{"id":"https://openalex.org/W2017301392","doi":"https://doi.org/10.1152/jn.00547.2003","title":"Factors Underlying Bursting Behavior in a Network of Cultured Hippocampal Neurons Exposed to Zero Magnesium","display_name":"Factors Underlying Bursting Behavior in a Network of Cultured Hippocampal Neurons Exposed to Zero Magnesium","publication_year":2004,"publication_date":"2004-02-01","ids":{"openalex":"https://openalex.org/W2017301392","doi":"https://doi.org/10.1152/jn.00547.2003","mag":"2017301392","pmid":"https://pubmed.ncbi.nlm.nih.gov/14534286","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2892720"},"language":"en","primary_location":{"id":"doi:10.1152/jn.00547.2003","doi":"https://doi.org/10.1152/jn.00547.2003","is_oa":false,"landing_page_url":"https://doi.org/10.1152/jn.00547.2003","pdf_url":null,"source":{"id":"https://openalex.org/S142952003","display_name":"Journal of Neurophysiology","issn_l":"0022-3077","issn":["0022-3077","1522-1598"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurophysiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2892720","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064431117","display_name":"Patrick S. Mangan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick S. Mangan","raw_affiliation_strings":["Department of Neurology, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908","Department of Neurology, University of Virginia, Health Sciences Center, Charlottesville, Virginia 22908, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908","institution_ids":["https://openalex.org/I51556381"]},{"raw_affiliation_string":"Department of Neurology, University of Virginia, Health Sciences Center, Charlottesville, Virginia 22908, USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077470899","display_name":"Jaideep Kapur","orcid":"https://orcid.org/0000-0002-8608-1352","observed_orcids":["https://orcid.org/0000-0002-8608-1352"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jaideep Kapur","raw_affiliation_strings":["Department of Neurology, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908","institution_ids":["https://openalex.org/I51556381"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I51556381"],"apc_list":null,"apc_paid":null,"fwci":2.3445,"has_fulltext":false,"cited_by_count":89,"citation_normalized_percentile":{"value":0.87628943,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"91","issue":"2","first_page":"946","last_page":"957"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuronal-bursting","display_name":"neuronal bursting","score":0.6589999794960022},{"id":"https://openalex.org/keywords/hippocampal-pyramidal-neurons","display_name":"hippocampal pyramidal neurons","score":0.9229999780654907},{"id":"https://openalex.org/keywords/nmda-receptor","display_name":"NMDA receptor","score":0.8420000076293945},{"id":"https://openalex.org/keywords/ampa-receptors","display_name":"AMPA receptors","score":0.8119999766349792},{"id":"https://openalex.org/keywords/miniature-excitatory-postsynaptic-currents","display_name":"miniature excitatory postsynaptic currents","score":0.9190000295639038},{"id":"https://openalex.org/keywords/synaptic-transmission","display_name":"synaptic transmission","score":0.5730000138282776},{"id":"https://openalex.org/keywords/presynaptic-release-probability","display_name":"presynaptic release probability","score":0.625},{"id":"https://openalex.org/keywords/quantal-content","display_name":"quantal content","score":0.7649999856948853},{"id":"https://openalex.org/keywords/synaptophysin","display_name":"synaptophysin","score":0.8460000157356262},{"id":"https://openalex.org/keywords/nr1-subunit","display_name":"NR1 subunit","score":0.8410000205039978},{"id":"https://openalex.org/keywords/neuronal-hyperexcitability","display_name":"neuronal hyperexcitability","score":0.9190000295639038},{"id":"https://openalex.org/keywords/neuronal-network-excitability","display_name":"neuronal network excitability","score":0.7739999890327454},{"id":"https://openalex.org/keywords/culture-density","display_name":"culture density","score":0.7229999899864197},{"id":"https://openalex.org/keywords/d-apv","display_name":"D-APV","score":0.7580000162124634},{"id":"https://openalex.org/keywords/dnqx","display_name":"DNQX","score":0.9950000047683716}],"concepts":[{"id":"https://openalex.org/C195221683","wikidata":"https://www.wikidata.org/wiki/Q5000649","display_name":"Bursting","level":2,"score":0.8694449663162231},{"id":"https://openalex.org/C67018056","wikidata":"https://www.wikidata.org/wiki/Q414896","display_name":"NMDA receptor","level":3,"score":0.6834613680839539},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.669620156288147},{"id":"https://openalex.org/C160268369","wikidata":"https://www.wikidata.org/wiki/Q295251","display_name":"AMPA receptor","level":4,"score":0.668276309967041},{"id":"https://openalex.org/C2777075645","wikidata":"https://www.wikidata.org/wiki/Q4386525","display_name":"DNQX","level":5,"score":0.6126416921615601},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5967769622802734},{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.4797590672969818},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.4777890145778656},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46459126472473145},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.4415958821773529},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.44015151262283325},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4098323881626129},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3542833924293518},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2669534683227539},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08545634150505066}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011810","descriptor_name":"Quinoxalines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019706","descriptor_name":"Excitatory Postsynaptic Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D019706","descriptor_name":"Excitatory Postsynaptic Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1152/jn.00547.2003","doi":"https://doi.org/10.1152/jn.00547.2003","is_oa":false,"landing_page_url":"https://doi.org/10.1152/jn.00547.2003","pdf_url":null,"source":{"id":"https://openalex.org/S142952003","display_name":"Journal of Neurophysiology","issn_l":"0022-3077","issn":["0022-3077","1522-1598"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurophysiology","raw_type":"journal-article"},{"id":"pmid:14534286","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14534286","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurophysiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2892720","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2892720","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Neurophysiol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2892720","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2892720","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Neurophysiol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G155011101","display_name":null,"funder_award_id":"NS40337","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G3351217131","display_name":"EVOLUTION OF ALTERED INHIBITION IN EPILEPSY","funder_award_id":"R29NS037192","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G429832266","display_name":null,"funder_award_id":"NS-02081","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G4309353363","display_name":"Treatment of Status Epilepticus","funder_award_id":"R01NS040337","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G7600672076","display_name":"UNDERSTANDING STATUS EPILEPTICUS","funder_award_id":"K02NS002081","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G7858836811","display_name":"Neurosteroid Regulation of Seizures","funder_award_id":"R01NS044370","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G8807174066","display_name":null,"funder_award_id":"NS37192","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":85,"referenced_works":["https://openalex.org/W140487675","https://openalex.org/W327219297","https://openalex.org/W1481927180","https://openalex.org/W1532576817","https://openalex.org/W1554611458","https://openalex.org/W1571034236","https://openalex.org/W1575372500","https://openalex.org/W1585412507","https://openalex.org/W1586953019","https://openalex.org/W1590954967","https://openalex.org/W1591829725","https://openalex.org/W1675918816","https://openalex.org/W1723579215","https://openalex.org/W1828807460","https://openalex.org/W1836848727","https://openalex.org/W1873773379","https://openalex.org/W1940449329","https://openalex.org/W1965013830","https://openalex.org/W1967878023","https://openalex.org/W1970849523","https://openalex.org/W1973995482","https://openalex.org/W1975503980","https://openalex.org/W1977695003","https://openalex.org/W1986780859","https://openalex.org/W1987700551","https://openalex.org/W1987990912","https://openalex.org/W1991436409","https://openalex.org/W1997199005","https://openalex.org/W2001849190","https://openalex.org/W2002676420","https://openalex.org/W2003614957","https://openalex.org/W2006203683","https://openalex.org/W2009324487","https://openalex.org/W2012955910","https://openalex.org/W2013010178","https://openalex.org/W2017541628","https://openalex.org/W2019016101","https://openalex.org/W2019341946","https://openalex.org/W2028274352","https://openalex.org/W2028848126","https://openalex.org/W2029126307","https://openalex.org/W2035082265","https://openalex.org/W2037921808","https://openalex.org/W2039005933","https://openalex.org/W2039524707","https://openalex.org/W2039959072","https://openalex.org/W2052795247","https://openalex.org/W2058068338","https://openalex.org/W2058148599","https://openalex.org/W2059602156","https://openalex.org/W2064088453","https://openalex.org/W2070864731","https://openalex.org/W2078432475","https://openalex.org/W2078449479","https://openalex.org/W2079109477","https://openalex.org/W2083420532","https://openalex.org/W2085556169","https://openalex.org/W2087350062","https://openalex.org/W2088374028","https://openalex.org/W2088976329","https://openalex.org/W2090662268","https://openalex.org/W2092045031","https://openalex.org/W2094694532","https://openalex.org/W2113770179","https://openalex.org/W2116129077","https://openalex.org/W2117242960","https://openalex.org/W2127087627","https://openalex.org/W2145869886","https://openalex.org/W2148343974","https://openalex.org/W2164477294","https://openalex.org/W2166759337","https://openalex.org/W2171697328","https://openalex.org/W2237466815","https://openalex.org/W2290923177","https://openalex.org/W2304512189","https://openalex.org/W2309556032","https://openalex.org/W2395193086","https://openalex.org/W2402932179","https://openalex.org/W2412877205","https://openalex.org/W2416186588","https://openalex.org/W2416499772","https://openalex.org/W2433525795","https://openalex.org/W2571918371","https://openalex.org/W4247446264","https://openalex.org/W4313025241"],"related_works":["https://openalex.org/W2037723094","https://openalex.org/W2015505108","https://openalex.org/W4413478102","https://openalex.org/W1981394664","https://openalex.org/W1984702255","https://openalex.org/W2032609319","https://openalex.org/W2411016212","https://openalex.org/W2014977824","https://openalex.org/W2039255680","https://openalex.org/W2298642101"],"abstract_inverted_index":{"Factors":[0],"contributing":[1],"to":[2,67,71,122,204],"reduced":[3,87,128],"magnesium-induced":[4,88],"neuronal":[5,124,201],"action":[6,36,149],"potential":[7,37,150],"bursting":[8,151],"were":[9,45,79],"investigated":[10],"in":[11,86,117,139,152,184],"primary":[12],"hippocampal":[13],"cell":[14],"culture":[15,20],"at":[16],"high":[17],"and":[18,69,167,198,206],"low":[19],"density.":[21],"In":[22],"nominally":[23],"zero":[24,111,140,153],"external":[25],"magnesium":[26,112,154],"medium,":[27],"pyramidal":[28],"neurons":[29,162],"from":[30,143],"high-density":[31],"cultures":[32,145],"produced":[33],"recurrent":[34],"spontaneous":[35],"bursts":[38,44],"superimposed":[39],"on":[40],"prolonged":[41],"depolarizations.":[42],"These":[43,176],"partially":[46],"attenuated":[47],"by":[48,93,127,173],"the":[49,72,94,97,101,105],"NMDA":[50,84,102,194],"receptor":[51,74,103],"antagonist":[52,75],"d-APV.":[53],"Pharmacological":[54],"analysis":[55],"of":[56,83,96,100,189,200,208],"miniature":[57],"excitatory":[58],"postsynaptic":[59],"currents":[60],"(EPSCs)":[61],"revealed":[62],"2":[63],"components:":[64],"one":[65],"sensitive":[66],"d-APV":[68],"another":[70],"AMPA":[73],"DNQX.":[76],"The":[77],"components":[78],"kinetically":[80],"distinct.":[81],"Participation":[82],"receptors":[85],"synaptic":[89],"events":[90],"was":[91,136],"supported":[92],"localization":[95],"NR1":[98],"subunit":[99],"with":[104],"presynaptic":[106],"vesicular":[107],"protein":[108],"synaptophysin.":[109],"Presynaptically,":[110],"induced":[113,126],"a":[114],"significant":[115],"increase":[116],"EPSC":[118,159],"frequency":[119],"likely":[120],"attributable":[121],"increased":[123,138,158],"hyperexcitability":[125],"membrane":[129],"surface":[130],"charge":[131],"screening.":[132],"Mean":[133],"quantal":[134],"content":[135],"significantly":[137],"magnesium.":[141],"Cells":[142],"low-density":[144],"did":[146,156],"not":[147],"exhibit":[148],"but":[155],"show":[157],"frequency.":[160],"Low-density":[161],"had":[163],"less":[164],"synaptophysin":[165],"immunofluorescence":[166],"fewer":[168],"active":[169],"synapses":[170],"as":[171],"determined":[172],"FM1-43":[174],"analysis.":[175],"results":[177],"demonstrate":[178],"that":[179],"multiple":[180],"factors":[181],"are":[182],"involved":[183],"network":[185,210],"bursting.":[186],"Increased":[187],"probability":[188],"transmitter":[190],"release":[191],"presynaptically,":[192],"enhanced":[193],"receptor-mediated":[195],"excitability":[196],"postsynaptically,":[197],"extent":[199],"interconnectivity":[202],"contribute":[203],"initiation":[205],"maintenance":[207],"elevated":[209],"excitability.":[211]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}