{"id":"https://openalex.org/W2017256127","doi":"https://doi.org/10.1152/ajpgi.00020.2012","title":"Ferritin upregulates hepatic expression of bone morphogenetic protein 6 and hepcidin in mice","display_name":"Ferritin upregulates hepatic expression of bone morphogenetic protein 6 and hepcidin in mice","publication_year":2012,"publication_date":"2012-04-21","ids":{"openalex":"https://openalex.org/W2017256127","doi":"https://doi.org/10.1152/ajpgi.00020.2012","mag":"2017256127","pmid":"https://pubmed.ncbi.nlm.nih.gov/22517766","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3378091"},"language":"en","primary_location":{"id":"doi:10.1152/ajpgi.00020.2012","doi":"https://doi.org/10.1152/ajpgi.00020.2012","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpgi.00020.2012","pdf_url":null,"source":{"id":"https://openalex.org/S34136372","display_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","issn_l":"0193-1857","issn":["0193-1857","1522-1547"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/articles/PMC3378091","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101620485","display_name":"Qi Feng","orcid":"https://orcid.org/0000-0002-0272-493X","observed_orcids":["https://orcid.org/0000-0002-0272-493X"]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qi Feng","raw_affiliation_strings":["Department of Pediatrics, Saint Louis University School of Medicine, St. Louis, Missouri;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Saint Louis University School of Medicine, St. Louis, Missouri;","institution_ids":["https://openalex.org/I47838141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009975619","display_name":"Mary C. Migas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary C. Migas","raw_affiliation_strings":["Department of Pediatrics, Saint Louis University School of Medicine, St. Louis, Missouri;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Saint Louis University School of Medicine, St. Louis, Missouri;","institution_ids":["https://openalex.org/I47838141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022331909","display_name":"Abd\u00fcl Waheed","orcid":"https://orcid.org/0000-0001-5812-8822","observed_orcids":["https://orcid.org/0000-0001-5812-8822"]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Abdul Waheed","raw_affiliation_strings":["Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri","institution_ids":["https://openalex.org/I47838141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110636913","display_name":"Robert S. Britton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert S. Britton","raw_affiliation_strings":["Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, Missouri; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, Missouri; and","institution_ids":["https://openalex.org/I47838141"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050061791","display_name":"Robert E. Fleming","orcid":"https://orcid.org/0000-0003-0154-4483","observed_orcids":["https://orcid.org/0000-0003-0154-4483"]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert E. Fleming","raw_affiliation_strings":["Department of Pediatrics, Saint Louis University School of Medicine, St. Louis, Missouri;","Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Saint Louis University School of Medicine, St. Louis, Missouri;","institution_ids":["https://openalex.org/I47838141"]},{"raw_affiliation_string":"Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri","institution_ids":["https://openalex.org/I47838141"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5050061791"],"corresponding_institution_ids":["https://openalex.org/I47838141"],"apc_list":null,"apc_paid":null,"fwci":4.0889,"has_fulltext":false,"cited_by_count":49,"citation_normalized_percentile":{"value":0.94308861,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"302","issue":"12","first_page":"G1397","last_page":"G1404"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11418","display_name":"Plant Micronutrient Interactions and Effects","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10915","display_name":"Trace Elements in Health","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ferritin","display_name":"ferritin","score":0.9580000042915344},{"id":"https://openalex.org/keywords/bmp6","display_name":"BMP6","score":0.9580000042915344},{"id":"https://openalex.org/keywords/hepcidin","display_name":"hepcidin","score":0.9929999709129333},{"id":"https://openalex.org/keywords/iron-status","display_name":"iron status","score":0.5820000171661377},{"id":"https://openalex.org/keywords/hepatic-gene-expression","display_name":"hepatic gene expression","score":0.8059999942779541},{"id":"https://openalex.org/keywords/sinusoidal-lining-cells","display_name":"sinusoidal lining cells","score":0.7720000147819519},{"id":"https://openalex.org/keywords/liver-iron","display_name":"liver iron","score":0.3919999897480011},{"id":"https://openalex.org/keywords/ferric-ammonium-citrate","display_name":"ferric ammonium citrate","score":0.9990000128746033},{"id":"https://openalex.org/keywords/iron-transport","display_name":"iron transport","score":0.4009999930858612},{"id":"https://openalex.org/keywords/juvenile-mice","display_name":"juvenile mice","score":0.5120000243186951}],"concepts":[{"id":"https://openalex.org/C2776768029","wikidata":"https://www.wikidata.org/wiki/Q14882371","display_name":"Hepcidin","level":3,"score":0.947319746017456},{"id":"https://openalex.org/C2778319317","wikidata":"https://www.wikidata.org/wiki/Q22327449","display_name":"Ferritin","level":2,"score":0.7652044296264648},{"id":"https://openalex.org/C181628713","wikidata":"https://www.wikidata.org/wiki/Q14903748","display_name":"Bone morphogenetic protein 6","level":5,"score":0.7343119382858276},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6693853139877319},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6385936141014099},{"id":"https://openalex.org/C176891718","wikidata":"https://www.wikidata.org/wiki/Q1997459","display_name":"Hepatic stellate cell","level":2,"score":0.4136624336242676},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4122006297111511},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38781803846359253},{"id":"https://openalex.org/C31507581","wikidata":"https://www.wikidata.org/wiki/Q425383","display_name":"Bone morphogenetic protein","level":3,"score":0.3291160464286804},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.26604506373405457},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23624977469444275},{"id":"https://openalex.org/C125349252","wikidata":"https://www.wikidata.org/wiki/Q14903102","display_name":"Bone morphogenetic protein 7","level":4,"score":0.1824665069580078},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.15180703997612},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1080816388130188}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005293","descriptor_name":"Ferritins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014168","descriptor_name":"Transferrin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015854","descriptor_name":"Up-Regulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D022781","descriptor_name":"Hepatocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D022781","descriptor_name":"Hepatocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D023181","descriptor_name":"Antimicrobial Cationic Peptides","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D023181","descriptor_name":"Antimicrobial Cationic Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055418","descriptor_name":"Bone Morphogenetic Protein 6","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D055418","descriptor_name":"Bone Morphogenetic Protein 6","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D064451","descriptor_name":"Hepcidins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1152/ajpgi.00020.2012","doi":"https://doi.org/10.1152/ajpgi.00020.2012","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpgi.00020.2012","pdf_url":null,"source":{"id":"https://openalex.org/S34136372","display_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","issn_l":"0193-1857","issn":["0193-1857","1522-1547"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2678240","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3378091","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:22517766","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22517766","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of physiology. Gastrointestinal and liver physiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3378091","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3378091/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Physiol Gastrointest Liver Physiol","raw_type":"Text"},{"id":"mag:2186206115","doi":null,"is_oa":false,"landing_page_url":"https://ajpgi.physiology.org/content/ajpgi/early/2012/04/13/ajpgi.00020.2012.full.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2678240","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3378091","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6926427637","display_name":"Role of Transferrin Receptor 2 in Iron Homeostasis","funder_award_id":"R01DK063016","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000889466","display_name":"Integrative Liver Cell Core","funder_award_id":"R24AA012885","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G9000899538","display_name":"Southern California Research Center for ALPD and Cirrhosis","funder_award_id":"P50AA011999","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"}],"funders":[{"id":"https://openalex.org/F4320312021","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08"},{"id":"https://openalex.org/F4320337330","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":72,"referenced_works":["https://openalex.org/W160412982","https://openalex.org/W1526845901","https://openalex.org/W1551118417","https://openalex.org/W1822911650","https://openalex.org/W1893281021","https://openalex.org/W1969300611","https://openalex.org/W1970672739","https://openalex.org/W1970714562","https://openalex.org/W1971995316","https://openalex.org/W1975057603","https://openalex.org/W1980557108","https://openalex.org/W1981407334","https://openalex.org/W1983949401","https://openalex.org/W1986956929","https://openalex.org/W1989527051","https://openalex.org/W1991410899","https://openalex.org/W1995594551","https://openalex.org/W1997977268","https://openalex.org/W2002176673","https://openalex.org/W2004552248","https://openalex.org/W2005510371","https://openalex.org/W2005664965","https://openalex.org/W2006358233","https://openalex.org/W2008380967","https://openalex.org/W2015894758","https://openalex.org/W2018540348","https://openalex.org/W2020076923","https://openalex.org/W2024882338","https://openalex.org/W2025878569","https://openalex.org/W2026203736","https://openalex.org/W2029265259","https://openalex.org/W2037635331","https://openalex.org/W2037708841","https://openalex.org/W2038985973","https://openalex.org/W2039318988","https://openalex.org/W2040024685","https://openalex.org/W2044056480","https://openalex.org/W2051504691","https://openalex.org/W2052138406","https://openalex.org/W2054149566","https://openalex.org/W2055560694","https://openalex.org/W2057183171","https://openalex.org/W2059778114","https://openalex.org/W2064287360","https://openalex.org/W2069512202","https://openalex.org/W2070655717","https://openalex.org/W2072993305","https://openalex.org/W2073354871","https://openalex.org/W2075302528","https://openalex.org/W2082509603","https://openalex.org/W2090618731","https://openalex.org/W2094516222","https://openalex.org/W2105350808","https://openalex.org/W2107704801","https://openalex.org/W2113632923","https://openalex.org/W2115541385","https://openalex.org/W2117339718","https://openalex.org/W2118668970","https://openalex.org/W2125809753","https://openalex.org/W2127797915","https://openalex.org/W2147951331","https://openalex.org/W2153170511","https://openalex.org/W2155410241","https://openalex.org/W2161653019","https://openalex.org/W2163216489","https://openalex.org/W2164942127","https://openalex.org/W2168789347","https://openalex.org/W2172197126","https://openalex.org/W2340014015","https://openalex.org/W2398018741","https://openalex.org/W2416817279","https://openalex.org/W2420005891"],"related_works":["https://openalex.org/W1994456769","https://openalex.org/W2064540468","https://openalex.org/W2052759694","https://openalex.org/W2024047211","https://openalex.org/W3211922070","https://openalex.org/W4297196258","https://openalex.org/W7098183437","https://openalex.org/W3123172250","https://openalex.org/W2969419538","https://openalex.org/W4403629210"],"abstract_inverted_index":{"Hepcidin":[0],"is":[1,30],"a":[2],"hepatocellular":[3],"hormone":[4],"that":[5,117,215,226],"inhibits":[6],"the":[7,35,47,56,176,181],"release":[8],"of":[9,22,46,51,58,82,85,105,190,232],"iron":[10,28,49,64,86,162,178],"from":[11,163],"certain":[12],"cell":[13],"populations,":[14],"including":[15],"enterocytes":[16],"and":[17,60,77,92,102,107,142,153,175,223],"reticuloendothelial":[18],"cells.":[19,187],"The":[20],"regulation":[21,57,231],"hepcidin":[23],"(HAMP)":[24],"gene":[25],"expression":[26,62,104,120,135,155,189],"by":[27,34,63,89,129,147],"status":[29,50],"mediated":[31],"in":[32,66,122,138,156,180,193,202],"part":[33],"signaling":[36],"molecule":[37],"bone":[38],"morphogenetic":[39],"protein":[40],"6":[41,112],"(BMP6).":[42],"We":[43,115,213],"took":[44],"advantage":[45],"low":[48],"juvenile":[52],"mice":[53,158],"to":[54,99,124,140,184,230],"characterize":[55],"Bmp6":[59,106,119,152,170,191,221,233],"Hamp1":[61,108,134,154,236],"administered":[65,98,173],"three":[67],"forms:":[68],"1)":[69],"ferri-transferrin":[70],"(Fe-Tf),":[71],"2)":[72],"ferric":[73],"ammonium":[74],"citrate":[75],"(FAC),":[76],"3)":[78],"liver":[79,182,197,227],"ferritin.":[80],"Each":[81],"these":[83],"forms":[84],"enters":[87],"cells":[88,198,205],"distinct":[90],"mechanisms":[91],"chemical":[93],"forms.":[94],"Iron":[95],"was":[96,110,127,145,199],"parenterally":[97],"10-day-old":[100],"mice,":[101],"hepatic":[103,118,220],"mRNAs":[109],"measured":[111],"h":[113],"later.":[114],"observed":[116],"increased":[121,137,151],"response":[123,139],"ferritin":[125,141,150,164,174,218,228],"but":[126,144],"unchanged":[128],"Fe-Tf":[130,143],"or":[131],"FAC.":[132,148],"Hepatic":[133],"likewise":[136],"decreased":[146,166],"Exogenous":[149],"older":[157],"as":[159],"well.":[160],"Removing":[161],"markedly":[165],"its":[167],"effect":[168],"on":[169],"expression.":[171],"Exogenously":[172],"derived":[177],"localized":[179],"primarily":[183],"sinusoidal":[185,203],"lining":[186,204],"Moreover,":[188],"mRNA":[192],"isolated":[194],"adult":[195],"rodent":[196],"much":[200],"higher":[201],"than":[206],"hepatocytes":[207],"(endothelial":[208],">>":[209],"stellate":[210],">":[211],"Kupffer).":[212],"conclude":[214],"exogenous":[216],"iron-containing":[217],"upregulates":[219],"expression,":[222],"we":[224],"speculate":[225],"contributes":[229],"and,":[234],"thus,":[235],"genes.":[237]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}