{"id":"https://openalex.org/W2017320443","doi":"https://doi.org/10.1097/00003246-200104000-00034","title":"Effects of prophylactic fenoldopam infusion on renal blood flow and renal tubular function during acute hypovolemia in anesthetized dogs","display_name":"Effects of prophylactic fenoldopam infusion on renal blood flow and renal tubular function during acute hypovolemia in anesthetized dogs","publication_year":2001,"publication_date":"2001-04-01","ids":{"openalex":"https://openalex.org/W2017320443","doi":"https://doi.org/10.1097/00003246-200104000-00034","mag":"2017320443","pmid":"https://pubmed.ncbi.nlm.nih.gov/11373482"},"language":"en","primary_location":{"id":"doi:10.1097/00003246-200104000-00034","doi":"https://doi.org/10.1097/00003246-200104000-00034","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00003246-200104000-00034","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076511099","display_name":"M. Halpenny","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27577105","display_name":"University College Cork","ror":"https://ror.org/03265fv13","country_code":"IE","type":"education","lineage":["https://openalex.org/I27577105"]},{"id":"https://openalex.org/I4210100707","display_name":"Mercy University Hospital","ror":"https://ror.org/017q2rt66","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210100707"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Michele Halpenny","raw_affiliation_strings":["Department of Anesthesia and Intensive Care Medicine, Mercy Hospital and University College Cork, Wilton, Cork, Ireland","Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesia and Intensive Care Medicine, Mercy Hospital and University College Cork, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I27577105","https://openalex.org/I4210100707"]},{"raw_affiliation_string":"Ireland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061185644","display_name":"Farouk Markos","orcid":"https://orcid.org/0000-0003-0158-678X","observed_orcids":["https://orcid.org/0000-0003-0158-678X"]},"institutions":[{"id":"https://openalex.org/I27577105","display_name":"University College Cork","ror":"https://ror.org/03265fv13","country_code":"IE","type":"education","lineage":["https://openalex.org/I27577105"]},{"id":"https://openalex.org/I2802396013","display_name":"Cork University Hospital","ror":"https://ror.org/04q107642","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2802396013"]},{"id":"https://openalex.org/I4210100707","display_name":"Mercy University Hospital","ror":"https://ror.org/017q2rt66","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210100707"]},{"id":"https://openalex.org/I4210154619","display_name":"St. James's Hospital","ror":"https://ror.org/04c6bry31","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210154619"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Farouk Markos","raw_affiliation_strings":["From the Department of Anesthesia and Intensive Care Medicine (Dr. Halpenny), Mercy Hospital and University College Cork, Wilton, Cork, Ireland","and the Department of Pathology (Dr. Gaffney), St James\u2019s Hospital, Dublin, Ireland","the Department of Biochemistry (Dr. Duggan), Cork University Hospital, Wilton, Cork, Ireland","the Departments of Physiology (Drs. Markos, Snow, and O\u2019Connell) and Anesthesia and Intensive Care Medicine (Dr. Shorten), University College Cork, Wilton, Cork, Ireland","Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Anesthesia and Intensive Care Medicine (Dr. Halpenny), Mercy Hospital and University College Cork, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I27577105","https://openalex.org/I4210100707"]},{"raw_affiliation_string":"and the Department of Pathology (Dr. Gaffney), St James\u2019s Hospital, Dublin, Ireland","institution_ids":["https://openalex.org/I4210154619"]},{"raw_affiliation_string":"the Department of Biochemistry (Dr. Duggan), Cork University Hospital, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I2802396013"]},{"raw_affiliation_string":"the Departments of Physiology (Drs. Markos, Snow, and O\u2019Connell) and Anesthesia and Intensive Care Medicine (Dr. Shorten), University College Cork, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I27577105"]},{"raw_affiliation_string":"Ireland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063530923","display_name":"H. M. Snow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27577105","display_name":"University College Cork","ror":"https://ror.org/03265fv13","country_code":"IE","type":"education","lineage":["https://openalex.org/I27577105"]},{"id":"https://openalex.org/I2802396013","display_name":"Cork University Hospital","ror":"https://ror.org/04q107642","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2802396013"]},{"id":"https://openalex.org/I4210100707","display_name":"Mercy University Hospital","ror":"https://ror.org/017q2rt66","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210100707"]},{"id":"https://openalex.org/I4210154619","display_name":"St. James's Hospital","ror":"https://ror.org/04c6bry31","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210154619"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Henry M. Snow","raw_affiliation_strings":["From the Department of Anesthesia and Intensive Care Medicine (Dr. Halpenny), Mercy Hospital and University College Cork, Wilton, Cork, Ireland","and the Department of Pathology (Dr. Gaffney), St James\u2019s Hospital, Dublin, Ireland","the Department of Biochemistry (Dr. Duggan), Cork University Hospital, Wilton, Cork, Ireland","the Departments of Physiology (Drs. Markos, Snow, and O\u2019Connell) and Anesthesia and Intensive Care Medicine (Dr. Shorten), University College Cork, Wilton, Cork, Ireland","Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Anesthesia and Intensive Care Medicine (Dr. Halpenny), Mercy Hospital and University College Cork, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I27577105","https://openalex.org/I4210100707"]},{"raw_affiliation_string":"and the Department of Pathology (Dr. Gaffney), St James\u2019s Hospital, Dublin, Ireland","institution_ids":["https://openalex.org/I4210154619"]},{"raw_affiliation_string":"the Department of Biochemistry (Dr. Duggan), Cork University Hospital, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I2802396013"]},{"raw_affiliation_string":"the Departments of Physiology (Drs. Markos, Snow, and O\u2019Connell) and Anesthesia and Intensive Care Medicine (Dr. Shorten), University College Cork, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I27577105"]},{"raw_affiliation_string":"Ireland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109140583","display_name":"Patrick Duggan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27577105","display_name":"University College Cork","ror":"https://ror.org/03265fv13","country_code":"IE","type":"education","lineage":["https://openalex.org/I27577105"]},{"id":"https://openalex.org/I2802396013","display_name":"Cork University Hospital","ror":"https://ror.org/04q107642","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2802396013"]},{"id":"https://openalex.org/I4210100707","display_name":"Mercy University Hospital","ror":"https://ror.org/017q2rt66","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210100707"]},{"id":"https://openalex.org/I4210154619","display_name":"St. James's Hospital","ror":"https://ror.org/04c6bry31","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210154619"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Patrick F. Duggan","raw_affiliation_strings":["From the Department of Anesthesia and Intensive Care Medicine (Dr. Halpenny), Mercy Hospital and University College Cork, Wilton, Cork, Ireland","and the Department of Pathology (Dr. Gaffney), St James\u2019s Hospital, Dublin, Ireland","the Department of Biochemistry (Dr. Duggan), Cork University Hospital, Wilton, Cork, Ireland","the Departments of Physiology (Drs. Markos, Snow, and O\u2019Connell) and Anesthesia and Intensive Care Medicine (Dr. Shorten), University College Cork, Wilton, Cork, Ireland","Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Anesthesia and Intensive Care Medicine (Dr. Halpenny), Mercy Hospital and University College Cork, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I27577105","https://openalex.org/I4210100707"]},{"raw_affiliation_string":"and the Department of Pathology (Dr. Gaffney), St James\u2019s Hospital, Dublin, Ireland","institution_ids":["https://openalex.org/I4210154619"]},{"raw_affiliation_string":"the Department of Biochemistry (Dr. Duggan), Cork University Hospital, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I2802396013"]},{"raw_affiliation_string":"the Departments of Physiology (Drs. Markos, Snow, and O\u2019Connell) and Anesthesia and Intensive Care Medicine (Dr. Shorten), University College Cork, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I27577105"]},{"raw_affiliation_string":"Ireland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068632670","display_name":"Eoin F. Gaffney","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27577105","display_name":"University College Cork","ror":"https://ror.org/03265fv13","country_code":"IE","type":"education","lineage":["https://openalex.org/I27577105"]},{"id":"https://openalex.org/I2802396013","display_name":"Cork University Hospital","ror":"https://ror.org/04q107642","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2802396013"]},{"id":"https://openalex.org/I4210100707","display_name":"Mercy University Hospital","ror":"https://ror.org/017q2rt66","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210100707"]},{"id":"https://openalex.org/I4210154619","display_name":"St. James's Hospital","ror":"https://ror.org/04c6bry31","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210154619"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"E. Gaffney","raw_affiliation_strings":["From the Department of Anesthesia and Intensive Care Medicine (Dr. Halpenny), Mercy Hospital and University College Cork, Wilton, Cork, Ireland","and the Department of Pathology (Dr. Gaffney), St James\u2019s Hospital, Dublin, Ireland","the Department of Biochemistry (Dr. Duggan), Cork University Hospital, Wilton, Cork, Ireland","the Departments of Physiology (Drs. Markos, Snow, and O\u2019Connell) and Anesthesia and Intensive Care Medicine (Dr. Shorten), University College Cork, Wilton, Cork, Ireland","Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Anesthesia and Intensive Care Medicine (Dr. Halpenny), Mercy Hospital and University College Cork, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I27577105","https://openalex.org/I4210100707"]},{"raw_affiliation_string":"and the Department of Pathology (Dr. Gaffney), St James\u2019s Hospital, Dublin, Ireland","institution_ids":["https://openalex.org/I4210154619"]},{"raw_affiliation_string":"the Department of Biochemistry (Dr. Duggan), Cork University Hospital, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I2802396013"]},{"raw_affiliation_string":"the Departments of Physiology (Drs. Markos, Snow, and O\u2019Connell) and Anesthesia and Intensive Care Medicine (Dr. Shorten), University College Cork, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I27577105"]},{"raw_affiliation_string":"Ireland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110065239","display_name":"Damian P. O\u2019Connell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27577105","display_name":"University College Cork","ror":"https://ror.org/03265fv13","country_code":"IE","type":"education","lineage":["https://openalex.org/I27577105"]},{"id":"https://openalex.org/I2802396013","display_name":"Cork University Hospital","ror":"https://ror.org/04q107642","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2802396013"]},{"id":"https://openalex.org/I4210100707","display_name":"Mercy University Hospital","ror":"https://ror.org/017q2rt66","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210100707"]},{"id":"https://openalex.org/I4210154619","display_name":"St. James's Hospital","ror":"https://ror.org/04c6bry31","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210154619"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Damian P. O\u2019Connell","raw_affiliation_strings":["From the Department of Anesthesia and Intensive Care Medicine (Dr. Halpenny), Mercy Hospital and University College Cork, Wilton, Cork, Ireland","and the Department of Pathology (Dr. Gaffney), St James\u2019s Hospital, Dublin, Ireland","the Department of Biochemistry (Dr. Duggan), Cork University Hospital, Wilton, Cork, Ireland","the Departments of Physiology (Drs. Markos, Snow, and O\u2019Connell) and Anesthesia and Intensive Care Medicine (Dr. Shorten), University College Cork, Wilton, Cork, Ireland","Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Anesthesia and Intensive Care Medicine (Dr. Halpenny), Mercy Hospital and University College Cork, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I27577105","https://openalex.org/I4210100707"]},{"raw_affiliation_string":"and the Department of Pathology (Dr. Gaffney), St James\u2019s Hospital, Dublin, Ireland","institution_ids":["https://openalex.org/I4210154619"]},{"raw_affiliation_string":"the Department of Biochemistry (Dr. Duggan), Cork University Hospital, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I2802396013"]},{"raw_affiliation_string":"the Departments of Physiology (Drs. Markos, Snow, and O\u2019Connell) and Anesthesia and Intensive Care Medicine (Dr. Shorten), University College Cork, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I27577105"]},{"raw_affiliation_string":"Ireland","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043118145","display_name":"George Shorten","orcid":"https://orcid.org/0000-0002-6962-9128","observed_orcids":["https://orcid.org/0000-0002-6962-9128"]},"institutions":[{"id":"https://openalex.org/I27577105","display_name":"University College Cork","ror":"https://ror.org/03265fv13","country_code":"IE","type":"education","lineage":["https://openalex.org/I27577105"]},{"id":"https://openalex.org/I2802396013","display_name":"Cork University Hospital","ror":"https://ror.org/04q107642","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2802396013"]},{"id":"https://openalex.org/I4210100707","display_name":"Mercy University Hospital","ror":"https://ror.org/017q2rt66","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210100707"]},{"id":"https://openalex.org/I4210154619","display_name":"St. James's Hospital","ror":"https://ror.org/04c6bry31","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210154619"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"George D. Shorten","raw_affiliation_strings":["From the Department of Anesthesia and Intensive Care Medicine (Dr. Halpenny), Mercy Hospital and University College Cork, Wilton, Cork, Ireland","and the Department of Pathology (Dr. Gaffney), St James\u2019s Hospital, Dublin, Ireland","the Department of Biochemistry (Dr. Duggan), Cork University Hospital, Wilton, Cork, Ireland","the Departments of Physiology (Drs. Markos, Snow, and O\u2019Connell) and Anesthesia and Intensive Care Medicine (Dr. Shorten), University College Cork, Wilton, Cork, Ireland","Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Anesthesia and Intensive Care Medicine (Dr. Halpenny), Mercy Hospital and University College Cork, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I27577105","https://openalex.org/I4210100707"]},{"raw_affiliation_string":"and the Department of Pathology (Dr. Gaffney), St James\u2019s Hospital, Dublin, Ireland","institution_ids":["https://openalex.org/I4210154619"]},{"raw_affiliation_string":"the Department of Biochemistry (Dr. Duggan), Cork University Hospital, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I2802396013"]},{"raw_affiliation_string":"the Departments of Physiology (Drs. Markos, Snow, and O\u2019Connell) and Anesthesia and Intensive Care Medicine (Dr. Shorten), University College Cork, Wilton, Cork, Ireland","institution_ids":["https://openalex.org/I27577105"]},{"raw_affiliation_string":"Ireland","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.879,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.91317829,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"29","issue":"4","first_page":"855","last_page":"860"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.6523000001907349,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.6523000001907349,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.17180000245571136,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11116","display_name":"Trauma, Hemostasis, Coagulopathy, Resuscitation","score":0.1111999973654747,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fenoldopam","display_name":"fenoldopam","score":0.9879999756813049},{"id":"https://openalex.org/keywords/dopamine-agonists","display_name":"dopamine agonists","score":0.7390000224113464},{"id":"https://openalex.org/keywords/renal-blood-flow","display_name":"renal blood flow","score":0.8709999918937683},{"id":"https://openalex.org/keywords/renal-tubular-function","display_name":"renal tubular function","score":0.8579999804496765},{"id":"https://openalex.org/keywords/acute-hypovolemia","display_name":"acute hypovolemia","score":0.921999990940094},{"id":"https://openalex.org/keywords/hypovolemic-shock","display_name":"hypovolemic shock","score":0.9649999737739563},{"id":"https://openalex.org/keywords/urine-output","display_name":"urine output","score":0.6549999713897705},{"id":"https://openalex.org/keywords/creatinine-clearance","display_name":"creatinine clearance","score":0.9599999785423279},{"id":"https://openalex.org/keywords/fractional-excretion-of-sodium","display_name":"fractional excretion of sodium","score":0.9120000004768372},{"id":"https://openalex.org/keywords/renal-perfusion","display_name":"renal perfusion","score":0.5989999771118164},{"id":"https://openalex.org/keywords/renal-hypoperfusion","display_name":"renal hypoperfusion","score":0.47699999809265137},{"id":"https://openalex.org/keywords/dogs","display_name":"dogs","score":0.4300000071525574},{"id":"https://openalex.org/keywords/retransfusion","display_name":"retransfusion","score":0.6190000176429749},{"id":"https://openalex.org/keywords/hemodynamic-stability","display_name":"hemodynamic stability","score":0.6449999809265137},{"id":"https://openalex.org/keywords/cardiac-output","display_name":"cardiac output","score":0.3409999907016754}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9564424753189087},{"id":"https://openalex.org/C2779867896","wikidata":"https://www.wikidata.org/wiki/Q2357007","display_name":"Fenoldopam","level":4,"score":0.9172992706298828},{"id":"https://openalex.org/C2781309813","wikidata":"https://www.wikidata.org/wiki/Q1320276","display_name":"Hypovolemia","level":2,"score":0.8790943622589111},{"id":"https://openalex.org/C142225936","wikidata":"https://www.wikidata.org/wiki/Q1129139","display_name":"Renal blood flow","level":3,"score":0.7352534532546997},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.5889496207237244},{"id":"https://openalex.org/C2781073237","wikidata":"https://www.wikidata.org/wiki/Q2894103","display_name":"Renal circulation","level":4,"score":0.49100688099861145},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.48999324440956116},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.327554851770401},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25864607095718384},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.08057335019111633},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003404","descriptor_name":"Creatinine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007262","descriptor_name":"Infusions, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007684","descriptor_name":"Kidney Tubules","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D007684","descriptor_name":"Kidney Tubules","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D012079","descriptor_name":"Renal Circulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D014665","descriptor_name":"Vasodilator Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D018818","descriptor_name":"Fenoldopam","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D020896","descriptor_name":"Hypovolemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/00003246-200104000-00034","doi":"https://doi.org/10.1097/00003246-200104000-00034","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00003246-200104000-00034","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},{"id":"pmid:11373482","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11373482","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical care medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W235219221","https://openalex.org/W1967929888","https://openalex.org/W1973760111","https://openalex.org/W1975838486","https://openalex.org/W1982628508","https://openalex.org/W1994711516","https://openalex.org/W1996091750","https://openalex.org/W2005788726","https://openalex.org/W2030615738","https://openalex.org/W2030905853","https://openalex.org/W2031714315","https://openalex.org/W2031723450","https://openalex.org/W2033474105","https://openalex.org/W2048655828","https://openalex.org/W2052328910","https://openalex.org/W2056399357","https://openalex.org/W2063123103","https://openalex.org/W2075348344","https://openalex.org/W2122936007","https://openalex.org/W2139044492","https://openalex.org/W2149635465","https://openalex.org/W2171831397","https://openalex.org/W2409179709","https://openalex.org/W2417281462","https://openalex.org/W4236514815","https://openalex.org/W4248586959"],"related_works":["https://openalex.org/W2068604736","https://openalex.org/W433386811","https://openalex.org/W1967930071","https://openalex.org/W2121814637","https://openalex.org/W2003093519","https://openalex.org/W7099294637","https://openalex.org/W3146578937","https://openalex.org/W2096120083","https://openalex.org/W2080945906","https://openalex.org/W2315842348"],"abstract_inverted_index":{"OBJECTIVE:":[0],"It":[1],"was":[2,33,176],"hypothesized":[3],"that":[4,61,291,340],"fenoldopam":[5,39,119,127,149,169,224,293,341],"mesylate,":[6],"a":[7,135,156,344],"selective":[8],"dopamine":[9],"agonist,":[10],"may":[11,342],"preserve":[12],"renal":[13,47,96,327],"perfusion":[14],"and":[15,54,80,103,110,153,185,210,234,246,277,306,325,333],"decrease":[16,68],"tubular":[17,319],"oxygen":[18],"consumption":[19],"during":[20,124,134,155,194,261],"states":[21],"of":[22,30,38,106,118,126,138,148,168,249],"hypoperfusion,":[23],"such":[24],"as":[25],"hypovolemic":[26,196,263],"shock.":[27],"The":[28],"objective":[29],"this":[31],"study":[32],"to":[34,66,205,214,229,238,268,281,297,310,322],"quantify":[35],"the":[36,161,195,199,223,258,262,289,318],"effects":[37],"(0.1":[40,170],"microg":[41,171],"x":[42,44,172,174,273,275,302,304],"kg(-1)":[43,173,274,303],"min(-1))":[45,175],"on":[46],"blood":[48,90,97,183,328],"flow,":[49,98,329],"urine":[50,99,186],"output,":[51,95,100],"creatinine":[52,101],"clearance,":[53,102],"sodium":[55,107,250],"clearance":[56,245],"in":[57,198,222,257,288,347],"pentobarbital":[58],"anesthetized":[59],"dogs":[60,290],"had":[62],"undergone":[63],"partial":[64,143],"exsanguination":[65],"acutely":[67],"cardiac":[69,94],"output.":[70],"DESIGN:":[71],"Prospective,":[72],"randomized,":[73],"controlled":[74],"experiment.":[75],"SETTING:":[76],"University-based":[77],"animal":[78],"laboratory":[79],"research":[81],"unit.":[82],"SUBJECTS:":[83],"Eight":[84],"female":[85],"beagle":[86],"dogs.":[87,162],"INTERVENTIONS:":[88],"Arterial":[89],"pressure,":[91],"heart":[92],"rate,":[93,332],"fractional":[104,247],"excretion":[105,248],"were":[108],"measured":[109],"calculated":[111],"at":[112],"four":[113],"times:":[114],"a)":[115],"before":[116],"infusion":[117,125,147],"or":[120,128,150],"normal":[121,129,151],"saline;":[122,152],"b)":[123],"saline":[130],"(1":[131],"hr);":[132],"c)":[133],"90-min":[136],"period":[137,158,197,264],"hypovolemia":[139,324],"(induced":[140],"by":[141],"acute":[142,348],"exsanguination),":[144],"with":[145,179],"concurrent":[146],"d)":[154],"1-hr":[157],"after":[159],"retransfusing":[160],"MEASUREMENTS":[163],"AND":[164],"MAIN":[165],"RESULTS:":[166],"Administration":[167],"not":[177,221,287],"associated":[178],"hemodynamic":[180],"instability.":[181],"Renal":[182],"flow":[184],"output":[187],"decreased":[188,251],"significantly":[189,252],"from":[190,253],"baseline":[191,254],"(p":[192,255],"<.01)":[193,256],"placebo":[200,259],"group":[201,225,260],"(72":[202],"+/-":[203,207,212,216,227,231,236,240,266,270,279,283,295,299,308,312],"20":[204],"47":[206],"6":[208],"mL/min":[209,233],"0.26":[211],"0.15":[213],"0.08":[215],"0.05":[217,241],"mL/min,":[218,242],"respectively)":[219,285],"but":[220,286],"(75":[226],"14":[228],"73":[230],"17":[232],"0.3":[235],"0.19":[237],"0.14":[239],"respectively).":[243,314],"Creatinine":[244],"(3.0":[265,294],"0.4":[267],"1.8":[269],"0.8":[271],"mL":[272,301],"min(-1)":[276,305],"1.7%":[278,311],"0.9%":[280],"0.4%":[282],"0.2%,":[284],"received":[292],"1.0":[296],"2.9":[298],"0.5":[300],"1.9%":[307],"1.1%":[309],"2.7%,":[313],"CONCLUSIONS:":[315],"Fenoldopam":[316],"ablated":[317],"prerenal":[320],"response":[321],"profound":[323],"maintained":[326],"glomerular":[330],"filtration":[331],"natriuresis":[334],"without":[335],"causing":[336],"hypotension.":[337],"This":[338],"suggests":[339],"have":[343],"renoprotective":[345],"effect":[346],"ischemic":[349],"injury.":[350]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
