{"id":"https://openalex.org/W2017388332","doi":"https://doi.org/10.1097/mlg.0b013e31802dc5bc","title":"Effects of Fibrin Glue on Nasal Septal Tissues","display_name":"Effects of Fibrin Glue on Nasal Septal Tissues","publication_year":2007,"publication_date":"2007-03-01","ids":{"openalex":"https://openalex.org/W2017388332","doi":"https://doi.org/10.1097/mlg.0b013e31802dc5bc","mag":"2017388332","pmid":"https://pubmed.ncbi.nlm.nih.gov/17334310"},"language":"en","primary_location":{"id":"doi:10.1097/mlg.0b013e31802dc5bc","doi":"https://doi.org/10.1097/mlg.0b013e31802dc5bc","is_oa":false,"landing_page_url":"https://doi.org/10.1097/mlg.0b013e31802dc5bc","pdf_url":null,"source":{"id":"https://openalex.org/S86387881","display_name":"The Laryngoscope","issn_l":"0023-852X","issn":["0023-852X","1091-756X","1531-4995"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Laryngoscope","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2017388332"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090371841","display_name":"Alper Nabi Erkan","orcid":"https://orcid.org/0000-0001-7138-1400","observed_orcids":["https://orcid.org/0000-0001-7138-1400"]},"institutions":[{"id":"https://openalex.org/I188740104","display_name":"Ba\u015fkent University","ror":"https://ror.org/02v9bqx10","country_code":"TR","type":"education","lineage":["https://openalex.org/I188740104"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Alper Nabi Erkan","raw_affiliation_strings":["Department of Otorhinolaryngology, Baskent University Faculty of Medicine, Ankara, Turkey. alpernabierkan@yahoo.com","Department of Otorhinolaryngology; Baskent University Faculty of Medicine; Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology, Baskent University Faculty of Medicine, Ankara, Turkey. alpernabierkan@yahoo.com","institution_ids":["https://openalex.org/I188740104"]},{"raw_affiliation_string":"Department of Otorhinolaryngology; Baskent University Faculty of Medicine; Ankara, Turkey","institution_ids":["https://openalex.org/I188740104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104061242","display_name":"\u00d6zcan \u00c7akmak","orcid":"https://orcid.org/0009-0008-7804-5002","observed_orcids":["https://orcid.org/0009-0008-7804-5002"]},"institutions":[{"id":"https://openalex.org/I188740104","display_name":"Ba\u015fkent University","ror":"https://ror.org/02v9bqx10","country_code":"TR","type":"education","lineage":["https://openalex.org/I188740104"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ozcan Cakmak","raw_affiliation_strings":["Departments of Otorhinolaryngology, Baskent University Faculty of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Otorhinolaryngology, Baskent University Faculty of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I188740104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004582523","display_name":"N. Emrah Ko\u00e7er","orcid":"https://orcid.org/0000-0002-5943-9283","observed_orcids":["https://orcid.org/0000-0002-5943-9283","https://orcid.org/0000-0003-3636-8109"]},"institutions":[{"id":"https://openalex.org/I188740104","display_name":"Ba\u015fkent University","ror":"https://ror.org/02v9bqx10","country_code":"TR","type":"education","lineage":["https://openalex.org/I188740104"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Nazm Emrah Kocer","raw_affiliation_strings":["Departments of Pathology, Baskent University Faculty of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pathology, Baskent University Faculty of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I188740104"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111664116","display_name":"Ismail Ylmaz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188740104","display_name":"Ba\u015fkent University","ror":"https://ror.org/02v9bqx10","country_code":"TR","type":"education","lineage":["https://openalex.org/I188740104"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ismail Ylmaz","raw_affiliation_strings":["Departments of Otorhinolaryngology, Baskent University Faculty of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Otorhinolaryngology, Baskent University Faculty of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I188740104"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5090371841"],"corresponding_institution_ids":["https://openalex.org/I188740104"],"apc_list":{"value":4840,"currency":"USD","value_usd":4840},"apc_paid":null,"fwci":1.3968,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.80054675,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"117","issue":"3","first_page":"491","last_page":"496"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11812","display_name":"Nasal Surgery and Airway Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11812","display_name":"Nasal Surgery and Airway Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12548","display_name":"Hemostasis and retained surgical items","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10984","display_name":"Sinusitis and nasal conditions","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fibrin-glue","display_name":"fibrin glue","score":0.9929999709129333},{"id":"https://openalex.org/keywords/nasal-septum","display_name":"nasal septum","score":0.8100000023841858},{"id":"https://openalex.org/keywords/septoplasty","display_name":"septoplasty","score":0.996999979019165},{"id":"https://openalex.org/keywords/mucoperichondrial-flap","display_name":"mucoperichondrial flap","score":0.921999990940094},{"id":"https://openalex.org/keywords/septal-cartilage","display_name":"septal cartilage","score":0.796999990940094},{"id":"https://openalex.org/keywords/perichondrium","display_name":"perichondrium","score":0.8489999771118164},{"id":"https://openalex.org/keywords/mucosal-inflammation","display_name":"mucosal inflammation","score":0.8510000109672546},{"id":"https://openalex.org/keywords/cilia-loss","display_name":"cilia loss","score":0.75},{"id":"https://openalex.org/keywords/goblet-cells","display_name":"goblet cells","score":0.968999981880188},{"id":"https://openalex.org/keywords/fibrosis","display_name":"fibrosis","score":0.9259999990463257},{"id":"https://openalex.org/keywords/cartilage-destruction","display_name":"cartilage destruction","score":0.6769999861717224},{"id":"https://openalex.org/keywords/mucosal-thickness","display_name":"mucosal thickness","score":0.722000002861023},{"id":"https://openalex.org/keywords/rabbit-model","display_name":"rabbit model","score":0.8090000152587891}],"concepts":[{"id":"https://openalex.org/C2781472170","wikidata":"https://www.wikidata.org/wiki/Q1410780","display_name":"Fibrin glue","level":2,"score":0.8721752166748047},{"id":"https://openalex.org/C25515809","wikidata":"https://www.wikidata.org/wiki/Q663949","display_name":"Perichondrium","level":3,"score":0.7935086488723755},{"id":"https://openalex.org/C2777733662","wikidata":"https://www.wikidata.org/wiki/Q1973252","display_name":"Septoplasty","level":3,"score":0.7899045944213867},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.7338813543319702},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6403617858886719},{"id":"https://openalex.org/C2777917003","wikidata":"https://www.wikidata.org/wiki/Q500634","display_name":"Nasal septum","level":3,"score":0.5580774545669556},{"id":"https://openalex.org/C54173615","wikidata":"https://www.wikidata.org/wiki/Q27205","display_name":"Fibrin","level":2,"score":0.5475585460662842},{"id":"https://openalex.org/C59377437","wikidata":"https://www.wikidata.org/wiki/Q515471","display_name":"Mucous membrane of nose","level":2,"score":0.4290086030960083},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.4271390736103058},{"id":"https://openalex.org/C2910882873","wikidata":"https://www.wikidata.org/wiki/Q1410780","display_name":"Fibrin Tissue Adhesive","level":3,"score":0.4145911931991577},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4102257490158081},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.38279104232788086},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3743664622306824},{"id":"https://openalex.org/C2778311950","wikidata":"https://www.wikidata.org/wiki/Q7363","display_name":"Nose","level":2,"score":0.29855769872665405},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.06986621022224426}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009297","descriptor_name":"Nasal Mucosa","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009297","descriptor_name":"Nasal Mucosa","qualifier_ui":"Q000637","qualifier_name":"transplantation","is_major_topic":true},{"descriptor_ui":"D009300","descriptor_name":"Nasal Septum","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009300","descriptor_name":"Nasal Septum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009300","descriptor_name":"Nasal Septum","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012220","descriptor_name":"Rhinitis","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D012220","descriptor_name":"Rhinitis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012225","descriptor_name":"Rhinoplasty","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D013524","descriptor_name":"Surgical Flaps","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014014","descriptor_name":"Tissue Adhesives","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D015718","descriptor_name":"Fibrin Tissue Adhesive","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/mlg.0b013e31802dc5bc","doi":"https://doi.org/10.1097/mlg.0b013e31802dc5bc","is_oa":false,"landing_page_url":"https://doi.org/10.1097/mlg.0b013e31802dc5bc","pdf_url":null,"source":{"id":"https://openalex.org/S86387881","display_name":"The Laryngoscope","issn_l":"0023-852X","issn":["0023-852X","1091-756X","1531-4995"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Laryngoscope","raw_type":"journal-article"},{"id":"pmid:17334310","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17334310","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Laryngoscope","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W150464595","https://openalex.org/W2005040886","https://openalex.org/W2005957280","https://openalex.org/W2013211163","https://openalex.org/W2021138919","https://openalex.org/W2026133365","https://openalex.org/W2031016315","https://openalex.org/W2038572664","https://openalex.org/W2039942360","https://openalex.org/W2064179186","https://openalex.org/W2077443685","https://openalex.org/W2089383960","https://openalex.org/W2405304854","https://openalex.org/W2408034794","https://openalex.org/W2603289006"],"related_works":["https://openalex.org/W2724556122","https://openalex.org/W3183300524","https://openalex.org/W3128741925","https://openalex.org/W7171538398","https://openalex.org/W160218245","https://openalex.org/W1973944738","https://openalex.org/W2064179186","https://openalex.org/W2371410934","https://openalex.org/W4298210671","https://openalex.org/W4323237175"],"abstract_inverted_index":{"OBJECTIVES:":[0],"To":[1],"investigate":[2,65],"the":[3,32,75,82,90,94,109,129,166,182,185,189,238],"changes":[4],"in":[5,31,61,156,228,244,248],"adult":[6,25],"rabbit":[7],"nasal":[8,111,245],"septal":[9,95,246],"tissues":[10],"after":[11,105],"application":[12],"of":[13,70,81,158,160,163,170,173,184,188,193,241],"fibrin":[14,71,84,206,242],"glue":[15,85,207,243],"during":[16],"septoplasty.":[17,106],"STUDY":[18],"DESIGN:":[19],"Preclinical":[20],"animal":[21],"study.":[22,33],"METHODS:":[23],"Nineteen":[24],"albino":[26],"Vienna":[27],"rabbits":[28,60],"were":[29,35,98,126,196],"included":[30],"Rabbits":[34,97],"randomly":[36],"divided":[37,54],"into":[38,55],"study":[39,50],"(n":[40,46],"=":[41,47],"14)":[42],"and":[43,67,102,123,132,144,168,191,220,223],"control":[44,130],"groups":[45,155],"5).":[48],"The":[49],"group":[51,63,131],"was":[52,86,137,152,175],"subsequently":[53],"two":[56],"subgroups":[57],"with":[58,128,133],"seven":[59],"each":[62,134],"to":[64,88,236],"short-":[66],"long-term":[68,124],"effects":[69],"glue.":[72],"After":[73],"raising":[74],"mucoperichondrial":[76,91],"flap":[77,92],"on":[78],"one":[79],"side":[80],"septum,":[83],"used":[87],"fix":[89],"over":[93],"cartilage.":[96],"killed":[99],"3":[100],"weeks":[101,104],"6":[103],"Samples":[107],"from":[108],"excised":[110],"septa":[112],"underwent":[113],"routine":[114],"tissue":[115],"procedure":[116],"for":[117],"histopathologic":[118],"investigation.":[119],"RESULTS:":[120],"Both":[121],"short-term":[122],"results":[125,203],"compared":[127],"other.":[135],"There":[136],"a":[138],"significant":[139,150,197],"difference":[140,151],"regarding":[141],"mucosal":[142,212,215],"inflammation":[143],"cartilaginous":[145,221],"damage":[146],"between":[147,154,178,199],"groups.":[148,179,200],"A":[149],"found":[153],"terms":[157],"loss":[159,162,227],"cilia,":[161],"goblet":[164],"cells,":[165],"presence":[167],"degree":[169],"fibrosis.":[171],"Loss":[172],"cartilage":[174,226],"significantly":[176],"different":[177],"In":[180],"comparing":[181],"thickness":[183,187,192,219],"mucosa,":[186],"perichondrium,":[190],"cartilage,":[194],"there":[195],"differences":[198],"CONCLUSION:":[201],"Our":[202],"demonstrate":[204],"that":[205],"causes":[208,224],"distinctive":[209],"inflammation,":[210],"creates":[211],"damage,":[213],"increases":[214],"thickness,":[216,222],"decreases":[217],"perichondrial":[218],"segmental":[225],"rabbits.":[229],"Further":[230],"comparative":[231],"clinical":[232,239],"investigations":[233],"are":[234],"required":[235],"assess":[237],"efficacy":[240],"surgery":[247],"humans.":[249]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}