{"id":"https://openalex.org/W2017720992","doi":"https://doi.org/10.1007/s11940-013-0226-9","title":"Treatment Options in Newly Diagnosed Glioblastoma","display_name":"Treatment Options in Newly Diagnosed Glioblastoma","publication_year":2013,"publication_date":"2013-04-03","ids":{"openalex":"https://openalex.org/W2017720992","doi":"https://doi.org/10.1007/s11940-013-0226-9","mag":"2017720992","pmid":"https://pubmed.ncbi.nlm.nih.gov/23553038"},"language":"en","primary_location":{"id":"doi:10.1007/s11940-013-0226-9","doi":"https://doi.org/10.1007/s11940-013-0226-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11940-013-0226-9","pdf_url":null,"source":{"id":"https://openalex.org/S73587531","display_name":"Current Treatment Options in Neurology","issn_l":"1092-8480","issn":["1092-8480","1534-3138"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Treatment Options in Neurology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035087247","display_name":"Eudocia Q. Lee","orcid":"https://orcid.org/0000-0003-3355-5179","observed_orcids":["https://orcid.org/0000-0003-3355-5179"]},"institutions":[{"id":"https://openalex.org/I4210102457","display_name":"Center for Neuro-Oncology","ror":"https://ror.org/00z2tp793","country_code":"US","type":"facility","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I4210102457","https://openalex.org/I4210117453","https://openalex.org/I4210161994","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210161994","display_name":"Dana-Farber Brigham Cancer Center","ror":"https://ror.org/05rgrbr06","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I4210117453","https://openalex.org/I4210161994","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eudocia Q. Lee","raw_affiliation_strings":["Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, 450 Brookline Avenue, Boston, MA, 02215, USA","Center for Neuro-Oncology, Dana Farber/Brigham and Women's Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, 450 Brookline Avenue, Boston, MA, 02215, USA","institution_ids":["https://openalex.org/I4210102457","https://openalex.org/I4210161994"]},{"raw_affiliation_string":"Center for Neuro-Oncology, Dana Farber/Brigham and Women's Cancer Center","institution_ids":["https://openalex.org/I4210102457","https://openalex.org/I4210161994"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018451725","display_name":"Lakshmi Nayak","orcid":"https://orcid.org/0000-0003-2725-8717","observed_orcids":["https://orcid.org/0000-0003-2725-8717"]},"institutions":[{"id":"https://openalex.org/I4210102457","display_name":"Center for Neuro-Oncology","ror":"https://ror.org/00z2tp793","country_code":"US","type":"facility","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I4210102457","https://openalex.org/I4210117453","https://openalex.org/I4210161994","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210161994","display_name":"Dana-Farber Brigham Cancer Center","ror":"https://ror.org/05rgrbr06","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I4210117453","https://openalex.org/I4210161994","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lakshmi Nayak","raw_affiliation_strings":["Center for Neuro-Oncology, Dana-Farber/Brigham and Women\u2019s Cancer Center, 450 Brookline Avenue, Boston, MA, 02215, USA","Center for Neuro-Oncology, Dana Farber/Brigham and Women's Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neuro-Oncology, Dana-Farber/Brigham and Women\u2019s Cancer Center, 450 Brookline Avenue, Boston, MA, 02215, USA","institution_ids":["https://openalex.org/I4210102457","https://openalex.org/I4210161994"]},{"raw_affiliation_string":"Center for Neuro-Oncology, Dana Farber/Brigham and Women's Cancer Center","institution_ids":["https://openalex.org/I4210102457","https://openalex.org/I4210161994"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021656597","display_name":"Patrick Yung Wen","orcid":"https://orcid.org/0000-0002-0774-7700","observed_orcids":["https://orcid.org/0000-0002-0774-7700","https://orcid.org/0000-0003-3224-3042","https://orcid.org/0000-0002-2452-0540"]},"institutions":[{"id":"https://openalex.org/I4210102457","display_name":"Center for Neuro-Oncology","ror":"https://ror.org/00z2tp793","country_code":"US","type":"facility","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I4210102457","https://openalex.org/I4210117453","https://openalex.org/I4210161994","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210161994","display_name":"Dana-Farber Brigham Cancer Center","ror":"https://ror.org/05rgrbr06","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I4210117453","https://openalex.org/I4210161994","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick Y. Wen","raw_affiliation_strings":["Center for Neuro-Oncology, Dana-Farber/Brigham and Women\u2019s Cancer Center, 450 Brookline Avenue, Boston, MA, 02215, USA","Center for Neuro-Oncology, Dana Farber/Brigham and Women's Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neuro-Oncology, Dana-Farber/Brigham and Women\u2019s Cancer Center, 450 Brookline Avenue, Boston, MA, 02215, USA","institution_ids":["https://openalex.org/I4210102457","https://openalex.org/I4210161994"]},{"raw_affiliation_string":"Center for Neuro-Oncology, Dana Farber/Brigham and Women's Cancer Center","institution_ids":["https://openalex.org/I4210102457","https://openalex.org/I4210161994"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059965175","display_name":"David A. Reardon","orcid":"https://orcid.org/0000-0001-6674-0157","observed_orcids":["https://orcid.org/0000-0001-6674-0157"]},"institutions":[{"id":"https://openalex.org/I4210102457","display_name":"Center for Neuro-Oncology","ror":"https://ror.org/00z2tp793","country_code":"US","type":"facility","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I4210102457","https://openalex.org/I4210117453","https://openalex.org/I4210161994","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210161994","display_name":"Dana-Farber Brigham Cancer Center","ror":"https://ror.org/05rgrbr06","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I4210117453","https://openalex.org/I4210161994","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David A. Reardon","raw_affiliation_strings":["Center for Neuro-Oncology, Dana-Farber/Brigham and Women\u2019s Cancer Center, 450 Brookline Avenue, Boston, MA, 02215, USA","Center for Neuro-Oncology, Dana Farber/Brigham and Women's Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neuro-Oncology, Dana-Farber/Brigham and Women\u2019s Cancer Center, 450 Brookline Avenue, Boston, MA, 02215, USA","institution_ids":["https://openalex.org/I4210102457","https://openalex.org/I4210161994"]},{"raw_affiliation_string":"Center for Neuro-Oncology, Dana Farber/Brigham and Women's Cancer Center","institution_ids":["https://openalex.org/I4210102457","https://openalex.org/I4210161994"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5059965175"],"corresponding_institution_ids":["https://openalex.org/I4210102457","https://openalex.org/I4210161994"],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":null,"fwci":1.0354,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.74811321,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"15","issue":"3","first_page":"281","last_page":"288"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11914","display_name":"PARP inhibition in cancer therapy","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glioblastoma","display_name":"glioblastoma","score":0.9390000104904175},{"id":"https://openalex.org/keywords/newly-diagnosed-glioblastoma","display_name":"newly diagnosed glioblastoma","score":0.9869999885559082},{"id":"https://openalex.org/keywords/temozolomide","display_name":"temozolomide","score":0.8270000219345093},{"id":"https://openalex.org/keywords/chemoradiotherapy","display_name":"chemoradiotherapy","score":0.8029999732971191},{"id":"https://openalex.org/keywords/adjuvant-temozolomide","display_name":"adjuvant temozolomide","score":0.8360000252723694},{"id":"https://openalex.org/keywords/hypofractionated-radiotherapy","display_name":"hypofractionated radiotherapy","score":0.828000009059906},{"id":"https://openalex.org/keywords/elderly-patients","display_name":"elderly patients","score":0.8389999866485596},{"id":"https://openalex.org/keywords/bevacizumab","display_name":"bevacizumab","score":0.9570000171661377},{"id":"https://openalex.org/keywords/mgmt-promoter-status","display_name":"MGMT promoter status","score":0.9120000004768372},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.7580000162124634},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.8600000143051147}],"concepts":[{"id":"https://openalex.org/C2777389519","wikidata":"https://www.wikidata.org/wiki/Q425088","display_name":"Temozolomide","level":3,"score":0.9862943887710571},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9363769292831421},{"id":"https://openalex.org/C2777802072","wikidata":"https://www.wikidata.org/wiki/Q413299","display_name":"Bevacizumab","level":3,"score":0.890874981880188},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6221306920051575},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5869381427764893},{"id":"https://openalex.org/C2777863537","wikidata":"https://www.wikidata.org/wiki/Q357896","display_name":"Adjuvant","level":2,"score":0.5143845677375793},{"id":"https://openalex.org/C2776194525","wikidata":"https://www.wikidata.org/wiki/Q282142","display_name":"Glioblastoma","level":2,"score":0.505997359752655},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.45867806673049927},{"id":"https://openalex.org/C2780964509","wikidata":"https://www.wikidata.org/wiki/Q416975","display_name":"Dacarbazine","level":3,"score":0.4504748284816742},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4404239058494568},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.43316173553466797},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.271698534488678},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.06753876805305481}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/s11940-013-0226-9","doi":"https://doi.org/10.1007/s11940-013-0226-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11940-013-0226-9","pdf_url":null,"source":{"id":"https://openalex.org/S73587531","display_name":"Current Treatment Options in Neurology","issn_l":"1092-8480","issn":["1092-8480","1534-3138"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Treatment Options in Neurology","raw_type":"journal-article"},{"id":"pmid:23553038","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23553038","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current treatment options in neurology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.5899999737739563,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W196082818","https://openalex.org/W1544889021","https://openalex.org/W1855355791","https://openalex.org/W1972293641","https://openalex.org/W1991805542","https://openalex.org/W2002727873","https://openalex.org/W2011946822","https://openalex.org/W2020604769","https://openalex.org/W2043209332","https://openalex.org/W2074505661","https://openalex.org/W2083788852","https://openalex.org/W2084859122","https://openalex.org/W2096287682","https://openalex.org/W2100567246","https://openalex.org/W2103816610","https://openalex.org/W2107731988","https://openalex.org/W2111485768","https://openalex.org/W2125372543","https://openalex.org/W2133611748","https://openalex.org/W2133777904","https://openalex.org/W2139112748","https://openalex.org/W2148977460","https://openalex.org/W2154526619","https://openalex.org/W2158681922","https://openalex.org/W2159941636","https://openalex.org/W2162605078","https://openalex.org/W2162643152","https://openalex.org/W2162822594","https://openalex.org/W2164813836","https://openalex.org/W2279620401","https://openalex.org/W4242403727","https://openalex.org/W7073573211"],"related_works":["https://openalex.org/W2473819352","https://openalex.org/W2169869816","https://openalex.org/W2119925221","https://openalex.org/W2070226426","https://openalex.org/W4237783004","https://openalex.org/W2075981241","https://openalex.org/W2319724169","https://openalex.org/W2130852442","https://openalex.org/W606085651","https://openalex.org/W3139389455"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}