{"id":"https://openalex.org/W2017590089","doi":"https://doi.org/10.1523/jneurosci.4511-09.2010","title":"Nitric Oxide Acts as a Volume Transmitter to Modulate Electrical Properties of Spontaneously Firing Neurons via Apamin-Sensitive Potassium Channels","display_name":"Nitric Oxide Acts as a Volume Transmitter to Modulate Electrical Properties of Spontaneously Firing Neurons via Apamin-Sensitive Potassium Channels","publication_year":2010,"publication_date":"2010-02-03","ids":{"openalex":"https://openalex.org/W2017590089","doi":"https://doi.org/10.1523/jneurosci.4511-09.2010","mag":"2017590089","pmid":"https://pubmed.ncbi.nlm.nih.gov/20130179","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6633990"},"language":"en","primary_location":{"id":"doi:10.1523/jneurosci.4511-09.2010","doi":"https://doi.org/10.1523/jneurosci.4511-09.2010","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.4511-09.2010","pdf_url":"https://www.jneurosci.org/content/jneuro/30/5/1699.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.jneurosci.org/content/jneuro/30/5/1699.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000971683","display_name":"Liana R. Artinian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Liana Artinian","raw_affiliation_strings":["Department of Biology, Georgia State University, Atlanta, Georgia 30302-4010, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Georgia State University, Atlanta, Georgia 30302-4010, USA","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017375440","display_name":"Karine Tornieri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karine Tornieri","raw_affiliation_strings":["Department of Biology, Georgia State University, Atlanta, Georgia 30302-4010","Department of Biology and Neuroscience Institute, Georgia State University, P.O. Box 4010, Atlanta, GA 30302-4010","Department of Cell Biology, Emory University, Atlanta, GA 30322"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Georgia State University, Atlanta, Georgia 30302-4010","institution_ids":["https://openalex.org/I181565077"]},{"raw_affiliation_string":"Department of Biology and Neuroscience Institute, Georgia State University, P.O. Box 4010, Atlanta, GA 30302-4010","institution_ids":["https://openalex.org/I181565077"]},{"raw_affiliation_string":"Department of Cell Biology, Emory University, Atlanta, GA 30322","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019249919","display_name":"Lei Ray Zhong","orcid":"https://orcid.org/0000-0002-5035-7919","observed_orcids":["https://orcid.org/0000-0002-5035-7919"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lei Zhong","raw_affiliation_strings":["Department of Biology, Georgia State University, Atlanta, Georgia 30302-4010","Department of Cell Biology, Emory University, Atlanta, GA 30322","Department of Biology and Neuroscience Institute, Georgia State University, P.O. Box 4010, Atlanta, GA 30302-4010"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Georgia State University, Atlanta, Georgia 30302-4010","institution_ids":["https://openalex.org/I181565077"]},{"raw_affiliation_string":"Department of Cell Biology, Emory University, Atlanta, GA 30322","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Biology and Neuroscience Institute, Georgia State University, P.O. Box 4010, Atlanta, GA 30302-4010","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023209166","display_name":"Deborah J. Baro","orcid":"https://orcid.org/0000-0002-7741-4055","observed_orcids":["https://orcid.org/0000-0002-7741-4055"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deborah Baro","raw_affiliation_strings":["Department of Biology, Georgia State University, Atlanta, Georgia 30302-4010","Department of Biology and Neuroscience Institute, Georgia State University, P.O. Box 4010, Atlanta, GA 30302-4010","Department of Cell Biology, Emory University, Atlanta, GA 30322"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Georgia State University, Atlanta, Georgia 30302-4010","institution_ids":["https://openalex.org/I181565077"]},{"raw_affiliation_string":"Department of Biology and Neuroscience Institute, Georgia State University, P.O. Box 4010, Atlanta, GA 30302-4010","institution_ids":["https://openalex.org/I181565077"]},{"raw_affiliation_string":"Department of Cell Biology, Emory University, Atlanta, GA 30322","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023017241","display_name":"Vincent Rehder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Vincent Rehder","raw_affiliation_strings":["Department of Biology, Georgia State University, Atlanta, Georgia 30302-4010","Department of Biology and Neuroscience Institute, Georgia State University, P.O. Box 4010, Atlanta, GA 30302-4010","Department of Cell Biology, Emory University, Atlanta, GA 30322"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Georgia State University, Atlanta, Georgia 30302-4010","institution_ids":["https://openalex.org/I181565077"]},{"raw_affiliation_string":"Department of Biology and Neuroscience Institute, Georgia State University, P.O. Box 4010, Atlanta, GA 30302-4010","institution_ids":["https://openalex.org/I181565077"]},{"raw_affiliation_string":"Department of Cell Biology, Emory University, Atlanta, GA 30322","institution_ids":["https://openalex.org/I150468666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5023017241"],"corresponding_institution_ids":["https://openalex.org/I150468666","https://openalex.org/I181565077"],"apc_list":null,"apc_paid":null,"fwci":1.562,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.811801,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"30","issue":"5","first_page":"1699","last_page":"1711"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.8817999958992004,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.8817999958992004,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.09269999712705612,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.009200000204145908,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.9990000128746033},{"id":"https://openalex.org/keywords/apamin-sensitive-potassium-channels","display_name":"apamin-sensitive potassium channels","score":0.890999972820282},{"id":"https://openalex.org/keywords/neuronal-excitability","display_name":"neuronal excitability","score":0.9660000205039978},{"id":"https://openalex.org/keywords/membrane-depolarization","display_name":"membrane depolarization","score":0.8370000123977661},{"id":"https://openalex.org/keywords/neuronal-firing-rate","display_name":"neuronal firing rate","score":0.8669999837875366},{"id":"https://openalex.org/keywords/neuronal-silencing","display_name":"neuronal silencing","score":0.9860000014305115},{"id":"https://openalex.org/keywords/helisoma-trivolvis","display_name":"Helisoma trivolvis","score":0.8659999966621399},{"id":"https://openalex.org/keywords/nitric-oxide-donors","display_name":"nitric oxide donors","score":0.7080000042915344},{"id":"https://openalex.org/keywords/mollusk-neurons","display_name":"mollusk neurons","score":0.5649999976158142},{"id":"https://openalex.org/keywords/neurite-outgrowth","display_name":"neurite outgrowth","score":0.8019999861717224},{"id":"https://openalex.org/keywords/brain-development","display_name":"brain development","score":0.9380000233650208}],"concepts":[{"id":"https://openalex.org/C2776919887","wikidata":"https://www.wikidata.org/wiki/Q417260","display_name":"Apamin","level":3,"score":0.966439962387085},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.7254490256309509},{"id":"https://openalex.org/C83743174","wikidata":"https://www.wikidata.org/wiki/Q423778","display_name":"Potassium channel","level":2,"score":0.6976300477981567},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5617699027061462},{"id":"https://openalex.org/C149786707","wikidata":"https://www.wikidata.org/wiki/Q7390712","display_name":"SK channel","level":4,"score":0.5271461009979248},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.46692773699760437},{"id":"https://openalex.org/C517785266","wikidata":"https://www.wikidata.org/wiki/Q703","display_name":"Potassium","level":2,"score":0.445026159286499},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4213590621948242},{"id":"https://openalex.org/C2778457506","wikidata":"https://www.wikidata.org/wiki/Q7234689","display_name":"Potassium channel blocker","level":3,"score":0.41507506370544434},{"id":"https://openalex.org/C50254741","wikidata":"https://www.wikidata.org/wiki/Q62536","display_name":"Ion channel","level":3,"score":0.3032556474208832},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15061432123184204},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09870553016662598},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001030","descriptor_name":"Apamin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006834","descriptor_name":"Hydrazines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012908","descriptor_name":"Snails","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015220","descriptor_name":"Calcium Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015221","descriptor_name":"Potassium Channels","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015221","descriptor_name":"Potassium Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017952","descriptor_name":"Ganglia, Invertebrate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019001","descriptor_name":"Nitric Oxide Synthase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019001","descriptor_name":"Nitric Oxide Synthase","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020030","descriptor_name":"Nitric Oxide Donors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D020439","descriptor_name":"Growth Cones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020439","descriptor_name":"Growth Cones","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D051640","descriptor_name":"Small-Conductance Calcium-Activated Potassium Channels","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D051640","descriptor_name":"Small-Conductance Calcium-Activated Potassium Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1523/jneurosci.4511-09.2010","doi":"https://doi.org/10.1523/jneurosci.4511-09.2010","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.4511-09.2010","pdf_url":"https://www.jneurosci.org/content/jneuro/30/5/1699.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6633990","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6633990","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Neurosci","raw_type":"Text"},{"id":"pmid:20130179","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20130179","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of neuroscience : the official journal of the Society for Neuroscience","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1523/jneurosci.4511-09.2010","doi":"https://doi.org/10.1523/jneurosci.4511-09.2010","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.4511-09.2010","pdf_url":"https://www.jneurosci.org/content/jneuro/30/5/1699.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation","score":0.4099999964237213}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1447390033","display_name":"Nitric Oxide as an Inter- and  Intracellular Messenger in Growth Cones","funder_award_id":"0343096","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G1828212037","display_name":"Nitric oxide as cell-intrinsic messenger of neuronal function","funder_award_id":"0843173","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320310607","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2017590089.pdf","grobid_xml":"https://content.openalex.org/works/W2017590089.grobid-xml"},"referenced_works_count":62,"referenced_works":["https://openalex.org/W49083090","https://openalex.org/W1490928475","https://openalex.org/W1496458048","https://openalex.org/W1511814572","https://openalex.org/W1518092848","https://openalex.org/W1592332292","https://openalex.org/W1603471307","https://openalex.org/W1852853462","https://openalex.org/W1922547393","https://openalex.org/W1963957029","https://openalex.org/W1965772734","https://openalex.org/W1974603954","https://openalex.org/W1978648371","https://openalex.org/W1983997675","https://openalex.org/W1984084346","https://openalex.org/W1985172143","https://openalex.org/W1991267134","https://openalex.org/W1991673195","https://openalex.org/W1992371433","https://openalex.org/W1996196738","https://openalex.org/W1999514642","https://openalex.org/W2004923981","https://openalex.org/W2005455038","https://openalex.org/W2006819627","https://openalex.org/W2008384189","https://openalex.org/W2013861261","https://openalex.org/W2022023838","https://openalex.org/W2022425569","https://openalex.org/W2024169215","https://openalex.org/W2032278170","https://openalex.org/W2033849297","https://openalex.org/W2035918801","https://openalex.org/W2040329696","https://openalex.org/W2042670053","https://openalex.org/W2046308113","https://openalex.org/W2047788980","https://openalex.org/W2047985837","https://openalex.org/W2051106202","https://openalex.org/W2059743066","https://openalex.org/W2061207726","https://openalex.org/W2061942188","https://openalex.org/W2070763844","https://openalex.org/W2071698136","https://openalex.org/W2074964109","https://openalex.org/W2078335821","https://openalex.org/W2079993632","https://openalex.org/W2082606088","https://openalex.org/W2089556282","https://openalex.org/W2098381765","https://openalex.org/W2103769608","https://openalex.org/W2111070504","https://openalex.org/W2119147857","https://openalex.org/W2136142112","https://openalex.org/W2138270403","https://openalex.org/W2144205676","https://openalex.org/W2144941698","https://openalex.org/W2154575221","https://openalex.org/W2156148823","https://openalex.org/W2170840355","https://openalex.org/W2214256977","https://openalex.org/W2317585517","https://openalex.org/W4250910443"],"related_works":["https://openalex.org/W2059096125","https://openalex.org/W2133246257","https://openalex.org/W2033343289","https://openalex.org/W2040329696","https://openalex.org/W7097686278","https://openalex.org/W2043790997","https://openalex.org/W7171269281","https://openalex.org/W3164255743","https://openalex.org/W1969738234","https://openalex.org/W1984956427"],"abstract_inverted_index":{"Nitric":[0],"oxide":[1],"(NO)":[2],"is":[3],"a":[4,7,24,42,196,247],"radical":[5],"and":[6,17,47,92,108,203,228],"gas,":[8],"properties":[9],"that":[10,73,129,148,210],"allow":[11],"NO":[12,39,51,55,59,66,74,100,124,136,155,171,176,184,199,211,244],"to":[13,21,33,49,156,170,215],"diffuse":[14],"through":[15],"membranes":[16],"potentially":[18],"enable":[19],"it":[20],"function":[22],"as":[23,41,246],"\"volume":[25],"messenger.\"":[26],"This":[27],"study":[28],"had":[29],"two":[30],"goals:":[31],"first,":[32],"investigate":[34],"the":[35,76,83,130,158,174,181,207,213,217,220,235,241],"mechanisms":[36],"by":[37,54,64,103,223],"which":[38],"functions":[40],"modulator":[43],"of":[44,79,82,99,105,115,123,132,135,141,154,161,183,188,219,237,243],"neuronal":[45,95,189],"excitability,":[46],"second,":[48],"compare":[50],"effects":[52,98,122,134,167],"produced":[53],"release":[56,67,151,172],"from":[57,68,173],"chemical":[58,175],"donors":[60,185],"with":[61,192],"those":[62],"elicited":[63],"physiological":[65],"single":[69,149],"neurons.":[70],"We":[71,145],"demonstrate":[72],"depolarizes":[75],"membrane":[77],"potential":[78,214],"B5":[80,162],"neurons":[81,150,163,232],"mollusk":[84],"Helisoma":[85],"trivolvis,":[86],"initially":[87],"increasing":[88],"their":[89],"firing":[90,126],"rate":[91],"later":[93],"causing":[94],"silencing.":[96],"Both":[97],"were":[101],"mediated":[102,138],"inhibition":[104,114,140],"Ca-activated":[106],"iberiotoxin-":[107],"apamin-sensitive":[109,116,142],"K":[110,117,143],"channels,":[111],"but":[112],"only":[113],"channels":[118],"fully":[119],"mimicked":[120],"all":[121],"on":[125],"activity,":[127],"suggesting":[128],"majority":[131],"electrical":[133,159,226],"are":[137,168],"via":[139],"channels.":[144],"further":[146],"show":[147],"sufficient":[152],"amounts":[153],"affect":[157],"activity":[160,227],"located":[164,233],"nearby.":[165],"These":[166],"similar":[169],"donor":[177],"NOC-7":[178],"[3-(2-hydroxy-1-methyl-2-nitrosohydazino)-N-methyl-1-propyanamine],":[179],"validating":[180],"use":[182],"in":[186,200,231,234],"studies":[187],"excitability.":[190],"Together":[191],"previous":[193],"findings":[194],"demonstrating":[195],"role":[197],"for":[198],"neurite":[201,229],"outgrowth":[202,230],"growth":[204],"cone":[205],"motility,":[206],"results":[208],"suggest":[209],"has":[212],"shape":[216],"development":[218],"nervous":[221],"system":[222],"modulating":[224],"both":[225],"vicinity":[236],"NO-producing":[238],"cells,":[239],"supporting":[240],"notion":[242],"functioning":[245],"volume":[248],"messenger.":[249]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}