{"id":"https://openalex.org/W2017225353","doi":"https://doi.org/10.1074/jbc.271.26.15743","title":"Octamer Binding Factors and Their Coactivator Can Activate the Murine PU.1 (spi-1) Promoter","display_name":"Octamer Binding Factors and Their Coactivator Can Activate the Murine PU.1 (spi-1) Promoter","publication_year":1996,"publication_date":"1996-06-01","ids":{"openalex":"https://openalex.org/W2017225353","doi":"https://doi.org/10.1074/jbc.271.26.15743","mag":"2017225353","pmid":"https://pubmed.ncbi.nlm.nih.gov/8663022"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.271.26.15743","doi":"https://doi.org/10.1074/jbc.271.26.15743","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.271.26.15743","pdf_url":"http://www.jbc.org/article/S0021925818361210/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.jbc.org/article/S0021925818361210/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5105159563","display_name":"Huimin Chen","orcid":"https://orcid.org/0000-0003-0329-8175","observed_orcids":["https://orcid.org/0000-0003-0329-8175"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hui-min Chen","raw_affiliation_strings":["Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA","Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100425978","display_name":"Pu Zhang","orcid":"https://orcid.org/0000-0001-6349-013X","observed_orcids":["https://orcid.org/0000-0001-6349-013X","https://orcid.org/0009-0008-0501-4854"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pu Zhang","raw_affiliation_strings":["Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007253657","display_name":"Hanna S. Radomska","orcid":"https://orcid.org/0000-0001-6370-7765","observed_orcids":["https://orcid.org/0000-0001-6370-7765"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hanna S. Radomska","raw_affiliation_strings":["Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114045527","display_name":"Christopher J. Hetherington","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher J. Hetherington","raw_affiliation_strings":["Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084311979","display_name":"Dong\u2010Er Zhang","orcid":"https://orcid.org/0000-0003-2541-6443","observed_orcids":["https://orcid.org/0000-0003-2541-6443"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dong-Er Zhang","raw_affiliation_strings":["Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056687452","display_name":"Daniel Geoffrey Tenen","orcid":"https://orcid.org/0000-0002-6423-3888","observed_orcids":["https://orcid.org/0000-0002-6423-3888"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Daniel G. Tenen","raw_affiliation_strings":["Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology/Oncology Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts 02215","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5056687452"],"corresponding_institution_ids":["https://openalex.org/I136199984"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":1.1359,"has_fulltext":true,"cited_by_count":59,"citation_normalized_percentile":{"value":0.76788132,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"271","issue":"26","first_page":"15743","last_page":"15752"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pu-1","display_name":"PU.1","score":0.9139999747276306},{"id":"https://openalex.org/keywords/spi-1","display_name":"SPI-1","score":0.753000020980835},{"id":"https://openalex.org/keywords/ets-transcription-factors","display_name":"ETS transcription factors","score":0.7609999775886536},{"id":"https://openalex.org/keywords/oct-1","display_name":"Oct-1","score":0.9779999852180481},{"id":"https://openalex.org/keywords/oct-2","display_name":"Oct-2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bob-1","display_name":"BOB.1","score":0.9390000104904175},{"id":"https://openalex.org/keywords/oca-b","display_name":"OCA-B","score":0.9559999704360962},{"id":"https://openalex.org/keywords/transcriptional-coactivator","display_name":"transcriptional coactivator","score":0.8399999737739563},{"id":"https://openalex.org/keywords/promoter-activation","display_name":"promoter activation","score":0.7670000195503235},{"id":"https://openalex.org/keywords/myeloid-cells","display_name":"myeloid cells","score":0.8320000171661377},{"id":"https://openalex.org/keywords/sp1-binding-site","display_name":"Sp1 binding site","score":0.9100000262260437},{"id":"https://openalex.org/keywords/autoregulatory-feedback-loop","display_name":"autoregulatory loop","score":0.9419999718666077},{"id":"https://openalex.org/keywords/cell-type-specific-transcription","display_name":"cell-type-specific transcription","score":0.6650000214576721}],"concepts":[{"id":"https://openalex.org/C77445288","wikidata":"https://www.wikidata.org/wiki/Q637488","display_name":"Coactivator","level":4,"score":0.9040706157684326},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6102949380874634},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5817914009094238},{"id":"https://openalex.org/C107824862","wikidata":"https://www.wikidata.org/wiki/Q616005","display_name":"Binding site","level":2,"score":0.5478659272193909},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5190937519073486},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.5025374889373779},{"id":"https://openalex.org/C2777366897","wikidata":"https://www.wikidata.org/wiki/Q847482","display_name":"HeLa","level":3,"score":0.5005531311035156},{"id":"https://openalex.org/C2779282312","wikidata":"https://www.wikidata.org/wiki/Q1956561","display_name":"Myeloid","level":2,"score":0.4791088104248047},{"id":"https://openalex.org/C161733203","wikidata":"https://www.wikidata.org/wiki/Q911828","display_name":"Reporter gene","level":4,"score":0.46957775950431824},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.45428064465522766},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3973381221294403},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.29982563853263855},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.2765079140663147},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.25403663516044617},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1411205232143402}],"mesh":[{"descriptor_ui":"D000099232","descriptor_name":"Proto-Oncogene Protein Spi-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015533","descriptor_name":"Transcriptional Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015534","descriptor_name":"Trans-Activators","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D050811","descriptor_name":"Octamer Transcription Factor-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050813","descriptor_name":"Octamer Transcription Factor-2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051863","descriptor_name":"Host Cell Factor C1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1074/jbc.271.26.15743","doi":"https://doi.org/10.1074/jbc.271.26.15743","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.271.26.15743","pdf_url":"http://www.jbc.org/article/S0021925818361210/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:8663022","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8663022","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1074/jbc.271.26.15743","doi":"https://doi.org/10.1074/jbc.271.26.15743","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.271.26.15743","pdf_url":"http://www.jbc.org/article/S0021925818361210/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2234737544","display_name":null,"funder_award_id":"CA 41456","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3403973982","display_name":null,"funder_award_id":"CA 59589","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4667527894","display_name":"Molecular Biology of Human Myeloid Differentiation","funder_award_id":"R01CA041456","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5355342602","display_name":"CD14 REGULATION BY MONOCYTE DIFFERENTIATION &CYTOKINES","funder_award_id":"7r29ca059589-06","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2017225353.pdf","grobid_xml":"https://content.openalex.org/works/W2017225353.grobid-xml"},"referenced_works_count":71,"referenced_works":["https://openalex.org/W39844064","https://openalex.org/W43784428","https://openalex.org/W58171456","https://openalex.org/W100497966","https://openalex.org/W155831425","https://openalex.org/W1493816460","https://openalex.org/W1540456190","https://openalex.org/W1541937812","https://openalex.org/W1560430223","https://openalex.org/W1599437019","https://openalex.org/W1833742808","https://openalex.org/W1875148047","https://openalex.org/W1909754239","https://openalex.org/W1963864696","https://openalex.org/W1975299127","https://openalex.org/W1975584136","https://openalex.org/W1978116091","https://openalex.org/W1979423222","https://openalex.org/W1984751884","https://openalex.org/W1993243592","https://openalex.org/W1993280477","https://openalex.org/W1996251228","https://openalex.org/W1997317042","https://openalex.org/W1999131239","https://openalex.org/W2000863793","https://openalex.org/W2007625577","https://openalex.org/W2013994536","https://openalex.org/W2014669590","https://openalex.org/W2017860616","https://openalex.org/W2020584790","https://openalex.org/W2025847301","https://openalex.org/W2026663073","https://openalex.org/W2038013843","https://openalex.org/W2041497115","https://openalex.org/W2046994642","https://openalex.org/W2051254858","https://openalex.org/W2052687631","https://openalex.org/W2052749078","https://openalex.org/W2053033419","https://openalex.org/W2057212851","https://openalex.org/W2060017591","https://openalex.org/W2060333964","https://openalex.org/W2065071837","https://openalex.org/W2072764050","https://openalex.org/W2077640739","https://openalex.org/W2078348590","https://openalex.org/W2081267992","https://openalex.org/W2089126365","https://openalex.org/W2095854818","https://openalex.org/W2110980603","https://openalex.org/W2111199740","https://openalex.org/W2116815924","https://openalex.org/W2123480703","https://openalex.org/W2124597426","https://openalex.org/W2144515939","https://openalex.org/W2151639225","https://openalex.org/W2159422758","https://openalex.org/W2162741904","https://openalex.org/W2165135585","https://openalex.org/W2167775372","https://openalex.org/W2187714930","https://openalex.org/W2257703597","https://openalex.org/W2286150378","https://openalex.org/W2300553253","https://openalex.org/W2400166492","https://openalex.org/W2406149317","https://openalex.org/W2411489146","https://openalex.org/W2412655902","https://openalex.org/W2415430012","https://openalex.org/W2428671231","https://openalex.org/W2434619307"],"related_works":["https://openalex.org/W2415884881","https://openalex.org/W43784428","https://openalex.org/W1999131239","https://openalex.org/W7073863893","https://openalex.org/W2057212851","https://openalex.org/W7098185338","https://openalex.org/W2041569516","https://openalex.org/W2052749078","https://openalex.org/W1992406304","https://openalex.org/W280078261"],"abstract_inverted_index":{"PU.1":[0,66,80,95,160,189,211],"(spi-1),":[1],"a":[2,116],"member":[3],"of":[4,30,32,210],"the":[5,65,93,155,159,167,188,205,214],"Ets":[6],"transcription":[7],"factor":[8],"family,":[9],"is":[10,26,97,127,172],"predominantly":[11],"expressed":[12,174],"in":[13,74,85,103,122,130,133,146,175,180,191],"myeloid":[14,23,75,181,194],"and":[15,22,25,55,78,100,110,124,158,178,183,193],"B":[16,20,104,131,147,168,176,197,206],"cells,":[17,182],"activates":[18,81],"many":[19],"cell":[21,69,76,105,169,198,207],"genes,":[24],"critical":[27],"for":[28,204],"development":[29],"both":[31],"these":[33],"lineages.":[34],"Our":[35],"previous":[36],"studies":[37],"(Chen,":[38],"H.":[39],"M.,":[40],"Ray-Gallet,":[41],"D.,":[42],"Zhang,":[43,51],"P.,":[44],"Hetherington,":[45],"C.":[46],"J.,":[47],"Gonzalez,":[48],"D.":[49,57],"A.,":[50],"D.-E.,":[52],"Moreau-Gachelin,":[53],"F.,":[54],"Tenen,":[56],"G.":[58],"(1995)":[59],"Oncogene":[60],"11,":[61],"1549-1560)":[62],"demonstrate":[63,137],"that":[64,79,92,138,166,184],"promoter":[67,84,96,144,190],"directs":[68],"type-specific":[70],"reporter":[71],"gene":[72],"expression":[73,209],"lines,":[77],"its":[82],"own":[83],"an":[86,149],"autoregulatory":[87,161],"loop.":[88],"Here":[89],"we":[90,164],"show":[91,165],"murine":[94],"also":[98,136],"specifically":[99,114,128],"highly":[101],"functional":[102],"lines":[106],"as":[107],"well.":[108],"Oct-1":[109],"Oct-2":[111],"can":[112,186],"bind":[113],"to":[115,143,154],"site":[117,126,152],"at":[118],"base":[119],"pair":[120],"-55":[121],"vitro,":[123],"this":[125],"protected":[129],"cells":[132,177],"vivo.":[134],"We":[135],"two":[139],"other":[140],"sites":[141],"contribute":[142],"activity":[145],"cells;":[148],"Sp1":[150],"binding":[151],"adjacent":[153],"octamer":[156,215],"site,":[157],"site.":[162,216],"Finally,":[163],"coactivator":[170,200],"OBF-1/Bob1/OCA-B":[171,185],"only":[173],"not":[179],"transactivate":[187],"HeLa":[192],"cells.":[195],"This":[196],"restricted":[199],"may":[201],"be":[202],"responsible":[203],"specific":[208],"mediated":[212],"by":[213]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}