{"id":"https://openalex.org/W2017190459","doi":"https://doi.org/10.1016/0022-4804(70)90079-x","title":"The renal and cardiodynamic effects of prostaglandins (PGE1, PGA1) in renal ischemia","display_name":"The renal and cardiodynamic effects of prostaglandins (PGE1, PGA1) in renal ischemia","publication_year":1970,"publication_date":"1970-11-01","ids":{"openalex":"https://openalex.org/W2017190459","doi":"https://doi.org/10.1016/0022-4804(70)90079-x","mag":"2017190459","pmid":"https://pubmed.ncbi.nlm.nih.gov/5489511"},"language":"en","primary_location":{"id":"doi:10.1016/0022-4804(70)90079-x","doi":"https://doi.org/10.1016/0022-4804(70)90079-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0022-4804(70)90079-x","pdf_url":null,"source":{"id":"https://openalex.org/S45161156","display_name":"Journal of Surgical Research","issn_l":"0022-4804","issn":["0022-4804","1095-8673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110010774","display_name":"Gerald P. Murphy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G.P. Murphy","raw_affiliation_strings":["Roswell Park Memorial Institute, Buffalo, New York 14203 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roswell Park Memorial Institute, Buffalo, New York 14203 USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053630135","display_name":"Viola Hesse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V.E. Hesse","raw_affiliation_strings":["Roswell Park Memorial Institute, Buffalo, New York 14203 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roswell Park Memorial Institute, Buffalo, New York 14203 USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J.L. Evers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.L. Evers","raw_affiliation_strings":["Roswell Park Memorial Institute, Buffalo, New York 14203 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roswell Park Memorial Institute, Buffalo, New York 14203 USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026826601","display_name":"G. H. Hobika","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G. Hobika","raw_affiliation_strings":["Roswell Park Memorial Institute, Buffalo, New York 14203 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roswell Park Memorial Institute, Buffalo, New York 14203 USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110171187","display_name":"JACOBUS W. MOSTERT","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.W. Mostert","raw_affiliation_strings":["Roswell Park Memorial Institute, Buffalo, New York 14203 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roswell Park Memorial Institute, Buffalo, New York 14203 USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051979913","display_name":"A Szolnoky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Szolnoky","raw_affiliation_strings":["Roswell Park Memorial Institute, Buffalo, New York 14203 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roswell Park Memorial Institute, Buffalo, New York 14203 USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029154714","display_name":"Rikus Schoonees","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Schoonees","raw_affiliation_strings":["Roswell Park Memorial Institute, Buffalo, New York 14203 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roswell Park Memorial Institute, Buffalo, New York 14203 USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033723340","display_name":"J. Abramczyk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Abramczyk","raw_affiliation_strings":["Roswell Park Memorial Institute, Buffalo, New York 14203 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roswell Park Memorial Institute, Buffalo, New York 14203 USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110902013","display_name":"J. T. Grace","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.T. Grace","raw_affiliation_strings":["Roswell Park Memorial Institute, Buffalo, New York 14203 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roswell Park Memorial Institute, Buffalo, New York 14203 USA","institution_ids":["https://openalex.org/I1292894508"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1292894508"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":null,"fwci":5.6342,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.95144399,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"10","issue":"11","first_page":"533","last_page":"541"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.5727999806404114,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.5727999806404114,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12910","display_name":"Eicosanoids and Hypertension Pharmacology","score":0.16169999539852142,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.13089999556541443,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostaglandins","display_name":"prostaglandins","score":0.9779999852180481},{"id":"https://openalex.org/keywords/prostaglandin-e1","display_name":"prostaglandin E1","score":0.9399999976158142},{"id":"https://openalex.org/keywords/prostaglandin-a1","display_name":"prostaglandin A1","score":0.9919999837875366},{"id":"https://openalex.org/keywords/renal-ischemia","display_name":"renal ischemia","score":0.9909999966621399},{"id":"https://openalex.org/keywords/renal-blood-flow","display_name":"renal blood flow","score":0.6669999957084656},{"id":"https://openalex.org/keywords/cardiac-effects","display_name":"cardiac effects","score":0.5659999847412109},{"id":"https://openalex.org/keywords/vasodilation","display_name":"vasodilation","score":0.527999997138977}],"concepts":[{"id":"https://openalex.org/C2780721119","wikidata":"https://www.wikidata.org/wiki/Q7312492","display_name":"Renal ischemia","level":4,"score":0.6279661655426025},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.51163250207901},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.45670151710510254},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.36527448892593384},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3505568504333496},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3299618065357208},{"id":"https://openalex.org/C2780114680","wikidata":"https://www.wikidata.org/wiki/Q1413991","display_name":"Reperfusion injury","level":3,"score":0.05272167921066284}],"mesh":[{"descriptor_ui":"D000618","descriptor_name":"Aminohippuric Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003404","descriptor_name":"Creatinine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005919","descriptor_name":"Glomerular Filtration Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006977","descriptor_name":"Hypertension, Renal","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D007444","descriptor_name":"Inulin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007511","descriptor_name":"Ischemia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009318","descriptor_name":"Natriuresis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011453","descriptor_name":"Prostaglandins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D012039","descriptor_name":"Regional Blood Flow","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012078","descriptor_name":"Renal Artery Obstruction","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D013268","descriptor_name":"Stimulation, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0022-4804(70)90079-x","doi":"https://doi.org/10.1016/0022-4804(70)90079-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0022-4804(70)90079-x","pdf_url":null,"source":{"id":"https://openalex.org/S45161156","display_name":"Journal of Surgical Research","issn_l":"0022-4804","issn":["0022-4804","1095-8673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Research","raw_type":"journal-article"},{"id":"pmid:5489511","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5489511","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of surgical research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":5,"referenced_works":["https://openalex.org/W1996083516","https://openalex.org/W2142584844","https://openalex.org/W2411128342","https://openalex.org/W2411907620","https://openalex.org/W2417497627"],"related_works":["https://openalex.org/W2094339866","https://openalex.org/W4253141333","https://openalex.org/W2414077578","https://openalex.org/W3101566214","https://openalex.org/W3139529906","https://openalex.org/W2411832208","https://openalex.org/W4233399958","https://openalex.org/W2464166376","https://openalex.org/W2572809016","https://openalex.org/W2406138332"],"abstract_inverted_index":null,"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}