{"id":"https://openalex.org/W2017155776","doi":"https://doi.org/10.1016/0378-4274(83)90117-0","title":"Absorption and elimination of a branched-chain alkylpolyethoxylate surfactant in rats","display_name":"Absorption and elimination of a branched-chain alkylpolyethoxylate surfactant in rats","publication_year":1983,"publication_date":"1983-09-01","ids":{"openalex":"https://openalex.org/W2017155776","doi":"https://doi.org/10.1016/0378-4274(83)90117-0","mag":"2017155776","pmid":"https://pubmed.ncbi.nlm.nih.gov/6665809"},"language":"en","primary_location":{"id":"doi:10.1016/0378-4274(83)90117-0","doi":"https://doi.org/10.1016/0378-4274(83)90117-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0378-4274(83)90117-0","pdf_url":null,"source":{"id":"https://openalex.org/S205878144","display_name":"Toxicology Letters","issn_l":"0378-4274","issn":["0378-4274","1879-3169"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023766828","display_name":"George Calvin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114316","display_name":"Procter & Gamble (Belgium)","ror":"https://ror.org/027f7xa47","country_code":"BE","type":"company","lineage":["https://openalex.org/I4210114316","https://openalex.org/I74680897"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"G. Calvin","raw_affiliation_strings":["Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, PE18 6ES U.K","Procter and Gamble, European Technical Centre, Temselaan 100, B-1820-Strombeek-Bever, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, PE18 6ES U.K","institution_ids":[]},{"raw_affiliation_string":"Procter and Gamble, European Technical Centre, Temselaan 100, B-1820-Strombeek-Bever, Belgium","institution_ids":["https://openalex.org/I4210114316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110074265","display_name":"Leslie F. Chasseaud","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L.F. Chasseaud","raw_affiliation_strings":["Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, PE18 6ES U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, PE18 6ES U.K","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082898288","display_name":"William H. Down","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W.H. Down","raw_affiliation_strings":["Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, PE18 6ES U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, PE18 6ES U.K","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046909172","display_name":"Stephen A. Ballard","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S.A. Ballard","raw_affiliation_strings":["Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, PE18 6ES U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, PE18 6ES U.K","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103051075","display_name":"D. R. Hawkins","orcid":"https://orcid.org/0009-0002-3920-4230","observed_orcids":["https://orcid.org/0009-0002-3920-4230"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D.R. Hawkins","raw_affiliation_strings":["Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, PE18 6ES U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, PE18 6ES U.K","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4270,"currency":"USD","value_usd":4270},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.13811781,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"18","issue":"3","first_page":"351","last_page":"357"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13092","display_name":"Environmental Chemistry and Analysis","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13092","display_name":"Environmental Chemistry and Analysis","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10721","display_name":"Surfactants and Colloidal Systems","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/surfactants","display_name":"surfactants","score":0.8149999976158142},{"id":"https://openalex.org/keywords/absorption","display_name":"absorption","score":0.47200000286102295},{"id":"https://openalex.org/keywords/elimination","display_name":"elimination","score":0.8270000219345093},{"id":"https://openalex.org/keywords/biotransformation","display_name":"biotransformation","score":0.8500000238418579},{"id":"https://openalex.org/keywords/enterohepatic-circulation","display_name":"enterohepatic circulation","score":0.949999988079071},{"id":"https://openalex.org/keywords/urinary-excretion","display_name":"urinary excretion","score":0.6159999966621399},{"id":"https://openalex.org/keywords/fecal-excretion","display_name":"fecal excretion","score":0.9459999799728394},{"id":"https://openalex.org/keywords/skin-absorption","display_name":"percutaneous absorption","score":0.7919999957084656},{"id":"https://openalex.org/keywords/oral-administration","display_name":"oral administration","score":0.5239999890327454},{"id":"https://openalex.org/keywords/14c-labeled-compounds","display_name":"14C-labeled compounds","score":0.7400000095367432},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.48399999737739563}],"concepts":[{"id":"https://openalex.org/C2778620825","wikidata":"https://www.wikidata.org/wiki/Q1344633","display_name":"Enterohepatic circulation","level":3,"score":0.9369957447052002},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.7330834269523621},{"id":"https://openalex.org/C2777288759","wikidata":"https://www.wikidata.org/wiki/Q4164182","display_name":"Dosing","level":2,"score":0.72479647397995},{"id":"https://openalex.org/C125287762","wikidata":"https://www.wikidata.org/wiki/Q1758948","display_name":"Absorption (acoustics)","level":2,"score":0.6829800605773926},{"id":"https://openalex.org/C2780512811","wikidata":"https://www.wikidata.org/wiki/Q11829360","display_name":"Gastrointestinal tract","level":2,"score":0.6372878551483154},{"id":"https://openalex.org/C61716771","wikidata":"https://www.wikidata.org/wiki/Q496","display_name":"Feces","level":2,"score":0.5970550775527954},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5883383750915527},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.41382595896720886},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3682304322719574},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.36417824029922485},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3445877432823181},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3438211679458618},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2042313814163208},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16039374470710754},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1259746253490448},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000042","descriptor_name":"Absorption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000287","descriptor_name":"Administration, Topical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001711","descriptor_name":"Biotransformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011092","descriptor_name":"Polyethylene Glycols","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D011092","descriptor_name":"Polyethylene Glycols","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013501","descriptor_name":"Surface-Active Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D013501","descriptor_name":"Surface-Active Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0378-4274(83)90117-0","doi":"https://doi.org/10.1016/0378-4274(83)90117-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0378-4274(83)90117-0","pdf_url":null,"source":{"id":"https://openalex.org/S205878144","display_name":"Toxicology Letters","issn_l":"0378-4274","issn":["0378-4274","1879-3169"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology Letters","raw_type":"journal-article"},{"id":"pmid:6665809","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6665809","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W1575580604","https://openalex.org/W2054191774","https://openalex.org/W2054693391","https://openalex.org/W2407197960"],"related_works":["https://openalex.org/W2054693391","https://openalex.org/W2100531215","https://openalex.org/W2158324764","https://openalex.org/W2072114038","https://openalex.org/W4255283556","https://openalex.org/W2331260329","https://openalex.org/W2042766851","https://openalex.org/W2419655766","https://openalex.org/W2112954149","https://openalex.org/W2142107163"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}