{"id":"https://openalex.org/W2017262674","doi":"https://doi.org/10.1016/j.bpc.2010.06.003","title":"Modulation of quaternary structure of S100 proteins by calcium ions","display_name":"Modulation of quaternary structure of S100 proteins by calcium ions","publication_year":2010,"publication_date":"2010-06-24","ids":{"openalex":"https://openalex.org/W2017262674","doi":"https://doi.org/10.1016/j.bpc.2010.06.003","mag":"2017262674","pmid":"https://pubmed.ncbi.nlm.nih.gov/20621410","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2926197"},"language":"en","primary_location":{"id":"doi:10.1016/j.bpc.2010.06.003","doi":"https://doi.org/10.1016/j.bpc.2010.06.003","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bpc.2010.06.003","pdf_url":null,"source":{"id":"https://openalex.org/S63395545","display_name":"Biophysical Chemistry","issn_l":"0301-4622","issn":["0301-4622","1873-4200"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2926197/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036344267","display_name":"Werner W. Streicher","orcid":"https://orcid.org/0000-0002-2425-5839","observed_orcids":["https://orcid.org/0000-0002-2425-5839"]},"institutions":[{"id":"https://openalex.org/I165799507","display_name":"Rensselaer Polytechnic Institute","ror":"https://ror.org/01rtyzb94","country_code":"US","type":"education","lineage":["https://openalex.org/I165799507"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Werner W. Streicher","raw_affiliation_strings":["Center for Biotechnology and Interdisciplinary Studies and Department of Biology, Rensselaer Polytechnic Institute, Troy, NY 12065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biotechnology and Interdisciplinary Studies and Department of Biology, Rensselaer Polytechnic Institute, Troy, NY 12065, USA","institution_ids":["https://openalex.org/I165799507"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103518251","display_name":"Mar\u00eda M. L\u00f3pez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165799507","display_name":"Rensselaer Polytechnic Institute","ror":"https://ror.org/01rtyzb94","country_code":"US","type":"education","lineage":["https://openalex.org/I165799507"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maria M. Lopez","raw_affiliation_strings":["Center for Biotechnology and Interdisciplinary Studies and Department of Biology, Rensselaer Polytechnic Institute, 110 8th Street, Troy, NY 12065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biotechnology and Interdisciplinary Studies and Department of Biology, Rensselaer Polytechnic Institute, 110 8th Street, Troy, NY 12065, USA","institution_ids":["https://openalex.org/I165799507"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056229406","display_name":"George I. Makhatadze","orcid":"https://orcid.org/0000-0003-4565-1264","observed_orcids":["https://orcid.org/0000-0003-4565-1264"]},"institutions":[{"id":"https://openalex.org/I165799507","display_name":"Rensselaer Polytechnic Institute","ror":"https://ror.org/01rtyzb94","country_code":"US","type":"education","lineage":["https://openalex.org/I165799507"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"George I. Makhatadze","raw_affiliation_strings":["Center for Biotechnology and Interdisciplinary Studies and Department of Biology, Rensselaer Polytechnic Institute, 110 8th Street, Troy, NY 12065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biotechnology and Interdisciplinary Studies and Department of Biology, Rensselaer Polytechnic Institute, 110 8th Street, Troy, NY 12065, USA","institution_ids":["https://openalex.org/I165799507"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5056229406"],"corresponding_institution_ids":["https://openalex.org/I165799507"],"apc_list":{"value":3720,"currency":"USD","value_usd":3720},"apc_paid":null,"fwci":1.2493,"has_fulltext":false,"cited_by_count":57,"citation_normalized_percentile":{"value":0.75930676,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"151","issue":"3","first_page":"181","last_page":"186"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12030","display_name":"S100 Proteins and Annexins","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12030","display_name":"S100 Proteins and Annexins","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11908","display_name":"Protein Interaction Studies and Fluorescence Analysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/s100-protein","display_name":"S-100 protein","score":1.0},{"id":"https://openalex.org/keywords/calcium-binding","display_name":"calcium binding","score":0.9340000152587891},{"id":"https://openalex.org/keywords/quaternary-structure","display_name":"quaternary structure","score":0.9240000247955322},{"id":"https://openalex.org/keywords/tetramer-formation","display_name":"tetramer formation","score":0.6899999976158142},{"id":"https://openalex.org/keywords/homodimer","display_name":"homodimer","score":0.9110000133514404},{"id":"https://openalex.org/keywords/conformational-change","display_name":"conformational change","score":0.7829999923706055},{"id":"https://openalex.org/keywords/protein-oligomerization","display_name":"protein oligomerization","score":0.8119999766349792},{"id":"https://openalex.org/keywords/macromolecular-crowding","display_name":"macromolecular crowding","score":0.9700000286102295},{"id":"https://openalex.org/keywords/s100a1","display_name":"S100A1","score":0.7059999704360962},{"id":"https://openalex.org/keywords/s100b","display_name":"S100B","score":0.925000011920929},{"id":"https://openalex.org/keywords/s100p","display_name":"S100P","score":0.9409999847412109},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.5220000147819519}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.93836909532547},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.6803001761436462},{"id":"https://openalex.org/C7927669","wikidata":"https://www.wikidata.org/wiki/Q898529","display_name":"Protein quaternary structure","level":4,"score":0.6614100337028503},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5733751654624939},{"id":"https://openalex.org/C122229402","wikidata":"https://www.wikidata.org/wiki/Q5018802","display_name":"Calcium-binding protein","level":3,"score":0.5649110674858093},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.4723968207836151},{"id":"https://openalex.org/C132677234","wikidata":"https://www.wikidata.org/wiki/Q3273544","display_name":"Structural motif","level":2,"score":0.4698939323425293},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4392208755016327},{"id":"https://openalex.org/C42086223","wikidata":"https://www.wikidata.org/wiki/Q24723907","display_name":"EF hand","level":4,"score":0.4266894459724426},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.06840649247169495},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009418","descriptor_name":"S100 Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009418","descriptor_name":"S100 Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014461","descriptor_name":"Ultracentrifugation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019540","descriptor_name":"Area Under Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020836","descriptor_name":"Protein Structure, Quaternary","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D055503","descriptor_name":"Protein Multimerization","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.bpc.2010.06.003","doi":"https://doi.org/10.1016/j.bpc.2010.06.003","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bpc.2010.06.003","pdf_url":null,"source":{"id":"https://openalex.org/S63395545","display_name":"Biophysical Chemistry","issn_l":"0301-4622","issn":["0301-4622","1873-4200"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Chemistry","raw_type":"journal-article"},{"id":"pmid:20621410","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20621410","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2926197","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2926197/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biophys Chem","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2926197","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2926197/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biophys Chem","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G7103744948","display_name":"Role of Helix Formation in Mediating Protein-Protein Interactions","funder_award_id":"R01GM054537","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W173643440","https://openalex.org/W1566315211","https://openalex.org/W1581563868","https://openalex.org/W1618858311","https://openalex.org/W1971770269","https://openalex.org/W1973199370","https://openalex.org/W1980271338","https://openalex.org/W1980759649","https://openalex.org/W1989591478","https://openalex.org/W1990322093","https://openalex.org/W1990552480","https://openalex.org/W1991648097","https://openalex.org/W1995166771","https://openalex.org/W1997507890","https://openalex.org/W1998826717","https://openalex.org/W2003739799","https://openalex.org/W2008794259","https://openalex.org/W2018759985","https://openalex.org/W2028001817","https://openalex.org/W2030016620","https://openalex.org/W2030506720","https://openalex.org/W2044992731","https://openalex.org/W2045433754","https://openalex.org/W2060762906","https://openalex.org/W2061681936","https://openalex.org/W2066469381","https://openalex.org/W2073205505","https://openalex.org/W2080981546","https://openalex.org/W2087413172","https://openalex.org/W2087524055","https://openalex.org/W2095663905","https://openalex.org/W2097914474","https://openalex.org/W2099666638","https://openalex.org/W2101324624","https://openalex.org/W2103878505","https://openalex.org/W2111811354","https://openalex.org/W2123404680","https://openalex.org/W2129379280","https://openalex.org/W2140847300","https://openalex.org/W2158019963","https://openalex.org/W4252589303","https://openalex.org/W6676715008"],"related_works":["https://openalex.org/W2008794259","https://openalex.org/W2912105446","https://openalex.org/W2042331074","https://openalex.org/W2071635262","https://openalex.org/W2071263658","https://openalex.org/W2524328073","https://openalex.org/W2066469381","https://openalex.org/W2073205505","https://openalex.org/W2042197782","https://openalex.org/W6983726136"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}