{"id":"https://openalex.org/W2017227413","doi":"https://doi.org/10.2147/mder.s51591","title":"Transmyocardial revascularization devices: technology update","display_name":"Transmyocardial revascularization devices: technology update","publication_year":2014,"publication_date":"2014-12-01","ids":{"openalex":"https://openalex.org/W2017227413","doi":"https://doi.org/10.2147/mder.s51591","mag":"2017227413","pmid":"https://pubmed.ncbi.nlm.nih.gov/25565905","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4274152"},"language":"en","primary_location":{"id":"doi:10.2147/mder.s51591","doi":"https://doi.org/10.2147/mder.s51591","is_oa":true,"landing_page_url":"https://doi.org/10.2147/mder.s51591","pdf_url":"https://www.dovepress.com/getfile.php?fileID=22924","source":{"id":"https://openalex.org/S2738211502","display_name":"Medical Devices Evidence and Research","issn_l":"1179-1470","issn":["1179-1470"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Devices: Evidence and Research","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.dovepress.com/getfile.php?fileID=22924","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110125671","display_name":"Keith A. Horvath","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Keith Horvath","raw_affiliation_strings":["Cardiothoracic Surgery Research Program, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiothoracic Surgery Research Program, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064572659","display_name":"Bogdan A. Kindzelski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bogdan Kindzelski","raw_affiliation_strings":["Cardiothoracic Surgery Research Program, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiothoracic Surgery Research Program, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079363193","display_name":"Yifu Zhou","orcid":"https://orcid.org/0000-0002-0403-289X","observed_orcids":["https://orcid.org/0000-0002-0403-289X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yifu Zhou","raw_affiliation_strings":["Cardiothoracic Surgery Research Program, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiothoracic Surgery Research Program, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5110125671"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210106489"],"apc_list":{"value":2320,"currency":"USD","value_usd":2320},"apc_paid":{"value":2320,"currency":"USD","value_usd":2320},"fwci":0.3775,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.32488943,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"8","issue":null,"first_page":"11","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.5464000105857849,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.5464000105857849,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.24449999630451202,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.18039999902248383,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transmyocardial-laser-revascularization","display_name":"transmyocardial laser revascularization","score":0.9819999933242798},{"id":"https://openalex.org/keywords/holmium-yag-laser","display_name":"holmium laser","score":0.8500000238418579},{"id":"https://openalex.org/keywords/co2-laser","display_name":"CO2 laser","score":0.9980000257492065},{"id":"https://openalex.org/keywords/diffuse-coronary-artery-disease","display_name":"diffuse coronary artery disease","score":0.9340000152587891},{"id":"https://openalex.org/keywords/refractory-angina","display_name":"refractory angina","score":0.8309999704360962},{"id":"https://openalex.org/keywords/myocardial-perfusion","display_name":"myocardial perfusion","score":0.8199999928474426},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.9039999842643738},{"id":"https://openalex.org/keywords/coronary-artery-bypass-grafting","display_name":"coronary artery bypass grafting","score":0.9449999928474426},{"id":"https://openalex.org/keywords/laser-tissue-interaction","display_name":"laser-tissue interaction","score":0.7620000243186951},{"id":"https://openalex.org/keywords/device-safety-and-efficacy","display_name":"device safety and efficacy","score":0.7319999933242798}],"concepts":[{"id":"https://openalex.org/C2779464278","wikidata":"https://www.wikidata.org/wiki/Q7317735","display_name":"Revascularization","level":3,"score":0.5277272462844849},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4871070384979248},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4460141956806183},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38286179304122925},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.33227211236953735},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.11125066876411438}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.2147/mder.s51591","doi":"https://doi.org/10.2147/mder.s51591","is_oa":true,"landing_page_url":"https://doi.org/10.2147/mder.s51591","pdf_url":"https://www.dovepress.com/getfile.php?fileID=22924","source":{"id":"https://openalex.org/S2738211502","display_name":"Medical Devices Evidence and Research","issn_l":"1179-1470","issn":["1179-1470"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Devices: Evidence and Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3254871","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4274152","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4274152","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4274152","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Med Devices (Auckl)","raw_type":"Text"},{"id":"pmid:25565905","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25565905","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical devices (Auckland, N.Z.)","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.2147/mder.s51591","doi":"https://doi.org/10.2147/mder.s51591","is_oa":true,"landing_page_url":"https://doi.org/10.2147/mder.s51591","pdf_url":"https://www.dovepress.com/getfile.php?fileID=22924","source":{"id":"https://openalex.org/S2738211502","display_name":"Medical Devices Evidence and Research","issn_l":"1179-1470","issn":["1179-1470"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Devices: Evidence and Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2017227413.pdf","grobid_xml":"https://content.openalex.org/works/W2017227413.grobid-xml"},"referenced_works_count":102,"referenced_works":["https://openalex.org/W9689657","https://openalex.org/W24381907","https://openalex.org/W203955511","https://openalex.org/W308622453","https://openalex.org/W309191832","https://openalex.org/W1541791922","https://openalex.org/W1727751797","https://openalex.org/W1728471291","https://openalex.org/W1778727239","https://openalex.org/W1830033591","https://openalex.org/W1963574121","https://openalex.org/W1966098050","https://openalex.org/W1968523086","https://openalex.org/W1973558097","https://openalex.org/W1975417724","https://openalex.org/W1976750233","https://openalex.org/W1981311457","https://openalex.org/W1981724886","https://openalex.org/W1986175856","https://openalex.org/W1986214440","https://openalex.org/W1986928524","https://openalex.org/W1989997373","https://openalex.org/W1994366819","https://openalex.org/W1998298543","https://openalex.org/W1999534840","https://openalex.org/W2000326886","https://openalex.org/W2000600255","https://openalex.org/W2009197347","https://openalex.org/W2011404343","https://openalex.org/W2017424364","https://openalex.org/W2019447887","https://openalex.org/W2021224652","https://openalex.org/W2027596785","https://openalex.org/W2028216375","https://openalex.org/W2028343918","https://openalex.org/W2031298236","https://openalex.org/W2037621217","https://openalex.org/W2038188842","https://openalex.org/W2039590042","https://openalex.org/W2043511382","https://openalex.org/W2045557344","https://openalex.org/W2047786522","https://openalex.org/W2048735911","https://openalex.org/W2050253393","https://openalex.org/W2050688225","https://openalex.org/W2051704515","https://openalex.org/W2051987769","https://openalex.org/W2057445402","https://openalex.org/W2058663490","https://openalex.org/W2060131789","https://openalex.org/W2060948651","https://openalex.org/W2061517694","https://openalex.org/W2062357022","https://openalex.org/W2062411823","https://openalex.org/W2065222643","https://openalex.org/W2065761648","https://openalex.org/W2065833580","https://openalex.org/W2075341833","https://openalex.org/W2085977158","https://openalex.org/W2089211131","https://openalex.org/W2096493223","https://openalex.org/W2098232644","https://openalex.org/W2098892229","https://openalex.org/W2102619901","https://openalex.org/W2103165076","https://openalex.org/W2105044153","https://openalex.org/W2106840224","https://openalex.org/W2112174413","https://openalex.org/W2112980095","https://openalex.org/W2113024986","https://openalex.org/W2121737503","https://openalex.org/W2135491318","https://openalex.org/W2137800154","https://openalex.org/W2138258915","https://openalex.org/W2138369468","https://openalex.org/W2141289234","https://openalex.org/W2144495909","https://openalex.org/W2149431577","https://openalex.org/W2152843042","https://openalex.org/W2154115881","https://openalex.org/W2159376400","https://openalex.org/W2160213837","https://openalex.org/W2161456369","https://openalex.org/W2162298965","https://openalex.org/W2164223534","https://openalex.org/W2164506013","https://openalex.org/W2168328477","https://openalex.org/W2314520776","https://openalex.org/W2320666430","https://openalex.org/W2320925392","https://openalex.org/W2339007776","https://openalex.org/W2404757325","https://openalex.org/W2411777572","https://openalex.org/W2418317482","https://openalex.org/W3021386255","https://openalex.org/W3025288164","https://openalex.org/W4231726812","https://openalex.org/W4236535087","https://openalex.org/W4237928409","https://openalex.org/W4241208135","https://openalex.org/W4245506961","https://openalex.org/W4249549775"],"related_works":["https://openalex.org/W4366068972","https://openalex.org/W2422047336","https://openalex.org/W2046883662","https://openalex.org/W2015876045","https://openalex.org/W2418588281","https://openalex.org/W4236735078","https://openalex.org/W2406706883","https://openalex.org/W2990192998","https://openalex.org/W2418811166","https://openalex.org/W2056625652"],"abstract_inverted_index":{"Transmyocardial":[0],"laser":[1,28,43,92,189],"revascularization":[2],"(TMR)":[3],"emerged":[4],"as":[5,142,151],"treatment":[6],"modality":[7],"for":[8,54,123,193],"patients":[9],"with":[10,73,118,157,201,204],"diffuse":[11],"coronary":[12,158],"artery":[13,159],"disease":[14],"not":[15],"amendable":[16],"to":[17,36,66,71,84,131,184],"percutaneous":[18],"or":[19,136],"surgical":[20],"revascularization.":[21],"The":[22,60,178],"procedure":[23],"entails":[24],"the":[25,48,74,90,113,139,143,186,194],"creation":[26],"of":[27,108,112,180,198],"channels":[29],"within":[30,138],"ischemic":[31],"myocardium":[32,114],"in":[33,64,104,155,173],"an":[34],"effort":[35],"better":[37],"perfuse":[38],"these":[39,124],"areas.":[40],"Currently,":[41],"two":[42,61,91,187],"devices":[44,62,190],"are":[45],"approved":[46,188],"by":[47],"US":[49],"Food":[50],"and":[51,58,77,110,154,171,191,196],"Drug":[52],"Administration":[53],"TMR":[55,147,167],"-":[56],"holmium:yttrium-aluminum-garnet":[57],"CO2.":[59],"differ":[63],"regard":[65],"energy":[67],"outputs,":[68],"wavelengths,":[69],"ability":[70],"synchronize":[72],"heart":[75],"cycle,":[76],"laser-tissue":[78],"interactions.":[79],"These":[80],"differences":[81],"have":[82,97,115,126,164],"led":[83],"studies":[85,163],"showing":[86],"different":[87],"efficacies":[88],"between":[89],"devices.":[93],"Over":[94],"50,000":[95],"procedures":[96],"been":[98,116,127,149],"performed":[99],"worldwide":[100],"using":[101],"TMR.":[102,119],"Improvements":[103],"angina":[105,174],"stages,":[106],"quality":[107],"life,":[109],"perfusion":[111],"demonstrated":[117,165],"Although":[120],"several":[121],"mechanisms":[122],"improvements":[125],"suggested,":[128],"evidence":[129,192],"points":[130],"new":[132],"blood":[133],"vessel":[134],"formation,":[135],"angiogenesis,":[137],"treated":[140],"myocardium,":[141],"major":[144],"contributory":[145],"factor.":[146],"has":[148],"used":[150],"sole":[152],"therapy":[153],"combination":[156],"bypass":[160],"grafting.":[161],"Clinical":[162],"that":[166],"is":[168,183],"both":[169],"safe":[170],"effective":[172],"relief":[175],"long":[176],"term.":[177],"objective":[179],"this":[181,205],"review":[182],"present":[185],"safety":[195],"efficacy":[197],"TMR,":[199],"along":[200],"future":[202],"directions":[203],"technology.":[206]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":3}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2016-06-24T00:00:00"}