{"id":"https://openalex.org/W2017336455","doi":"https://doi.org/10.1007/s10555-012-9370-z","title":"Plasticity of disseminating cancer cells in patients with epithelial malignancies","display_name":"Plasticity of disseminating cancer cells in patients with epithelial malignancies","publication_year":2012,"publication_date":"2012-06-25","ids":{"openalex":"https://openalex.org/W2017336455","doi":"https://doi.org/10.1007/s10555-012-9370-z","mag":"2017336455","pmid":"https://pubmed.ncbi.nlm.nih.gov/22733306"},"language":"en","primary_location":{"id":"doi:10.1007/s10555-012-9370-z","doi":"https://doi.org/10.1007/s10555-012-9370-z","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10555-012-9370-z","pdf_url":null,"source":{"id":"https://openalex.org/S114927911","display_name":"Cancer and Metastasis Reviews","issn_l":"0167-7659","issn":["0167-7659","1573-7233"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer and Metastasis Reviews","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2017336455"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038334067","display_name":"Natalia Bednarz\u2010Knoll","orcid":"https://orcid.org/0000-0001-9506-942X","observed_orcids":["https://orcid.org/0000-0001-9506-942X"]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"id":"https://openalex.org/I4210125929","display_name":"University Cancer Center Hamburg","ror":"https://ror.org/02b48z609","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711","https://openalex.org/I4210125929"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Natalia Bednarz-Knoll","raw_affiliation_strings":["Department of Tumour Biology, Center of Experimental Medicine, University Cancer Center Hamburg, University Medical Centre Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany. nataliabednarz@wp.pl","Department of Tumour Biology, Center of Experimental Medicine, University Cancer Center Hamburg, University Medical Centre Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Tumour Biology, Center of Experimental Medicine, University Cancer Center Hamburg, University Medical Centre Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany. nataliabednarz@wp.pl","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711","https://openalex.org/I4210125929"]},{"raw_affiliation_string":"Department of Tumour Biology, Center of Experimental Medicine, University Cancer Center Hamburg, University Medical Centre Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711","https://openalex.org/I4210125929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043582421","display_name":"Catherine Alix\u2010Panabi\u00e8res","orcid":"https://orcid.org/0000-0002-6401-2903","observed_orcids":["https://orcid.org/0000-0002-6401-2903"]},"institutions":[{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4210093292","display_name":"Centre Hospitalier Universitaire de Montpellier","ror":"https://ror.org/00mthsf17","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210093292"]},{"id":"https://openalex.org/I4210143740","display_name":"H\u00f4pital Saint Eloi","ror":"https://ror.org/04pwyfk22","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210093292","https://openalex.org/I4210143740"]},{"id":"https://openalex.org/I4210147545","display_name":"H\u00f4pital Arnaud de Villeneuve","ror":"https://ror.org/04m6sq715","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210093292","https://openalex.org/I4210147545"]},{"id":"https://openalex.org/I4387153574","display_name":"Universit\u00e9 Montpellier 1","ror":"https://ror.org/0227fbx80","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307","https://openalex.org/I4387153574"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Catherine Alix-Panabi\u00e8res","raw_affiliation_strings":["Biostatistics and Public Health, University Institute of Clinical Research UM1-EA2415-Epidemiology, Montpellier, France","Institute of Research in Biotherapy, Laboratory of Rare Human Circulating Cells, University Medical Centre, University Montpellier 1, Saint-Eloi Hospital, Montpellier, France","Laboratory of Cell and Hormonal Biology, Arnaud de Villeneuve Hospital, University Medical Centre, Montpellier, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biostatistics and Public Health, University Institute of Clinical Research UM1-EA2415-Epidemiology, Montpellier, France","institution_ids":[]},{"raw_affiliation_string":"Institute of Research in Biotherapy, Laboratory of Rare Human Circulating Cells, University Medical Centre, University Montpellier 1, Saint-Eloi Hospital, Montpellier, France","institution_ids":["https://openalex.org/I19894307","https://openalex.org/I4210143740","https://openalex.org/I4387153574"]},{"raw_affiliation_string":"Laboratory of Cell and Hormonal Biology, Arnaud de Villeneuve Hospital, University Medical Centre, Montpellier, France","institution_ids":["https://openalex.org/I4210093292","https://openalex.org/I4210147545"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048105827","display_name":"Klaus Pantel","orcid":"https://orcid.org/0000-0001-5736-2772","observed_orcids":["https://orcid.org/0000-0001-5736-2772"]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"id":"https://openalex.org/I4210125929","display_name":"University Cancer Center Hamburg","ror":"https://ror.org/02b48z609","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711","https://openalex.org/I4210125929"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Klaus Pantel","raw_affiliation_strings":["Department of Tumour Biology, Center of Experimental Medicine, University Cancer Center Hamburg, University Medical Centre Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Tumour Biology, Center of Experimental Medicine, University Cancer Center Hamburg, University Medical Centre Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711","https://openalex.org/I4210125929"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5048105827"],"corresponding_institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711","https://openalex.org/I4210125929"],"apc_list":{"value":3790,"currency":"USD","value_usd":3790},"apc_paid":null,"fwci":3.0905,"has_fulltext":false,"cited_by_count":222,"citation_normalized_percentile":{"value":0.94644809,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"31","issue":"3-4","first_page":"673","last_page":"687"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13437","display_name":"Mechanisms of cancer metastasis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epithelial-mesenchymal-transition","display_name":"epithelial-mesenchymal transition","score":0.9350000023841858},{"id":"https://openalex.org/keywords/mesenchymal-epithelial-transition","display_name":"mesenchymal-epithelial transition","score":0.9990000128746033},{"id":"https://openalex.org/keywords/circulating-tumor-cells","display_name":"circulating tumor cells","score":0.9940000176429749},{"id":"https://openalex.org/keywords/tumor-plasticity","display_name":"tumor plasticity","score":0.6100000143051147},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.7889999747276306},{"id":"https://openalex.org/keywords/epithelial-malignancies","display_name":"epithelial malignancies","score":0.8650000095367432},{"id":"https://openalex.org/keywords/tumour-dissemination","display_name":"tumour dissemination","score":0.7789999842643738},{"id":"https://openalex.org/keywords/emt-markers","display_name":"EMT markers","score":0.6060000061988831}],"concepts":[{"id":"https://openalex.org/C76419328","wikidata":"https://www.wikidata.org/wiki/Q74419","display_name":"Epithelial\u2013mesenchymal transition","level":4,"score":0.7473180294036865},{"id":"https://openalex.org/C61238886","wikidata":"https://www.wikidata.org/wiki/Q5121689","display_name":"Circulating tumor cell","level":4,"score":0.7265673279762268},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.7210569977760315},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5832504034042358},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5472384095191956},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.5400079488754272},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5119863152503967},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.46283912658691406},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.4241657853126526},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.33962225914001465},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32096052169799805},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0786060094833374},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06264320015907288},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009360","descriptor_name":"Neoplastic Cells, Circulating","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009375","descriptor_name":"Neoplasms, Glandular and Epithelial","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058750","descriptor_name":"Epithelial-Mesenchymal Transition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D061206","descriptor_name":"Neoplasm Micrometastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10555-012-9370-z","doi":"https://doi.org/10.1007/s10555-012-9370-z","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10555-012-9370-z","pdf_url":null,"source":{"id":"https://openalex.org/S114927911","display_name":"Cancer and Metastasis Reviews","issn_l":"0167-7659","issn":["0167-7659","1573-7233"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer and Metastasis Reviews","raw_type":"journal-article"},{"id":"pmid:22733306","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22733306","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer metastasis reviews","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321114","display_name":"Bundesministerium f\u00fcr Bildung und Forschung","ror":"https://ror.org/04pz7b180"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":151,"referenced_works":["https://openalex.org/W1486351321","https://openalex.org/W1487373628","https://openalex.org/W1532716088","https://openalex.org/W1536326448","https://openalex.org/W1558034062","https://openalex.org/W1560758904","https://openalex.org/W1562355542","https://openalex.org/W1565417674","https://openalex.org/W1571158533","https://openalex.org/W1605655296","https://openalex.org/W1964008117","https://openalex.org/W1964060051","https://openalex.org/W1964081206","https://openalex.org/W1965568527","https://openalex.org/W1965812184","https://openalex.org/W1967625972","https://openalex.org/W1971180788","https://openalex.org/W1971707325","https://openalex.org/W1971849102","https://openalex.org/W1976015720","https://openalex.org/W1976736011","https://openalex.org/W1978301900","https://openalex.org/W1980299983","https://openalex.org/W1980901401","https://openalex.org/W1994220056","https://openalex.org/W1995097523","https://openalex.org/W1996118868","https://openalex.org/W1996660594","https://openalex.org/W2000571591","https://openalex.org/W2003638511","https://openalex.org/W2007897263","https://openalex.org/W2010079251","https://openalex.org/W2010854338","https://openalex.org/W2011666308","https://openalex.org/W2011845357","https://openalex.org/W2012247886","https://openalex.org/W2014119944","https://openalex.org/W2014691022","https://openalex.org/W2015652631","https://openalex.org/W2016121055","https://openalex.org/W2016356101","https://openalex.org/W2019214567","https://openalex.org/W2021677985","https://openalex.org/W2022616393","https://openalex.org/W2025647419","https://openalex.org/W2026591084","https://openalex.org/W2026759417","https://openalex.org/W2028672331","https://openalex.org/W2030753263","https://openalex.org/W2031709263","https://openalex.org/W2031735145","https://openalex.org/W2036447097","https://openalex.org/W2036752418","https://openalex.org/W2037607269","https://openalex.org/W2039957063","https://openalex.org/W2041353834","https://openalex.org/W2042198997","https://openalex.org/W2042349463","https://openalex.org/W2042969009","https://openalex.org/W2044702632","https://openalex.org/W2050692546","https://openalex.org/W2051227781","https://openalex.org/W2052421497","https://openalex.org/W2053059159","https://openalex.org/W2053908396","https://openalex.org/W2055330058","https://openalex.org/W2057142830","https://openalex.org/W2058395421","https://openalex.org/W2058935670","https://openalex.org/W2059024717","https://openalex.org/W2062187838","https://openalex.org/W2062265555","https://openalex.org/W2063140987","https://openalex.org/W2066518356","https://openalex.org/W2070291618","https://openalex.org/W2071355305","https://openalex.org/W2076804454","https://openalex.org/W2077697695","https://openalex.org/W2078370392","https://openalex.org/W2078904004","https://openalex.org/W2080264320","https://openalex.org/W2082055110","https://openalex.org/W2082155007","https://openalex.org/W2083267106","https://openalex.org/W2083942517","https://openalex.org/W2089370460","https://openalex.org/W2093472132","https://openalex.org/W2093977796","https://openalex.org/W2094337993","https://openalex.org/W2094850025","https://openalex.org/W2095911112","https://openalex.org/W2096636873","https://openalex.org/W2098006347","https://openalex.org/W2098143043","https://openalex.org/W2098585582","https://openalex.org/W2100251610","https://openalex.org/W2101500128","https://openalex.org/W2102198783","https://openalex.org/W2103736766","https://openalex.org/W2105019540","https://openalex.org/W2105396692","https://openalex.org/W2105739438","https://openalex.org/W2106181914","https://openalex.org/W2107930817","https://openalex.org/W2108296770","https://openalex.org/W2109696536","https://openalex.org/W2109974873","https://openalex.org/W2112680319","https://openalex.org/W2117098158","https://openalex.org/W2117398240","https://openalex.org/W2117692326","https://openalex.org/W2118610654","https://openalex.org/W2119299101","https://openalex.org/W2119584041","https://openalex.org/W2120422541","https://openalex.org/W2125051097","https://openalex.org/W2126236874","https://openalex.org/W2134203671","https://openalex.org/W2134811967","https://openalex.org/W2138885372","https://openalex.org/W2139465853","https://openalex.org/W2140551998","https://openalex.org/W2142114070","https://openalex.org/W2143468862","https://openalex.org/W2145795890","https://openalex.org/W2146654096","https://openalex.org/W2148874508","https://openalex.org/W2148998801","https://openalex.org/W2149271063","https://openalex.org/W2151029537","https://openalex.org/W2152393981","https://openalex.org/W2152425783","https://openalex.org/W2154589460","https://openalex.org/W2155008430","https://openalex.org/W2155892126","https://openalex.org/W2157214333","https://openalex.org/W2158230237","https://openalex.org/W2161862739","https://openalex.org/W2162502060","https://openalex.org/W2163113687","https://openalex.org/W2164618834","https://openalex.org/W2164916420","https://openalex.org/W2166428176","https://openalex.org/W2167664841","https://openalex.org/W2170157144","https://openalex.org/W2171298396","https://openalex.org/W2172225180","https://openalex.org/W2174449508","https://openalex.org/W2764474601","https://openalex.org/W4200531859","https://openalex.org/W4211225392"],"related_works":["https://openalex.org/W2979047447","https://openalex.org/W2618403463","https://openalex.org/W2518042319","https://openalex.org/W2561337944","https://openalex.org/W2020732208","https://openalex.org/W2337902560","https://openalex.org/W1560758904","https://openalex.org/W4308507783","https://openalex.org/W3140376088","https://openalex.org/W2082239705"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":15},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":29},{"year":2016,"cited_by_count":30},{"year":2015,"cited_by_count":26},{"year":2014,"cited_by_count":30},{"year":2013,"cited_by_count":24},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}
