{"id":"https://openalex.org/W2017507208","doi":"https://doi.org/10.1001/jamapsychiatry.2014.1763","title":"Benzodiazepine Use in the United States","display_name":"Benzodiazepine Use in the United States","publication_year":2014,"publication_date":"2014-12-18","ids":{"openalex":"https://openalex.org/W2017507208","doi":"https://doi.org/10.1001/jamapsychiatry.2014.1763","mag":"2017507208","pmid":"https://pubmed.ncbi.nlm.nih.gov/25517224"},"language":"en","primary_location":{"id":"doi:10.1001/jamapsychiatry.2014.1763","doi":"https://doi.org/10.1001/jamapsychiatry.2014.1763","is_oa":false,"landing_page_url":"https://doi.org/10.1001/jamapsychiatry.2014.1763","pdf_url":null,"source":{"id":"https://openalex.org/S2495708506","display_name":"JAMA Psychiatry","issn_l":"2168-622X","issn":["2168-622X","2168-6238"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA Psychiatry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015272156","display_name":"Mark Olfson","orcid":"https://orcid.org/0000-0002-3958-5662","observed_orcids":["https://orcid.org/0000-0002-3958-5662"]},"institutions":[{"id":"https://openalex.org/I4388891851","display_name":"New York State Psychiatric Institute","ror":"https://ror.org/04aqjf708","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4388891851"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Olfson","raw_affiliation_strings":["Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York2New York State Psychiatric Institute, New York","New York State Psychiatric Institute, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York2New York State Psychiatric Institute, New York","institution_ids":["https://openalex.org/I4388891851","https://openalex.org/I78577930"]},{"raw_affiliation_string":"New York State Psychiatric Institute, New York","institution_ids":["https://openalex.org/I4388891851"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040819800","display_name":"Marissa D. King","orcid":"https://orcid.org/0009-0000-6590-3567","observed_orcids":["https://orcid.org/0009-0000-6590-3567"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marissa King","raw_affiliation_strings":["School of Management, Yale University, New Haven, Connecticut"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Management, Yale University, New Haven, Connecticut","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057621855","display_name":"Michael Schoenbaum","orcid":"https://orcid.org/0000-0002-7793-6734","observed_orcids":["https://orcid.org/0000-0002-7793-6734"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210091794","display_name":"Office of the Director","ror":"https://ror.org/00fj8a872","country_code":"US","type":"other","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210091794"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Schoenbaum","raw_affiliation_strings":["Office of the Director, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Office of the Director, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210091794","https://openalex.org/I4210158500"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":38.7203,"has_fulltext":false,"cited_by_count":809,"citation_normalized_percentile":{"value":0.99946121,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"72","issue":"2","first_page":"136","last_page":"136"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10496","display_name":"Pharmaceutical Practices and Patient Outcomes","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10496","display_name":"Pharmaceutical Practices and Patient Outcomes","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":0.013100000098347664,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/benzodiazepine-use","display_name":"benzodiazepine use","score":0.8759999871253967},{"id":"https://openalex.org/keywords/prescribing-patterns","display_name":"prescribing patterns","score":0.8610000014305115},{"id":"https://openalex.org/keywords/prevalence","display_name":"prevalence","score":0.6290000081062317},{"id":"https://openalex.org/keywords/age-differences","display_name":"age differences","score":0.8330000042915344},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7229999899864197},{"id":"https://openalex.org/keywords/long-term-benzodiazepine-use","display_name":"long-term benzodiazepine use","score":0.9559999704360962},{"id":"https://openalex.org/keywords/long-acting-benzodiazepines","display_name":"long-acting benzodiazepines","score":0.9350000023841858},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.8090000152587891},{"id":"https://openalex.org/keywords/psychiatrists","display_name":"psychiatrists","score":0.5230000019073486},{"id":"https://openalex.org/keywords/united-states-adults","display_name":"United States adults","score":0.6100000143051147},{"id":"https://openalex.org/keywords/benzodiazepine-withdrawal","display_name":"benzodiazepine withdrawal","score":0.46000000834465027},{"id":"https://openalex.org/keywords/benzodiazepine-dependence","display_name":"benzodiazepine dependence","score":0.6470000147819519}],"concepts":[{"id":"https://openalex.org/C2778173252","wikidata":"https://www.wikidata.org/wiki/Q83871","display_name":"Benzodiazepine","level":3,"score":0.8627445697784424},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.769683301448822},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6397520899772644},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5021255016326904},{"id":"https://openalex.org/C104863432","wikidata":"https://www.wikidata.org/wiki/Q614304","display_name":"Pharmacy","level":2,"score":0.49918198585510254},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.40350833535194397},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18838712573051453},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.1025753915309906},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.10020563006401062},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.09477230906486511},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001569","descriptor_name":"Benzodiazepines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D001569","descriptor_name":"Benzodiazepines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011307","descriptor_name":"Drug Prescriptions","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1001/jamapsychiatry.2014.1763","doi":"https://doi.org/10.1001/jamapsychiatry.2014.1763","is_oa":false,"landing_page_url":"https://doi.org/10.1001/jamapsychiatry.2014.1763","pdf_url":null,"source":{"id":"https://openalex.org/S2495708506","display_name":"JAMA Psychiatry","issn_l":"2168-622X","issn":["2168-622X","2168-6238"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA Psychiatry","raw_type":"journal-article"},{"id":"pmid:25517224","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25517224","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA psychiatry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1066674785","display_name":null,"funder_award_id":"U19HSO2112","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"}],"funders":[{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":74,"referenced_works":["https://openalex.org/W101037913","https://openalex.org/W139038528","https://openalex.org/W1479778303","https://openalex.org/W1480559618","https://openalex.org/W1503594705","https://openalex.org/W1504483181","https://openalex.org/W1538467883","https://openalex.org/W1585855347","https://openalex.org/W1819208983","https://openalex.org/W1964195870","https://openalex.org/W1972782221","https://openalex.org/W1974600523","https://openalex.org/W1976211711","https://openalex.org/W1976653843","https://openalex.org/W1988605938","https://openalex.org/W1991958065","https://openalex.org/W1995732384","https://openalex.org/W1998935547","https://openalex.org/W1999146743","https://openalex.org/W2001480478","https://openalex.org/W2002669039","https://openalex.org/W2012819177","https://openalex.org/W2014255786","https://openalex.org/W2015667356","https://openalex.org/W2015725434","https://openalex.org/W2017919829","https://openalex.org/W2023001725","https://openalex.org/W2024111201","https://openalex.org/W2024784435","https://openalex.org/W2029853434","https://openalex.org/W2031479780","https://openalex.org/W2039329553","https://openalex.org/W2043524145","https://openalex.org/W2044419673","https://openalex.org/W2048458454","https://openalex.org/W2053311281","https://openalex.org/W2058854656","https://openalex.org/W2060168054","https://openalex.org/W2063190694","https://openalex.org/W2064623716","https://openalex.org/W2064690703","https://openalex.org/W2074151298","https://openalex.org/W2078192945","https://openalex.org/W2079238909","https://openalex.org/W2082637065","https://openalex.org/W2084110973","https://openalex.org/W2087385933","https://openalex.org/W2089366409","https://openalex.org/W2094113973","https://openalex.org/W2097536190","https://openalex.org/W2104265001","https://openalex.org/W2106413518","https://openalex.org/W2108963305","https://openalex.org/W2111180320","https://openalex.org/W2113021977","https://openalex.org/W2123777323","https://openalex.org/W2132305736","https://openalex.org/W2132954437","https://openalex.org/W2133040389","https://openalex.org/W2139770333","https://openalex.org/W2146393320","https://openalex.org/W2151852296","https://openalex.org/W2153607529","https://openalex.org/W2158086946","https://openalex.org/W2158087005","https://openalex.org/W2158328803","https://openalex.org/W2159480936","https://openalex.org/W2163313694","https://openalex.org/W2168539205","https://openalex.org/W2169363431","https://openalex.org/W2170269536","https://openalex.org/W2171720080","https://openalex.org/W2257575319","https://openalex.org/W2419345016"],"related_works":["https://openalex.org/W2063528821","https://openalex.org/W151694265","https://openalex.org/W2081536163","https://openalex.org/W2338961894","https://openalex.org/W2597155422","https://openalex.org/W2001756062","https://openalex.org/W7220838323","https://openalex.org/W4402218659","https://openalex.org/W4254644224","https://openalex.org/W2555861908"],"abstract_inverted_index":{"IMPORTANCE:":[0],"Although":[1],"concern":[2],"exists":[3],"regarding":[4],"the":[5,26,36,61,80,90,108,130,221],"rate":[6],"of":[7,22,45,55,75,99,140,155,202,248,295],"benzodiazepine":[8,23,32,56,105,137,145,203,226,251,254,266,273,287,297],"use,":[9,138,267],"especially":[10,268],"long-term":[11,134,265,272,296],"use":[12,24,190,204,274,288,298],"by":[13,111],"older":[14,270,300],"adults,":[15],"little":[16],"information":[17],"is":[18],"available":[19],"concerning":[20,261],"patterns":[21,34],"in":[25,35,79,196,269,277,299],"United":[27,37,81],"States.":[28,82],"OBJECTIVE:":[29],"To":[30],"describe":[31],"prescription":[33,139,227],"States":[38],"focusing":[39],"on":[40],"patient":[41],"age":[42,114,172,211,233,244,279],"and":[43,113,122,125,144],"duration":[44],"use.":[46,255],"DESIGN,":[47],"SETTING,":[48],"AND":[49,95,257],"PARTICIPANTS:":[50],"A":[51],"retrospective":[52],"descriptive":[53],"analysis":[54],"prescriptions":[57,106,146],"was":[58,191,206],"performed":[59],"with":[60,133,171,210,232,264],"2008":[62],"LifeLink":[63],"LRx":[64],"Longitudinal":[65],"Prescription":[66],"database":[67],"(IMS":[68],"Health":[69],"Inc),":[70],"which":[71],"includes":[72],"approximately":[73,153],"60%":[74],"all":[76,243],"retail":[77],"pharmacies":[78],"Denominators":[83],"were":[84],"adjusted":[85],"to":[86,89,160,177,181,185,216,238,292],"generalize":[87],"estimates":[88],"US":[91,156],"population.":[92],"MAIN":[93],"OUTCOMES":[94],"MEASURES:":[96],"The":[97,165,200],"percentage":[98,166],"adults":[100,157],"filling":[101],"1":[102],"or":[103],"more":[104],"during":[107],"study":[109],"year":[110],"sex":[112],"group":[115],"(18-35":[116,175,214,236],"years,":[117,119,121],"36-50":[118],"51-64":[120],"65-80":[123],"years)":[124,176,180,184,215,237],"among":[126],"individuals":[127,249],"receiving":[128,250],"benzodiazepines,":[129],"corresponding":[131],"percentages":[132],"(\u2265120":[135],"days)":[136],"a":[141,148,225,229],"long-acting":[142,253],"benzodiazepine,":[143],"from":[147,173,212,228,234],"psychiatrist.":[149],"RESULTS:":[150],"In":[151,242],"2008,":[152],"5.2%":[154],"aged":[158],"18":[159],"80":[161],"years":[162],"used":[163,168],"benzodiazepines.":[164],"who":[167],"benzodiazepines":[169],"increased":[170,209],"2.6%":[174],"5.4%":[178],"(36-50":[179],"7.4%":[182],"(51-64":[183],"8.7%":[186],"(65-80":[187,218,240],"years).":[188,241],"Benzodiazepine":[189],"nearly":[192],"twice":[193],"as":[194,198],"prevalent":[195],"women":[197],"men.":[199],"proportion":[201,222],"that":[205,223],"long":[207],"term":[208],"14.7%":[213],"31.4%":[217],"years),":[219],"while":[220],"received":[224],"psychiatrist":[230],"decreased":[231],"15.0%":[235],"5.7%":[239],"groups,":[245],"roughly":[246],"one-quarter":[247],"involved":[252],"CONCLUSIONS":[256],"RELEVANCE:":[258],"Despite":[259],"cautions":[260],"risks":[262],"associated":[263],"patients,":[271],"remains":[275],"common":[276],"this":[278],"group.":[280],"More":[281],"vigorous":[282],"clinical":[283],"interventions":[284],"supporting":[285],"judicious":[286],"may":[289],"be":[290],"needed":[291],"decrease":[293],"rates":[294],"adults.":[301]},"counts_by_year":[{"year":2026,"cited_by_count":54},{"year":2025,"cited_by_count":52},{"year":2024,"cited_by_count":75},{"year":2023,"cited_by_count":59},{"year":2022,"cited_by_count":71},{"year":2021,"cited_by_count":72},{"year":2020,"cited_by_count":86},{"year":2019,"cited_by_count":89},{"year":2018,"cited_by_count":100},{"year":2017,"cited_by_count":56},{"year":2016,"cited_by_count":53},{"year":2015,"cited_by_count":40},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}