{"id":"https://openalex.org/W2017105319","doi":"https://doi.org/10.1007/s10072-010-0264-y","title":"Pathophysiology of migraine chronification","display_name":"Pathophysiology of migraine chronification","publication_year":2010,"publication_date":"2010-05-12","ids":{"openalex":"https://openalex.org/W2017105319","doi":"https://doi.org/10.1007/s10072-010-0264-y","mag":"2017105319","pmid":"https://pubmed.ncbi.nlm.nih.gov/20464576"},"language":"en","primary_location":{"id":"doi:10.1007/s10072-010-0264-y","doi":"https://doi.org/10.1007/s10072-010-0264-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10072-010-0264-y","pdf_url":null,"source":{"id":"https://openalex.org/S75480959","display_name":"Neurological Sciences","issn_l":"1590-1874","issn":["1590-1874","1590-3478"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurological Sciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055793459","display_name":"Marco Aguggia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111911","display_name":"Azienda Sanitaria Locale di Asti","ror":"https://ror.org/019z87133","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210111911"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"M. Aguggia","raw_affiliation_strings":["Neurological Department, Cardinal Massaia Hospital, Via Conte Verde 215, 14100, Asti, Italy. aguggiamarco@tiscali.it","Cardinal Massaia Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurological Department, Cardinal Massaia Hospital, Via Conte Verde 215, 14100, Asti, Italy. aguggiamarco@tiscali.it","institution_ids":["https://openalex.org/I4210111911"]},{"raw_affiliation_string":"Cardinal Massaia Hospital","institution_ids":["https://openalex.org/I4210111911"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038597830","display_name":"Maria Gabriella Saracco","orcid":"https://orcid.org/0000-0001-5641-9079","observed_orcids":["https://orcid.org/0000-0001-5641-9079"]},"institutions":[{"id":"https://openalex.org/I4210111911","display_name":"Azienda Sanitaria Locale di Asti","ror":"https://ror.org/019z87133","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210111911"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. G. Saracco","raw_affiliation_strings":["Neurological Department, Cardinal Massaia Hospital, Via Conte Verde 215, 14100, Asti, Italy","Cardinal Massaia Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurological Department, Cardinal Massaia Hospital, Via Conte Verde 215, 14100, Asti, Italy","institution_ids":["https://openalex.org/I4210111911"]},{"raw_affiliation_string":"Cardinal Massaia Hospital","institution_ids":["https://openalex.org/I4210111911"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5055793459"],"corresponding_institution_ids":["https://openalex.org/I4210111911"],"apc_list":{"value":4090,"currency":"USD","value_usd":4090},"apc_paid":null,"fwci":0.4575,"has_fulltext":false,"cited_by_count":35,"citation_normalized_percentile":{"value":0.37122002,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"31","issue":"S1","first_page":"15","last_page":"17"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10498","display_name":"Migraine and Headache Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10498","display_name":"Migraine and Headache Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10852","display_name":"Temporomandibular Joint Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/migraine","display_name":"migraine","score":0.8629999756813049},{"id":"https://openalex.org/keywords/migraine-chronification","display_name":"migraine chronification","score":0.8519999980926514},{"id":"https://openalex.org/keywords/pathophysiology","display_name":"pathophysiology","score":0.921999990940094},{"id":"https://openalex.org/keywords/migraine-progression","display_name":"migraine progression","score":0.5239999890327454},{"id":"https://openalex.org/keywords/attack-frequency","display_name":"attack frequency","score":0.47200000286102295},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8309999704360962},{"id":"https://openalex.org/keywords/medication-overuse","display_name":"medication overuse","score":0.9259999990463257},{"id":"https://openalex.org/keywords/stressful-life-events","display_name":"life events","score":0.8619999885559082},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sleep-disturbance","display_name":"sleep disorders","score":1.0},{"id":"https://openalex.org/keywords/cutaneous-allodynia","display_name":"cutaneous allodynia","score":0.9150000214576721},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.7570000290870667}],"concepts":[{"id":"https://openalex.org/C2778541695","wikidata":"https://www.wikidata.org/wiki/Q133823","display_name":"Migraine","level":2,"score":0.8528081774711609},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.799686074256897},{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.7329822778701782},{"id":"https://openalex.org/C2910587157","wikidata":"https://www.wikidata.org/wiki/Q133823","display_name":"Chronic Migraine","level":3,"score":0.5962345600128174},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.577907383441925},{"id":"https://openalex.org/C12770488","wikidata":"https://www.wikidata.org/wiki/Q188449","display_name":"Neurosurgery","level":2,"score":0.5434709787368774},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5361940860748291},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.5251626372337341},{"id":"https://openalex.org/C2777883359","wikidata":"https://www.wikidata.org/wiki/Q1888634","display_name":"Allodynia","level":5,"score":0.482187420129776},{"id":"https://openalex.org/C2779889316","wikidata":"https://www.wikidata.org/wiki/Q642836","display_name":"Neuroradiology","level":3,"score":0.4696808457374573},{"id":"https://openalex.org/C2777350023","wikidata":"https://www.wikidata.org/wiki/Q1154226","display_name":"Aura","level":3,"score":0.4231695830821991},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.37467920780181885},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24543792009353638},{"id":"https://openalex.org/C2779245659","wikidata":"https://www.wikidata.org/wiki/Q1633866","display_name":"Hyperalgesia","level":4,"score":0.1310892403125763},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C15490471","wikidata":"https://www.wikidata.org/wiki/Q2734305","display_name":"Nociception","level":3,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002908","descriptor_name":"Chronic Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008881","descriptor_name":"Migraine Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D008881","descriptor_name":"Migraine Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10072-010-0264-y","doi":"https://doi.org/10.1007/s10072-010-0264-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10072-010-0264-y","pdf_url":null,"source":{"id":"https://openalex.org/S75480959","display_name":"Neurological Sciences","issn_l":"1590-1874","issn":["1590-1874","1590-3478"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurological Sciences","raw_type":"journal-article"},{"id":"pmid:20464576","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20464576","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W193516327","https://openalex.org/W1581399947","https://openalex.org/W1586995597","https://openalex.org/W1607858133","https://openalex.org/W1968865115","https://openalex.org/W1983127516","https://openalex.org/W1986358138","https://openalex.org/W1991073019","https://openalex.org/W2004057280","https://openalex.org/W2012606705","https://openalex.org/W2015519386","https://openalex.org/W2019251423","https://openalex.org/W2022759950","https://openalex.org/W2027939851","https://openalex.org/W2040792219","https://openalex.org/W2047455969","https://openalex.org/W2052258972","https://openalex.org/W2052524410","https://openalex.org/W2060416301","https://openalex.org/W2060600545","https://openalex.org/W2081624583","https://openalex.org/W2082095188","https://openalex.org/W2087196799","https://openalex.org/W2087866106","https://openalex.org/W2097107346","https://openalex.org/W2098351223","https://openalex.org/W2108715831","https://openalex.org/W2122836206","https://openalex.org/W2150027687","https://openalex.org/W2157233057","https://openalex.org/W2166963276","https://openalex.org/W2167004463","https://openalex.org/W2994536360"],"related_works":["https://openalex.org/W2463900009","https://openalex.org/W7216901682","https://openalex.org/W1575554606","https://openalex.org/W7222779313","https://openalex.org/W1547554586","https://openalex.org/W1967283651","https://openalex.org/W2327138304","https://openalex.org/W1974076909","https://openalex.org/W2065158904","https://openalex.org/W188487094"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}