{"id":"https://openalex.org/W2017593283","doi":"https://doi.org/10.1155/2014/250958","title":"Characterization of an Ovine Bilateral Critical Sized Bone Defect Iliac Wing Model to Examine Treatment Modalities Based on Bone Tissue Engineering","display_name":"Characterization of an Ovine Bilateral Critical Sized Bone Defect Iliac Wing Model to Examine Treatment Modalities Based on Bone Tissue Engineering","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2017593283","doi":"https://doi.org/10.1155/2014/250958","mag":"2017593283","pmid":"https://pubmed.ncbi.nlm.nih.gov/24696845","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3947786"},"language":"en","primary_location":{"id":"doi:10.1155/2014/250958","doi":"https://doi.org/10.1155/2014/250958","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2014/250958","pdf_url":"https://downloads.hindawi.com/journals/bmri/2014/250958.pdf","source":{"id":"https://openalex.org/S1010394304","display_name":"BioMed Research International","issn_l":"1110-7243","issn":["1110-7243","1110-7251","2314-6133","2314-6141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","medline","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioMed Research International","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/journals/bmri/2014/250958.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030897429","display_name":"Jennifer L. Lansdowne","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24616306","display_name":"AO Foundation","ror":"https://ror.org/04v7vb598","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I24616306"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Jennifer L. Lansdowne","raw_affiliation_strings":["AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland","institution_ids":["https://openalex.org/I24616306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006867851","display_name":"Declan M. Devine","orcid":"https://orcid.org/0000-0002-1364-5583","observed_orcids":["https://orcid.org/0000-0002-1364-5583"]},"institutions":[{"id":"https://openalex.org/I24616306","display_name":"AO Foundation","ror":"https://ror.org/04v7vb598","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I24616306"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Declan Devine","raw_affiliation_strings":["AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-1364-5583","affiliations":[{"raw_affiliation_string":"AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland","institution_ids":["https://openalex.org/I24616306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069932943","display_name":"Ursula Eberli","orcid":"https://orcid.org/0000-0002-7635-1849","observed_orcids":["https://orcid.org/0000-0002-7635-1849"]},"institutions":[{"id":"https://openalex.org/I24616306","display_name":"AO Foundation","ror":"https://ror.org/04v7vb598","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I24616306"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Ursula Eberli","raw_affiliation_strings":["AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland","institution_ids":["https://openalex.org/I24616306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085736490","display_name":"Pieter J. Emans","orcid":"https://orcid.org/0000-0001-9370-5525","observed_orcids":["https://orcid.org/0000-0001-9370-5525"]},"institutions":[{"id":"https://openalex.org/I2800191616","display_name":"Maastricht University Medical Centre","ror":"https://ror.org/02d9ce178","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800191616"]},{"id":"https://openalex.org/I4405268545","display_name":"Care and Public Health Research Institute","ror":"https://ror.org/01930wn69","country_code":"NL","type":"facility","lineage":["https://openalex.org/I34352273","https://openalex.org/I4405268545"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Pieter Emans","raw_affiliation_strings":["Department of Orthopaedic Surgery, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Centre, 6202 AZ Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Centre, 6202 AZ Maastricht, The Netherlands","institution_ids":["https://openalex.org/I2800191616","https://openalex.org/I4405268545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014369135","display_name":"Tim J. M. Welting","orcid":"https://orcid.org/0000-0001-8081-4466","observed_orcids":["https://orcid.org/0000-0001-8081-4466"]},"institutions":[{"id":"https://openalex.org/I2800191616","display_name":"Maastricht University Medical Centre","ror":"https://ror.org/02d9ce178","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800191616"]},{"id":"https://openalex.org/I4405268545","display_name":"Care and Public Health Research Institute","ror":"https://ror.org/01930wn69","country_code":"NL","type":"facility","lineage":["https://openalex.org/I34352273","https://openalex.org/I4405268545"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Tim J. M. Welting","raw_affiliation_strings":["Department of Orthopaedic Surgery, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Centre, 6202 AZ Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Centre, 6202 AZ Maastricht, The Netherlands","institution_ids":["https://openalex.org/I2800191616","https://openalex.org/I4405268545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079966204","display_name":"Jim C. E. Odekerken","orcid":"https://orcid.org/0000-0001-9745-0005","observed_orcids":["https://orcid.org/0000-0001-9745-0005"]},"institutions":[{"id":"https://openalex.org/I2800191616","display_name":"Maastricht University Medical Centre","ror":"https://ror.org/02d9ce178","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800191616"]},{"id":"https://openalex.org/I4405268545","display_name":"Care and Public Health Research Institute","ror":"https://ror.org/01930wn69","country_code":"NL","type":"facility","lineage":["https://openalex.org/I34352273","https://openalex.org/I4405268545"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jim C. E. Odekerken","raw_affiliation_strings":["Department of Orthopaedic Surgery, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Centre, 6202 AZ Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Centre, 6202 AZ Maastricht, The Netherlands","institution_ids":["https://openalex.org/I2800191616","https://openalex.org/I4405268545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005542741","display_name":"Damiano Schiuma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24616306","display_name":"AO Foundation","ror":"https://ror.org/04v7vb598","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I24616306"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Damiano Schiuma","raw_affiliation_strings":["AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland","institution_ids":["https://openalex.org/I24616306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062909104","display_name":"Martin Thalhauser","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24616306","display_name":"AO Foundation","ror":"https://ror.org/04v7vb598","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I24616306"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Martin Thalhauser","raw_affiliation_strings":["AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland","institution_ids":["https://openalex.org/I24616306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108361870","display_name":"Ludovic P. Bour\u00e9","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24616306","display_name":"AO Foundation","ror":"https://ror.org/04v7vb598","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I24616306"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Ludovic Bour\u00e9","raw_affiliation_strings":["AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland","institution_ids":["https://openalex.org/I24616306"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080025256","display_name":"Stephan Zeiter","orcid":"https://orcid.org/0000-0002-8155-4202","observed_orcids":["https://orcid.org/0000-0002-8155-4202"]},"institutions":[{"id":"https://openalex.org/I24616306","display_name":"AO Foundation","ror":"https://ror.org/04v7vb598","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I24616306"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Stephan Zeiter","raw_affiliation_strings":["AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-8155-4202","affiliations":[{"raw_affiliation_string":"AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland","institution_ids":["https://openalex.org/I24616306"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5080025256"],"corresponding_institution_ids":["https://openalex.org/I24616306"],"apc_list":{"value":2680,"currency":"USD","value_usd":2680},"apc_paid":{"value":2680,"currency":"USD","value_usd":2680},"fwci":0.6073,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.65345875,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"2014","issue":null,"first_page":"1","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10658","display_name":"Bone fractures and treatments","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/critical-sized-bone-defects","display_name":"critical-size bone defect","score":0.9449999928474426},{"id":"https://openalex.org/keywords/bone-tissue-engineering","display_name":"bone tissue engineering","score":0.8320000171661377},{"id":"https://openalex.org/keywords/sheep-model","display_name":"sheep model","score":0.859000027179718},{"id":"https://openalex.org/keywords/iliac-wing","display_name":"iliac wing","score":0.8550000190734863},{"id":"https://openalex.org/keywords/autologous-bone-graft","display_name":"autologous bone graft","score":0.8579999804496765},{"id":"https://openalex.org/keywords/bone-regeneration","display_name":"bone regeneration","score":0.8339999914169312},{"id":"https://openalex.org/keywords/bone-volume","display_name":"bone volume","score":0.800000011920929},{"id":"https://openalex.org/keywords/histomorphometry","display_name":"histomorphometry","score":0.8320000171661377},{"id":"https://openalex.org/keywords/fluorescent-labeling","display_name":"fluorescent labeling","score":0.6549999713897705},{"id":"https://openalex.org/keywords/large-animal-model","display_name":"large animal model","score":0.5590000152587891}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6407708525657654},{"id":"https://openalex.org/C2779903281","wikidata":"https://www.wikidata.org/wiki/Q6888026","display_name":"Modalities","level":2,"score":0.5366826057434082},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.45471712946891785},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.44397637248039246},{"id":"https://openalex.org/C40993552","wikidata":"https://www.wikidata.org/wiki/Q514654","display_name":"Gold standard (test)","level":2,"score":0.43859168887138367},{"id":"https://openalex.org/C8337478","wikidata":"https://www.wikidata.org/wiki/Q1777289","display_name":"Bone healing","level":2,"score":0.4344903528690338},{"id":"https://openalex.org/C57742111","wikidata":"https://www.wikidata.org/wiki/Q7168","display_name":"Histology","level":2,"score":0.42702895402908325},{"id":"https://openalex.org/C3020606620","wikidata":"https://www.wikidata.org/wiki/Q179661","display_name":"Treatment modality","level":2,"score":0.4180492162704468},{"id":"https://openalex.org/C2778606738","wikidata":"https://www.wikidata.org/wiki/Q265868","display_name":"Bone tissue","level":2,"score":0.4155169129371643},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3904808461666107},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.37075257301330566},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.2884465456008911},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.28290897607803345},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15161165595054626},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007085","descriptor_name":"Ilium","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D007085","descriptor_name":"Ilium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D007085","descriptor_name":"Ilium","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009929","descriptor_name":"Organ Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015519","descriptor_name":"Bone Density","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055114","descriptor_name":"X-Ray Microtomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1155/2014/250958","doi":"https://doi.org/10.1155/2014/250958","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2014/250958","pdf_url":"https://downloads.hindawi.com/journals/bmri/2014/250958.pdf","source":{"id":"https://openalex.org/S1010394304","display_name":"BioMed Research International","issn_l":"1110-7243","issn":["1110-7243","1110-7251","2314-6133","2314-6141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","medline","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioMed Research International","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2955111","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3947786","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3947786","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3947786","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomed Res Int","raw_type":"Text"},{"id":"pmid:24696845","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24696845","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioMed research international","raw_type":"Journal Article"},{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire/33045141-c046-444e-8f44-75638dc901b9","doi":null,"is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/33045141-c046-444e-8f44-75638dc901b9","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lansdowne, J L, Devine, D, Eberli, U, Emans, P, Welting, T J M, Odekerken, J C E, Schiuma, D, Thalhauser, M, Bour\u00e9, L & Zeiter, S 2014, 'Characterization of an Ovine Bilateral Critical Sized Bone Defect Iliac Wing Model to Examine Treatment Modalities Based on Bone Tissue Engineering', BioMed Research International, vol. 2014, 250958. https://doi.org/10.1155/2014/250958","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:4b0a122fc82f48bbb3a35558213ed90f","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/4b0a122fc82f48bbb3a35558213ed90f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BioMed Research International, Vol 2014 (2014)","raw_type":"article"},{"id":"pmh:um:oai:cris.maastrichtuniversity.nl:publications/33045141-c046-444e-8f44-75638dc901b9","doi":null,"is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/33045141-c046-444e-8f44-75638dc901b9","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BioMed Research International, 2014:250958. Hindawi Publishing Corporation","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1155/2014/250958","doi":"https://doi.org/10.1155/2014/250958","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2014/250958","pdf_url":"https://downloads.hindawi.com/journals/bmri/2014/250958.pdf","source":{"id":"https://openalex.org/S1010394304","display_name":"BioMed Research International","issn_l":"1110-7243","issn":["1110-7243","1110-7251","2314-6133","2314-6141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","medline","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioMed Research International","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2017593283.pdf","grobid_xml":"https://content.openalex.org/works/W2017593283.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W1238924260","https://openalex.org/W1978666896","https://openalex.org/W1995946343","https://openalex.org/W1999698419","https://openalex.org/W2007310752","https://openalex.org/W2035133444","https://openalex.org/W2043070543","https://openalex.org/W2050007266","https://openalex.org/W2059905814","https://openalex.org/W2083925767","https://openalex.org/W2113335122","https://openalex.org/W2157317927","https://openalex.org/W2158131612","https://openalex.org/W2187544091","https://openalex.org/W2262174235","https://openalex.org/W4255830556"],"related_works":["https://openalex.org/W7097428954","https://openalex.org/W6964771665","https://openalex.org/W2128040041","https://openalex.org/W3006287442","https://openalex.org/W1978255604","https://openalex.org/W2024451442","https://openalex.org/W2081219815","https://openalex.org/W4224304974","https://openalex.org/W4402130909","https://openalex.org/W2337581535"],"abstract_inverted_index":{"Critical":[0],"sized":[1],"bone":[2,22,63,77,97,146,185],"defect":[3,67,100,107],"(CSBD)":[4],"animal":[5,58],"models":[6],"are":[7],"used":[8,174],"to":[9,114],"evaluate":[10],"and":[11,14,90,162],"confirm":[12],"efficacy":[13],"potency":[15],"of":[16,45,117,179],"new":[17,96,145,180],"treatment":[18,181],"modalities":[19,182],"based":[20,183],"on":[21,184],"tissue":[23,186],"engineering":[24],"before":[25],"the":[26,42,66,99,105,109,115,118,121,127,135,139],"latter":[27,140],"can":[28,172],"be":[29,173],"applied":[30],"in":[31,41,49,61,108,120,126,134,166,176],"clinical":[32],"practice.":[33],"In":[34],"this":[35,54],"study,":[36],"a":[37,56,160],"bilateral":[38,164],"CSBD":[39,59,165],"model":[40,60,156],"iliac":[43],"wings":[44],"sheep":[46,167],"is":[47,55],"described":[48,157],"detail.":[50],"To":[51],"demonstrate":[52],"that":[53,171],"large":[57],"sheep,":[62],"healing":[64],"within":[65],"left":[68],"empty":[69],"(negative":[70],"control)":[71,83],"or":[72,152],"filled":[73],"with":[74,138,168],"autologous":[75],"corticocancellous":[76],"graft":[78],"(clinical":[79],"gold":[80],"standard,":[81],"positive":[82,110,128],"was":[84,102,130],"assessed":[85],"using":[86],"micro-CT,":[87],"histology,":[88],"histomorphometric,":[89],"fluorochrome":[91],"analysis.":[92],"After":[93],"three":[94],"months,":[95],"into":[98],"site":[101],"formed":[103],"across":[104],"whole":[106],"controls":[111,129],"but":[112],"limited":[113],"edge":[116],"defects":[119],"negative":[122,136],"controls.":[123],"Bone":[124],"volume":[125],"statistically":[131],"higher":[132],"than":[133,143],"controls,":[137],"having":[141],"less":[142],"10%":[144],"growth.":[147],"There":[148],"were":[149],"no":[150],"intraoperative":[151],"postoperative":[153],"complications.":[154],"The":[155],"here":[158],"represents":[159],"reliable":[161],"reproducible":[163],"low":[169],"morbidity":[170],"for":[175],"vivo":[177],"evaluation":[178],"engineering.":[187]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}