{"id":"https://openalex.org/W2017288458","doi":"https://doi.org/10.1016/j.molimm.2011.06.256","title":"Mannose binding lectin as a target for cerebral ischemic injury","display_name":"Mannose binding lectin as a target for cerebral ischemic injury","publication_year":2011,"publication_date":"2011-07-25","ids":{"openalex":"https://openalex.org/W2017288458","doi":"https://doi.org/10.1016/j.molimm.2011.06.256","mag":"2017288458"},"language":"en","primary_location":{"id":"doi:10.1016/j.molimm.2011.06.256","doi":"https://doi.org/10.1016/j.molimm.2011.06.256","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molimm.2011.06.256","pdf_url":null,"source":{"id":"https://openalex.org/S92126311","display_name":"Molecular Immunology","issn_l":"0161-5890","issn":["0161-5890","1872-9142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071087943","display_name":"Franca Orsini","orcid":"https://orcid.org/0000-0001-7415-9936","observed_orcids":["https://orcid.org/0000-0001-7415-9936"]},"institutions":[{"id":"https://openalex.org/I19630809","display_name":"Mario Negri Institute for Pharmacological Research","ror":"https://ror.org/05aspc753","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I19630809","https://openalex.org/I4210110338","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"F. Orsini","raw_affiliation_strings":["Mario Negri Institute, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mario Negri Institute, Milan, Italy","institution_ids":["https://openalex.org/I19630809"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003192910","display_name":"Sara Parrella","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19630809","display_name":"Mario Negri Institute for Pharmacological Research","ror":"https://ror.org/05aspc753","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I19630809","https://openalex.org/I4210110338","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S. Parrella","raw_affiliation_strings":["Mario Negri Institute, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mario Negri Institute, Milan, Italy","institution_ids":["https://openalex.org/I19630809"]}]},{"author_position":"middle","author":{"id":null,"display_name":"P. Villa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19630809","display_name":"Mario Negri Institute for Pharmacological Research","ror":"https://ror.org/05aspc753","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I19630809","https://openalex.org/I4210110338","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"P. Villa","raw_affiliation_strings":["Mario Negri Institute, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mario Negri Institute, Milan, Italy","institution_ids":["https://openalex.org/I19630809"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024686163","display_name":"Elisa Roncati Zanier","orcid":"https://orcid.org/0000-0002-3011-8718","observed_orcids":["https://orcid.org/0000-0002-3011-8718"]},"institutions":[{"id":"https://openalex.org/I19630809","display_name":"Mario Negri Institute for Pharmacological Research","ror":"https://ror.org/05aspc753","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I19630809","https://openalex.org/I4210110338","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"E.R.Z.R. Zanier","raw_affiliation_strings":["Mario Negri Institute, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mario Negri Institute, Milan, Italy","institution_ids":["https://openalex.org/I19630809"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020613201","display_name":"Raffaella Gesuete","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19630809","display_name":"Mario Negri Institute for Pharmacological Research","ror":"https://ror.org/05aspc753","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I19630809","https://openalex.org/I4210110338","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"R. Gesuete","raw_affiliation_strings":["Mario Negri Institute, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mario Negri Institute, Milan, Italy","institution_ids":["https://openalex.org/I19630809"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050543823","display_name":"Matteo Stravalaci","orcid":"https://orcid.org/0000-0002-5636-4204","observed_orcids":["https://orcid.org/0000-0002-5636-4204"]},"institutions":[{"id":"https://openalex.org/I19630809","display_name":"Mario Negri Institute for Pharmacological Research","ror":"https://ror.org/05aspc753","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I19630809","https://openalex.org/I4210110338","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. Stravalaci","raw_affiliation_strings":["Mario Negri Institute, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mario Negri Institute, Milan, Italy","institution_ids":["https://openalex.org/I19630809"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068332931","display_name":"Roberta Ottria","orcid":"https://orcid.org/0000-0003-3379-0582","observed_orcids":["https://orcid.org/0000-0003-3379-0582"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"R. Ottria","raw_affiliation_strings":["University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090451162","display_name":"Jos\u00e9 J. Reina","orcid":"https://orcid.org/0000-0001-7936-4250","observed_orcids":["https://orcid.org/0000-0001-7936-4250"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"J. Reina","raw_affiliation_strings":["University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030314665","display_name":"Gregory L. Stahl","orcid":"https://orcid.org/0000-0002-4805-8119","observed_orcids":["https://orcid.org/0000-0002-4805-8119"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G. Stahl","raw_affiliation_strings":["Harvard Institute of Medicine, Boston, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard Institute of Medicine, Boston, United States","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027270759","display_name":"Anna Bernardi","orcid":"https://orcid.org/0000-0002-1258-2007","observed_orcids":["https://orcid.org/0000-0002-1258-2007"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Bernardi","raw_affiliation_strings":["University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007066407","display_name":"Marco Gobbi","orcid":"https://orcid.org/0000-0003-1014-6225","observed_orcids":["https://orcid.org/0000-0003-1014-6225"]},"institutions":[{"id":"https://openalex.org/I19630809","display_name":"Mario Negri Institute for Pharmacological Research","ror":"https://ror.org/05aspc753","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I19630809","https://openalex.org/I4210110338","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. Gobbi","raw_affiliation_strings":["Mario Negri Institute, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mario Negri Institute, Milan, Italy","institution_ids":["https://openalex.org/I19630809"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031143795","display_name":"Maria Grazia De Simoni","orcid":"https://orcid.org/0000-0001-6695-5297","observed_orcids":["https://orcid.org/0000-0001-6695-5297"]},"institutions":[{"id":"https://openalex.org/I19630809","display_name":"Mario Negri Institute for Pharmacological Research","ror":"https://ror.org/05aspc753","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I19630809","https://openalex.org/I4210110338","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"M.G. De Simoni","raw_affiliation_strings":["Mario Negri Institute, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mario Negri Institute, Milan, Italy","institution_ids":["https://openalex.org/I19630809"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5031143795"],"corresponding_institution_ids":["https://openalex.org/I19630809"],"apc_list":{"value":3340,"currency":"USD","value_usd":3340},"apc_paid":null,"fwci":0.1413,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.52853437,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"48","issue":"14","first_page":"1677","last_page":"1677"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.9394999742507935,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.9394999742507935,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.013000000268220901,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.012799999676644802,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mannose-binding-lectin","display_name":"mannose-binding lectin","score":0.9129999876022339},{"id":"https://openalex.org/keywords/cerebral-ischemia","display_name":"cerebral ischemia","score":0.8949999809265137},{"id":"https://openalex.org/keywords/ischemic-brain-injury","display_name":"ischemic brain injury","score":0.8270000219345093},{"id":"https://openalex.org/keywords/lectins","display_name":"lectins","score":0.4180000126361847},{"id":"https://openalex.org/keywords/complement-system","display_name":"complement system","score":0.6159999966621399},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.7630000114440918}],"concepts":[{"id":"https://openalex.org/C189413060","wikidata":"https://www.wikidata.org/wiki/Q415443","display_name":"Mannan-binding lectin","level":3,"score":0.8490383625030518},{"id":"https://openalex.org/C2780758401","wikidata":"https://www.wikidata.org/wiki/Q408693","display_name":"Lectin","level":2,"score":0.6814303398132324},{"id":"https://openalex.org/C2775887612","wikidata":"https://www.wikidata.org/wiki/Q10809118","display_name":"Mannose","level":2,"score":0.5715972781181335},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3516588807106018},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3060871362686157},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2756785750389099},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2086033821105957}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.molimm.2011.06.256","doi":"https://doi.org/10.1016/j.molimm.2011.06.256","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molimm.2011.06.256","pdf_url":null,"source":{"id":"https://openalex.org/S92126311","display_name":"Molecular Immunology","issn_l":"0161-5890","issn":["0161-5890","1872-9142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Immunology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2752372184","https://openalex.org/W2068511665","https://openalex.org/W2017272483","https://openalex.org/W3024343605","https://openalex.org/W1978053766","https://openalex.org/W2362775804","https://openalex.org/W3011903744","https://openalex.org/W2069758620","https://openalex.org/W2093965039","https://openalex.org/W2340046930"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}