{"id":"https://openalex.org/W2017230604","doi":"https://doi.org/10.2337/diacare.21.10.1632","title":"Descriptive Epidemiology of IDDM in Hokkaido, Japan: The Childhood IDDM Hokkaido Registry","display_name":"Descriptive Epidemiology of IDDM in Hokkaido, Japan: The Childhood IDDM Hokkaido Registry","publication_year":1998,"publication_date":"1998-10-01","ids":{"openalex":"https://openalex.org/W2017230604","doi":"https://doi.org/10.2337/diacare.21.10.1632","mag":"2017230604","pmid":"https://pubmed.ncbi.nlm.nih.gov/9773722"},"language":"en","primary_location":{"id":"doi:10.2337/diacare.21.10.1632","doi":"https://doi.org/10.2337/diacare.21.10.1632","is_oa":false,"landing_page_url":"https://doi.org/10.2337/diacare.21.10.1632","pdf_url":null,"source":{"id":"https://openalex.org/S49878492","display_name":"Diabetes Care","issn_l":"0149-5992","issn":["0149-5992","1935-5548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103136231","display_name":"Nobuo Matsuura","orcid":"https://orcid.org/0000-0001-5931-140X","observed_orcids":["https://orcid.org/0000-0001-5931-140X"]},"institutions":[{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuo Matsuura","raw_affiliation_strings":["Department of Pediatrics, Kitasato University\u2008Sagamihara"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Kitasato University\u2008Sagamihara","institution_ids":["https://openalex.org/I64189623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103544125","display_name":"Katsuhiro Fukuda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]},{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsuhiro Fukuda","raw_affiliation_strings":["Department of Pediatrics, Hokkaido University\u2008Sapporo","Department of Public Health, Kurume University School of Medicine\u2008Kurume, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Hokkaido University\u2008Sapporo","institution_ids":["https://openalex.org/I205349734"]},{"raw_affiliation_string":"Department of Public Health, Kurume University School of Medicine\u2008Kurume, Japan","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034566801","display_name":"Akimasa Okuno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I147809708","display_name":"Asahikawa Medical University","ror":"https://ror.org/025h9kw94","country_code":"JP","type":"education","lineage":["https://openalex.org/I147809708"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akimasa Okuno","raw_affiliation_strings":["Asahikawa Medical College\u2008Asahikawa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Asahikawa Medical College\u2008Asahikawa","institution_ids":["https://openalex.org/I147809708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054547232","display_name":"Shohei Harada","orcid":"https://orcid.org/0009-0008-5422-3054","observed_orcids":["https://orcid.org/0009-0008-5422-3054","https://orcid.org/0009-0004-4275-9012"]},"institutions":[{"id":"https://openalex.org/I4210158475","display_name":"Hokkaido Institute of Public Health","ror":"https://ror.org/050hwd209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210158475"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shohei Harada","raw_affiliation_strings":["Hokkaido Institute of Public Health\u2008Sapporo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hokkaido Institute of Public Health\u2008Sapporo","institution_ids":["https://openalex.org/I4210158475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006512683","display_name":"Naoki Fukushima","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Naoki Fukushima","raw_affiliation_strings":["Sapporo Municipal Hospital\u2008Sapporo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sapporo Municipal Hospital\u2008Sapporo","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082294364","display_name":"Akemi Koike","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210104287","display_name":"Tonan Hospital","ror":"https://ror.org/01gtph098","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210104287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akemi Koike","raw_affiliation_strings":["Tonan General Hospital\u2008Sapporo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tonan General Hospital\u2008Sapporo","institution_ids":["https://openalex.org/I4210104287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033673866","display_name":"Yoshiya Ito","orcid":"https://orcid.org/0000-0001-7905-6661","observed_orcids":["https://orcid.org/0000-0001-7905-6661"]},"institutions":[{"id":"https://openalex.org/I147809708","display_name":"Asahikawa Medical University","ror":"https://ror.org/025h9kw94","country_code":"JP","type":"education","lineage":["https://openalex.org/I147809708"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshiya Ito","raw_affiliation_strings":["Asahikawa Medical College\u2008Asahikawa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Asahikawa Medical College\u2008Asahikawa","institution_ids":["https://openalex.org/I147809708"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016348517","display_name":"Tomoyuki Hotsubo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141882310","display_name":"Sapporo Medical University","ror":"https://ror.org/01h7cca57","country_code":"JP","type":"education","lineage":["https://openalex.org/I141882310"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoyuki Hotsubo","raw_affiliation_strings":["Sapporo Medical University School of Medicine\u2008Sapporo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sapporo Medical University School of Medicine\u2008Sapporo","institution_ids":["https://openalex.org/I141882310"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9414,"has_fulltext":false,"cited_by_count":46,"citation_normalized_percentile":{"value":0.70596214,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"21","issue":"10","first_page":"1632","last_page":"1636"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.019700000062584877,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pediatric-type-1-diabetes","display_name":"type 1 diabetes in children","score":0.7120000123977661},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.843999981880188},{"id":"https://openalex.org/keywords/age-distribution","display_name":"age distribution","score":0.6449999809265137},{"id":"https://openalex.org/keywords/family-history-of-diabetes","display_name":"family history of diabetes","score":0.9990000128746033},{"id":"https://openalex.org/keywords/seasonal-variation","display_name":"seasonal variation","score":0.9010000228881836},{"id":"https://openalex.org/keywords/temporal-trends","display_name":"temporal trends","score":0.796999990940094},{"id":"https://openalex.org/keywords/japanese-children","display_name":"Japanese children","score":0.6710000038146973},{"id":"https://openalex.org/keywords/hokkaido","display_name":"Hokkaido","score":0.925000011920929}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8641064167022705},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.7533761262893677},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.7496246099472046},{"id":"https://openalex.org/C2781179581","wikidata":"https://www.wikidata.org/wiki/Q2857712","display_name":"Family history","level":2,"score":0.6613056063652039},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6487435102462769},{"id":"https://openalex.org/C73269764","wikidata":"https://www.wikidata.org/wiki/Q954529","display_name":"Poisson regression","level":3,"score":0.607390284538269},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.5953992605209351},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5733304023742676},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5330632328987122},{"id":"https://openalex.org/C986699","wikidata":"https://www.wikidata.org/wiki/Q7939","display_name":"El Ni\u00f1o","level":2,"score":0.4228890836238861},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.15957874059677124},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1379333734512329},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.08766606450080872},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.07714211940765381},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012621","descriptor_name":"Seasons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017668","descriptor_name":"Age of Onset","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017678","descriptor_name":"Sex Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2337/diacare.21.10.1632","doi":"https://doi.org/10.2337/diacare.21.10.1632","is_oa":false,"landing_page_url":"https://doi.org/10.2337/diacare.21.10.1632","pdf_url":null,"source":{"id":"https://openalex.org/S49878492","display_name":"Diabetes Care","issn_l":"0149-5992","issn":["0149-5992","1935-5548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"journal-article"},{"id":"pmid:9773722","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9773722","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes care","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2017071037","https://openalex.org/W2112707055","https://openalex.org/W2078653577","https://openalex.org/W2056139065","https://openalex.org/W1974705143","https://openalex.org/W2121614609","https://openalex.org/W2046491401","https://openalex.org/W1965676496","https://openalex.org/W2439512510","https://openalex.org/W2070393952"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"identify":[2],"the":[3,55,78,82,143,151,195,238,246,251],"incidence":[4,126,171,212],"of":[5,14,20,45,81,110,134,161,201,215,232,253],"IDDM":[6,22,48,57,163,203,216,254],"with":[7,127,228],"regard":[8,128],"to":[9,38,64,77,92,121,129,175,259],"sex,":[10,130],"age,":[11,131],"family":[12,132,230],"history":[13,133,181,231],"diabetes,":[15,135],"season,":[16,136],"and":[17,94,99,112,137,189,241],"5-year":[18,190],"period":[19,139,153],"childhood":[21,202],"among":[23,71,255],"children":[24,257],"ages":[25],"0-14":[26],"years":[27],"from":[28,36,62,70,204],"a":[29,89,208],"population-based":[30],"epidemiological":[31,199],"study":[32,83,200],"in":[33,50,106,125,169,185,217,237],"Hokkaido,":[34,98],"Japan,":[35],"1973":[37,63],"1992.":[39,65],"RESEARCH":[40],"DESIGN":[41],"AND":[42],"METHODS:":[43],"Registration":[44],"all":[46],"new":[47],"cases":[49,67,103,156],"Hokkaido":[51,58],"was":[52,119],"conducted":[53],"by":[54,142,147],"Childhood":[56],"Registry":[59],"Study":[60],"Group":[61],"The":[66,115],"were":[68,75,104,140,164,172],"selected":[69],"1)":[72],"patients":[73,86,101],"who":[74,87],"admitted":[76],"member":[79],"hospitals":[80,93],"group,":[84],"2)":[85],"answered":[88],"questionnaire":[90],"distributed":[91],"diabetic":[95],"clinics":[96],"throughout":[97],"3)":[100],"whose":[102],"recorded":[105],"free-treatment":[107],"medical":[108],"records":[109],"urban":[111],"rural":[113],"districts.":[114],"case":[116],"ascertainment":[117],"rate":[118],"estimated":[120],"be":[122,260],"100%.":[123],"Differences":[124],"year":[138],"analyzed":[141],"Poisson":[144],"regression":[145],"analysis":[146],"GENMOD.":[148],"RESULTS:":[149],"During":[150],"20-year":[152],"studied,":[154],"396":[155],"(181":[157],"boys,":[158],"215":[159],"girls)":[160],"abrupt-onset":[162],"registered.":[165],"Statistically":[166],"significant":[167],"differences":[168],"annual":[170,211],"found":[173],"according":[174],"sex":[176],"(female),":[177],"age":[178],"(8-14":[179],"years),":[180,226],"(having":[182],"no":[183,229],"diabetes":[184,233,235],"family),":[186],"season":[187],"(spring),":[188],"period.":[191],"CONCLUSIONS:":[192],"This":[193],"is":[194],"first":[196],"population-based,":[197],"long-term":[198],"Japan.":[205],"We":[206],"observed":[207],"significantly":[209],"higher":[210],"(per":[213],"100,000/year)":[214],"female":[218],"subjects":[219,227],"(1.81),":[220],"older":[221],"age-groups":[222],"(2.25":[223],"for":[224],"8-14":[225],"(1.26),":[234],"onset":[236],"spring":[239],"(2.20),":[240],"an":[242],"increased":[243],"trend":[244],"over":[245],"20":[247],"years.":[248],"In":[249],"addition,":[250],"heterogeneity":[252],"Japanese":[256],"needs":[258],"elucidated.":[261]},"counts_by_year":[{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}