{"id":"https://openalex.org/W2017180228","doi":"https://doi.org/10.1177/0363546511420819","title":"Treatment Outcomes of Alginate-Embedded Allogenic Mesenchymal Stem Cells Versus Autologous Chondrocytes for the Repair of Focal Articular Cartilage Defects in a Rabbit Model","display_name":"Treatment Outcomes of Alginate-Embedded Allogenic Mesenchymal Stem Cells Versus Autologous Chondrocytes for the Repair of Focal Articular Cartilage Defects in a Rabbit Model","publication_year":2011,"publication_date":"2011-09-13","ids":{"openalex":"https://openalex.org/W2017180228","doi":"https://doi.org/10.1177/0363546511420819","mag":"2017180228","pmid":"https://pubmed.ncbi.nlm.nih.gov/21917609"},"language":"en","primary_location":{"id":"doi:10.1177/0363546511420819","doi":"https://doi.org/10.1177/0363546511420819","is_oa":false,"landing_page_url":"https://doi.org/10.1177/0363546511420819","pdf_url":null,"source":{"id":"https://openalex.org/S154904565","display_name":"The American Journal of Sports Medicine","issn_l":"0363-5465","issn":["0363-5465","1552-3365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Sports Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086049173","display_name":"Liang Xin Tay","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Liang Xin Tay","raw_affiliation_strings":["Tissue Engineering Group, NOCERAL, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia","Tissue Engineering Group, National Orthopaedic Surgery Centre of Excellence for Research and Learning (NOCERAL), Department of Orthopaedic Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. liangxin28@gmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tissue Engineering Group, NOCERAL, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I33849332"]},{"raw_affiliation_string":"Tissue Engineering Group, National Orthopaedic Surgery Centre of Excellence for Research and Learning (NOCERAL), Department of Orthopaedic Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. liangxin28@gmail.com","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066371582","display_name":"Raja Elina Ahmad","orcid":"https://orcid.org/0000-0001-8048-4217","observed_orcids":["https://orcid.org/0000-0001-8048-4217"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Raja Elina Ahmad","raw_affiliation_strings":["Department of Physiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063773365","display_name":"Havva Dashtdar","orcid":"https://orcid.org/0000-0002-5797-1540","observed_orcids":["https://orcid.org/0000-0002-5797-1540"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Havva Dashtdar","raw_affiliation_strings":["Tissue Engineering Group, NOCERAL, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tissue Engineering Group, NOCERAL, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016289625","display_name":"KK Tay","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"K.W. Tay","raw_affiliation_strings":["Tissue Engineering Group, NOCERAL, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tissue Engineering Group, NOCERAL, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027040852","display_name":"T. Masjuddin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"T. Masjuddin","raw_affiliation_strings":["Tissue Engineering Group, NOCERAL, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tissue Engineering Group, NOCERAL, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011682303","display_name":"Sharaniza Ab Rahim","orcid":"https://orcid.org/0000-0003-4502-3559","observed_orcids":["https://orcid.org/0000-0003-4502-3559"]},"institutions":[{"id":"https://openalex.org/I4210138650","display_name":"Universiti Teknologi MARA System","ror":"https://ror.org/030847t23","country_code":"MY","type":"education","lineage":["https://openalex.org/I4210138650","https://openalex.org/I82724352"]},{"id":"https://openalex.org/I82724352","display_name":"Universiti Teknologi MARA","ror":"https://ror.org/05n8tts92","country_code":"MY","type":"education","lineage":["https://openalex.org/I82724352"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"S. Ab-Rahim","raw_affiliation_strings":["Faculty of Medicine, UiTM, Shah Alam, Selangor, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, UiTM, Shah Alam, Selangor, Malaysia","institution_ids":["https://openalex.org/I4210138650","https://openalex.org/I82724352"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026906324","display_name":"Pan Pan Chong","orcid":"https://orcid.org/0000-0003-1893-8091","observed_orcids":["https://orcid.org/0000-0003-1893-8091"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Pan Pan Chong","raw_affiliation_strings":["Tissue Engineering Group, NOCERAL, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tissue Engineering Group, NOCERAL, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004359582","display_name":"Lakshmi Selvaratnam","orcid":"https://orcid.org/0000-0002-2147-1616","observed_orcids":["https://orcid.org/0000-0002-2147-1616"]},"institutions":[{"id":"https://openalex.org/I11662577","display_name":"Monash University Malaysia","ror":"https://ror.org/00yncr324","country_code":"MY","type":"education","lineage":["https://openalex.org/I11662577","https://openalex.org/I56590836"]},{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU","MY"],"is_corresponding":false,"raw_author_name":"L. Selvaratnam","raw_affiliation_strings":["School of Medicine and Health Sciences, Monash University, Sunway Campus, Selangor, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine and Health Sciences, Monash University, Sunway Campus, Selangor, Malaysia","institution_ids":["https://openalex.org/I11662577","https://openalex.org/I56590836"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034713922","display_name":"Tunku Kamarul","orcid":"https://orcid.org/0000-0002-6028-1313","observed_orcids":["https://orcid.org/0000-0002-6028-1313"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"T. Kamarul","raw_affiliation_strings":["Tissue Engineering Group, NOCERAL, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tissue Engineering Group, NOCERAL, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4400,"currency":"USD","value_usd":4400},"apc_paid":null,"fwci":5.5606,"has_fulltext":false,"cited_by_count":91,"citation_normalized_percentile":{"value":0.95823169,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"40","issue":"1","first_page":"83","last_page":"90"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.008899999782443047,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/autologous-chondrocytes","display_name":"autologous chondrocytes","score":0.9309999942779541},{"id":"https://openalex.org/keywords/articular-cartilage-defects","display_name":"articular cartilage defects","score":0.8109999895095825},{"id":"https://openalex.org/keywords/cartilage-repair","display_name":"cartilage repair","score":0.7799999713897705},{"id":"https://openalex.org/keywords/allogeneic-cell-therapy","display_name":"allogeneic cell therapy","score":0.6660000085830688},{"id":"https://openalex.org/keywords/chondrogenesis","display_name":"chondrogenesis","score":0.8119999766349792},{"id":"https://openalex.org/keywords/glycosaminoglycans","display_name":"glycosaminoglycans","score":0.8669999837875366},{"id":"https://openalex.org/keywords/rabbit-model","display_name":"rabbit model","score":0.6909999847412109},{"id":"https://openalex.org/keywords/full-thickness-cartilage-defects","display_name":"full-thickness cartilage defects","score":0.7419999837875366}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8471590876579285},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.812411367893219},{"id":"https://openalex.org/C35496256","wikidata":"https://www.wikidata.org/wiki/Q5104524","display_name":"Chondrogenesis","level":3,"score":0.7768858671188354},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.751662015914917},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.6450285911560059},{"id":"https://openalex.org/C2777564180","wikidata":"https://www.wikidata.org/wiki/Q3109230","display_name":"Articular cartilage repair","level":5,"score":0.5873510241508484},{"id":"https://openalex.org/C2781403057","wikidata":"https://www.wikidata.org/wiki/Q775480","display_name":"Chondrocyte","level":3,"score":0.5573136210441589},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.4788384437561035},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.43928924202919006},{"id":"https://openalex.org/C2777870964","wikidata":"https://www.wikidata.org/wiki/Q787050","display_name":"Autologous chondrocyte implantation","level":5,"score":0.42674148082733154},{"id":"https://openalex.org/C153074725","wikidata":"https://www.wikidata.org/wiki/Q407553","display_name":"Glycosaminoglycan","level":2,"score":0.42387300729751587},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.4138081669807434},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.39265769720077515},{"id":"https://openalex.org/C3020332539","wikidata":"https://www.wikidata.org/wiki/Q2014564","display_name":"Articular cartilage","level":4,"score":0.37182489037513733},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.30588945746421814},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07093450427055359},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.06753036379814148},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000464","descriptor_name":"Alginates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002358","descriptor_name":"Cartilage, Articular","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":true},{"descriptor_ui":"D002358","descriptor_name":"Cartilage, Articular","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006025","descriptor_name":"Glycosaminoglycans","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007124","descriptor_name":"Immunoenzyme Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007718","descriptor_name":"Knee Injuries","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014182","descriptor_name":"Transplantation, Autologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014184","descriptor_name":"Transplantation, Homologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019902","descriptor_name":"Chondrocytes","qualifier_ui":"Q000637","qualifier_name":"transplantation","is_major_topic":true},{"descriptor_ui":"D045164","descriptor_name":"Mesenchymal Stem Cell Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1177/0363546511420819","doi":"https://doi.org/10.1177/0363546511420819","is_oa":false,"landing_page_url":"https://doi.org/10.1177/0363546511420819","pdf_url":null,"source":{"id":"https://openalex.org/S154904565","display_name":"The American Journal of Sports Medicine","issn_l":"0363-5465","issn":["0363-5465","1552-3365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Sports Medicine","raw_type":"journal-article"},{"id":"pmid:21917609","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21917609","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of sports medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W320698679","https://openalex.org/W1482530399","https://openalex.org/W1508246447","https://openalex.org/W1522229466","https://openalex.org/W1569612555","https://openalex.org/W1892871548","https://openalex.org/W1964895653","https://openalex.org/W1965387344","https://openalex.org/W1966262538","https://openalex.org/W1976103435","https://openalex.org/W1978035620","https://openalex.org/W1978640618","https://openalex.org/W1988592246","https://openalex.org/W1991146769","https://openalex.org/W1996803044","https://openalex.org/W1998112612","https://openalex.org/W2007897934","https://openalex.org/W2014988196","https://openalex.org/W2016363042","https://openalex.org/W2035209595","https://openalex.org/W2039488563","https://openalex.org/W2042668077","https://openalex.org/W2046243793","https://openalex.org/W2047531782","https://openalex.org/W2047627233","https://openalex.org/W2062549368","https://openalex.org/W2063742493","https://openalex.org/W2070435400","https://openalex.org/W2070698616","https://openalex.org/W2072589827","https://openalex.org/W2077008849","https://openalex.org/W2079191512","https://openalex.org/W2082690970","https://openalex.org/W2084771933","https://openalex.org/W2087578260","https://openalex.org/W2091464294","https://openalex.org/W2095223128","https://openalex.org/W2100994995","https://openalex.org/W2102488850","https://openalex.org/W2104820755","https://openalex.org/W2105159857","https://openalex.org/W2108725095","https://openalex.org/W2116417514","https://openalex.org/W2117957511","https://openalex.org/W2125050513","https://openalex.org/W2132590692","https://openalex.org/W2142400618","https://openalex.org/W2149790590","https://openalex.org/W2154757527","https://openalex.org/W2159417266","https://openalex.org/W2159999899","https://openalex.org/W2163211541","https://openalex.org/W2187684329","https://openalex.org/W2236789517","https://openalex.org/W2413041650"],"related_works":["https://openalex.org/W2142400618","https://openalex.org/W2060304299","https://openalex.org/W2606452453","https://openalex.org/W2363779552","https://openalex.org/W2504228461","https://openalex.org/W4384469828","https://openalex.org/W2997360381","https://openalex.org/W2946787795","https://openalex.org/W2035334292","https://openalex.org/W2070084144"],"abstract_inverted_index":{"BACKGROUND:":[0],"Mesenchymal":[1],"stem":[2],"cells":[3],"(MSCs)":[4],"represent":[5],"a":[6,33],"promising":[7],"alternative":[8],"form":[9],"of":[10,19,35,40,50,76,97,105,154,172,238,260,265,277],"cell-based":[11],"therapy":[12],"for":[13,21,48,74,152,236,267],"cartilage":[14,52,66,79,89,155,208,240,268],"injury.":[15],"However,":[16],"the":[17,38,94,98,116,120,137,160,186,194,218,262],"capacity":[18],"MSCs":[20,41,61,266],"chondrogenesis":[22],"has":[23],"not":[24],"been":[25],"fully":[26],"explored.":[27],"In":[28],"particular,":[29],"there":[30],"is":[31],"presently":[32],"lack":[34],"studies":[36],"comparing":[37],"effectiveness":[39,233],"to":[42],"conventional":[43,291],"autologous":[44],"chondrocyte":[45],"(autoC)":[46],"treatment":[47,151,188,196,219],"regeneration":[49,68,248],"full-thickness":[51],"defects":[53,90],"in":[54,64,102,185,217,245,275],"vivo.":[55],"HYPOTHESIS:":[56],"Treatment":[57],"with":[58,72,125,222,250,290],"allogenic":[59],"undifferentiated":[60],"(alloMSCs)":[62],"results":[63,256],"superior":[65,246],"tissue":[67,156,247],"profiles":[69],"when":[70],"compared":[71,221,249,289],"autoC":[73,132,195,235,292],"repair":[75,237,269],"focal":[77,239],"articular":[78,88],"defects.":[80,241,252],"STUDY":[81],"DESIGN:":[82],"Controlled":[83],"laboratory":[84],"study.":[85],"METHODS:":[86],"Full-thickness":[87],"were":[91,145,214],"created":[92],"on":[93],"weightbearing":[95],"surface":[96],"medial":[99],"femoral":[100],"condyles":[101],"both":[103,204],"knees":[104],"New":[106],"Zealand":[107],"White":[108],"rabbits":[109,144],"(N":[110],"=":[111,129,134,202],"30).":[112],"Six":[113],"weeks":[114],"after":[115,150,270],"defect":[117],"was":[118,123],"induced,":[119],"right":[121],"knee":[122,139],"treated":[124],"either":[126],"alloMSCs":[127],"(n":[128,133],"12)":[130],"or":[131,273],"18),":[135],"while":[136],"left":[138],"remained":[140],"untreated":[141,251],"(control).":[142],"The":[143,255],"sacrificed":[146],"at":[147],"6":[148],"months":[149],"assessment":[153],"regeneration,":[157],"which":[158],"included":[159],"Brittberg":[161,183],"morphologic":[162],"score,":[163,168],"histologic":[164],"grading":[165],"by":[166],"O'Driscoll":[167],"and":[169,284],"quantitative":[170],"analysis":[171],"glycosaminoglycans":[173],"per":[174],"total":[175],"protein":[176],"content.":[177],"RESULTS:":[178],"Apart":[179],"from":[180],"significantly":[181,215],"higher":[182,216],"scores":[184],"alloMSC":[187],"group":[189,197],"(8.8":[190],"\u00b1":[191,199],"0.8)":[192,200],"versus":[193],"(6.6":[198],"(P":[201,226],".04),":[203],"treatments":[205,243],"showed":[206],"similar":[207,232,278],"regenerative":[209],"profiles.":[210],"All":[211],"outcome":[212],"measures":[213],"groups":[220],"their":[223],"respective":[224],"controls":[225],"<":[227],".05).":[228],"CONCLUSION:":[229],"AlloMSCs":[230],"have":[231,257],"as":[234,288],"Both":[242],"resulted":[244],"CLINICAL":[253],"RELEVANCE:":[254],"an":[258],"implication":[259],"supporting":[261],"potential":[263,285],"use":[264],"sports":[271],"injuries":[272],"diseases,":[274],"view":[276],"efficacy":[279],"but":[280],"less":[281],"patient":[282],"morbidity":[283],"cost":[286],"savings":[287],"therapy.":[293]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":13},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2016-06-24T00:00:00"}