{"id":"https://openalex.org/W2017559797","doi":"https://doi.org/10.1227/01.neu.0000156493.00904.7e","title":"Erythropoietin and Erythropoietin Receptor Expression after Experimental Spinal Cord Injury Encourages Therapy by Exogenous Erythropoietin","display_name":"Erythropoietin and Erythropoietin Receptor Expression after Experimental Spinal Cord Injury Encourages Therapy by Exogenous Erythropoietin","publication_year":2005,"publication_date":"2005-03-29","ids":{"openalex":"https://openalex.org/W2017559797","doi":"https://doi.org/10.1227/01.neu.0000156493.00904.7e","mag":"2017559797","pmid":"https://pubmed.ncbi.nlm.nih.gov/15792521"},"language":"en","primary_location":{"id":"doi:10.1227/01.neu.0000156493.00904.7e","doi":"https://doi.org/10.1227/01.neu.0000156493.00904.7e","is_oa":false,"landing_page_url":"https://doi.org/10.1227/01.neu.0000156493.00904.7e","pdf_url":null,"source":{"id":"https://openalex.org/S111727011","display_name":"Neurosurgery","issn_l":"0148-396X","issn":["0148-396X","1081-1281","1524-4040"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurosurgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061049828","display_name":"Giovanni Grasso","orcid":"https://orcid.org/0000-0001-5362-0092","observed_orcids":["https://orcid.org/0000-0001-5362-0092","https://orcid.org/0000-0002-8246-0283"]},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giovanni Grasso","raw_affiliation_strings":["Department of Neurosurgery, University of Messina, Messina, Italy","Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, University of Messina, Messina, Italy","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083609130","display_name":"Alessandra Sfacteria","orcid":"https://orcid.org/0000-0003-3671-3750","observed_orcids":["https://orcid.org/0000-0003-3671-3750"]},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandra Sfacteria","raw_affiliation_strings":["Department of Veterinary Pathology, University of Messina, Messina, Italy","Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Pathology, University of Messina, Messina, Italy","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103411447","display_name":"Marcello Passalacqua","orcid":"https://orcid.org/0000-0003-3305-7698","observed_orcids":["https://orcid.org/0000-0003-3305-7698"]},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marcello Passalacqua","raw_affiliation_strings":["Department of Neurosurgery, University of Messina, Messina, Italy","Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, University of Messina, Messina, Italy","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Antonio Morabito","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonio Morabito","raw_affiliation_strings":["Department of Neurosurgery, University of Messina, Messina, Italy","Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, University of Messina, Messina, Italy","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108079589","display_name":"Michele Buemi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Michele Buemi","raw_affiliation_strings":["Department of Internal Medicine, University of Messina, Messina, Italy","Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, University of Messina, Messina, Italy","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047082032","display_name":"B Macr\u00ec","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Battesimo Macr\u00ec","raw_affiliation_strings":["Department of Veterinary Pathology, University of Messina, Messina, Italy","Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Pathology, University of Messina, Messina, Italy","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029709460","display_name":"Michael L. Brines","orcid":"https://orcid.org/0000-0003-4151-4449","observed_orcids":["https://orcid.org/0000-0003-4151-4449"]},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Michael L. Brines","raw_affiliation_strings":["The Kenneth S. Warren Institute, New York, New York","Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Kenneth S. Warren Institute, New York, New York","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048428897","display_name":"Francesco F. Tomasello","orcid":"https://orcid.org/0000-0003-1435-3598","observed_orcids":["https://orcid.org/0000-0003-1435-3598"]},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesco Tomasello","raw_affiliation_strings":["Department of Neurosurgery, University of Messina, Messina, Italy","Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, University of Messina, Messina, Italy","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Internal Medicine, University of Messina, Messina, Italy (Buemi)","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Department of Neurosurgery, University of Messina, Messina, Italy (Grasso, Passalacqua, Morabito, Tomasello)","institution_ids":["https://openalex.org/I112862951"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I112862951"],"apc_list":null,"apc_paid":null,"fwci":4.4074,"has_fulltext":false,"cited_by_count":68,"citation_normalized_percentile":{"value":0.94588511,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"56","issue":"4","first_page":"821","last_page":"827"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.014399999752640724,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/erythropoietin","display_name":"erythropoietin","score":1.0},{"id":"https://openalex.org/keywords/erythropoietin-receptor","display_name":"erythropoietin receptor","score":1.0},{"id":"https://openalex.org/keywords/spinal-cord-injury","display_name":"spinal cord injury","score":0.9980000257492065},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.8629999756813049},{"id":"https://openalex.org/keywords/glial-cells","display_name":"glial cells","score":0.7789999842643738},{"id":"https://openalex.org/keywords/vascular-endothelium","display_name":"vascular endothelium","score":0.9800000190734863},{"id":"https://openalex.org/keywords/ependymal-cells","display_name":"ependymal cells","score":0.8379999995231628},{"id":"https://openalex.org/keywords/neuronal-expression","display_name":"neuronal expression","score":0.5130000114440918},{"id":"https://openalex.org/keywords/central-nervous-system","display_name":"central nervous system","score":0.6159999966621399}],"concepts":[{"id":"https://openalex.org/C2778534260","wikidata":"https://www.wikidata.org/wiki/Q218706","display_name":"Erythropoietin","level":2,"score":0.9691798090934753},{"id":"https://openalex.org/C31102739","wikidata":"https://www.wikidata.org/wiki/Q14904899","display_name":"Erythropoietin receptor","level":3,"score":0.8525936603546143},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8414134979248047},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.6722959280014038},{"id":"https://openalex.org/C2778334475","wikidata":"https://www.wikidata.org/wiki/Q1415275","display_name":"Spinal cord injury","level":3,"score":0.6551162600517273},{"id":"https://openalex.org/C25498285","wikidata":"https://www.wikidata.org/wiki/Q1981368","display_name":"Neuroprotection","level":2,"score":0.601250410079956},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.5534263253211975},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.5060333609580994},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3596757650375366},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3498248755931854},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000783","descriptor_name":"Aneurysm","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004921","descriptor_name":"Erythropoietin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004921","descriptor_name":"Erythropoietin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013117","descriptor_name":"Spinal Cord Compression","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D013119","descriptor_name":"Spinal Cord Injuries","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D013119","descriptor_name":"Spinal Cord Injuries","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017467","descriptor_name":"Receptors, Erythropoietin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1227/01.neu.0000156493.00904.7e","doi":"https://doi.org/10.1227/01.neu.0000156493.00904.7e","is_oa":false,"landing_page_url":"https://doi.org/10.1227/01.neu.0000156493.00904.7e","pdf_url":null,"source":{"id":"https://openalex.org/S111727011","display_name":"Neurosurgery","issn_l":"0148-396X","issn":["0148-396X","1081-1281","1524-4040"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurosurgery","raw_type":"journal-article"},{"id":"pmid:15792521","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15792521","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurosurgery","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unipa.it:10447/24930","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10447/24930","pdf_url":null,"source":{"id":"https://openalex.org/S4306401065","display_name":"Nova Science Publishers (Nova Science Publishers, Inc.)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W43446693","https://openalex.org/W141799690","https://openalex.org/W1504583940","https://openalex.org/W1973178224","https://openalex.org/W1976869427","https://openalex.org/W1978726693","https://openalex.org/W1983735912","https://openalex.org/W1994149835","https://openalex.org/W1997031088","https://openalex.org/W2004707358","https://openalex.org/W2005002385","https://openalex.org/W2010550291","https://openalex.org/W2017702900","https://openalex.org/W2018039414","https://openalex.org/W2018909644","https://openalex.org/W2034987918","https://openalex.org/W2041098348","https://openalex.org/W2041939561","https://openalex.org/W2047950367","https://openalex.org/W2064048040","https://openalex.org/W2078022765","https://openalex.org/W2099867389","https://openalex.org/W2106589023","https://openalex.org/W2118234034","https://openalex.org/W2120231263","https://openalex.org/W2122965222","https://openalex.org/W2125806058","https://openalex.org/W2136703696","https://openalex.org/W2142463112","https://openalex.org/W2151480202","https://openalex.org/W2162264368","https://openalex.org/W2312614343","https://openalex.org/W2401117897","https://openalex.org/W2406656382","https://openalex.org/W2555626204","https://openalex.org/W3144580160","https://openalex.org/W6661017423"],"related_works":["https://openalex.org/W6946396596","https://openalex.org/W2376813858","https://openalex.org/W283095698","https://openalex.org/W3030875805","https://openalex.org/W2052926406","https://openalex.org/W2034987918","https://openalex.org/W2114690241","https://openalex.org/W7096271428","https://openalex.org/W2005738469","https://openalex.org/W2754724961"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Erythropoietin":[1],"(EPO)":[2],"is":[3,45,69,211],"a":[4,147,239],"pleiotropic":[5],"cytokine":[6],"originally":[7],"identified":[8],"for":[9],"its":[10,21],"role":[11],"in":[12,26,48,71,85,108,131,139,158,188,214,224,230],"erythropoiesis.":[13],"Recent":[14],"studies":[15],"have":[16],"demonstrated":[17],"that":[18,204],"EPO":[19,32,41,65,89,126,153,183,207,225,245],"and":[20,42,66,90,101,105,114,127,133,141,154,162,193,208,227],"receptor":[22],"(EPO-R)":[23],"are":[24],"expressed":[25,196],"the":[27,37,40,49,53,56,63,72,109,205,215,228,235],"central":[28,50],"nervous":[29,51,74,219],"system,":[30,52],"where":[31],"exerts":[33],"neuroprotective":[34],"functions.":[35],"Because":[36],"expression":[38,92,124,151],"of":[39,55,80,112,125,150,152,238],"EPO-R":[43,67,91,128,155,198,209,231],"network":[44,68],"poorly":[46],"investigated":[47],"aim":[54],"present":[57],"study":[58],"was":[59,87,93,129,156,185],"to":[60],"investigate":[61],"whether":[62],"resident":[64],"activated":[70],"injured":[73,113,145],"system.":[75],"METHODS:":[76],"A":[77],"well-standardized":[78],"model":[79],"compressive":[81],"spinal":[82,110,120],"cord":[83,111],"injury":[84],"rats":[86],"used.":[88],"determined":[94],"by":[95],"immunohistochemical":[96,123],"analysis":[97],"at":[98,102,165,171],"8":[99,166,172],"hours":[100,167],"2,":[103],"8,":[104],"14":[106],"days":[107],"noninjured":[115,119],"rats.":[116],"RESULTS:":[117],"In":[118,144],"cord,":[121],"weak":[122],"observed":[130,157],"neuronal":[132],"glial":[134,163,191],"cells":[135,164,192],"as":[136,138],"well":[137],"endothelial":[140],"ependymal":[142],"cells.":[143],"rats,":[146],"marked":[148],"increase":[149,229],"neurons,":[159,189],"vascular":[160,194],"endothelium,":[161],"after":[168,174,181,218],"injury,":[169,182],"peaking":[170],"days,":[173],"which":[175],"it":[176],"gradually":[177],"decreased.":[178],"Two":[179],"weeks":[180],"immunoreactivity":[184],"scarcely":[186],"detected":[187],"whereas":[190],"endothelium":[195],"strong":[197],"immunoreactivity.":[199],"CONCLUSION:":[200],"These":[201],"observations":[202],"suggest":[203],"local":[206],"system":[210],"markedly":[212],"engaged":[213],"early":[216],"stages":[217],"tissue":[220],"injury.":[221],"The":[222],"reduction":[223],"immunoexpression":[226],"staining":[232],"strongly":[233],"support":[234],"possible":[236],"usefulness":[237],"therapeutic":[240],"approach":[241],"based":[242],"on":[243],"exogenous":[244],"administration.":[246]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}