{"id":"https://openalex.org/W2017102736","doi":"https://doi.org/10.1080/15287398309530423","title":"The acute toxicity of penta\u2010, hexa\u2010, and heptachlorohydroxydiphenyl ethers in mice","display_name":"The acute toxicity of penta\u2010, hexa\u2010, and heptachlorohydroxydiphenyl ethers in mice","publication_year":1983,"publication_date":"1983-08-01","ids":{"openalex":"https://openalex.org/W2017102736","doi":"https://doi.org/10.1080/15287398309530423","mag":"2017102736","pmid":"https://pubmed.ncbi.nlm.nih.gov/6655733"},"language":"en","primary_location":{"id":"doi:10.1080/15287398309530423","doi":"https://doi.org/10.1080/15287398309530423","is_oa":false,"landing_page_url":"https://doi.org/10.1080/15287398309530423","pdf_url":null,"source":{"id":"https://openalex.org/S85071590","display_name":"Journal of Toxicology and Environmental Health","issn_l":"0098-4108","issn":["0098-4108","1087-2620"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","norway-1","poland-70"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Toxicology and Environmental Health","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111644923","display_name":"Terry L. Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131249849","display_name":"Oregon State University","ror":"https://ror.org/00ysfqy60","country_code":"US","type":"education","lineage":["https://openalex.org/I131249849"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Terry L. Miller","raw_affiliation_strings":["Department of Agricultural Chemistry and Environmental Health Sciences Center, Oregon State University, Corvallis, Oregon, 97331"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Agricultural Chemistry and Environmental Health Sciences Center, Oregon State University, Corvallis, Oregon, 97331","institution_ids":["https://openalex.org/I131249849"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090625182","display_name":"David J. Lorusso","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131249849","display_name":"Oregon State University","ror":"https://ror.org/00ysfqy60","country_code":"US","type":"education","lineage":["https://openalex.org/I131249849"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David J. Lorusso","raw_affiliation_strings":["Department of Agricultural Chemistry and Environmental Health Sciences Center, Oregon State University, Corvallis, Oregon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Agricultural Chemistry and Environmental Health Sciences Center, Oregon State University, Corvallis, Oregon","institution_ids":["https://openalex.org/I131249849"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112710813","display_name":"Marilyn L. Walsh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131249849","display_name":"Oregon State University","ror":"https://ror.org/00ysfqy60","country_code":"US","type":"education","lineage":["https://openalex.org/I131249849"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marilyn L. Walsh","raw_affiliation_strings":["Department of Agricultural Chemistry and Environmental Health Sciences Center, Oregon State University, Corvallis, Oregon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Agricultural Chemistry and Environmental Health Sciences Center, Oregon State University, Corvallis, Oregon","institution_ids":["https://openalex.org/I131249849"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028137180","display_name":"Max L. Deinzer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131249849","display_name":"Oregon State University","ror":"https://ror.org/00ysfqy60","country_code":"US","type":"education","lineage":["https://openalex.org/I131249849"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Max L. Deinzer","raw_affiliation_strings":["Department of Agricultural Chemistry and Environmental Health Sciences Center, Oregon State University, Corvallis, Oregon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Agricultural Chemistry and Environmental Health Sciences Center, Oregon State University, Corvallis, Oregon","institution_ids":["https://openalex.org/I131249849"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I131249849"],"apc_list":null,"apc_paid":null,"fwci":0.9709,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.65228932,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"12","issue":"2-3","first_page":"245","last_page":"253"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":0.7470999956130981,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":0.7470999956130981,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10875","display_name":"Pesticide Exposure and Toxicity","score":0.15600000321865082,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10447","display_name":"Environmental Toxicology and Ecotoxicology","score":0.025299999862909317,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-toxicity","display_name":"acute toxicity","score":0.9419999718666077},{"id":"https://openalex.org/keywords/ld50","display_name":"LD50","score":0.9430000185966492},{"id":"https://openalex.org/keywords/intraperitoneal-administration","display_name":"intraperitoneal administration","score":0.7419999837875366},{"id":"https://openalex.org/keywords/hypothermia","display_name":"hypothermia","score":0.7459999918937683},{"id":"https://openalex.org/keywords/cns-depressant-effects","display_name":"central nervous system depressant effects","score":0.9190000295639038},{"id":"https://openalex.org/keywords/triclosan","display_name":"triclosan","score":0.7940000295639038},{"id":"https://openalex.org/keywords/pentachlorophenol","display_name":"pentachlorophenol","score":0.8569999933242798}],"concepts":[{"id":"https://openalex.org/C97343561","wikidata":"https://www.wikidata.org/wiki/Q18026873","display_name":"HEXA","level":2,"score":0.927118718624115},{"id":"https://openalex.org/C116263406","wikidata":"https://www.wikidata.org/wiki/Q3299024","display_name":"Acute toxicity","level":3,"score":0.5575926303863525},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.546805739402771},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33280766010284424},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.31765466928482056},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.3118053078651428},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24833032488822937}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001831","descriptor_name":"Body Temperature","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006843","descriptor_name":"Hydrocarbons, Chlorinated","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D007928","descriptor_name":"Lethal Dose 50","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010647","descriptor_name":"Phenyl Ethers","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055768","descriptor_name":"Halogenated Diphenyl Ethers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1080/15287398309530423","doi":"https://doi.org/10.1080/15287398309530423","is_oa":false,"landing_page_url":"https://doi.org/10.1080/15287398309530423","pdf_url":null,"source":{"id":"https://openalex.org/S85071590","display_name":"Journal of Toxicology and Environmental Health","issn_l":"0098-4108","issn":["0098-4108","1087-2620"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","norway-1","poland-70"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Toxicology and Environmental Health","raw_type":"journal-article"},{"id":"pmid:6655733","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6655733","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of toxicology and environmental health","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1983962991","https://openalex.org/W1989633902","https://openalex.org/W1994753965","https://openalex.org/W2003087995","https://openalex.org/W2006755994","https://openalex.org/W2024892239","https://openalex.org/W2034786301","https://openalex.org/W2051873660","https://openalex.org/W2071167828","https://openalex.org/W2111404249","https://openalex.org/W2132185702","https://openalex.org/W2171965758","https://openalex.org/W2217008023","https://openalex.org/W2335757080","https://openalex.org/W2396528288","https://openalex.org/W2401188729","https://openalex.org/W2415260745"],"related_works":["https://openalex.org/W2171965758","https://openalex.org/W2011164579","https://openalex.org/W2080431604","https://openalex.org/W2125464524","https://openalex.org/W7128206050","https://openalex.org/W1968370605","https://openalex.org/W193227718","https://openalex.org/W2044165644","https://openalex.org/W2144968850","https://openalex.org/W2013892982"],"abstract_inverted_index":{"The":[0,18,64],"acute":[1,19,47],"intraperitoneal":[2],"LD50":[3],"values":[4],"of":[5],"various":[6],"hydroxychlorodiphenyl":[7],"ethers":[8],"(HO-ClX-DPEs;":[9],"X":[10],"=":[11,84],"5-7)":[12,85],"in":[13],"mice":[14],"have":[15,57],"been":[16,58],"determined.":[17],"toxicities":[20,48],"observed":[21,32,59],"were":[22,53],"on":[23,91],"the":[24,46,81,92],"order":[25],"of,":[26],"or":[27],"slightly":[28],"less":[29,55],"than,":[30],"that":[31,73],"previously":[33],"for":[34,50,60],"2-hydroxy-2',4,4'-trichlorodiphenyl":[35],"ether":[36],"(2-HO-Cl3-DPE;":[37],"Irgasan":[38],"DP-300;":[39],"Triclosan),":[40],"a":[41,67,87],"commonly":[42],"used":[43],"bactericide.":[44],"However,":[45],"determined":[49],"these":[51],"compounds":[52],"substantially":[54],"than":[56],"HO-Cl9-DPEs":[61],"and":[62],"pentachlorophenol.":[63],"HO-ClX-DPEs":[65,82],"had":[66],"marked":[68],"hypothermic":[69],"effect,":[70],"similar":[71],"to":[72,80],"produced":[74],"by":[75],"2-HO-Cl3-DPE.":[76],"Symptomatology":[77],"following":[78],"exposure":[79],"(X":[83],"suggested":[86],"nonspecific":[88],"depressant":[89],"effect":[90],"central":[93],"nervous":[94],"system.":[95]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}