{"id":"https://openalex.org/W2017635447","doi":"https://doi.org/10.1016/j.jdiacomp.2012.10.009","title":"Association of the genetic variants of endothelial nitric oxide synthase gene with angiographically defined coronary artery disease and myocardial infarction in South Indian patients with type 2 diabetes mellitus","display_name":"Association of the genetic variants of endothelial nitric oxide synthase gene with angiographically defined coronary artery disease and myocardial infarction in South Indian patients with type 2 diabetes mellitus","publication_year":2012,"publication_date":"2012-11-20","ids":{"openalex":"https://openalex.org/W2017635447","doi":"https://doi.org/10.1016/j.jdiacomp.2012.10.009","mag":"2017635447","pmid":"https://pubmed.ncbi.nlm.nih.gov/23182401"},"language":"en","primary_location":{"id":"doi:10.1016/j.jdiacomp.2012.10.009","doi":"https://doi.org/10.1016/j.jdiacomp.2012.10.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jdiacomp.2012.10.009","pdf_url":null,"source":{"id":"https://openalex.org/S23257913","display_name":"Journal of Diabetes and its Complications","issn_l":"0891-6632","issn":["0891-6632","1056-8727","1873-460X","1878-0644"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Diabetes and its Complications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015239799","display_name":"Parimala Narne","orcid":"https://orcid.org/0000-0002-1582-6660","observed_orcids":["https://orcid.org/0000-0002-1582-6660"]},"institutions":[{"id":"https://openalex.org/I8975392","display_name":"Osmania University","ror":"https://ror.org/030sjb889","country_code":"IN","type":"education","lineage":["https://openalex.org/I8975392"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Parimala Narne","raw_affiliation_strings":["Department of Genetics, Osmania University, Hyderabad, 500 007, India. parimala_narne@yahoo.co.in","Department of Genetics Osmania University, Hyderabad-500 007, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Osmania University, Hyderabad, 500 007, India. parimala_narne@yahoo.co.in","institution_ids":["https://openalex.org/I8975392"]},{"raw_affiliation_string":"Department of Genetics Osmania University, Hyderabad-500 007, India","institution_ids":["https://openalex.org/I8975392"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113687281","display_name":"Kamakshi Chaithri Ponnaluri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8975392","display_name":"Osmania University","ror":"https://ror.org/030sjb889","country_code":"IN","type":"education","lineage":["https://openalex.org/I8975392"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Kamakshi Chaithri Ponnaluri","raw_affiliation_strings":["Department of Genetics, Osmania University, Hyderabad, 500 007, India","Department of Genetics Osmania University, Hyderabad-500 007, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Osmania University, Hyderabad, 500 007, India","institution_ids":["https://openalex.org/I8975392"]},{"raw_affiliation_string":"Department of Genetics Osmania University, Hyderabad-500 007, India","institution_ids":["https://openalex.org/I8975392"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113683142","display_name":"Shailender Singh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210127887","display_name":"Kamineni Hospitals","ror":"https://ror.org/02r0vmn14","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210127887"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Shailender Singh","raw_affiliation_strings":["Department of Cardiology, Kamineni Hospitals, Hyderabad, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Kamineni Hospitals, Hyderabad, India","institution_ids":["https://openalex.org/I4210127887"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101533326","display_name":"Siraj Mohammed","orcid":"https://orcid.org/0000-0003-0228-6068","observed_orcids":["https://orcid.org/0000-0003-0228-6068"]},"institutions":[{"id":"https://openalex.org/I149145351","display_name":"Deccan College of Medical Sciences","ror":"https://ror.org/02akmdw70","country_code":"IN","type":"education","lineage":["https://openalex.org/I149145351"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mohammed Siraj","raw_affiliation_strings":["Department of Medicine, Deccan College of Medical Sciences, Hyderabad, India","Department of Medicine; Deccan College of Medical Sciences; Hyderabad India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Deccan College of Medical Sciences, Hyderabad, India","institution_ids":["https://openalex.org/I149145351"]},{"raw_affiliation_string":"Department of Medicine; Deccan College of Medical Sciences; Hyderabad India","institution_ids":["https://openalex.org/I149145351"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108456273","display_name":"M Ishaq","orcid":"https://orcid.org/0009-0007-4322-5663","observed_orcids":["https://orcid.org/0009-0007-4322-5663"]},"institutions":[{"id":"https://openalex.org/I8975392","display_name":"Osmania University","ror":"https://ror.org/030sjb889","country_code":"IN","type":"education","lineage":["https://openalex.org/I8975392"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mohammed Ishaq","raw_affiliation_strings":["Department of Genetics, Osmania University, Hyderabad, 500 007, India","Department of Genetics Osmania University, Hyderabad-500 007, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Osmania University, Hyderabad, 500 007, India","institution_ids":["https://openalex.org/I8975392"]},{"raw_affiliation_string":"Department of Genetics Osmania University, Hyderabad-500 007, India","institution_ids":["https://openalex.org/I8975392"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5015239799"],"corresponding_institution_ids":["https://openalex.org/I8975392"],"apc_list":{"value":3760,"currency":"USD","value_usd":3760},"apc_paid":null,"fwci":1.1311,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.77426043,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"27","issue":"3","first_page":"255","last_page":"261"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.6464999914169312,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.6464999914169312,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.32739999890327454,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12975","display_name":"Paraoxonase enzyme and polymorphisms","score":0.011300000362098217,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endothelial-nitric-oxide-synthase","display_name":"endothelial nitric oxide synthase","score":0.9980000257492065},{"id":"https://openalex.org/keywords/enos-polymorphisms","display_name":"eNOS gene polymorphism","score":0.9679999947547913},{"id":"https://openalex.org/keywords/t-786c-polymorphism","display_name":"T-786C polymorphism","score":0.972000002861023},{"id":"https://openalex.org/keywords/enos-g894t-polymorphism","display_name":"G894T polymorphism","score":0.984000027179718},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.9940000176429749},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.9890000224113464},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9660000205039978},{"id":"https://openalex.org/keywords/three-vessel-coronary-artery-disease","display_name":"three-vessel coronary artery disease","score":0.8980000019073486},{"id":"https://openalex.org/keywords/macrovascular-disease","display_name":"macroangiopathy","score":0.6460000276565552},{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":0.9419999718666077},{"id":"https://openalex.org/keywords/linkage-disequilibrium","display_name":"linkage disequilibrium","score":0.8709999918937683},{"id":"https://openalex.org/keywords/south-indians","display_name":"South Indian population","score":0.8059999942779541}],"concepts":[{"id":"https://openalex.org/C2778326061","wikidata":"https://www.wikidata.org/wiki/Q1761022","display_name":"Enos","level":4,"score":0.8047769069671631},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.7419090867042542},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6343610882759094},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6103817820549011},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.5739349126815796},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.5427908897399902},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.528826892375946},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.5259029269218445},{"id":"https://openalex.org/C35605836","wikidata":"https://www.wikidata.org/wiki/Q2064311","display_name":"Linkage disequilibrium","level":5,"score":0.5065494775772095},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.45466935634613037},{"id":"https://openalex.org/C197754878","wikidata":"https://www.wikidata.org/wiki/Q80711","display_name":"Haplotype","level":4,"score":0.43285852670669556},{"id":"https://openalex.org/C37463918","wikidata":"https://www.wikidata.org/wiki/Q387981","display_name":"Allele frequency","level":4,"score":0.42986732721328735},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.4061565399169922},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3404802680015564},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.330898642539978},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27637553215026855},{"id":"https://openalex.org/C2777622882","wikidata":"https://www.wikidata.org/wiki/Q417619","display_name":"Nitric oxide synthase","level":3,"score":0.21412277221679688},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.1624961495399475},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16114556789398193}],"mesh":[{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003925","descriptor_name":"Diabetic Angiopathies","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003925","descriptor_name":"Diabetic Angiopathies","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003925","descriptor_name":"Diabetic Angiopathies","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003925","descriptor_name":"Diabetic Angiopathies","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003925","descriptor_name":"Diabetic Angiopathies","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003925","descriptor_name":"Diabetic Angiopathies","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003925","descriptor_name":"Diabetic Angiopathies","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003925","descriptor_name":"Diabetic Angiopathies","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003925","descriptor_name":"Diabetic Angiopathies","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007194","descriptor_name":"India","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007194","descriptor_name":"India","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007194","descriptor_name":"India","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007438","descriptor_name":"Introns","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007438","descriptor_name":"Introns","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007438","descriptor_name":"Introns","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015810","descriptor_name":"Linkage Disequilibrium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015810","descriptor_name":"Linkage Disequilibrium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015810","descriptor_name":"Linkage Disequilibrium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019943","descriptor_name":"Amino Acid Substitution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019943","descriptor_name":"Amino Acid Substitution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019943","descriptor_name":"Amino Acid Substitution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D052250","descriptor_name":"Nitric Oxide Synthase Type III","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D052250","descriptor_name":"Nitric Oxide Synthase Type III","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D052250","descriptor_name":"Nitric Oxide Synthase Type III","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D052250","descriptor_name":"Nitric Oxide Synthase Type III","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D052250","descriptor_name":"Nitric Oxide Synthase Type III","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D052250","descriptor_name":"Nitric Oxide Synthase Type III","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058065","descriptor_name":"Diabetic Cardiomyopathies","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D058065","descriptor_name":"Diabetic Cardiomyopathies","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D058065","descriptor_name":"Diabetic Cardiomyopathies","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D058065","descriptor_name":"Diabetic Cardiomyopathies","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D058065","descriptor_name":"Diabetic Cardiomyopathies","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D058065","descriptor_name":"Diabetic Cardiomyopathies","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jdiacomp.2012.10.009","doi":"https://doi.org/10.1016/j.jdiacomp.2012.10.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jdiacomp.2012.10.009","pdf_url":null,"source":{"id":"https://openalex.org/S23257913","display_name":"Journal of Diabetes and its Complications","issn_l":"0891-6632","issn":["0891-6632","1056-8727","1873-460X","1878-0644"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Diabetes and its Complications","raw_type":"journal-article"},{"id":"pmid:23182401","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23182401","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of diabetes and its complications","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.8199999928474426,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320721","display_name":"Council of Scientific and Industrial Research, India","ror":"https://ror.org/021wm7p51"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W1862838614","https://openalex.org/W1972561326","https://openalex.org/W1974332277","https://openalex.org/W1975258993","https://openalex.org/W1980325632","https://openalex.org/W1981923492","https://openalex.org/W1982065972","https://openalex.org/W1988800483","https://openalex.org/W1988870963","https://openalex.org/W1993387626","https://openalex.org/W1994269627","https://openalex.org/W1997956074","https://openalex.org/W1999762173","https://openalex.org/W2009609368","https://openalex.org/W2009731585","https://openalex.org/W2014813076","https://openalex.org/W2016833774","https://openalex.org/W2022377100","https://openalex.org/W2022459382","https://openalex.org/W2029491963","https://openalex.org/W2030447006","https://openalex.org/W2031320620","https://openalex.org/W2042699047","https://openalex.org/W2066213664","https://openalex.org/W2066519154","https://openalex.org/W2071186420","https://openalex.org/W2075178407","https://openalex.org/W2076795933","https://openalex.org/W2092509134","https://openalex.org/W2102641536","https://openalex.org/W2118418854","https://openalex.org/W2119093576","https://openalex.org/W2120174193","https://openalex.org/W2120402092","https://openalex.org/W2124905540","https://openalex.org/W2136203060","https://openalex.org/W2137760172","https://openalex.org/W2139579898","https://openalex.org/W2139583079","https://openalex.org/W2143293940","https://openalex.org/W2144428252","https://openalex.org/W2147534219","https://openalex.org/W2148637873","https://openalex.org/W2149887490","https://openalex.org/W2159819574","https://openalex.org/W2166322166","https://openalex.org/W2341272418","https://openalex.org/W2341645956","https://openalex.org/W2416703152","https://openalex.org/W4239027098"],"related_works":["https://openalex.org/W114349860","https://openalex.org/W2131092630","https://openalex.org/W2057413973","https://openalex.org/W2380977863","https://openalex.org/W2078792789","https://openalex.org/W2366069092","https://openalex.org/W2033791925","https://openalex.org/W4290290927","https://openalex.org/W2044539991","https://openalex.org/W1988134349"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}