{"id":"https://openalex.org/W2017662460","doi":"https://doi.org/10.1016/s0940-2993(00)80017-2","title":"Immunopathological study on the development of swine serum-induced bile duct lesions in BALB/c and DBA/2 mice","display_name":"Immunopathological study on the development of swine serum-induced bile duct lesions in BALB/c and DBA/2 mice","publication_year":2000,"publication_date":"2000-03-01","ids":{"openalex":"https://openalex.org/W2017662460","doi":"https://doi.org/10.1016/s0940-2993(00)80017-2","mag":"2017662460","pmid":"https://pubmed.ncbi.nlm.nih.gov/10779153"},"language":"en","primary_location":{"id":"doi:10.1016/s0940-2993(00)80017-2","doi":"https://doi.org/10.1016/s0940-2993(00)80017-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0940-2993(00)80017-2","pdf_url":null,"source":{"id":"https://openalex.org/S93526581","display_name":"Experimental and Toxicologic Pathology","issn_l":"0940-2993","issn":["0940-2993","1618-1433"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and Toxicologic Pathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113010049","display_name":"Kazuhito Honjo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuhito Honjo","raw_affiliation_strings":["Department of Veterinary Pathology, Faculty of Agriculture, The University of Tokyo, Japan","Department of Veterinary Pathology, Faculty of Agriculture, the University of Tokyo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Pathology, Faculty of Agriculture, The University of Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]},{"raw_affiliation_string":"Department of Veterinary Pathology, Faculty of Agriculture, the University of Tokyo","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111726867","display_name":"Kunio Doi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kunio Doi","raw_affiliation_strings":["Department of Veterinary Pathology, Faculty of Agriculture, The University of Tokyo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Pathology, Faculty of Agriculture, The University of Tokyo","institution_ids":["https://openalex.org/I74801974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111726867"],"corresponding_institution_ids":["https://openalex.org/I74801974"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.16171944,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"52","issue":"1","first_page":"57","last_page":"65"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":0.37790000438690186,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":0.37790000438690186,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.3402999937534332,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11576","display_name":"IgG4-Related and Inflammatory Diseases","score":0.06859999895095825,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/swine-serum","display_name":"swine serum","score":0.718999981880188},{"id":"https://openalex.org/keywords/bile-duct-lesions","display_name":"bile duct lesions","score":0.9399999976158142},{"id":"https://openalex.org/keywords/immunopathology","display_name":"immunopathology","score":0.6480000019073486},{"id":"https://openalex.org/keywords/balb-c-mice","display_name":"BALB/c mice","score":0.8330000042915344},{"id":"https://openalex.org/keywords/dba-2-mice","display_name":"DBA/2 mice","score":1.0},{"id":"https://openalex.org/keywords/strain-differences","display_name":"strain differences","score":0.6209999918937683},{"id":"https://openalex.org/keywords/periductal-fibrosis","display_name":"periductal fibrosis","score":0.8560000061988831},{"id":"https://openalex.org/keywords/eosinophil-infiltration","display_name":"eosinophil infiltration","score":0.8140000104904175},{"id":"https://openalex.org/keywords/t-helper-cells","display_name":"T helper cells","score":0.8989999890327454},{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":0.8199999928474426},{"id":"https://openalex.org/keywords/plasma-cells","display_name":"plasma cells","score":0.6589999794960022},{"id":"https://openalex.org/keywords/immunoglobulin-deposition","display_name":"immunoglobulin deposition","score":0.5009999871253967}],"concepts":[{"id":"https://openalex.org/C2779777945","wikidata":"https://www.wikidata.org/wiki/Q851111","display_name":"Bile duct","level":2,"score":0.6381722688674927},{"id":"https://openalex.org/C153400128","wikidata":"https://www.wikidata.org/wiki/Q3150731","display_name":"Infiltration (HVAC)","level":2,"score":0.6260212659835815},{"id":"https://openalex.org/C2777562237","wikidata":"https://www.wikidata.org/wiki/Q835051","display_name":"Hyperplasia","level":2,"score":0.5921595096588135},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.5665087699890137},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5527089834213257},{"id":"https://openalex.org/C167414201","wikidata":"https://www.wikidata.org/wiki/Q1955391","display_name":"Muscle hypertrophy","level":2,"score":0.5144639015197754},{"id":"https://openalex.org/C2776529007","wikidata":"https://www.wikidata.org/wiki/Q9820","display_name":"BALB/c","level":3,"score":0.510749101638794},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5098606944084167},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.4861421287059784},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4781968593597412},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.46557968854904175},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.431942880153656},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3934239447116852},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2003026008605957},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000917","descriptor_name":"Antibody Formation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003135","descriptor_name":"Common Bile Duct","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D003137","descriptor_name":"Common Bile Duct Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003137","descriptor_name":"Common Bile Duct Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006965","descriptor_name":"Hyperplasia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007070","descriptor_name":"Immunoglobulin A","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007070","descriptor_name":"Immunoglobulin A","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007114","descriptor_name":"Immunization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008811","descriptor_name":"Mice, Inbred DBA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0940-2993(00)80017-2","doi":"https://doi.org/10.1016/s0940-2993(00)80017-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0940-2993(00)80017-2","pdf_url":null,"source":{"id":"https://openalex.org/S93526581","display_name":"Experimental and Toxicologic Pathology","issn_l":"0940-2993","issn":["0940-2993","1618-1433"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and Toxicologic Pathology","raw_type":"journal-article"},{"id":"pmid:10779153","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10779153","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W182860811","https://openalex.org/W199658846","https://openalex.org/W346035305","https://openalex.org/W1487280801","https://openalex.org/W1518494454","https://openalex.org/W1536070248","https://openalex.org/W1606369440","https://openalex.org/W1926875153","https://openalex.org/W1965860042","https://openalex.org/W1966064095","https://openalex.org/W1968871366","https://openalex.org/W1978349108","https://openalex.org/W1978867051","https://openalex.org/W1979296955","https://openalex.org/W1987386803","https://openalex.org/W2008246119","https://openalex.org/W2028798921","https://openalex.org/W2032336992","https://openalex.org/W2083504326","https://openalex.org/W2110288713","https://openalex.org/W2145310996","https://openalex.org/W2165294916","https://openalex.org/W2209593772","https://openalex.org/W2274565722","https://openalex.org/W2321107976","https://openalex.org/W2323643420","https://openalex.org/W2398205484","https://openalex.org/W2409849379","https://openalex.org/W2412577266","https://openalex.org/W2415416178","https://openalex.org/W2434996961","https://openalex.org/W2527390118","https://openalex.org/W4285719527","https://openalex.org/W6727499673"],"related_works":["https://openalex.org/W2165294916","https://openalex.org/W2412577266","https://openalex.org/W7047328314","https://openalex.org/W2299715939","https://openalex.org/W2336138979","https://openalex.org/W2417519588","https://openalex.org/W2323643420","https://openalex.org/W6989904773","https://openalex.org/W2430644326","https://openalex.org/W1967480132"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}