{"id":"https://openalex.org/W2017119083","doi":"https://doi.org/10.1101/sqb.1987.052.01.005","title":"Which Organic Compounds Could Have Occurred on the Prebiotic Earth?","display_name":"Which Organic Compounds Could Have Occurred on the Prebiotic Earth?","publication_year":1987,"publication_date":"1987-01-01","ids":{"openalex":"https://openalex.org/W2017119083","doi":"https://doi.org/10.1101/sqb.1987.052.01.005","mag":"2017119083","pmid":"https://pubmed.ncbi.nlm.nih.gov/3454260"},"language":"en","primary_location":{"id":"doi:10.1101/sqb.1987.052.01.005","doi":"https://doi.org/10.1101/sqb.1987.052.01.005","is_oa":false,"landing_page_url":"https://doi.org/10.1101/sqb.1987.052.01.005","pdf_url":null,"source":{"id":"https://openalex.org/S78756772","display_name":"Cold Spring Harbor Symposia on Quantitative Biology","issn_l":"0091-7451","issn":["0091-7451","1943-4456"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harbor Symposia on Quantitative Biology","raw_type":"journal-article"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109193823","display_name":"Stanley Lloyd Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"S.L. Miller","raw_affiliation_strings":["Department of Chemistry, University of California, San Diego, La Jolla 90293"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of California, San Diego, La Jolla 90293","institution_ids":["https://openalex.org/I36258959"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5109193823"],"corresponding_institution_ids":["https://openalex.org/I36258959"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":181,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"52","issue":"0","first_page":"17","last_page":"27"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11445","display_name":"Origins and Evolution of Life","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11445","display_name":"Origins and Evolution of Life","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10109","display_name":"Paleontology and Stratigraphy of Fossils","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1911","display_name":"Paleontology"},"field":{"id":"https://openalex.org/fields/19","display_name":"Earth and Planetary Sciences"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prebiotic-chemistry","display_name":"prebiotic chemistry","score":0.8539999723434448},{"id":"https://openalex.org/keywords/origin-of-life","display_name":"origin of life","score":0.9679999947547913},{"id":"https://openalex.org/keywords/organic-synthesis","display_name":"organic synthesis","score":0.6700000166893005},{"id":"https://openalex.org/keywords/miller-urey-experiment","display_name":"Miller-Urey experiment","score":0.7089999914169312},{"id":"https://openalex.org/keywords/early-earth","display_name":"early Earth","score":0.5809999704360962},{"id":"https://openalex.org/keywords/nucleotides","display_name":"nucleotides","score":0.5080000162124634}],"concepts":[{"id":"https://openalex.org/C26148502","wikidata":"https://www.wikidata.org/wiki/Q2488752","display_name":"Earth (classical element)","level":2,"score":0.7230809330940247},{"id":"https://openalex.org/C87355193","wikidata":"https://www.wikidata.org/wiki/Q411","display_name":"Astrobiology","level":1,"score":0.6394680738449097},{"id":"https://openalex.org/C136197465","wikidata":"https://www.wikidata.org/wiki/Q1729295","display_name":"Variety (cybernetics)","level":2,"score":0.5603557825088501},{"id":"https://openalex.org/C2775980262","wikidata":"https://www.wikidata.org/wiki/Q218870","display_name":"Prebiotic","level":2,"score":0.4213530123233795},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.40036648511886597},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3557731509208679},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31295061111450195},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.23906561732292175},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.18814736604690552},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12179639935493469},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.10591626167297363},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.07992705702781677},{"id":"https://openalex.org/C37914503","wikidata":"https://www.wikidata.org/wiki/Q156495","display_name":"Mathematical physics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069497","descriptor_name":"Origin of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002384","descriptor_name":"Catalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011687","descriptor_name":"Purines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011743","descriptor_name":"Pyrimidines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011830","descriptor_name":"Radiation Effects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1101/sqb.1987.052.01.005","doi":"https://doi.org/10.1101/sqb.1987.052.01.005","is_oa":false,"landing_page_url":"https://doi.org/10.1101/sqb.1987.052.01.005","pdf_url":null,"source":{"id":"https://openalex.org/S78756772","display_name":"Cold Spring Harbor Symposia on Quantitative Biology","issn_l":"0091-7451","issn":["0091-7451","1943-4456"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harbor Symposia on Quantitative Biology","raw_type":"journal-article"},{"id":"pmid:3454260","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3454260","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harbor symposia on quantitative biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306101","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1914006297","https://openalex.org/W1554468636","https://openalex.org/W1986393531","https://openalex.org/W2128130474","https://openalex.org/W1577953233","https://openalex.org/W4295793781","https://openalex.org/W4236543694","https://openalex.org/W1642935671","https://openalex.org/W2624782051","https://openalex.org/W2334169772"],"abstract_inverted_index":{"In":[0],"the":[1,17,29,42,57],"past":[2],"three":[3],"decades,":[4],"a":[5,62],"wide":[6],"variety":[7],"of":[8,44,64],"experiments":[9],"have":[10],"been":[11],"designed":[12],"to":[13,21,52,61],"simulate":[14],"conditions":[15],"on":[16],"primitive":[18],"earth":[19],"and":[20,40,56,69,73],"demonstrate":[22],"how":[23],"organic":[24],"compounds":[25],"that":[26],"made":[27],"up":[28],"first":[30],"living":[31],"organisms":[32],"were":[33],"synthesized.":[34],"This":[35],"paper":[36],"reviews":[37],"this":[38],"work":[39],"indicates":[41],"status":[43],"such":[45],"syntheses.":[46],"There":[47],"is":[48,59],"too":[49],"much":[50],"material":[51],"review":[53],"in":[54],"detail,":[55],"reader":[58],"directed":[60],"number":[63],"more":[65],"complete":[66],"discussions":[67],"(Miller":[68],"Orgel":[70],"1974;":[71],"Kenyon":[72],"Steinman":[74],"1969;":[75],"Lemmon":[76],"1970).":[77]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":6},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}