{"value":0.99346405,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"95","issue":"2","first_page":"549","last_page":"601"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11109","display_name":"Thermoregulation and physiological responses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/exercise-hyperemia","display_name":"exercise hyperemia","score":0.9470000267028809},{"id":"https://openalex.org/keywords/skeletal-muscle-blood-flow","display_name":"skeletal muscle blood flow","score":0.8610000014305115},{"id":"https://openalex.org/keywords/exercise-oxygen-uptake","display_name":"exercise oxygen consumption","score":0.734000027179718},{"id":"https://openalex.org/keywords/vasodilation","display_name":"vasodilation","score":0.6320000290870667},{"id":"https://openalex.org/keywords/systemic-hemodynamics","display_name":"systemic hemodynamics","score":0.5099999904632568},{"id":"https://openalex.org/keywords/cardiac-output","display_name":"cardiac output","score":0.949999988079071},{"id":"https://openalex.org/keywords/blood-pressure-regulation","display_name":"blood pressure regulation","score":0.9750000238418579},{"id":"https://openalex.org/keywords/sympathetic-nervous-system","display_name":"sympathetic nervous system","score":0.8190000057220459},{"id":"https://openalex.org/keywords/microcirculation","display_name":"microcirculation","score":0.953000009059906},{"id":"https://openalex.org/keywords/oxygen-extraction","display_name":"oxygen extraction","score":0.6629999876022339},{"id":"https://openalex.org/keywords/training-adaptation","display_name":"training effects","score":0.6039999723434448}],"concepts":[{"id":"https://openalex.org/C2777032099","wikidata":"https://www.wikidata.org/wiki/Q1225425","display_name":"Dilator","level":2,"score":0.7172043919563293},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.6823433041572571},{"id":"https://openalex.org/C12722491","wikidata":"https://www.wikidata.org/wiki/Q1632335","display_name":"Microcirculation","level":2,"score":0.5551862716674805},{"id":"https://openalex.org/C120770815","wikidata":"https://www.wikidata.org/wiki/Q14859627","display_name":"Vasodilation","level":2,"score":0.5321179032325745},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.49942922592163086},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.47720298171043396},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.4296048879623413},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4274998903274536},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4258801341056824},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42186859250068665},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.41440141201019287},{"id":"https://openalex.org/C72859922","wikidata":"https://www.wikidata.org/wiki/Q11068","display_name":"Circulatory system","level":2,"score":0.41046756505966187},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.32157570123672485},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.250293105840683},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001341","descriptor_name":"Autonomic Nervous System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002302","descriptor_name":"Cardiac Output","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006940","descriptor_name":"Hyperemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006940","descriptor_name":"Hyperemia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D009119","descriptor_name":"Muscle Contraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012039","descriptor_name":"Regional Blood Flow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014664","descriptor_name":"Vasodilation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1152/physrev.00035.2013","doi":"https://doi.org/10.1152/physrev.00035.2013","is_oa":false,"landing_page_url":"https://doi.org/10.1152/physrev.00035.2013","pdf_url":null,"source":{"id":"https://openalex.org/S203035050","display_name":"Physiological Reviews","issn_l":"0031-9333","issn":["0031-9333","1522-1210"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiological Reviews","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4551211","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4551211","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiol Rev","raw_type":"Text"},{"id":"pmid:25834232","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25834232","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiological reviews","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4551211","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4551211","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiol Rev","raw_type":"Text"},"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1172015286","display_name":"Exercise Hyperemia in Humans","funder_award_id":"R01HL119337","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1557575500","display_name":"Role of Adenosine in Compensatory Dilation During Hypoxic Exercise","funder_award_id":"F32AR055819","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G1652223223","display_name":null,"funder_award_id":"AR55819","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G2581461579","display_name":null,"funder_award_id":"HL-46493","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3015807127","display_name":"Mayo Clinic Center for Clinical and Translational Science (CCaTS)","funder_award_id":"UL1TR000135","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G998933788","display_name":null,"funder_award_id":"HL\u2010105467","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":532,"referenced_works":["https://openalex.org/W3924815","https://openalex.org/W15072091","https://openalex.org/W29188874","https://openalex.org/W81115698","https://openalex.org/W82986423","https://openalex.org/W89737606","https://openalex.org/W139774506","https://openalex.org/W148675072","https://openalex.org/W154549817","https://openalex.org/W186526824","https://openalex.org/W189678055","https://openalex.org/W193286686","https://openalex.org/W202976685","https://openalex.org/W419967142","https://openalex.org/W561679196","https://openalex.org/W623886000","https://openalex.org/W1235046880","https://openalex.org/W1480756496","https://openalex.org/W1483300994","https://openalex.org/W1487735792","https://openalex.org/W1490179915","https://openalex.org/W1491802876","https://openalex.org/W1498001087","https://openalex.org/W1503289730","https://openalex.org/W1508883052","https://openalex.org/W1519538616","https://openalex.org/W1522411479","https://openalex.org/W1524137539","https://openalex.org/W1529289359","https://openalex.org/W1532021133","https://openalex.org/W1546657218","https://openalex.org/W1552502560","https://openalex.org/W1554025734","https://openalex.org/W1554068304","https://openalex.org/W1556367950","https://openalex.org/W1564846853","https://openalex.org/W1571154140","https://openalex.org/W1577903510","https://openalex.org/W1579183288","https://openalex.org/W1586781757","https://openalex.org/W1601338463","https://openalex.org/W1603440370","https://openalex.org/W1615913434","https://openalex.org/W1653690885","https://openalex.org/W1667010032","https://openalex.org/W1690183463","https://openalex.org/W1734418304","https://openalex.org/W1757366440","https://openalex.org/W1759262282","https://openalex.org/W1772841449","https://openalex.org/W1777742992","https://openalex.org/W1792396505","https://openalex.org/W1797673917","https://openalex.org/W1811003886","https://openalex.org/W1816755143","https://openalex.org/W1820577040","https://openalex.org/W1831902106","https://openalex.org/W1838918796","https://openalex.org/W1839003392","https://openalex.org/W1843190467","https://openalex.org/W1847452149","https://openalex.org/W1863750593","https://openalex.org/W1882122054","https://openalex.org/W1885795608","https://openalex.org/W1893160504","https://openalex.org/W1907106779","https://openalex.org/W1908107085","https://openalex.org/W1908482431","https://openalex.org/W1912989249","https://openalex.org/W1913457686","https://openalex.org/W1913817533","https://openalex.org/W1919174825","https://openalex.org/W1926550845","https://openalex.org/W1929398776","https://openalex.org/W1935937801","https://openalex.org/W1936910750","https://openalex.org/W1940311765","https://openalex.org/W1948492178","https://openalex.org/W1950337740","https://openalex.org/W1954013673","https://openalex.org/W1965238155","https://openalex.org/W1966066034","https://openalex.org/W1966144243","https://openalex.org/W1967525086","https://openalex.org/W1967659379","https://openalex.org/W1968702251","https://openalex.org/W1968977161","https://openalex.org/W1969127237","https://openalex.org/W1969362766","https://openalex.org/W1969851884","https://openalex.org/W1970445061","https://openalex.org/W1971469692","https://openalex.org/W1974349880","https://openalex.org/W1974921435","https://openalex.org/W1976135674","https://openalex.org/W1976412271","https://openalex.org/W1977824667","https://openalex.org/W1978104136","https://openalex.org/W1978495288","https://openalex.org/W1978771893","https://openalex.org/W1978897412","https://openalex.org/W1978939238","https://openalex.org/W1980471807","https://openalex.org/W1984731234","https://openalex.org/W1985705252","https://openalex.org/W1986772524","https://openalex.org/W1986992048","https://openalex.org/W1987270666","https://openalex.org/W1987300899","https://openalex.org/W1987914240","https://openalex.org/W1988769794","https://openalex.org/W1990376116","https://openalex.org/W1992028466","https://openalex.org/W1992941247","https://openalex.org/W1993113186","https://openalex.org/W1994875454","https://openalex.org/W1996173383","https://openalex.org/W1996298369","https://openalex.org/W1998846672","https://openalex.org/W1998954481","https://openalex.org/W2002562478","https://openalex.org/W2003763550","https://openalex.org/W2003854161","https://openalex.org/W2005188365","https://openalex.org/W2005407033","https://openalex.org/W2005882808","https://openalex.org/W2007469578","https://openalex.org/W2009166480","https://openalex.org/W2009991335","https://openalex.org/W2010213296","https://openalex.org/W2010314855","https://openalex.org/W2010917138","https://openalex.org/W2011279121","https://openalex.org/W2011702667","https://openalex.org/W2011951281","https://openalex.org/W2012183901","https://openalex.org/W2012363381","https://openalex.org/W2012492594","https://openalex.org/W2013276993","https://openalex.org/W2013995202","https://openalex.org/W2014494390","https://openalex.org/W2014823294","https://openalex.org/W2015871572","https://openalex.org/W2016706088","https://openalex.org/W2018462265","https://openalex.org/W2019054755","https://openalex.org/W2020169158","https://openalex.org/W2020870125","https://openalex.org/W2021489239","https://openalex.org/W2021724833","https://openalex.org/W2022455914","https://openalex.org/W2024697941","https://openalex.org/W2025095641","https://openalex.org/W2025118912","https://openalex.org/W2027352420","https://openalex.org/W2027803127","https://openalex.org/W2027982200","https://openalex.org/W2028671335","https://openalex.org/W2029632247","https://openalex.org/W2030118966","https://openalex.org/W2030927622","https://openalex.org/W2030958375","https://openalex.org/W2030990357","https://openalex.org/W2031078098","https://openalex.org/W2032102300","https://openalex.org/W2032502790","https://openalex.org/W2032702492","https://openalex.org/W2033240573","https://openalex.org/W2033823049","https://openalex.org/W2034409336","https://openalex.org/W2034670959","https://openalex.org/W2036342954","https://openalex.org/W2036732048","https://openalex.org/W2037173004","https://openalex.org/W2038111537","https://openalex.org/W2038586113","https://openalex.org/W2039175166","https://openalex.org/W2039790545","https://openalex.org/W2039981344","https://openalex.org/W2040829210","https://openalex.org/W2041029969","https://openalex.org/W2041689988","https://openalex.org/W2042332454","https://openalex.org/W2042364657","https://openalex.org/W2043585674","https://openalex.org/W2044514964","https://openalex.org/W2045676198","https://openalex.org/W2046353662","https://openalex.org/W2046658857","https://openalex.org/W2047038879","https://openalex.org/W2047871442","https://openalex.org/W2048755018","https://openalex.org/W2049660297","https://openalex.org/W2049972637","https://openalex.org/W2050310273","https://openalex.org/W2050527295","https://openalex.org/W2050803078","https://openalex.org/W2050882894","https://openalex.org/W2051183165","https://openalex.org/W2051675694","https://openalex.org/W2052956886","https://openalex.org/W2053910458","https://openalex.org/W2053962294","https://openalex.org/W2054585827","https://openalex.org/W2057253006","https://openalex.org/W2057345592","https://openalex.org/W2060145440","https://openalex.org/W2060767389","https://openalex.org/W2061005453","https://openalex.org/W2061302968","https://openalex.org/W2062514607","https://openalex.org/W2063500547","https://openalex.org/W2063590495","https://openalex.org/W2064477832","https://openalex.org/W2064649750","https://openalex.org/W2065019800","https://openalex.org/W2065266625","https://openalex.org/W2066082209","https://openalex.org/W2066384696","https://openalex.org/W2066602748","https://openalex.org/W2066782344","https://openalex.org/W2066949934","https://openalex.org/W2068281056","https://openalex.org/W2069084921","https://openalex.org/W2069529596","https://openalex.org/W2070968795","https://openalex.org/W2071644767","https://openalex.org/W2072684136","https://openalex.org/W2072797308","https://openalex.org/W2074922229","https://openalex.org/W2075229697","https://openalex.org/W2075696600","https://openalex.org/W2075988974","https://openalex.org/W2076062841","https://openalex.org/W2076123854","https://openalex.org/W2076835260","https://openalex.org/W2077541395","https://openalex.org/W2081919631","https://openalex.org/W2082237741","https://openalex.org/W2082466944","https://openalex.org/W2082702597","https://openalex.org/W2083135549","https://openalex.org/W2083248715","https://openalex.org/W2083481797","https://openalex.org/W2084612608","https://openalex.org/W2085034439","https://openalex.org/W2085047694","https://openalex.org/W2087415857","https://openalex.org/W2089106954","https://openalex.org/W2089665132","https://openalex.org/W2090296913","https://openalex.org/W2090479720","https://openalex.org/W2092928881","https://openalex.org/W2093985390","https://openalex.org/W2094196896","https://openalex.org/W2094290794","https://openalex.org/W2094420579","https://openalex.org/W2095180580","https://openalex.org/W2095430450","https://openalex.org/W2095511577","https://openalex.org/W2095583565","https://openalex.org/W2096464716","https://openalex.org/W2096696113","https://openalex.org/W2097544979","https://openalex.org/W2097653510","https://openalex.org/W2097813267","https://openalex.org/W2097814902","https://openalex.org/W2098850018","https://openalex.org/W2099014154","https://openalex.org/W2099979747","https://openalex.org/W2100164481","https://openalex.org/W2100770709","https://openalex.org/W2100973457","https://openalex.org/W2101019141","https://openalex.org/W2102070560","https://openalex.org/W2102252777","https://openalex.org/W2102703312","https://openalex.org/W2104255482","https://openalex.org/W2104284098","https://openalex.org/W2105449062","https://openalex.org/W2105849343","https://openalex.org/W2106111701","https://openalex.org/W2107621770","https://openalex.org/W2108041082","https://openalex.org/W2108742252","https://openalex.org/W2108900353","https://openalex.org/W2109352669","https://openalex.org/W2109991109","https://openalex.org/W2109997724","https://openalex.org/W2110464164","https://openalex.org/W2111365088","https://openalex.org/W2112073163","https://openalex.org/W2112124443","https://openalex.org/W2112906404","https://openalex.org/W2112912140","https://openalex.org/W2113306155","https://openalex.org/W2113577351","https://openalex.org/W2113667887","https://openalex.org/W2113769239","https://openalex.org/W2114196384","https://openalex.org/W2114380572","https://openalex.org/W2114565603","https://openalex.org/W2114598380","https://openalex.org/W2114857415","https://openalex.org/W2114914136","https://openalex.org/W2115537698","https://openalex.org/W2115785322","https://openalex.org/W2115792507","https://openalex.org/W2116208682","https://openalex.org/W2116374013","https://openalex.org/W2116384729","https://openalex.org/W2116833507","https://openalex.org/W2116895438","https://openalex.org/W2116916090","https://openalex.org/W2116999983","https://openalex.org/W2117082529","https://openalex.org/W2117314868","https://openalex.org/W2118540829","https://openalex.org/W2119632826","https://openalex.org/W2119978369","https://openalex.org/W2120701650","https://openalex.org/W2120728437","https://openalex.org/W2120758308","https://openalex.org/W2121718757","https://openalex.org/W2121924895","https://openalex.org/W2122083613","https://openalex.org/W2124759869","https://openalex.org/W2124773667","https://openalex.org/W2125111318","https://openalex.org/W2125516205","https://openalex.org/W2125646886","https://openalex.org/W2127334473","https://openalex.org/W2127459898","https://openalex.org/W2127801690","https://openalex.org/W2127963725","https://openalex.org/W2127980806","https://openalex.org/W2128075657","https://openalex.org/W2128394280","https://openalex.org/W2128549796","https://openalex.org/W2128724933","https://openalex.org/W2128857489","https://openalex.org/W2129492485","https://openalex.org/W2129539420","https://openalex.org/W2132189265","https://openalex.org/W2132580447","https://openalex.org/W2133081217","https://openalex.org/W2133273378","https://openalex.org/W2133447646","https://openalex.org/W2133617749","https://openalex.org/W2134256354","https://openalex.org/W2135257330","https://openalex.org/W2135270793","https://openalex.org/W2135484120","https://openalex.org/W2135610905","https://openalex.org/W2136386328","https://openalex.org/W2137611335","https://openalex.org/W2138046251","https://openalex.org/W2138555866","https://openalex.org/W2138753146","https://openalex.org/W2139001578","https://openalex.org/W2139250890","https://openalex.org/W2139728486","https://openalex.org/W2139850128","https://openalex.org/W2141106415","https://openalex.org/W2141987212","https://openalex.org/W2142413470","https://openalex.org/W2142459949","https://openalex.org/W2143060519","https://openalex.org/W2144096901","https://openalex.org/W2144107055","https://openalex.org/W2144196030","https://openalex.org/W2144553814","https://openalex.org/W2144693601","https://openalex.org/W2145507715","https://openalex.org/W2145562384","https://openalex.org/W2146345914","https://openalex.org/W2146639117","https://openalex.org/W2146677787","https://openalex.org/W2147701546","https://openalex.org/W2148037483","https://openalex.org/W2148537707","https://openalex.org/W2149061431","https://openalex.org/W2150096529","https://openalex.org/W2150361557","https://openalex.org/W2150425477","https://openalex.org/W2150655878","https://openalex.org/W2152590563","https://openalex.org/W2153409755","https://openalex.org/W2153422377","https://openalex.org/W2154239903","https://openalex.org/W2154935429","https://openalex.org/W2155427587","https://openalex.org/W2155441225","https://openalex.org/W2156916450","https://openalex.org/W2158214634","https://openalex.org/W2158315251","https://openalex.org/W2159218187","https://openalex.org/W2159548391","https://openalex.org/W2160326511","https://openalex.org/W2160883632","https://openalex.org/W2160900475","https://openalex.org/W2162714814","https://openalex.org/W2163420000","https://openalex.org/W2164552936","https://openalex.org/W2164775995","https://openalex.org/W2165012080","https://openalex.org/W2165218367","https://openalex.org/W2165389432","https://openalex.org/W2165872441","https://openalex.org/W2166269531","https://openalex.org/W2166509587","https://openalex.org/W2166977140","https://openalex.org/W2167324549","https://openalex.org/W2167425930","https://openalex.org/W2167498879","https://openalex.org/W2167787808","https://openalex.org/W2168006430","https://openalex.org/W2168767399","https://openalex.org/W2169125742","https://openalex.org/W2169180454","https://openalex.org/W2169182236","https://openalex.org/W2169224412","https://openalex.org/W2169693638","https://openalex.org/W2170710824","https://openalex.org/W2170742224","https://openalex.org/W2171480855","https://openalex.org/W2171791669","https://openalex.org/W2171922350","https://openalex.org/W2171946730","https://openalex.org/W2172118895","https://openalex.org/W2172761340","https://openalex.org/W2173135046","https://openalex.org/W2175966907","https://openalex.org/W2177920344","https://openalex.org/W2178136847","https://openalex.org/W2178990521","https://openalex.org/W2179249193","https://openalex.org/W2179974733","https://openalex.org/W2180738551","https://openalex.org/W2181160159","https://openalex.org/W2181400332","https://openalex.org/W2185500079","https://openalex.org/W2186175012","https://openalex.org/W2188090878","https://openalex.org/W2195603506","https://openalex.org/W2196755532","https://openalex.org/W2200926615","https://openalex.org/W2201559243","https://openalex.org/W2203068796","https://openalex.org/W2207332754","https://openalex.org/W2216029093","https://openalex.org/W2224241353","https://openalex.org/W2226017039","https://openalex.org/W2242960149","https://openalex.org/W2244475019","https://openalex.org/W2254949378","https://openalex.org/W2256366012","https://openalex.org/W2257541983","https://openalex.org/W2259278929","https://openalex.org/W2262501216","https://openalex.org/W2262929329","https://openalex.org/W2266830123","https://openalex.org/W2266956795","https://openalex.org/W2268287919","https://openalex.org/W2268751660","https://openalex.org/W2270224539","https://openalex.org/W2273930673","https://openalex.org/W2274828467","https://openalex.org/W2277288131","https://openalex.org/W2281132864","https://openalex.org/W2284562532","https://openalex.org/W2287396875","https://openalex.org/W2288375262","https://openalex.org/W2289638701","https://openalex.org/W2293946776","https://openalex.org/W2304353233","https://openalex.org/W2311648757","https://openalex.org/W2316941676","https://openalex.org/W2318049542","https://openalex.org/W2323071171","https://openalex.org/W2325659757","https://openalex.org/W2336661543","https://openalex.org/W2336886330","https://openalex.org/W2340972511","https://openalex.org/W2396446279","https://openalex.org/W2397447528","https://openalex.org/W2398692734","https://openalex.org/W2399310305","https://openalex.org/W2400496391","https://openalex.org/W2401134112","https://openalex.org/W2401727061","https://openalex.org/W2402128721","https://openalex.org/W2402292333","https://openalex.org/W2402444000","https://openalex.org/W2405748452","https://openalex.org/W2407496959","https://openalex.org/W2408927066","https://openalex.org/W2409258373","https://openalex.org/W2409339759","https://openalex.org/W2410844219","https://openalex.org/W2411317300","https://openalex.org/W2411353955","https://openalex.org/W2412473902","https://openalex.org/W2412764588","https://openalex.org/W2413093216","https://openalex.org/W2414082932","https://openalex.org/W2414103294","https://openalex.org/W2414574402","https://openalex.org/W2414682545","https://openalex.org/W2415382251","https://openalex.org/W2415480273","https://openalex.org/W2416491380","https://openalex.org/W2418046254","https://openalex.org/W2418117958","https://openalex.org/W2425827454","https://openalex.org/W2429718872","https://openalex.org/W2440723049","https://openalex.org/W2461912031","https://openalex.org/W2474092098","https://openalex.org/W2543642751","https://openalex.org/W2565726191","https://openalex.org/W2972891654","https://openalex.org/W3018034337","https://openalex.org/W3146419461","https://openalex.org/W3209391815","https://openalex.org/W4211047661","https://openalex.org/W4239600486","https://openalex.org/W4250536953","https://openalex.org/W4293117728","https://openalex.org/W4297820770","https://openalex.org/W4388118179","https://openalex.org/W4409075285"],"related_works":["https://openalex.org/W2135395814","https://openalex.org/W1988870583","https://openalex.org/W1885795608","https://openalex.org/W1982769517","https://openalex.org/W2185616362","https://openalex.org/W2095804882","https://openalex.org/W4407791767","https://openalex.org/W3016794490","https://openalex.org/W2325350553","https://openalex.org/W7093352727"],"abstract_inverted_index":{"This":[0],"review":[1,50],"focuses":[2],"on":[3],"how":[4,63],"blood":[5,21,83,114,131,182,189],"flow":[6,22,84,115,183],"to":[7,23,86,130,184,187],"contracting":[8,25,34,100,117,185],"skeletal":[9],"muscles":[10,26,35,101,118,186],"is":[11,19,38,124],"regulated":[12],"during":[13,59,134,191],"exercise":[14,60,87,142,155,195],"in":[15,29,61,89,98,143,196],"humans.":[16,144,197],"The":[17],"idea":[18],"that":[20,74],"the":[24,30,33,51,70,79,90,95,99,109,161,166],"links":[27],"oxygen":[28,54,173],"atmosphere":[31],"with":[32,67],"where":[36],"it":[37],"consumed.":[39],"In":[40],"this":[41,146],"context,":[42],"we":[43],"take":[44],"a":[45,127],"top":[46],"down":[47],"approach":[48],"and":[49,58,69,119,165,175],"basics":[52],"of":[53,171,181],"consumption":[55],"at":[56],"rest":[57],"humans,":[62],"these":[64,104],"values":[65],"change":[66],"training,":[68],"systemic":[71,121,172],"hemodynamic":[72],"adaptations":[73],"support":[75],"them.":[76],"We":[77,92],"highlight":[78],"very":[80,105],"high":[81,106,169],"muscle":[82,137,193],"responses":[85],"discovered":[88],"1980s.":[91],"also":[93],"discuss":[94],"vasodilating":[96],"factors":[97],"responsible":[102],"for":[103,113,154],"flows.":[107],"Finally,":[108],"competition":[110],"between":[111,160],"demand":[112],"by":[116],"maximum":[120],"cardiac":[122],"output":[123],"discussed":[125],"as":[126],"potential":[128],"challenge":[129],"pressure":[132,190],"regulation":[133],"heavy":[135],"large":[136,192],"mass":[138,194],"or":[139],"whole":[140],"body":[141],"At":[145],"time,":[147],"no":[148],"one":[149],"dominant":[150],"dilator":[151],"mechanism":[152],"accounts":[153],"hyperemia.":[156],"Additionally,":[157],"complex":[158],"interactions":[159],"sympathetic":[162,179],"nervous":[163],"system":[164],"microcirculation":[167],"facilitate":[168],"levels":[170],"extraction":[174],"permit":[176],"just":[177],"enough":[178],"control":[180],"regulate":[188]},"counts_by_year":[{"year":2026,"cited_by_count":98},{"year":2025,"cited_by_count":100},{"year":2024,"cited_by_count":93},{"year":2023,"cited_by_count":98},{"year":2022,"cited_by_count":79},{"year":2021,"cited_by_count":88},{"year":2020,"cited_by_count":84},{"year":2019,"cited_by_count":59},{"year":2018,"cited_by_count":50},{"year":2017,"cited_by_count":45},{"year":2016,"cited_by_count":29},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}